Gerd J Ridder

Gerd J Ridder
University Medical Center Freiburg · Department of Ear, Nose and Throat Medicine

Prof. Dr. med.

About

209
Publications
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Publications

Publications (209)
Article
The PFAPA syndrome is characterized by a regular appearance of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis and is associated with a distinctive poor general condition of the patients. Since its first description in 1987 the syndrome has usually been described in children. But we here report its diagnosis in three adult pa...
Article
PFAPA syndrome is characterized by periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis. Tonsillectomy and adenotonsillectomy are surgical treatment options for this periodic fever syndrome, the significance of which will be discussed. Between 2004 and 2010 we collected data of 36 patients with the diagnosis of PFAPA syndrome. Dat...
Chapter
Differenzierung nach der Lokalisation zur Fascia pharyngobasilaris:
Chapter
Angeborene kraniofaziale Dysplasie aufgrund von Entwicklungsanomalien der embryonalen Kopfanlage, der ersten beiden Viszeralbögen und der angrenzenden Furchen.
Chapter
Definition Alle bei der Entwicklung und Umbildung des Kiemendarms entstandenen Entwicklungsstörungen
Article
Aberrant internal carotid arteries (ICAs) are not rare anatomic variations. We highlight their relevance and underline the need for a clinical grading system in addition to the currently used anatomic classification. This systematic quality assessment study over 7 years includes 125 adults with 231 aberrant ICAs. Digital imaging data sets were anal...
Article
Central skull base osteomyelitis (SBO) is a life-threatening disease originating from ear and from sinonasal infections. The intention of this study was to evaluate contemporary trends in etiology, diagnosis, management, and outcome of SBO and to draw the clinician's attention on this probably underestimated disease. Over a 6-year period we perform...
Article
Purpose Oral and oropharyngeal tumors are often characterized by a deep submucosal growth pattern under an intact mucous membrane. This is particularly true for lesions of the tongue, and may be associated with relevant difficulties regarding diagnosis and treatment planning. The authors hypothesize that the transoral transmucosal application of co...
Article
Variations in the course of the internal carotid artery are not rare and likely to be a congenital anomaly. The purpose of this study is to highlight the clinical impact of aberrant internal carotid arteries in children for surgical and interventional procedures in the head and neck. Retrospective study of the vessel course in patients under the ag...
Article
Full-text available
Since the widespread availability and use of antibiotics the prevalence of Lemierre syndrome (L.S.) has decreased. It is a well-described entity, consisting of postanginal septicaemia with thrombophlebitis of the internal jugular vein with metastatic infection, most commonly in the lungs. The most common causative agent is a gram-negative, non-spor...
Article
Full-text available
To introduce an approach for the detection of putative genetic host factors that predispose patients to develop head and neck squamous cell carcinomas (HNSCC). HNSCC most often result from the accumulation of somatic gene alterations found in tumor cells. A cancer-predisposing genetic background must be expected in individuals who develop multiple...
Article
The salivary glands are unique in the diversity and complexity of their pathologies. Because fine needle aspiration cytology and frozen section are associated with major diagnostic difficulties, the authors analyzed the use of core needle biopsy (CNB) for the histologic assessment of salivary gland lesions. A systematic observational clinicopatholo...
Article
Full-text available
An otherwise healthy 92-year-old woman was admitted to our department with shortness of breath and dysphagia 10 h after a fall in her bathroom. Medical checkup at another institution had not uncovered the causation of the complaints. Clinical and radiological examinations at our department then revealed an expanding retropharyngeal and prevertebral...
Article
Full-text available
To the Editor: Human bocavirus (HBoV) is a newly described parvovirus for which pathogenic potential has not clearly been elucidated (1). Recent findings suggest that HBoV may establish persistent infection of mucosal lymphocytes or contribute to tonsillar hyperplasia in children (2). In previous reports, we described prolonged HBoV DNA detection i...
Article
The authors report on a fatal case of severe tetanus in a 74-year old woman. Despite comprehensive intensive care management they could not achieve a satisfying control of the autonomic dysfunction caused by tetanus. By now there is no established therapy for the treatment of the autonomic dysfunction. This report demonstrates the dismal prognosis...
