Gheorghe Gina

Gheorghe Gina
Carol Davila University of Medicine and Pharmacy | UMF CD · Gastroenterologie si Hepatologie

Doctor of Medicine

About

31
Publications
12,934
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
167
Citations

Publications

Publications (31)
Article
Full-text available
Introduction and aim: Sleep disorders are highly prevalent in patients with liver cirrhosis. The aim of this study was to investigate the prevalence of restless legs syndrome (RLS), as well as its risk factors and possible predictors, in a cohort of patients with liver cirrhosis. Material and methods: We performed a cross-sectional prospective s...
Article
Full-text available
Introduction/aim: The aim of this study was to assess the prevalence of cognitive impairments and their association with sleep patterns in a cohort of patients diagnosed with chronic liver disease (CLD). Material and methods: The present paper is a prospective cohort study, carried out over a period of 12 months, among patients with various stag...
Article
Full-text available
Background: The COVID-19 pandemic has had a negative impact on the training process for resident physicians. The objective of this study was to evaluate the impact of the COVID-19 pandemic on professional training, and also the subjective perception of the levels of stress, anxiety, and depression among resident doctors specializing in gastroentero...
Article
Full-text available
Pancreatic cancer is one of the most aggressive malignant neoplastic diseases. The incidence and mortality rates of this disease vary depending on geographical area, which might be explained by the different exposure to risk factors. To improve the prognosis of patients with pancreatic cancer, different approaches are needed for an earlier diagnosi...
Article
Full-text available
The present study aims to assess the sleep characteristics and health-related quality of life (HRQOL) among patients with chronic liver diseases (CLDs), as well as the relationship between them. We conducted a prospective cross-sectional study, over a period of eight months, on patients with CLDs. Sleep was assessed by subjective tools (self-report...
Article
Full-text available
Ablation par radiofréquence endoscopique dans les tumeurs bilio-pancréatiques Les maladies néoplasiques malignes bilio-pancréa-tiques sont caractérisées par une évolution agressive et à faible taux de survie à 5 ans. La seule méthode théra-peutique à potentiel curatif reste le traitement chirur-gical. Malheureusement, un pourcentage très élevé de p...
Article
Full-text available
Background and Objectives: Polypharmacy is associated with drug–drug or food–drug interactions that may pose treatment difficulties. The objective of the study was to investigate the use of polypharmacy in hypertensive patients hospitalized in the Internal Medicine Clinic of a European referral hospital. Materials and Methods: We conducted a retros...
Article
Full-text available
Hepatic dysfunction in pregnant women is always challenging for the obstetrician, as the spectrum of hepatic abnormalities can be very large and have various implications, both for mother and fetus. There is a diagnostic and therapeutic polymorphism of hepatic dysfunction in pregnancy and insufficient knowledge related to the etiopathogenesis and e...
Article
Full-text available
and Ilie, Madalina (2021) "Quality of life and special issues in women with inflammatory bowel diseases, Madalina Ilie. Quality of life and special issues in women with inflammatory bowel diseases. A B S T R A C T Introduction. The impact of inflammatory bowel diseases (IBD) on the quality of life (QoL) of patients is significant and it has importa...
Article
Full-text available
Introduction. Ultrasound-guided (US-guided) percutaneous drainage (PD) of abdominal collections represents the first-choice alternative to surgical intervention. The aim of our study was to assess the efficacy and safety of PD of visceral and non-visceral abdominal collections by reviewing our personal experience over a period of 5 years. Material...
Article
Full-text available
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. They are potentially malignant, and have an unpredictable evolution. The origin of these tumors is in the interstitial cells of Cajal, which are cells that are interposed between the intramural neurons and the smooth muscle cells of the...
Article
Full-text available
Two different conditions are included in inflammatory bowel disease (IBD), Crohn's disease (CD) and ulcerative colitis (UC), being distinguished by chronic recurrence of gut inflammation in persons that are genetically predisposed and subjected to environmental causative factors. The normal structure of the gut microbiome and its alterations in IBD...
Preprint
Full-text available
Background: The impact of inflammatory bowel diseases (IBD) on quality of life (QoL) of patients is significant and has important social and professional consequences. Methods: We aimed to describe the patients’ perspective regarding the impact of IBD on their overall QoL and to evaluate the differences between men and women. An observational cross...
Article
Full-text available
Hepatic disease accounts for approximately 2 million deaths/year worldwide. Liver fibrosis, as the last stage of numerous chronic liver diseases, is one of the most relevant prognostic factors. The liver biopsy with the histopathological examination is considered to be the “gold standard” for the identification and staging of the hepatic fibrosis....
Article
Full-text available
Nowadays, humanity faces one of the most serious health crises, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The severity of coronavirus disease 2019 (COVID-19) pandemic is related to the high rate of interhuman transmission of the virus, variability of clinical presentation, and the absence of specific therapeutic met...
Article
Full-text available
Pancreatic cancer (PC) is one of the most aggressive forms of cancer. Negative prognosis is mainly due to the late diagnosis in advanced stages, when the disease is already therapeutically overcome. Studies in recent years have focused on identifying biomarkers that could play a role in early diagnosis, leading to the improvement of morbidity and m...
