Georgios Blatsios

• MD, PhD
• Consultant at Innsbruck Medical University

Zusammenfassung In der Behandlung von Aderhautmelanomen wurden in den letzten Jahrzehnten signifikante Fortschritte erzielt. Die lokale Tumorkontrolle kann mit Strahlentherapie je nach Methodik in bis zu 98% der Fälle erreicht werden. Chirurgische Techniken werden zur Behandlung von Strahlenkomplikationen, wie dem sogenannten toxischen Tumorsyndrom...

It is known that the eye's scotopic photodetectors, rhodopsin molecules and their associated phototransduction mechanism leading to light perception, are efficient single photon counters. We here use the photon counting principles of human rod vision to propose a secure quantum biometric identification based on the quantum-statistical properties of...

It is known that the eye's scotopic photodetectors, rhodopsin molecules and their associated phototransduction mechanism leading to light perception, are efficient single photon counters. We here use the photon counting principles of human rod vision to propose a secure quantum biometric identification based on the quantum-statistical properties of...

Zusammenfassung Seit vielen Jahrzehnten hat sich die Strahlentherapie mit ihren unterschiedlichen Modalitaten, die uns heutzutage zur Verfugung stehen, als Goldstandard in der Behandlung von gutartigen wie auch bosartigen Tumoren des Augeninneren erwiesen. Der komplizierte medizinische Entwicklungsweg bis heute umfasst eine Zeitspanne von uber 100...

Purpose of this presentation is not only to describe the various viewing systems, endoillumination possibilities and dyes, but also to give some useful tips on how to practically deal with anterior and posterior segment problems that may interfere with visualisation during vitreoretinal surgery.

Filariasis is endemic in most Mediterranean countries, with Italy presenting the highest incidence. Subconjunctival filariasis has been reported occasionally in several countries, but is considered to be rare in Greece. This is a report of a 50 year-old male farmer of Greek origin who presented at the Department of Ophthalmology at University Hospi...

There are multiple possible intraocular manifestations in patients with systemic neoplasms. At first line there are uveal, retinal and vitreous metastases from carcinomas, melanomas and lymphomas. In patients with von Hippel Lindau syndrome or familiar adenomatous polyposis coli (FAP), Gardner or Turcot syndromes, fundus examinations can help in th...

To develop scleral controlled-release-systems of triamcinolone acetonide (TA) based on biodegradable poly(lactide) (PLA). (1) PLA microspheres containing TA were prepared by a single or double emulsification-solvent evaporation method. Morphology, size, effect of drug input and method of microsphere preparation on drug loading, and in vitro TA rele...

For human trials with retinal prostheses it is mandatory to develop procedures to safely explant and possibly reimplant the devices. This prompted us to investigate in a small exploratory study the safety of repeated transchoroidal implantation and explantation procedures of complex subretinal devices in laboratory animals. Repeated transchoroidal...

The functional results after treatment of uveal melanomas are dependent on their size and location within the eye. Large tumours have an increased ocular morbidity due to the expected radiogenic side-effects, in addition to the ocular burden that results from increased tumour regression and necrosis related deposition of cellular and cytokine by pr...

Proton beam irradiation is a high precision irradiation that is suitable for tumours situated at the vicinity of critical structures which need to be preserved. Choroidal melanomas lying close to the optic nerve and macula fulfil these criteria. These structures can be optimally spared from the irradiation, due to the very steep distal and lateral...

This study set out to document the early electrophysiological and immunohistochemical changes that occur in the retina of experimentally induced diabetic rats. Diabetes was induced in rats by intraperitoneal injection of 60 mg/kg of streptozotocin (STZ). Electroretinogram readings were taken monthly under either short-duration or long-duration stim...

Retinal implants are intended to replace photoreceptors in patients suffering from degenerative retinal diseases such as retinitis pigmentosa. Data show that photodiodes in subretinal implants are not powerful enough to stimulate overlying retinal tissue by simply transforming light energy into electrical energy. Therefore, infrared (IR) irradiatio...

Infrared (IR) irradiation is frequently used in ophthalmological diagnosis and treatment. It has been used to selectively stimulate photodiode-based retinal prostheses to prove their function. Data concerning the natural IR-sensitivity of the retina are contradictory. In our experiments in dark-adapted cats an IR-laser (826 nm) and IR emitting diod...

To investigate the effect of intraocular erucylphosphocholine (ErPC) on the retina, the retinal pigment epithelium (RPE), and the choroid in an in vivo rat model. Adult male Brown Norway rats were injected intravitreally with ErPC dissolved in balanced salt solution (BSS) at a final concentration of 10 or 100 microM with BSS serving as control. Adv...

To determine the annual hospitalization rate and risk factors of eye injuries requiring hospitalization in an area of Greece. Retrospective case analysis of 899 consecutive patients with ocular injury admitted at the Department of Ophthalmology, University Hospital at Patras Medical School, Greece, over a 9-year period. The average annual rate of h...

Mice of the DBA/2J strain spontaneously develop complex ocular abnormalities, including glaucomatous loss of retinal ganglion cells (RGC). In the present study ultrastructural features of retinal neurodegeneration in DBA/2J mice of different age (3, 6, 8 and 11 months) are described. By 3 months, RGC apoptosis characterized by electron-dense kariop...