Ghizal Fatima

Era's Lucknow Medical College and Hospital · Department of Biotechnology

Background: Recently, chronic lung diseases have been found to be associated with marked inflammation and oxidative stress, which leads to fibrosis in the lungs and chronic respiratory failure. This study aims to determine if hydrogen-rich water (HRW) can enhance oxygen saturation among patients with chronic lung diseases. Methods: Ten patients wit...

Objective: The aim: To study the clinical and the genetic association of 5-HTTVNTR and the 5-HTTLPR polymorphisms in women with FMS. Patients and methods: Materials and methods: 105 FMS patients and 105 controls were enrolled in the study. Polymerase chain method was used to analyse the 5-HTTLPR & 5-HTTVNTR gene polymorphism. The psychopathology...

Bioactive compounds are the food constituents, providing beneficial health effects to functional foods and nutraceuticals. These compounds have antioxidants activity including anti-inflammatory, antifungal, and have additional preventative actions. Since these compounds are important constituents enhancing function of the foods, therefore, these co...

The sustainable development goals(SDG) of the UNO would be difficult to achieve without prevention of metabolic diseases and other non-communicable diseases (NCDs). Western diet and lifestyle, which are major risk factors of NCDs, are known to cause oxidative stress and decrease in production of molecular hydrogen in the intestines which leads to a...

Objective: To study the five mutations commonly prevalent in North India, i.e., IVS-I-5 (G→C), 619 bp deletion, IVS-I-1 (G→T), codon 41/42 (-TTCT), and codon 8/9 (+G), in the beta thalassemia (β-thalassemia) major children. The specific β-thalassemia mutations of different haplotype patterns of the β-globin gene cluster will also be determined. M...

Background: Dementia has become a public health problems due to its association with behavioural risk factors; smoking, alcoholism, sedentary behaviour, western type diet, obesity, diabetes, and hypercholesterolemia. Most of these behavioural risk factors appear to be associated with dementia as well as with risk of cardiovascular diseases (CVDs) a...

There is evidence that behavioral risk factors such as western type diet, and life style can predispose to oxidative stress, deficiency in antioxidant status, hyperglycemia, dyslipidemia and increase in inflammation in tissues of various organs: beta cells of the pancreas, LDL receptors in the hepatocytes, endothelium, neurons, osteocytes and gut....

High-quality Indo-Mediterranean foods are characterised with unrefined, unprocessed foods, whole grains such as dry millets and beans and porridge. Vegetables such as leaves and gourds, nuts and fruits such as apples, grapes, papaya, guava, etc are major components of this diet. It seems that healthy vegetable oils such as olive, mustard, rape seed...

Background/Aim: Dementia has become a public health problem due to its association with biological risk factors; obesity, diabetes, hypertension and hypercholesterolaemia. Most of these risk factors, appear to be associated with dementia as well as with risk of coronary artery diseases (CADs) and stroke. This study aimed to find out the association...

Citation: Singh, R.B.; Nabavizadeh, F.; Fedacko, J.; Pella, D.; Vanova, N.; Jakabcin, P.; Fatima, G.; Horuichi, R.; Takahashi, T.; Mojto, V.; et al. Dietary Approaches to Stop Hypertension via Indo-Mediterranean Foods, May Be Superior to DASH Diet Intervention. Nutrients 2023, 15, 46. https:// Abstract: Western-type diet with high salt and sugar, s...

Objective: The aim: To determine the clinical and the genetic association of the COMT rs4680 SNP in women with FMS. Patients and methods: Materials and methods: Extracted DNA from peripheral blood samples were utilized as template for the PCR and RFLP analysis. Results: Results: A significant difference was found in the distribution of the COM...

There is evidence that behavioral factors, in particular western diet can predispose dementia, whereas mediterranean type of diet is protective. It seems that, early diagnosis of dementia is possible among patients consuming these diets, in particular among elderly population. This study aims to find out the association of dietary patterns in a urb...

The exact pathophysiology of heart failure (HF) is not yet known. Western diet, characterized by highly sweetened foods, as well as being rich in fat, fried foods, red meat and processed meat, eggs, and sweet beverages, may cause inflammation, leading to oxidative dysfunction in the cardiac ultra-structure. Oxidative function of the myocardium and...

Purpose Vitamin D receptor (VDR) has been proposed as a possible marker for fibromyalgia syndrome (FMS). The purpose of this study is to characterize the expression pattern of BsmI polymorphism (rs1544410) in the VDR gene in women with FMS and the genotype-phenotype association. Methods A total of 105 FMS patients and 105 controls were included in...

