Gholam Reza Mahdavinia

University of Maragheh · Department of Chemistry

Advances in the nanotechnology fields provided crucial applications in plant sciences, contributing to the plant performance and health under stress and stress-free conditions. Amid the applications, selenium (Se), chitosan and their conjugated forms as nanoparticles (Se-CS NPs) have been revealed to have potential of alleviating the harmful effect...

Recently, nanoclay-based nanocomposites have gained much attentions in the preparation of drug delivery systems due to their excellent physicochemical properties. Herein, by the combination of magnetic laponite RD (laponite rapid dispersion; Lap) nanodiscs and chitosan (CS)/κ-carrageenan (Car) biopolymers, core–shell nanocarriers were fabricated to...

Combining natural antioxidants with synthetic anticancer agents is a helpful approach in chemotherapy to reduce side effects and enhance the effectiveness of drugs. Saffron extract (SAF), a natural antioxidant with anti-cancer properties, bears a protective effect against doxorubicin-induced toxicity. Co-delivery of doxorubicin (DOX), a known antic...

Combining non-toxic biomaterials to obtain high effective hybrids is a promising approach in medicine and drug delivery. This study aims to combine the biomaterial with different swelling behavior to attain high controlled release. Hydroxyapatite (HA) nanoparticles do not possess swelling properties and are stable in different pH solutions. HA was...

Phenol is a hazardous organic solvent to living organisms, even in its small amounts. In order to bioremediation of phenol from aqueous solution, a novel bacterial strain was isolated from coking wastewater, identified as Rhodococcus qingshengii based on 16S rRNA sequence analysis and named as strain Sahand110. The phenol-biodegrading capabilities...

The control of the two-spotted spider mite, Tetranychus urticae Koch as one of the most important key pests in agriculture, is basically dependent on the use of pesticides. The lethal and sublethal impact of cyflumetofen (Danisaraba ®) and bromopropylate (Neoron ®) were assessed. LC50 values of cyflumetofen and bromopropylate were 2.77 and 8.95 µg...

The renewable, proteinaceous, marine biopolymer spongin is yet the focus of modern research. The preparation of a magnetic three-dimensional (3D) spongin scaffold with nano-sized Fe3O4 cores is reported here for the first time. The formation of this magnetic spongin–Fe3O4 composite was characterized by X-ray diffraction (XRD), thermogravimetric ana...

The production and sustainability of grape berries with high quality and health-promoting properties is a major goal. In this regard, nano-engineered materials are being used for improving the quality and marketability of berries. In this study, we investigated the potential role of chitosan–phenylalanine nanocomposites (CS–Phe NCs) in improving th...

In this study, a pH-responsive drug carrier was developed for the controllable release of drugs in the gastric environment. Chitosan (CS), a pH-sensitive biopolymer, and laponite RD (LAP), a nano-clay with a high drug-loading capability, were used to design the new carrier. Hydroxyapatite (HA) was grafted into CS/LAP matrix through a simple co-prec...

The present study aimed to develop an easy controlled release system for salicylic acid (SA) through ionotropic gelation of chitosan (CTS) using tripolyphosphate (TPP) as cross-linker. The synthesized nanoparticles (SA/CTS NPs) were characterized for their physicochemical properties by various techniques including Fourier transform infrared spectro...

In this study, cryogel nanocomposite based on poly (vinyl alcohol) (PVA) in situ formed zinc oxide nanoparticles (ZnO NPs) in the presence of fulvic acid (FA) was fabricated via repeated freeze-thawing method. Fourier transformed infrared spectroscopy (FTIR) was used for chemical elucidation of the prepared samples. The surface morphologies of bare...

In this study, pH-responsive hydrogels based on PVA-boronate crosslinks were prepared via a simple route and used for controlled and targeted delivery of anticancer drug methotrexate. A double network (DN) hydrogel composed of didiol-boronate/PVA complex as the first network and PVA crystallites generated by a freeze-thaw process as the second one...