Article
Full-text available
Fever of unknown origin (FUO) is a diagnosis that describes a prolonged febrile illness without an established cause, despite investigations. From the first definition of the medical condition (given by Petersdorf and Beeson in 1961) the diagnostic criteria have changed over time, intending to improve the management and outcome of these patients. T...
Article
Full-text available
Despite major progress in the prevention and treatment of cardiovascular diseases, women remain an underdiagnosed and insufficiently treated group, with higher hospitalization and death rates compared to men. Obesity, more frequently encountered in women, raises the risk of metabolic syndrome and cardiovascular diseases as women age. There are some...
Article
Full-text available
Acute pericarditis is an inflammatory condition of the pericardium. The incidence of acute pericarditis is not exactly known, but it is estimated that this condition is found in 0.1-5% of patients hospitalized for chest pain. The main causes of pericarditis could be inflammatory, neoplastic, vascular, congenital, and idiopathic. For the diagnosis o...
Article
Full-text available
Myocarditis is an inflammatory disease of the myocardium, that can be produced by a multitude of infectious or noninfectious agents. The incidence rate of the disease is between 10 to 22 per 100,000 individuals. Among the infectious causes, viruses are considered to be the most frequent pathogens. Regarding the clinical presentation, viral myocardi...
Article
Full-text available
The new coronavirus, SARS-CoV-2, first identified in humans in Wuhan Province, China, in December 2019, has spread rapidly throughout the world, causing World Health Organization (WHO) to declare it a pandemic infection. This pathogenic agent belongs to the genus beta-coronavirus, alongside SARS (Severe Acute Respiratory Syndrome) and MERS (Middle...
Article
Full-text available
Introduction: Ankylosing spondylitis is a chronic inflammatory disorder which primarily affects the axial skeleton, the major characteristic of the disease being the early involvement of the sacroiliac joints. The condition manifests by chronic inflammatory back pain and, as the disease progresses, patients will develop extreme impairment of spinal...
Article
Full-text available
Despite considerable improvements in medical care over the past 25 years, cardiovascular disease (CVD) remains a major public health challenge. Dyslipidemias are one of the topics of greatest interest in cardiology. Decreasing serum cholesterol level is a central objective for preventing cardiovascular events. The current European Society of Cardio...
Article
Full-text available
The role of beta-adrenergic receptor antagonists in cardiovascular therapy has been the subject of various studies over time, these agents representing one of the oldest class of drugs used for the treatment of cardiovascular diseases. Although beta-blockers have been excluded from guidelines as the first-line therapy in essential hypertension, the...
Article
Full-text available
Androgenic alopecia is the most common form of hair loss, hair loss is progressively occurring, affecting all races. In addition to the major psychological impact and impairment of quality of life, patients with early androgenic alopecia may subsequently suffer from severe coronary heart disease and metabolic syndrome. Androgenic alopecia is a mult...
Article
Full-text available
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unknown etiology and incompletely elucidated pathogenesis. It implies the loss of tolerance to the inner self, which leads to perturbations in the immune system, with production of autoantibodies. SLE is characterized by multisystem involvement, the evolution of these patients...
Article
Full-text available
Budd-Chiari syndrome (BCS) is a rare disease characterized by obstruction of the hepatic veins, regardless of mechanism and degree, in the absence of heart disease, pericardial disease or sinusoidal obstructive syndrome. In relation to etiology, BCS is classified in primary BCS, when it is caused by an intravascular thrombo- sis, and secondary BCS...
Article
Full-text available
Chronic liver diseases are a public health issue, because of their high incidence and prevalence, the important impact on the quality of life and high mortality rates. From a pathogenic point of view, in almost all liver diseases there is an increase in oxidative stress. Oxidative stress represents as an imbalance between the production of oxidizin...
Article
Pregnancy-specific dermatoses are a heterogeneous group of inflammatory dermatoses associated exclusively with pregnancy. Although these dermatoses are rare, it raises problems in medical practice because of their appearance, being difficult to diagnose, treat and the possibility of the fetus being affected. Pemphigoid Gestationis (PG) is a rare, a...

Network

Cited By

Projects

Project (1)
Project
World-wide interest in the exogenous plant antioxidants was first evoked by the discovery and subsequent isolation of a natural antioxidant compound named ascorbic acid from plants. During last two decades, antioxidant potential of plants has received a great deal of attention as supplementation of exogenous antioxidants has been found to be a promising way of countering the undesirable effects of oxidative stress. Considerable amount of data have been generated on antioxidant properties of plants across the world. The need to find a safe and highly effective cure for various dread diseases remains a major challenge for modern science. Plants have been a source of medicine substances for thousands of years and phytoproducts continue to play an essential role in medicine. The latest trend of returning to the natural sources for health and medicine has created a lot of development in the recovery of antioxidants from plants. The project is aimed to investigate medicinal, aromatic and edible plants for their bioactive phytochemicals and antioxidant potency.