Heart failure (HF) has become a public health problem, but exact pathophysiology is still unknown. Western diet characterised with high sugar, high fat, red meat and processed meat, eggs, fried foods and sweetened beverages, may cause oxidative stress and inflammation, leading to oxidative dysfunction and adverse effects on cardiac-ultra-structure....

Insulin resistance (IR), secretion of insulin, and abnormalities of lipid metabolism are all markers of type 2 diabetes (T2DM), which is a progressive and complex metabolic disorder. Major risk factors for the development of T2DM were identified as genetic, environmental, and lifestyle factors. Several studies found that many genes contribute to T2...

Sudden cardiac death (SCD) in sports is defined as unexpected death during exercise or shortly after physical exertion (within 24 hours of exercise cessation) in athletes who appeared perfectly healthy otherwise. To highlight the importance of cardiovascular screening in athletes for reducing incidences of SCD, we performed a prospective study and...

Background: Since, behavioural factors can also predispose dementia, there is an unmet need to develop methods for its early diagnosis, which appears to be crucial for its prevention. This study aims to find out the prevalence of dementia, emphasizing on early symptoms, to validate a new modified questionnaire. Study Design and Setting. Cross-secti...

Epidemiological studies indicate that skipping breakfast as a universal behavior, may have adverse effects on cardiovascular diseases [CVDs}and metabolic diseases. However, eating breakfast regularly, may increase satiety, thereby reducing overeating later in the day which prevents weight gain. Recent studies indicate that skipping breakfast increa...

The immune system is comprised of lymph glands, lymph nodes, thymus gland, spleen, bone marrow, lymphocytes, and molecules such as antibodies and cytokines. It has a vast array of functionally different cells such as T and B lymphocytes, macrophages, neutrophils and mast cells. The ontogenesis of the immune system is comprised of the innate immune...

The aim: The present study was carried out on patients recovered from COVID-19, including those patients who have taken vaccine and those who have not. Materials and methods: The patients were recruited via an online panel and surveyed at different regions of Iraq from June 1, 2021, to August 30, 2021. Results: Our results demonstrated that the hig...

Background Several psychiatric disorders have been found associated with serotonin transporter gene polymorphisms. The purpose of this study was to explore the correlation between serotonin gene polymorphism (5-HTTLPR & 5-HTTVNTR) in North Indian Women with Fibromyalgia Syndrome (FMS). Results 105 FMS patients and 105 controls were enrolled in the...

The Seven Countries Study showed that traditional Japanese and Mediterranean diets are protective against cardiovascular diseases (CVDs). The Japanese diet is considered the healthiest because it provides Japanese populations with the highest longevity and health. DASH and Mediterranean-style diets are also considered healthy diets, although the In...

The Seven Country study showed that traditional Japanese diet and Mediterranean diets are protective against cardiovascular diseases (CVDs). Japanese diet is considered the healthiest because it provides highest longevity and health to Japanese. DASH diet and Mediterranean style diets are also considered the healthy diets, although, it is possible...

Chronic heart failure (CHF) has different stages and includes pre-HF (PHF), a state of high risk of developing myocardial dysfunction and advanced CHF. Some major behavioral risk factors of PHF might predispose to biological risk factors such as obesity, diabetes mellitus, dyslipidemia, hypertension, myocardial infarction, and cardiomyopathy. These...

Industrialization and urbanization are associated with increased mental stress, increased consumption of ready-prepared Western-type foods, and sedentary, behavior leading to increased risk of non-communicable diseases (NCDs), including neurodegenerative diseases and psychological disorders. Epidemiological studies indicate that a Western diet, low...

The Greeks and the Romans knew that certain fruits that had entered the Mediterranean world were Persian in origin or came via Persia. The most famous of these were pistachio, peaches, pomegranates, grapes, figs, and dates. The Global Burden of Disease Study has demonstrated that 49% of deaths are related to unhealthy diet, including deaths due to...

Food security, as defined by the United Nations’ Committee on World Food Security, means that all people, at all times, have physical, social, and economic access to sufficient, safe, and healthy food that meets their food preferences and dietary needs for an active and healthy life. Food insecurity is defined as the disruption of food intake or ea...

Objective: The aim: The present study was carried out on patients recovered from COVID-19, including those patients who have taken vaccine and those who have not. Patients and methods: Materials and methods: The patients were recruited via an online panel and surveyed at different regions of Iraq from June 1, 2021, to August 30, 2021. Results:...

