
Georgia NtaniUniversity of Southampton · MRC Lifecourse Epidemiology Unit
Georgia Ntani
PhD in medical statistics
About
193
Publications
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Introduction
Skills and Expertise
Publications
Publications (193)
Background and purpose:
Younger recipients of total hip arthroplasty (THA) highly prioritize returning to preoperative levels of physical activity (PA). Surgeons have tended to give cautious advice concerning high-impact sports participation, but there have been few long-term studies. The purpose of our study was to investigate the risk of revisio...
Introduction
With demographic changes, there is increasing demand for individuals and governments to lengthen working lives. Jobs that are very physically demanding are likely to be more difficult to sustain at older ages. If workers at risk of mismatch of demand and capability could be identified early, there would be opportunities for interventio...
Background:
Fatigue is commonly reported in population surveys and has been identified in patients with health conditions as a key co-morbidity which makes remaining in work challenging. Such patients, however, rarely have access to programmes to help them manage their fatigue.
Aims:
To quantify the relationship between fatigue, work impairment...
Background
Knee pain (KP) is common often leading to disability and early workforce exit. In a large group of workers, we examined the prevalence of KP longitudinally, its relationship with pain elsewhere, and personal and occupational effects on pain at follow-up.
Methods
Data from the CUPID study, comprising office workers, nurses and manual wor...
Introduction
COVID-19 severely disrupted healthcare systems. Surgeons are dealing with prolonged waiting-lists, leading them to work longer hours under high stress. We aimed to describe the physical and psychosocial demands on surgeons in the UK, their experience of musculoskeletal pain and their impacts in the post-Covid era.
Methods
UK surgeons...
Introduction
Stammering (stuttering) is a speech disorder with high heterogeneity, characterised by involuntary disrupted speech (dysfluency). We assessed the impact of stammering on work, occupational health (OH) usual care, and assessed the demand for a workplace support intervention.
Methods
Mixed methods.
Results
470 healthcare workers who st...
Introduction
Governments require people to work to older ages. However, evidence shows this might not be feasible for obese people. We explored the association between body mass index (BMI) and health-related job loss (HRJL) in a cohort of older workers in England. We additionally tested whether slow walking speed and depression may explain such as...
Introduction
We explored opportunities, barriers and enablers to growing a multidisciplinary occupational health workforce.
Methods
Mixed methods
Results
30/127 OH departments contributed workforce data. We found wide variation in staff composition and job roles. Nursing and medical staff were the dominant staff groups, with psychologists, physio...
Background
Women increasingly work beyond age 50+ but their occupational health is under-researched.
Aims
To investigate what jobs older contemporary women do, when they exit their jobs and what factors predict job exit.
Methods
Data came from the Health and Employment After Fifty cohort, which recruited women aged 50–64 at baseline in 2013–14 an...
Background
Governments of Western countries need people to work to older ages, however the COVID-19 pandemic impacted the workforce by pushing older adults to retire. Socio-demographic factors that influence the decision to retire in the pre-pandemic period were, poor or good health, finances, marital status, and gender. The aim of this study was t...
Introduction
Musculoskeletal pain is common, often leading to disability and incapacity for work. It frequently occurs at multiple sites of the body resulting in worse health outcomes. We assessed prevalence and work-related effects of multisite musculoskeletal pain among surgeons in the UK.
Methods
Surgeons were approached using societies and soc...
Background
Little is known about ability to work after unicompartmental knee replacement (UKR) and total knee replacement (TKR), especially in physically-demanding occupations. This study described rates of return-to-work (RTW) and ability to sustain work by job after arthroplasty.
Method
Participants from The Clinical Outcomes in Arthroplasty Stu...
The COVID-19 pandemic resulted in a dramatic reduction of routine healthcare availability in many European countries. Among a cohort of English middle-aged adults, we explored pre-pandemic and pandemic factors associated with not seeking healthcare during lockdown, and their effect on subsequent self-reported health measures. Longitudinal data from...