Article
Exophthalmus is the leading sign of space-occupying lesions of the orbit. Patients may further present with lid swelling, impaired ocular motility and optic neuropathy including a relative afferent pupillary defect, compressive optic disc edema or optic atrophy. Orbital tumors can be classified into various categories depending on the etiology, as...
Article
Wir berichten über eine 68-jährige Patientin mit einer größenprogredienten Halsschwellung. Die HNO-ärztliche Untersuchung zeigte eine prall-elastische, etwa 4×4cm große Raumforderung nuchal rechts ohne Hautveränderungen. Magnetresonanzangiographisch stellte sich ein scharf abgrenzbarer Tumor mit früharterieller Hyperperfusion dar. Zur histologische...
Article
Our results raise the question as to whether specific patterns of 'germline loss of heterozygosity (LOH)' could contribute to the genetic susceptibility for head and neck squamous cell carcinoma (HNSCC). HNSCC usually occurs in older individuals with a history of smoking. However, about 5% of HNSCC patients have never used tobacco or develop this d...
Article
Exophthalmus is the leading sign of space-occupying lesions of the orbit. Patients may further present with lid swelling, impaired ocular motility and optic neuropathy including a relative afferent pupillary defect, compressive optic disc edema or optic atrophy. Orbital tumors can be classified into various categories depending on the etiology, as...
Article
Tumors of the posterior orbit require different therapeutic modalities, depending on the histological entity. In the orbit all structures are in close relationship and the endocranium is in the direct proximity. This requires profound knowledge of topographic anatomy and high therapeutic precision. The surgical approach to the posterior orbit via a...
Article
Surgical therapy of Graves’ orbitopathy comprises orbital decompression as well as strabismus and lid surgery. The former is primarily carried out during active disease, the latter during inactive disease. Orbital decompression abates increased intraorbital pressure and is thus applicable against dysthyroid optic neuropathy and also reduces exophth...
Article
Zusammenfassung Das Therapiespektrum beim Akustikusneurinom hat sich erweitert und differenziert. Eine Auswertung der internationalen Literatur mittels selektiver PubMed-Recherche zeigt, dass otochirurgische, neurochirurgische und radiotherapeutische Verfahren sowie die Wait-and-Scan-Option nicht nur konkurrieren, sondern auch komplementäre Aspekte...
Article
Treatment strategies for vestibular schwannoma have been extended and become more differentiated. An analysis of the international literature with the help of a PubMed search shows that otological and neurosurgical procedures as well as radiation therapies do not only compete but also complement each other. Standardized protocols for the classifica...
Article
Surgical therapy of Graves' orbitopathy comprises orbital decompression as well as strabismus and lid surgery. The former is primarily carried out during active disease, the latter during inactive disease. Orbital decompression abates increased intraorbital pressure and is thus applicable against dysthyroid optic neuropathy and also reduces exophth...
Article
Chondrosarcomas are rare tumors of the head and neck. Nevertheless, they display the most common non-epithelial malignancy of the larynx. Between 1999 and February 2010 we treated six patients with laryngeal chondrosarcoma. The group included two female and four male patients ranging in age from 54 to 82 years. An 82-year-old female patient died 3...
Article
To analyse the risks and potential complications of cutting needle biopsy (CNB) for head and neck lesions, which have not been fully discussed previously. We performed a systematic clinicopathological quality assessment study of 200 patients with cervicofacial lesions who underwent 444 CNB procedures with a semiautomatic biopsy gun. Adequate target...
Article
In the unusual case of a 68-year-old woman with one-sided painless lateral neck swelling, the ENT examination showed a firm nuchal mass (4 × 4 cm) on the right side with no other pathological findings. Angio-MRI confirmed a solid, sharply demarcated tumor with arterial hyperperfusion. Core needle aspiration biopsy was performed, revealing well-circ...
Article
Full-text available
To evaluate contemporary trends in etiology, diagnosis, management, and outcome of descending necrotizing mediastinitis (DNM) and to draw the clinician's attention on this probably underappreciated disease. An uncommon but one of the most serious forms of mediastinitis is DNM which is caused by downward spread of deep neck infections and arises as...