This work aimed to design montmorillonite-incorporated pH-responsive and magnetic κ-carrageenan/chitosan hydrogels via a completely green route for controlled release of sunitinib anticancer drug. This was accomplished by ionic cross-linking of two biopolymers, κ-carrageenan and chitosan, in the presence of magnetic montmorillonite (mMMt) nanoplate...

This study reports developing novel smart drug delivery systems (DDS) that have great importance in anticancer therapeutics. The magnetic hydroxypropyl methylcellulose (mHPMC) synthesized via in situ method and introduced in the fabrication of tripolyphosphate (TPP)-cross-linked chitosan core-shell nano-carriers ([email protected]). The TPP-cross-l...

This work describes the development of novel pH-sensitive nanoparticles (NPs) for the delivery of melatonin (MLT) in breast cancer therapy. The MLT was encapsulated in composite NPs consisting of chitosan (CTS) and hydroxypropyl methylcellulose (HPMC) cross-linked in the presence of tripolyphosphate (TPP). The structure of the composite NPs was cha...

Dyes are scientifically and generally a new type of environmental pollutions, which has caused worldwide concern. Many research has been done in this field to remove dyes from wastewater based on the adsorption process via nano-adsorbents. This study described the synthesis of a new magnetic nano-adsorbent based on chitosan hydrogel beads to remove...

Nanoencapsulation of an acaricide, clofentezine, was investigated through a simple and green route using polyethylene glycol (PEG). In comparison to conventional formulations of clofentezine, clofentezine nanocapsules (Clo@NPs) showed improved persistence and solubility. TEM showed spherical nanoparticles that were 230 ± 20 nm. The LC50 values for...

Tillage not only affects the quantity of soil organic carbon, SOC, but also its quality. Therefore, an investigation was conducted to see how a five-year (2011–2016) implementation of conventional tillage, CT, and conservation tillage practices, CTP’s, under dryland vetch – wheat farming system can affect the total organic carbon, TOC, of soil and...

This work reports the synthesis of novel antibacterial magnetic-/pH-sensitive hydrogel beads based on ionotropic-gelation of alginate biopolymer. Using pomegranate peels extract, green-Ag nanoparticles were synthesized inside a mixture of alginate and Fe3O4, via in situ method. The alginate beads were investigated by VSM, TEM, XRD, and FE-SEM techn...

In this study, magnetic sepiolite (mSep) was incorporated into the poly(vinyl alcohol) (PVA) biopolymer to develop a cost-effective and ecofriendly nanocomposite adsorbent. The prepared nanocomposites were characterized using Fourier-transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), transmission electron microscopy (TEM) a...

In this study, magnetic bio-adsorbent based on chitosan with high molecular weight was prepared. To stabilize under acidic condition, the synthesized magnetic chitosan was cross-linked with κ-carrageenan (mChitoCar). The magnetic bio-adsorbent was characterized by scanning electron microscopy, transmission electron microscopy, and X-ray diffraction...

Due to the biodegradability and biocompatibility, the hydrogel biomaterials generated from poly(vinyl alcohol) (PVA) are widely used in the biomedical fields. Introducing modified magnetic nanoparticles in PVA-based hydrogels is an efficient route to improve their protein adsorption behavior. Herein, a novel well-developed porous magnetic PVA/lapon...

Although the traditional hydrogels have shown great potential applications in designing drug delivery systems, the burst release of drugs remains an issue. In this work, we develop and evaluate a sustained release of ciprofloxacin using chitosan/hydroxyapatite/κ-carrageenan complexes. The size and structure of HA nanoparticles were characterized by...

Essential oils are promising candidates for the substitution of synthetic pesticides owing to their pesticidal and pest repellent features and also lower environmental side effects. Despite the pesticidal effects, the most of essential oils lose their effects against environmental conditions. Nanoformulation is a technique that may protect or impro...