Background
The COVID-19 pandemic markedly disrupted people’s lives. It caused higher mortality and morbidity amongst individuals from poorer socio-economic position (SEP). It is well-recognised that job loss has a negative impact on health. We hypothesised that health effects of the pandemic on middle-aged people might be different depending on SEP...
Background: Governments need people to work to older ages but the prevalence of chronic disease and comorbidity increases with age and impacts work ability.
Aims: To investigate the effects of objective health diagnoses on exit from paid work amongst older workers.
Methods: Health and Employment After Fifty (HEAF) is a population cohort of adults...
Background
Foot and ankle pain (FAP), particularly that of musculoskeletal origin, is increasingly prevalent in our aging populations ¹ . Moreover, governments need people to work to older ages to reduce the costs of pensions and welfare benefits. It is not currently known however whether people with FAP are able to keep working or to what extent i...
Background
We investigated the feasibility of recruiting patients unemployed for more than 3 months with chronic pain using a range of methods in primary care in order to conduct a pilot trial of Individual Placement and Support (IPS) to improve quality of life outcomes for people with chronic pain.
Methods
This research was informed by people wit...
Background:
Multisite musculoskeletal pain is common and disabling. This study aimed to prospectively investigate distribution of musculoskeletal pain anatomically, and explore risk factors for increases/reductions in the number of painful sites.
Methods:
Using data from participants working in 45 occupational groups in 18 countries, we explored...
Background: to assess the feasibility and acceptability of conducting a trial of the clinical and cost-effectiveness of a new case-management intervention to facilitate the return to work of healthcare workers on sick leave with a common mental disorder (CMD).
Methods: a mixed methods feasibility study.
Results: systematic review examined forty...
Objectives
To investigate the rates of return to work and workability among working-age people following total hip arthroplasty (THA).
Methods
Participants from the Geneva Arthroplasty Registry and the Clinical Outcomes for Arthroplasty Study aged 18–64 years when they had primary THA and with at least 5 years’ follow-up were mailed a questionnair...
Background
Stammering (stuttering) is a speech condition with high heterogeneity, affecting approximately 1% of adults. Research shows it can limit career progression, impact job performance and quality of life.
Aims
To assess the psychosocial impact of stammering among healthcare workers and to develop a new workplace support intervention.
Metho...
Background:
Night/shift work may be increasing but there are few data about the prevalence amongst older workers. With governments encouraging people to work to older ages, it is important to know how feasible night/shift work is for them and whether there are any adverse health consequences.
Aims:
Amongst current older workers (aged 50-64 years...
Introduction
People are increasingly encouraged to work to older ages, thus returning to and staying in work is an important outcome for younger arthroplasty recipients.
Objectives
We examined the impact of physically-demanding occupational activities on the risk of leaving a job because of difficulties with the replaced hip.
Methods
A survey was...
Introduction
There is limited evidence on the ability to sustain employment following knee replacement.
Objective
To describe occupational status before and after uni-compartmental (UKR) and total knee replacement (TKR) and to explore work ability after both types of knee arthroplasty.
Methods
This study was set within the longitudinal Clinical O...
Introduction
Styrene is genotoxic, an animal carcinogen, associated with lymphohematopoietic malignancies in humans, and classified as a group 2A carcinogen by the IARC.
Objective
To combine and harmonize existing cohorts of reinforced plastics industry workers with the aim to study exposure-response relations for styrene and subtypes of lymphohem...
Introduction
In the UK, workers who were essential to maintain communications, travel, food and healthcare were deemed ‘key workers’. There is scarce evidence about the effect that the pandemic had on this group of workers as compared with people who were home working, furloughed or retired.
Objectives
To compare measures of health and lifestyle a...