Article
Malignant lymphoma frequently present with cervical lymph node enlargement. Before adequate therapy can be instituted, appropriate biopsy specimens must enable definite subclassification of the disease. While lymph node extirpation, traditionally considered the gold standard in the diagnostic evaluation of lymphoma, is invasive, diagnoses from fine...
Article
Full-text available
Multiple genes and their variants that lend susceptibility to many diseases will play a major role in clinical routine. Genetics-based cost reduction strategies in diagnostic processes are important in the setting of multiple susceptibility genes for a single disease. Head and neck paraganglioma (HNP) is caused by germline mutations of at least thr...
Article
Introduction: Combined intra- and extradural lesions at the jugular foramen constitute a particular challenge to interdisciplinary surgical therapy. An appropriate approach should contribute to radical tumor resection and the best functional result. Although the pathologies show many variations, the juxtacondylar approach can be applied in many cas...
Article
Die 6 Kiemenbögen sind wesentlich an der Bildung des Halses beteiligt (▸ Kap. 6.1.1, „Pharynx“)
Article
Neck masses are common presentations of cancer and require tissue sampling to establish a diagnosis prior to the institution of adequate therapy. The purpose of this study was to evaluate the specific use and potential advantages of core needle biopsy (CNB) for radiation oncology in the head and neck. We performed a retrospective analysis of 346 CN...
Article
Hintergrund: Invertierte Papillome (IP) sind primär benigne epitheliale sinonasale Neubildungen, welche trotz intensiver Forschung heute nach wie vor ein Thema lebhafter Kontroverse darstellen. Weder ist die Ätiologie dieser Tumoren ausreichend geklärt noch liegen einheitliche Literaturangaben zu Potenzial und Ursachen für maligne Entartung vor. Au...
Article
Inverted papillomas are primarily benign neoplasms that occur in the nasal cavity and paranasal sinuses. Many aspects of sinonasal inverted papillomas are still controversial and active fields of research. Inverted papillomas generate considerable interest because they are locally aggressive, have a propensity to recur and are associated with malig...
Article
Full-text available
Objectives: Malignant bone tumors and fibro-osseous bone lesions of the skull base are uncommon, although fibrous dysplasia in this anatomic location is not a rare condition. In general, fibro-osseous lesions of the skull are often difficult to classify on either clinical presentation, radiological findings, or histological presentation alone. The...
Article
Persistent cervicofacial masses require tissue sampling to guide treatment. While open biopsy is invasive, fine-needle aspiration cytology is insufficient to establish a diagnosis in rare clinical or pathological conditions. The cutting needle biopsy (CNB) is not a widely used technique in the head and neck, and its diagnostic effectiveness in unco...
Article
Background: Lymphadenopathies and unclear masses in the head and neck often require tissue sampling to establish a diagnosis and to guide therapy. Open biopsy and lymph node excision is invasive and may entail general anaesthesia. Fine needle aspiration cytology is minimal-invasive and widely used but includes a high rate of non diagnostic samples...
Article
Objectives To review our experience with head and neck paragangliomas (HNPs) in patients with von Hippel-Lindau disease (VHL). HNPs are rare tumors, 30% of which have been shown to be hereditary neoplasms. Since 2000,4 different paraganglioma syndromes (PGL 1–4) have been described. VHL is characterized by retinal angiomas, haemongioblastomas of th...
Article
Pronounced anatomic variations of the extracranial internal carotid artery (ICA) can be found in 5% to 6% of the general population. An aberrant ICA is at risk of injury during routine pharyngeal procedures if the vessel is placed into close relationship with the pharyngeal wall. The objective was to highlight the impact of parapharyngeal ICA aberr...
Article
Malignant peripheral nerve sheath tumours (MPNSTs) are highly aggressive neoplasms with a marked propensity for local recurrence and metastatic spread. The management of MPNSTs continues to challenge pathologists and surgeons. As MPNSTs of the paranasal sinuses and the skull base are rare, prognostic factors and treatment modalities have not been c...
Article
Early diagnosis and aggressive antimicrobial and surgical treatment are essential to successfully treat extensive cervico-mediastinal abscesses of odontogenic origin. Patient management should be performed by experienced clinicians well trained in managing possible complications. We recommend close clinical and radiological postoperative follow-up...