Background: Down syndrome (DS) is the commonest chromosomal anomalies at birth. DS is portrayed by the event of extra complete/deficient duplicate of chromosome number 21 (trisomy 21). Around the world, this disordered influencing roughly 1 out of 1000 infants. Pro-inflammatory and anti-inflammatory cytokines engaged with a few physiological proce...

Introduction:In this study we evaluated the connivance of oxidative and antioxidative parameters in the pathogenesis of spinal cord injury (SCI). Although the etiology and pathogenesis of SCI remain to be fully understood, it has been suggested that reactive oxygen species (ROS) and oxidative stress may play a significant role in the pathophysiolog...

This study aims to evaluate the effects of FTO gene polymorphism (rs17817449andrs1588413) as predictor/ risk factors of type 2 diabetes mellitus in obese Iraqi population. Four hundred obese participants clinically diagnosed with type 2 diabetes were enrolled in this study. A similar matching group of obese non-diabetic control group was also inclu...

Millions persons around the world are being associated with serious respiratory distress syndrome coronavirus-2 recognized as COVID-2 (SARS-CoV-2). Vitamin D deficiency also increased the chance COVID-19infections. Vitamin D works in the large number of functions for the human body alongside respiratory and immune system. Vitamin D does a significa...

To ward off the outbreak of the coronavirus disease (COVID‐19) in 2019, the Jordanian government applied quarantine to the Jordanian population in addition to Syrian refugees. We evaluated the quarantine's psychological effect on people in Jordan after three weeks of quarantine. The prevalence of post‐traumatic stress disorder (PTSD) in our sample...

Background Clopidogrel is an antiplatelet therapy that is widely used in pre and post percutaneous (PCI) coronary intervention procedures to prevent platelet aggregation and stent restenosis. However, there is a wide inter-individual variation in clopidogrel response and some patients showed resistance against the activity of Clopidogrel. Kinase in...

Background: There are few reports revealing association between iron intake and environmental lead exposure during pregnancy. Therefore, the present study was undertaken to investigate the effect of iron supplementation on biochemical modulation of certain lead toxicity markers associated with pregnancy. Methods: Iron and folic acid supplementation...

Cadmium (Cd), poisoning has been reported from all around the World, causing many deaths annually. Cd is a toxic heavy metal, and is widely present in environment. It has been reported that chronic Cd exposure is associated with kidney disease, osteoporosis, cardiovascular diseases and cancer. Smoking causes exposure to significantly higher Cd leve...

The purpose of the present paper is to study the Nephroprotective l effect of Quercttin in renal ischemia reperfusion mice model. The methods are forty male Swiss Albino mice 7-15 weeks weighting 30-35 gram (g) were divided into four groups, ten mice in each group, animal groups are arranged as, group I (Sham group) have been subjected to the same...

Objective In the present study we examined the connivance of oxidative and antioxidative parameters and toxic metal ion in women with FMS and also evaluated its correlation with the severity of its symptoms. Introduction FMS is a common chronic pain syndrome with an unknown etiology. Increased oxidative stress results from disparity between produc...

Objective In the present study we examined the connivance of oxidative and antioxidative parameters and toxic metal ion in women with FMS and also evaluated its correlation with the severity of its symptoms. Introduction FMS is a common chronic pain syndrome with an unknown etiology. Increased oxidative stress results from disparity between produc...

Purpose: In cervical spinal cord injury (CSCI), afferent and efferent circuits that influence the basal production of melatonin and cortisol may be disrupted and hence disrupt the basal functions of human physiology. Therefore, the aim of this study was to assess circadian changes, if any, in serum cortisol and melatonin in patients with CSCI. Me...

Cytokines (TNF-α and IL-6) levels are reported to be perturbed in Fibromyalgia syndrome (FMS) patients. Moreover, Body Mass Index (BMI) may also be related to disturbed cytokines level. Therefore, the present study was planned to evaluate the levels of cytokines and to correlate them with BMI and Fibromyalgia Impact Questionnaire Revised (FIQR) in...

In the present study we examined the involvement of oxidative and antioxidative parameters in women with fibromyalgia syndrome (FMS) and also evaluated their correlation with Fibromyalgia Impact Questionnaire Revised (FIQR). Oxidative stress was determined by measuring the levels of lipid peroxides (LPO) and protein carbonyls in plasma and antioxid...

Study design: Oxygen-derived free radicals have been implicated in the pathogenesis of spinal cord injury (SCI) after trauma. Objective: In this review we will elucidate the importance of oxidative stress and antioxidants and its possible relationship with SCI. Methods: Literature analysis of oxidative stress, antioxidative parameters based on...