The main objective of this work was to develop κ-carrageenan-crosslinked magnetic chitosan with different molecular weights as pH-responsive carriers for controlled release of anticancer drug sunitinib. The characterization of magnetic carriers revealed that the size of magnetic nanoparticles is affected by the molecular weight of chitosan. Drug en...

Magnetic chitosan/Cu–Mg–Al layered double hydroxide (mCSLDH) nanocomposite was prepared and copper(II) ions were immobilized in the prepared composite. The nanocomposite [(Cu-mCSLDH)] was characterized by FT-IR, XRD, VSM, AAS, EDX, SEM and TEM. The utility of nanocomposite was investigated in the one-pot three-component (A³) coupling of aldehydes,...

The objective of this study was the fabrication of encapsulated Satureja hortensis essential oil (S.EO) in chitosan/tripolyphosphate nanoparticles (CS/TPP-NPs) via ionic gelation technique and investigation of its acaricidal effect. A high encapsulation efficiency of 96.17% was obtained, which shows successful encapsulation of EOs in CS-TPP nanopar...

In this study, magnetic nanocomposite hydrogels based on polyvinyl alcohol were synthesized. Magnetic polyvinyl alcohol/laponite RD (PVA-mLap) nanocomposites were characterized by scanning electron microscopy, X-ray diffraction, transmission electron microscopy, and Fourier transform infrared spectroscopy. The results indicated that PVA-mLap had de...

Essential oils are promising candidates for the substitution of synthetic pesticides owing to their pesticidal and pest repellent features and also lower environmental side effects. Despite the pesticidal effects, the most of essential oils lose their effects against environmental conditions. Nanoformulation is a technique that may protect or impro...

Magnetic bioadsorbents based on chitosan with different molecular weights were prepared. To stabilize under acidic condition the synthesized magnetic chitosan was crosslinked with κ-carrageenan. The characterization of magnetic bioadsorbents revealed that the size of magnetic nanoparticles is affected by the chitosan molecular weight. Magnetic nano...

Chitosan-based magnetic beads were developed by solution-mixing method. Firstly, the Fe3O4 nanoparticles were in situ immobilized on laponite RD sheets. The magnetic laponite RD was then dispersed in PVA and mixed with chitosan solution. PVA was aimed to prevent the disintegration of chitosan under acidic media due to its ability to form hydrogel n...

The conventional covalently cross-linked double network (DN) hydrogels with high stiffness often show low toughness and self-healing property due to the irreversible bond breakages in their networks. Therefore, scarcity of hydrogels that possess simultaneous features of stiffness, toughness, and autonomous self-healing properties at the same time r...

Herein, magnetic nanocomposite hydrogels based on polyvinyl alcohol with enhanced adsorption capacity for methylene blue (MB) is reported. Magnetite nanoparticles were immobilized on negatively charged laponite RD sheets. Magnetic polyvinyl alcohol/laponite RD (mPVALap) nanocomposites were generated in a simple and eco-friendly route through disper...

The Cu2+ ions immobilized on a novel magnetic chitosan-based catalytic system by combination laponite RD was prepared. CuII-magnetic chitosan/laponite RD (Cu-mCSLap) nanocomposite was characterized by X-ray diffraction analysis, energy dispersive X-ray Analysis, scanning electron microscope and transmission electron microscope. Further, we tested t...

Please cite this article as: Babaahmadi M, Sabzi M, Mahdavinia GR, Keramati M, Preparation of amorphous nanocomposites with quick heat triggered shape memory behavior, Polymer (2017), ABSTRACT The aim of this work was to prepare shape memory materials from poly(vinyl acetate) (PVAc), a low-cost commercial polymer, through the simple solution mixing...

Chitin, a polysaccharide, is abundant in nature and this substrate can be easily hydrolyzed by chitinase. Pharmaceutical and industrial applications of chitinase are considerably noteworthy, therefore in this study, high scale production of Chit36 enzyme was targeted using the E. coli pET expression system. The purified Chit36 enzyme was immobilize...

