Ghada Khiralla

Arid Lands Agricultural Studies and Research Institute (ALARI)

Acrylamide (ACR) is produced during food processing and has been shown to cause health problems. Selenium, especially in its nanoscale, is an important trace element in human nutrition. Chitosan‐stabilized selenium nanoparticles (Ch‐SeNPs) stability and its protective potential against ACR‐induced injury in rats were evaluated. Ch‐SeNPs displayed h...

The ethanolic extracts of many plants have been used in alternative medicine. The present study aimed at evaluating the antioxidant, cytotoxicity, and anticancer potential of cactus and lupin ethanolic extracts compared to utoral drug (UT) on the colon Caco‐2 cancer cell line. Bioactive components, cytotoxicity of Caco‐2 cell cycle, and gene regula...

Diabetic neuropathy is one of the complications of diabetes. This study investigated the possibility of reducing neuropathy of STZ-induced diabetic rats by Terminalia muelleri extract (TE) and comparing the effect of the extract with the therapeutic effect of pioglitazone (PG) drug. The experimental animals were divided into non-diabetic (normal co...

Dihydrofolate (dihydrofolic acid, vitamin B9) is one of the principle reduced forms of folates, which is converted to tetrahydrofolate by dihydrofolate reductase (DHFR). The aim of the present study was to overproduce total folate by inducing accumulation of dihydrofolate (DHF) due to inhibition of DHFR in a thermosensitive mutant (TS) of Lactobaci...

Alternaria species produce several mycotoxins that are of particular health concern. The natural occurrence of three Alternaria toxins; alternariol (AOH), alternariol methyl ether (AME), and tenuazonic acid (TA) in pomegranate fruit was considered. A. alternata and A. tenuissima were identified by analysis of partial sequence of ITS-region. All stu...

Lactobacillus has a well known positive effect on human health. Therefore, this study aimed at applying the antimicrobial and antibiofilm effects of L. pentosus, L. plantarum and L. pentosus HG against 2 common pathogens, Bacillus cereus (food born pathogen) and Pseudomonas aeruginosa (plant pathogen). All lactic acid bacterial strains were identif...

Lactobacillus has a well known positive effect on human health. Therefore, this study aimed at applying the antimicrobial and antibiofilm effects of L. pentosus, L. plantarum and L. pentosus HG against 2 common pathogens, Bacillus cereus (food born pathogen) and Pseudomonas aeruginosa (plant pathogen). All lactic acid bacterial strains were identif...

The study aimed to isolate and characterize probiotic strains with potential cholesterol degrading activity. Fourteen lactic acid bacteria isolated from lamb meat were screened on mineral salt agar supplemented with 0.2% cholesterol (MSC agar). Cell-free supernatants (CFSs) of these isolates were used as a crude source of extracellular cholesterol...

Microbial biofilms, which characterized by their resistance to the traditional antimicrobials, are considered as a renewable source of contamination by pathogens. As alternative antimicrobial and antibiofilm agent selenium nanoparticles (SeNPs) were biosynthesized by treatment of 1mM SeO2 with the free-cell supernatant of Bacillus licheniformis iso...

The present work aimed to determine the bioactive compounds in two rosemary water extracts (RWE1 and RWE2) and to assess their antimicrobial, anti-adhesive and antibiofilm potentials against the food-related Bacillus and Pseudomonas species at concentrations; 4, 8, 12, 16 and 20 mg mL−1. Phenolic compounds and isoflavones in the RWEs were determine...

Aflatoxins are commonly found in cereals worldwide and bring significant threats to the food industry and animal food production. Among a collection of aflatoxin-degradative endophytic bacteria isolated from grains of corn plant, the strain TUBF1 was selected based on its high-ability to utilize aflatoxin B1 (AFB1) (10 μg/mL) as the sole carbon sou...

Thirty soil-isolates of Streptomyces were analyzed to determine their antagonism against plant-pathogenic fungi including Fusarium oxysporum, Pythium aristosporum, Colletotrichum gossypii, and Rhizoctonia solani. Seven isolates showed antifungal activity against one or more strain of the tested fungi. Based on the 16S rDNA sequence analysis, these...

Functional food or medicinal food is any healthy food claimed to have a health-promoting or disease-preventing property beyond the basic function of supplying nutrients. Three nutritional preparations including wheat powder salt solution (WPSS), milk-wheat solution (MWS), fermented milk (FM) and fermented soymilk (FSM) were evaluated for their anti...

span style="font-family: Times New Roman; font-size: small;"> Functional food or medicinal food is any healthy food claimed to have a health-promoting or disease-preventing property beyond the basic function of supplying nutrients. Three nutritional preparations including wheat powder salt solution (WPSS), milk-wheat solution (MWS), fermented milk...

In recent years, novel insights have been made into the role of probiotics in health and inflammatory bowel disease. In the present study, soymilk was fermented with Lactobacillus casei, L. bulgaricus, Bif. longum as single or mixed starters (1:1:1 v/v). The viable counts in probiotic soymilk were ranged from 7 to 8 log CFU/ml. These probiotic soym...