Introduction
Night/shift work is increasing but there are few data about the prevalence amongst older workers. Night/shift work has been associated with a number of adverse physical and mental health outcomes, including cardiovascular disease, cancer, anxiety, and depression. With governments encouraging people to work to older ages, it is importan...
Aim
Generally, good work is good for health but there are few objective data about the effect of permanent exit from work (either through normal retirement, or health-related job exit) on health at older ages. We aimed to explore if exit from the workforce is followed by a change in self-rated health, using longitudinal data from the Health and Emp...
Background: clustering of observations is a common phenomenon in epidemiological and clinical research. Previous studies have highlighted the importance of using multilevel analysis to account for such clustering, but in practice, methods ignoring clustering are often employed. We used simulated data to explore the circumstances in which failure to...
Introduction
Numerous environmental factors within supermarkets can influence the healthfulness of food purchases. This research aims to identify the changes in store healthfulness scores and assess the variations by store type and neighborhood deprivation using an adapted Consumer Nutrition Environment tool.
Methods
Between January and May 2019,...
Background/Aims
Total hip arthroplasty is increasingly offered at younger ages whilst simultaneously people are being encouraged to work to older ages. Ultimately, more people will expect to need to return to work post-THA. We explored the rates of return to work and the trajectories of remaining in work post-THA, with particular attention to the...
Background: loneliness is an important public health issue associated with mortality and morbidity. Often researched amongst older people, less is known about risk factors for loneliness among adults aged 50-64 years who are in work. We investigated (a) if exit from the workforce increases the odds of loneliness; (b) whether adverse psychosocial wo...
Objectives
To describe when patients return to different types of work after elective carpal tunnel release (CTR) surgery and identify the factors associated with the duration of sickness absence.
Design
Multicentre prospective observational cohort study.
Setting and participants
Participants were recruited preoperatively from 16 UK centres and c...
Background:
The NHS is the biggest employer in the UK. Depression and anxiety are common reasons for sickness absence among staff. Evidence suggests that an intervention based on a case management model using a biopsychosocial approach could be cost-effective and lead to earlier return to work for staff with common mental health disorders.
Object...
Background
Chronic pain is a common cause of health-related incapacity for work among people in the UK. Individualised placement and support is a systematic approach to rehabilitation, with emphasis on early supported work placement. It is effective in helping people with severe mental illness to gain employment, but has not been tested for chronic...
Background
Hand dermatitis is highly prevalent among nurses due to their frequent exposure to wet work. Providing cost-effective dermatological health surveillance for this occupational group presents a challenge to health service providers.
Aims
To ascertain the predictive value of nurses’ self-assessment of whether they had current hand dermatit...
Background
Clustering of observations is a common phenomenon in epidemiological and clinical research. Previous studies have highlighted the importance of using multilevel analysis to account for such clustering, but in practice, methods ignoring clustering are often used. We used simulated data to explore the circumstances in which failure to acco...
Introduction
Rapidly increasing population old age dependency ratios create a growing economic imperative for people to work to older ages. However, rates of older worker employment are only increasing slowly. Amongst a cohort of contemporary older workers, we investigated risk factors for health-related job loss (HRJL) over 2 years of follow-up....
BACKGROUND: Chronic pain is a common cause of health-related incapacity for work in the UK. Individualised Placement and Support (IPS) is a systematic approach to rehabilitation with emphasis on early funded work placement. It is effective in helping people with severe mental illness to gain employment but has not been tested for chronic pain.
OBJ...
Objectives:
Health and job satisfaction are key independent determinants of ability to work to older ages. We investigated the interaction of these two important factors on health-related job loss (HRJL) over 2 years of follow-up comparing male and female older workers.
Methods:
A population sample of adults aged 50-64 years, recruited from 24 E...
Background
Musculoskeletal disorders are one of the main causes of sickness absence in the UK and their prevalence is likely to increase in workers, with the rise of state pension age. Previous research has shown that these conditions are common among health and social care workers. Therefore, we aimed to describe the prevalence of musculoskeletal...