The present study highlights the fabrication of novel food-grade hydrogel particles based on pectin and starch for probiotic colon delivery. Lactobacillus plantarum ATCC:13643 (L. plantarum) cells were encapsulated in pectin/starch hydrogel by extrusion method. Four batches were formulated with different ratios of starch/pectin solutions. Optical a...

The aim of the present work was to develop green carriers for methotrexate using κ-carrageenan/chitosan complexes. Magnetic Fe3O4 nanoparticles were first synthesized in the presence of κ-carrageenan through in situ method. Then, the obtained magnetic κ-carrageenan was crosslinked using the polycation chitosan biopolymer. The physical and structura...

This study reports a novel carrier based on blends of carboxymethyl cellulose (CMC) and k-Carrageenan (k-Carr) for probiotic colon delivery. Lactobacillus plantarum ATCC:13643 (L. plantarum) cells were encapsulated in CMC/k-Carr blends by extrusion method. k-carrageenan was used as a coating agent to improve encapsulation of L. plantarum cells in c...

Here strong electroactive shape memory nanocomposites are prepared by incorporating graphene nanoplatelets into poly(vinyl acetate) (PVAc) through the simple solvent mixing method. Transmission electron microscopy (TEM) and X-ray diffraction (XRD) revealed that well exfoliated graphene nanoplatelets were formed a continuous network throughout the m...

Films of chitosan/polyvinyl alcohol (PVA)/sepiolite nanocomposite were prepared by a simple and ?green? route through solution mixing; followed by freezing?thawing cycles. The structures of nanocomposites were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), thermogravimetric analysis, X-ray diffractometr...

A new polymeric laponite nanoclay heterogeneous catalytic system based on HPMC (hydroxypropyl methyl cellulose) was developed for direct Mannich-type reaction of ketones with substituted benzaldehydes and anilines to afford corresponding β-amino ketones in good to high yields. Interestingly, cyclic ketones exhibited different chemoselectivity. Cycl...

The objective of this investigation was to prepare magnetic bionanocomposite adsorbents based on κ-carrageenan using a simple and efficient method. The magnetic κ-carrageenan was prepared through in situ method and was crosslinked by chitosan polysaccharide through electrostatic attractions. The magnetic bionanocomposites were assessed as adsorbent...

In this study double physically crosslinked magnetic hydrogel beads were developed by a simple method including solution mixing of sodium alginate and poly(vinyl alcohol) (PVA) containing magnetic laponite RD (Rapid Dispersion). Sodium alginate and PVA were physically crosslinked by Ca2+ and freezing-thawing cycles, respectively. Magnetic laponite...

Magnetic amidoximated nanocomposites based on a combination of chitosan and magnetic laponite RD were prepared and examined for the removal of Cu²⁺ from aqueous solutions. Magnetic laponite RD was prepared by an in situ method. In order to prepare magnetic amidoximated nanocomposites, acrylonitrile was grafted to chitosan in the presence of magneti...

This paper describes preparation of novel magnetic and pH-sensitive nanocomposite beads through an environmentally friendly route for protein adsorption. Magnetic Fe3O4 nanoparticles (MNPs) were modified by a binary mixture of κ-carrageenan/carboxymethyl chitosan biopolymers. The structural and adsorption properties of new product were confirmed by...

We synthesized novel magnetic nanocomposite hydrogels of κ-carrageenan by incorporating magnetic laponite RD. The magnetite nanoparticles were embedded in laponite RD through in situ method. The structure of nanocomposites were characterized using X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and vibrating sampl...

In this study, novel magnetic chelating ligands focused on Cu2þ removal from aqueous solutions were synthesized. The magnetic adsorbents were obtained by amidoximation of nitrile groups on starch-g-polyacrylonitrile/montmorillonite/Fe3O4. The magnetic Fe3O4 nanoparticles were obtained in situ in the presence of montmorillonite clay. The structure o...