Fibromyalgia Syndrome (FMS) is one of the least understood pain syndrome in medicine today, which is a chronic disorder characterized by persistent and widespread pain, with an estimated prevalence of 2–4 % in the adult general population (3.4 % for women and 0.5 % for men). The defining symptoms of FMS are chronic widespread pain and fatigue. Othe...

Aim: To estimate the frequency of recurrence of pregnancy induced hypertension in 2nd pregnancy. Study design: Descriptive case series Place and duration of study: The Department of Obstetrics & Gynecology, Unit- II, Sir Ganga Ram Hospital, Lahore. six month duration from Aug 01, 2009 to Feb 01, 2010. Methods: Eighty patients were selected in accor...

Background: Alterations in the sleep -wake cycle leads to decreased melatonin secretion and it may be associated with sleep disorders and cancer risk. Exposure of light at night and rotating night shift decrease the melatonin production due to acute suppression of pineal melatonin secretion during night work has been suggested to increases cancer r...

The aim of the present study was to evaluate circadian variation in serum serotonin (5-hydroxytryptamine; 5-HT) levels and correlate it with Tender Points Count (TPC) and Fibromyalgia Impact Questionnaire Revised (FIQR) in female fibromyalgia syndrome (FMS) patients. Serum levels of 5-HT were measured at 6-h intervals in 50 women with FMS satisfyin...

Fibromyalgia syndrome (FMS) patients have disturbed sleep patterns which may lead to altered circadian rhythm in serum cortisol secretion. The aim of this study was to assess circadian changes, if any, in serum cortisol levels in female patients with FMS. Cortisol levels were estimated every 6 h during 24 h period; in 40 female patients satisfying...

The present study was designed to test the hypothesis of a circadian variation in circulating levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in women with fibromyalgia syndrome (FMS). Serum levels of IL-6 and TNF-α were measured at 4 h intervals of the day in 50 women with FMS satisfying American College of Rheumatology criteria...

Trivalent chromium [Cr(III)] is widely used in tanning industrial processes. The population living in tanning industrial area is continuously exposed to Cr(III) which appears to be associated with both acute and chronic health problems. Therefore, the aim of this study was to evaluate the health risk with special reference to oxidative stress param...

The present article reports first time the use of solid-phase microextraction (SPME) and dispersive liquid-liquid microextraction (DLLME) to extract pregabalin (PRG) from urine and pharmaceutical formulations followed by GC-MS analysis after ethyl chloroformate (ECF) derivatization. PRG is an antiepileptic and analgesic drug, which is a structural...

Objective: To determine frequency of fetal macrosomia in obese pregnant women. Study design: Descriptive case series. Place and duration of study: Department of Obstetrics and Gynecology Unit III, Nishtar hospital Multan.Six months from 14thMarch 2010 to 13th September 2010. Material & methods: One hundred and seventy four women with singleton preg...

Fibromyalgia syndrome (FMS) is characterised by diffuse muscle pain, poor sleep and unrelenting fatigue. Individuals with FMS may also experience headaches, anxiety, depression, poor memory, numbness and tingling in the extremities, cold hands and feet, irritable bowel syndrome and lowered immune function. FMS is a common chronic pain syndrome of u...

Adenomatoid odontogenic tumour (AOT) is a rare benign odontogenic tumour characterized by a progressively slow growing pattern and symptomless behavior. The differential diagnosis between AOT and other odontogenic tumours, such as ameloblastoma, should be well conducted in order to avoid extensive ablative surgery. This report presents an unusual c...

Fibromyalgia syndrome (FMS) is a complex chronic condition causing widespread pain and variety of other symptoms. It produces pain in the soft tissues located around joints throughout the body. FMS has unknown etiology and its pathophysiology is not fully understood. However, abnormality in circadian rhythm of hormonal profiles and cytokines has be...

After the revision of the genus Lantana in Brazil by Silva (1999), Chamissos’s concept of the genus was re-established. Therefore, the species of Lantana sect. Sarcolippia and all the species with fruit with two pyrenos were excluded from Lantana and they were transferred to the genus Lippia. Moreover, Lippia bahiensis was transferred to Lantana an...

Lippia sect. Rhodolippia is characterized mainly by its coloured bracts which are dispersed with the fruit. In the so far unpublished revision of this section 34 species were recognized and 32 synonyms for 14 species at specific and intra-specific level were included. Characters taxonomic and nomenclatural notes are briefly discussed in the present...