Background
Incident chronic widespread pain (CWP) is associated with demographic and personal risk factors such as low mood and somatisation. More recently, there has been increased focus on the role of workplace factors on CWP. However, evidence from studies exploring the interaction of demographic, personal risk factors, job activities and psycho...
Context:
Product placement strategies have been used to influence customers' food purchases in food stores for some time; however, assessment of the evidence that these techniques can limit unhealthy, and promote healthy, food choices has not been completed.
Objective:
This systematic review aimed to determine how product placement strategies, a...
Objectives
To explore the association of sickness absence ascribed to pain at specific anatomical sites with wider propensity to musculoskeletal pain.
Methods
As part of the CUPID (Cultural and Psychosocial Influences on Disability) study, potential risk factors for sickness absence from musculoskeletal pain were determined for 11 922 participants...
Objectives
Three billion people use biomass fuel for cooking and heating globally. We assessed the association between acute coronary syndromes (ACS) and use of biomass fuel for cooking.Methods
We conducted a case–control study among women living in defined areas that were served by two tertiary care hospitals. A total of 364 women admitted to card...
To assist interpretation of a study in rural Pakistan on the use of biomass for cooking and the risk of coronary heart disease, we continuously monitored airborne concentrations of fine particulate matter (PM2.5) and carbon monoxide (CO) for up to 48 h in the kitchens of households randomly selected from the parent study. Satisfactory data on PM2.5...
Background:
Occupational hand dermatitis poses a serious risk for nurses.
Objectives:
To evaluate the clinical and cost-effectiveness of a complex intervention in reducing the prevalence of hand dermatitis in nurses TRIAL DESIGN: Cluster randomised controlled trial at 35 hospital trusts/health boards/universities in the United Kingdom.
Methods:...
Background:
To explore the relationship between radiographic spondylolisthesis and occupational factors in a case-control study nested within the Wakayama Spine Study (WSS).
Methods:
The WSS is a cross-sectional observational study amongst Japanese adults. All participants completed a lifetime occupational history and underwent X-rays of the lum...
Background: To explore the relationship between radiographic spondylolisthesis and occupational factors in a case-control study nested within the Wakayama Spine Study (WSS). Methods: The WSS is a cross-sectional observational study amongst Japanese adults. All participants completed a lifetime occupational history and underwent X-rays of the lumbar...
Background: To explore the relationship between radiographic spondylolisthesis and occupational factors in a case-control study nested within the Wakayama Spine Study (WSS). Methods: The WSS is a cross-sectional observational study amongst Japanese adults. All participants completed a lifetime occupational history and underwent X-rays of the lumbar...
Background: To explore the relationship between radiographic spondylolisthesis and occupational factors in a case-control study nested within the Wakayama Spine Study (WSS). Methods: The WSS is a cross-sectional observational study amongst Japanese adults. All participants completed a lifetime occupational history and underwent X-rays of the lumbar...
Background
Although strategies have been developed to minimise the risk of occupational hand dermatitis in nurses, their clinical effectiveness and cost-effectiveness remain unclear.
Objectives
The Skin Care Intervention in Nurses trial tested the hypothesis that a behaviour change package intervention, coupled with provision of hand moisturisers,...
Background:
Previous research has indicated that wide international variation in the prevalence of disabling low back pain among working populations is largely driven by factors predisposing to musculoskeletal pain more generally. This paper explores whether the same applies to disabling wrist/hand pain (WHP).
Methods:
Using data from the Cultur...
Objectives
To explore the associations of hypertension and coronary heart disease (CHD) with use of biomass fuel for cooking.
Design
Comparative cross-sectional study.
Setting
Rural villages in Sindh, Pakistan.
Participants
Women aged ≥40 years who had used biomass fuel for cooking for at least the last year (n=436), and a comparison group (n=41...