This paper reports the synthesis of magnetic and pH-sensitive beads derived from kappa-carrageenan and carboxymethyl chitosan for drug delivery. The magnetic Fe3O4 nanoparticles were synthesized inside a mixture of biopolymers by in situ method. The structural properties of hydrogel beads were characterized by TEM, SEM, XRD, and VSM techniques. The...

This investigation reports the synthesis of magnetic nanocomposite hydrogels based on carboxymethyl chitosan-g-poly(acrylamide) (CMC-g-PAAm). The magnetic nanoparticles were prepared via in situ co-precipitation of iron salts in the presence of laponite RD nanoclay. Different contents of magnetic nanoclay were utilized to prepare magnetic CMC-g-PAA...

A novel nanocomposite hydrogel prepared by incorporating Fe3O4 magnetic nanoparticles into the κ-carrageenan-g-poly (methacrylic acid) with in situ polymerization and was characterized by FT-IR, XRD, SEM, TEM and VSM. Synthesized nanocomposite was used to adsorb Crystal Violet (CV) (cationic dye) in aqueous solution in a batch system. The research...

In this study, novel kappa-carrageenan/poly(vinyl alcohol) nanocomposite hydrogels were developed by incorporating sodium montmorillonite nanoclay. The mixture of polymers and montmorillonite was crosslinked with freezing–thawing technique and subsequent with K+ ions. The structure of nanocomposite hydrogels was characterized with the FTIR, SEM, XR...

A green rout to prepare magnetic-,pH-responsive beads

In this work, the magnetic nanocomposite hydrogels that focused on targeted drug delivery were synthesized by incorporation of polyvinyl alcohol (PVA), kappa-carrageenan (Cara), and magnetite Fe3O4 nanoparticles. The magnetic nanoparticles were obtained in situ in the presence of a mixture of polyvinyl alcohol/kappacarrageenan (CaraPVA). The produc...

This work describes the preparation of magnetic and pH-sensitive beads based on κ-carrageenan and sodium alginate for use as drug-targeting carriers. Physical cross-linking using K(+)/Ca(2+) ions was applied to obtain ionic cross-linked magnetic hydrogel beads. The produced magnetite beads were thoroughly characterized by TEM, SEM/EDS, XRD, FTIR, a...

In this study, magnetic nanocomposite hydrogels were synthesized by incorporation of kappa-carrageenan, polyvinyl alcohol (PVA), and magnetic Fe3O4 nanoparticles. Magnetite nanoparticles were prepared in the presence of a mixture of kappa-carrageenan/PVA (CaraPVA) via in situ co-precipitation method. For preparation of hydrogels, the synthesized ma...

In the current study, influences of chitosan solutions on morphological characteristics, growth and yield components of lentil (Lens culinaris Med.) under rainfed conditions have been investigated. A field experiment was conducted in the Northwest of Iran using a split-plot experiment based on a completely randomized design with three replications....

Biopolymer-based magnetic beads, composed of kappa-carrageenan (κ-Car) and Fe3O4 nanoparticles, were synthesized. The magnetic beads were prepared through in situ precipitation of Fe2+/Fe3+ ions in the presence of carrageenan and subsequently treating with K+ solution. The structure of magnetic kappa-carrageenan beads (mκ-Carb) was characterized by...

Purpose – The paper introduces a new method for single step synthesis of copper phthalocyanine green pigment using microwave irradiation to activate C−H bonds on the aromatic rings that are possible by creation of chlorine radicals. The aims of this study are to investigate the possibility of high-efficiency product reaction, removing acidic wastew...

Nanocomposite hydrogels were synthesized from grafting of acrylamide onto hydroxypropyl methylcellulose using methylenebisacrylamide cross-linker and laponite RD nanoclay. An unusual swelling was observed in CaCl2 solutions. The structure of nanocomposites was characterized by XRD, SEM, FTIR, and TEM techniques. The nanocomposite hydrogels were eva...

