Georgii Bogdanov

University of California, Irvine | UCI · Chemical and Biomolecular Engineering

In the current research work, unsymmetrical acyl thiourea derivatives, 4-((3-benzoylthioureido)methyl)cyclohexane-1-carboxylic acid (BTCC) and methyl 2-(3-benzoylthioureido)benzoate (MBTB), have been synthesized efficiently. The structures of these crystalline thioureas were unambiguously confirmed by single-crystal diffractional analysis. The crys...

The title compound, C10H10FNO3, also known as [4-((4-fluorophenyl)amino)-4-oxobutanoic acid] (BFAOB), is synthesized efficiently, and its structure is confirmed by the SC-XRD technique, which indicates that two crystallographically different molecules are present in the asymmetric unit. The fluorobenzene ring is oriented at a dihedral angle of 76.0...

The antimalarial drug, pyrimethamine is not used any more for the treatment of malaria due to the resistance phenomenon, though, it can be modified for the potential reuse in medicinal chemistry. The current research article is about the possibility of obtaining novel form of the drug with better drug delivery properties by the preparation of new p...

Pyrimethamine was previously used for malaria treatment. It is not recommended nowadays for this purpose due to the developed drug resistance. In the current research work we are reporting the synthesis of pyrimethamine-based novel organic salt: 2, 4-diamino-5-(4-chlorophenyl)-6-ethylpyrimidin-1-ium 3-carboxybenzoate hydrate (1:1:1) (DECH). The org...

The title compound DBNB, C24H20N2O6, has been crystallized and studied by X-ray diffraction, spectroscopic and computational methods. In the title molecule, which is based on a 1,4-distyryl-2,5-dimethoxybenzene core with p-nitro-substituted terminal benzene rings, the dihedral angle between mean planes of the central fragment and the terminal pheny...

The two isomers 2 0-(4-nitrobenzoyloxy)acetophenone (systematic name: 2-acetylphenyl 4-nitrobenzoate) (I) and 2 0-(2-nitrobenzoyloxy)acetophenone (systematic name: 2-acetylphenyl 2-nitrobenzoate) (II), both C 15 H 11 NO 5 , with para and ortho positions of the nitro substituent have been crystallized and studied. It is evident that the variation in...

The crystallization from different solvents of homologs of 1,3-diethyl-2-thiobarbituric acid and p-dimethylaminobenzene with different length of polymethine bridge between donor and acceptor groups (TB[n]) produced three pairs of polymorphs with number of C=C bonds in the chain n=1, 3 and 5. The homologs with the shortest (one methine unit) π-conju...

The three organic two-photon-absorbing cycloalkanone chromophores 2,4-bis-[4-(diethylamino)benzylidene]cyclobutanone, C 26 H 32 N 2 O (I), 2,5-bis[4-(diethyl-amino)benzylidene]cyclopentanone, C 27 H 34 N 2 O (II), and 2,6-bis[4-(diethyl-amino)benzylidene]cyclohexanone, C 28 H 36 N 2 O (III), were obtained by a reaction between 4-(diethylamino)benza...

The title pull–push chromophores, 2-[4-(dimethylamino)benzylidene]-1 H -indene-1,3(2 H )-dione, C 18 H 15 NO 2 (ID[1]) and ( E )-2-{3-[4-(dimethylamino)phenyl]allylidene}-1 H -indene-1,3(2 H )-dione, C 20 H 17 NO 2 (ID[2]), have donor–π-bridge–acceptor structures. The molecule with the short π-bridge, ID[1], is almost planar while for the molecule...

The title compound, C 4 H 12 N ⁺ ·C 11 H 5 N 4⁻ , contains one tetramethylammonium cation and one 1,1,7,7-tetracyanohepta-2,4,6-trienide anion in the asymmetric unit. The anion is in an all- trans conjugated C=C bonds conformation. Two terminal C(CN) 2 dinitrile moieties are slightly twisted from the polymethine main chain to which they are attache...

Two compounds, 1,3-diethyl-5-{(2 E ,4 E )-6-[( E )-1,3,3-trimethylindolin-2-ylidene]hexa-2,4-dien-1-ylidene}pyrimidine-2,4,6(1 H ,3 H ,5 H )-trione or TMI, C 25 H 29 N 3 O 3 , and 1,3-diethyl-2-sulfanylidene-5-[2-(1,3,3-trimethylindolin-2-ylidene)ethylidene]dihydropyrimidine-4,6(1 H ,5 H )-dione or DTB, C 21 H 25 N 3 O 2 S, have been crystallized a...

The synthesis, crystal structure studies and solvatochromic behavior of 2-{(2E,4E)-5-[4-(di­methyl­amino)­phen­yl]penta-2,4-dien-1-yl­idene}malono­nitrile, C16H15N3 (DCV[3]), and 2-{(2E,4E,6E)-7-[4-(di­methyl­amino)­phen­yl]hepta-2,4,6-trien-1-yl­idene}malono­nitrile, C18H17N3 (DCV[4]), are reported and dis­cussed in comparison with their homologs...

Structural and spectroscopic characteristics of merocyanine dyes are important because of their potential applications in optoelectronics and sensors. Herein we report synthesis, X-ray diffraction characterization of crystal structure, spectroscopic and NMR studies of four merocyanine dyes which, according to their strong donor-acceptor structure,...