Objective To explore the relationship between radiographic spondylolisthesis and occupational factors in a case-control study nested within the Wakayama Spine Study (WSS). Design The WSS is a cross-sectional observational study amongst Japanese adults. All participants completed a lifetime occupational history and underwent X-rays of the lumbar spi...
Objective
We aimed to assess the safety of opioids in the management of osteoarthritis (OA) in a systematic review and meta-analysis of randomized, placebo-controlled trials.
Methods
A comprehensive literature search was undertaken in the MEDLINE, Cochrane Central Register of Controlled Trials (Ovid CENTRAL), and Scopus electronic databases. Rando...
Objective
Our aim was to assess the safety of cyclooxygenase-2 (COX-2) inhibitors in the management of osteoarthritis (OA) in a systematic review and meta-analysis of randomized, placebo-controlled trials.
Methods
A comprehensive literature search was undertaken in the databases MEDLINE, Cochrane Central Register of Controlled Trials (Ovid CENTRAL...
b>Background
Recent findings indicate that wide international variation in the prevalence of disabling regional musculoskeletal pain among working populations is driven by unidentified factors predisposing to pain at multiple anatomical sites. As a step towards identification of those factors, it would be helpful to know whether the prevalence of...
Background
To explore the association of MRI‐diagnosed severe lumbar spinal stenosis with occupation.
Methods
Occupational data were collected by questionnaire and all participants underwent spine MRI scans using the same protocol. Central lumbar spinal stenosis (LSS) was graded qualitatively. Those with severe LSS (>two‐thirds narrowing) were com...
Background
To improve population diet environmental strategies have been hailed the panacea because they require little agency or investment of personal resources; this contrasts with conventional strategies that rely on individuals to engage high levels of agency and make deliberate choices. There is an immediate need to improve understanding of t...
Background
Recent research has suggested that wide international variation in the prevalence of disabling regional pain among working populations is driven largely by factors predisposing to musculoskeletal pain in general and not specific to individual anatomical sites. We sought to confirm this finding, using data from an independent source.
Met...
BACKGROUND:
A hand photography protocol was needed to ascertain the presence and severity of dermatitis in a trial testing the effectiveness of a behaviour change intervention to prevent hand dermatitis in nurses.
METHODS:
We developed the protocol in 3 stages: (1) we established a procedure for collecting hand photographs; (2) we conducted a step...
There is a limited evidence base from which to derive recommendations for safe and effective return to different types of occupation after carpal tunnel release surgery. The current practice of members of the British Society for Surgery of the Hand and the British Association of Hand Therapists was investigated with a questionnaire. In total, 173 s...
Background
Wide international variation in the prevalence of disabling low back pain (LBP) among working populations is not explained by known risk factors. It would be useful to know whether the drivers of this variation are specific to the spine or factors that predispose to musculoskeletal pain more generally.
Methods
Baseline information abou...
Background
Wide international variation in the prevalence of disabling low back pain (LBP) among working populations is not explained by known risk factors. It would be useful to know whether the drivers of this variation are specific to the spine or factors that predispose to musculoskeletal pain more generally.
Methods
Baseline information about...
Background
A hand photography protocol was needed to ascertain the presence and severity of dermatitis in a trial testing the effectiveness of a behaviour change intervention to prevent hand dermatitis in nurses.
Methods
We developed the protocol in 3 stages: (1) we established a procedure for collecting hand photographs; (2) we conducted a stepwi...
Background
Tables are often overlooked by many readers of papers who tend to focus on the text. Good tables tell much of the story of a paper and give a richer insight into the details of the study participants and the main research findings. Being confident in reading tables and constructing clear tables are important skills for researchers to mas...
There is evidence that food outlet access differs according to level of neighbourhood deprivation but little is known about how individual circumstances affect associations between food outlet access and diet. This study explored the relationship between dietary quality and a measure of overall food environment, representing the balance between hea...