Nanocomposite hydrogels were synthesized by solution copolymerization of acrylamide (AAm) in the presence of kappa-carrageenan (Carra) biopolymer and sodium montmorillonite (Na-MMt) nanoclay. The structure and morphology of the nanocomposites were investigated using XRD and scanning electron microscopy (SEM). The obtained nanocomposites were examin...

K+-Cross-linked kappa-Carrageenan beads were prepared and the dried and wet beads of cross-linked carrageenan were evaluated to remove the cationic crystal violet (CV) dye from water. The kinetics and mechanism of CV adsorption onto both wet and dried carrageenan beads were studied. The effect of contacting time and initial concentration of CV on a...

Ab initio calculations are performed to analyse the existence of intermolecular halogen···π interactions in NCX complexes with YC≡CY, where X = Cl, Br and Y = H, CN, F, Cl, OH, NH2, and CH3. Molecular geometries and interaction energies of the complexes are investigated at the MP2/aug-cc-pVTZ level of theory. Our results indicate that the interacti...

In this study, nanocomposite hydrogels from grafting of acrylamide onto kappa-carrageenan biopolymer were prepared in the presence of sepiolite clay. Methylenebisacrylamide and ammonium persulfate were used as cross-linker and initiator, respectively. The sepiolite nanoclay was introduced into hydrogel matrix without any chemical treatment. The str...

Hydrogel nanocomposites were synthe-sized from grafting of acrylamide onto hydroxypropyl methylcellulose using methylenebisacrylamide cross-linker and sodium montmorillonite (Na-MMt) nano-clay. The effect of nanoclay content on the swelling of nanocomposites was investigated and an optimum swelling capacity was obtained at 12.7 wt% of Na-MMt. The e...

A density functional theory study was carried out to predict the relative reactivities of different sites on the external surface of pristine and nitrogen-doped carbon nanocones (CNCs). The properties determined include the electrostatic potential VS(r) and average local ionization energy I(r) on the surfaces of the investigated CNCs. Our results r...

Nanocomposite superabsorbents were synthesized by simultaneously solution copolymerization of acrylamide (AAm) and sodium acrylate (Na-AA) in the presence of carrageenan biopolymer and sodium montmorillonite (Na-MMt) nanoclay. Potassium persulfate (KPS) and methylenebisacrylamide (MBA) were used as initiator and crosslinker, respectively. The struc...

Novel hydrogel nanocomposites were synthesized by solution polymerization of acrylamide in the presence of carrageenan biopolymer and laponite RD clay. Laponite was used as an inorganic cross-linker. Ammonium persulfate was applied as an initiator. The structure and morphology of the nanocomposites were investigated using XRD, scanning electron mic...

Nanocomposite superabsorbents were prepared from solution polymerization of sodium acrylate in the presence of carrageenan biopolymer and sodium montmorillonite nanoclay. The optimum swelling of nanocomposite superabsorbents was achieved at 8 wt% of sodium montmorillonite nanoclay. Clay-free superabsorbent and nanocomposite containing 8 wt% of nano...

Nanocomposite superabsorbents were synthesized by graft copolymerization of mixture of acrylamide (AAm) and acrylic acid (AA) onto collagen using potassium persulfate (KPS) as a free radical initiator and methylenebisacrylamide (MBA) as a crosslinker. Nanoclay sodium montmorillonite (MMt) was introduced as filler into superabsorbent. The chemical s...

A novel superabsorbent nanocomposite based on hydrolyzed collagen was synthesized by simultaneously graft copolymerization of 2-acrylamido-2-methylpropane sulfonic acid (AMPS) and acrylamide (AAm). Sodium montmorilonite (Na-MMt) was used as clay. Methylenebisacrylamide (MBA) and ammonium persulfate (APS) were used as crosslinker and initiator, resp...

Inclusion of nano-clays into hydrogels is an efficient approach to produce nanocomposite hydrogels. The introduction of nano-clay into hydrogels causes an increase in water absorbency. In the present work, Nanocomposite hydrogels based on kappa-carrageenan were synthesized using sodium montmorillonite as nano-clay. Acrylamide and methylenebisacryla...