Article
Because the tongue is an organ known for its excellent blood supply, ischaemic lingual necrosis is extremely rare within clinical everyday life. Acute lingual circulatory disturbances can result from impairment of venous drainage or more often from ischaemic arterial occlusion. Due to permanent function loss of the tongue, apparent lingual necrosis...
Article
Hintergrund: Aufgrund ihrer ausgesprochen guten Blutversorgung gelten ischämische Nekrosen der Zunge als klinische Rarität. Manifeste Zungennekrosen können aber zu schwerer Invalidisierung des Betroffenen führen und stellen für den Kliniker eine diagnostische Herausforderung dar. Als häufigste Ursache einer spontanen lingualen Nekrose gilt eine Vas...
Article
Advanced staged and recurrent head and neck malignancies require histological confirmation before planning further treatment. The purpose of this article is to focus on the clinical usefulness of cutting needle biopsies in the head and neck as a minimal invasive procedure to establish a tissue diagnosis in a palliative setting. A retrospective anal...
Article
Unclear cervicofacial masses are common presentations that often require tissue sampling to guide therapy. While open biopsy is invasive, fine-needle aspiration cytology includes a high rate of nondiagnostic samples. A retrospective analysis on 181 core-needle biopsies in 88 patients was performed to determine the diagnostic efficacy of ultrasound-...
Article
Three of four paraganglioma syndromes (PGLs) have been characterized on a molecular genetic basis. PGL 1 is associated with mutations of the succinate dehydrogenase subunit D (SDHD) gene, PGL 3 is caused by SDHC gene mutations, and PGL 4 is caused by SDHB gene mutations. The objective of this study was to investigate whether PGLs are associated wit...
Article
Full-text available
Total or subtotal laryngectomy performed as surgical treatment of locally advanced laryngeal tumors requires a permanent laryngostomy or tracheostomy, and are both associated with severe and lifelong disability. The hitherto published reconstructive methods for the rehabilitation of patients after subtotal anterior laryngotracheal resection of exte...
Article
Acute tonsillitis is an extremely common infection seen in children and adults. In most cases, the family doctor is initially consulted. Intratonsillar, peritonsillar and retrotonsillar abscesses are frequent complications in the course of tonsillitis. In those cases, oropharyngeal infection may lead to a descending process with consecutive mediast...
Article
Background: Acute tonsillitis is an extremely common infection seen in children and adults. In most cases, the family doctor is initially consulted. Intratonsillar, peritonsillar and retrotonsillar abscesses are frequent complications in the course of tonsillitis. In those cases, oropharyngeal infection may lead to a descending process with consec...
Article
Full-text available
The solitary fibrous tumor (SFT) is a potentially malignant spindle cell neoplasm of mesenchymal origin that was originally described as a thoracic lesion originating from pleural tissue. Recently, numerous extrapleural sites of origin have been described, frequently affecting the head and neck region. The purpose of this article is to focus on a f...
Article
Full-text available
Endolymphatic sac tumours (ELSTs) have been known as an individual tumour entity only since 1984. ELSTs may occur either solitarily and sporadically or as a hereditary manifestation associated with von Hippel-Lindau (VHL) disease. The latter association was first observed in 1992 and confirmed by molecular genetic analysis of the VHL gene. No conse...
Article
The growth of dysontogenetic cysts at the floor of the mouth is considered as a rare condition. Cysts of the floor of the mouth may be differentiated depending on location or on histopathologic-embryological criteria into dermoids, epidermoids and teratomas. We report a case of a large cyst at the floor of the mouth and present the results of clini...
Article
Hintergrund: Dysontogenetische Zysten des Mundbodens zählen zu seltenen Raumforderungen im HNO-Bereich. Mundbodenzysten können einerseits nach ihrer Lage, andererseits nach histopathologisch-embryologischen Kriterien in Dermoid-, Epidermoid- oder Teratoid-Zysten unterschieden werden.Patienten und Methode: Wir stellen klinische Untersuchungsbefunde,...
Article
Primary Ewing sarcoma affecting the skull base in general and the petrous bone in particular is extremely rare with only 4 reports of Ewing sarcoma arising in the petrous temporal bone in the international medical literature. The authors report for the first time a case of a primary Ewing sarcoma of the petrous temporal bone in a 5-month-old nursli...