George Stergiou

George Stergiou
National and Kapodistrian University of Athens | uoa · Faculty of Medicine

Publications

Publications (394)
Article
Objectives: Home blood pressure (HBP) monitoring has become a primary method for hypertension diagnosis and management. This analysis aimed to investigate the optimal and minimum schedule for HBP monitoring. Methods: A retrospective analysis of cross-sectional data was performed, which involved HBP and 24-h ambulatory blood pressure (ABP) monito...
Article
Full-text available
Clinically validated, automated arm-cuff blood pressure measuring devices (BPMDs) are recommended for BP measurement. However, most BPMDs available for purchase by consumers globally are not properly validated. This is a problem because non-validated BPMDs are less accurate and precise than validated ones, and therefore if used clinically could lea...
Article
Cuffless blood pressure (BP) measurement has become a popular field due to clinical need and technological opportunity. However, no method has been broadly accepted hitherto. The objective of this review is to accelerate progress in the development and application of cuffless BP measurement methods. We begin by describing the principles of conventi...
Article
Kiosk-type blood pressure (BP) measuring devices developed for public spaces are available in several countries and might be useful in improving hypertension awareness and management. A systematic review of the evidence on their implementation, accuracy, and usefulness was performed. A systematic search of PubMed studies involving kiosk BP measurem...
Article
Blood pressure (BP) variability (BPV) independently predicts adverse outcomes, making it a potential target for treatment. Preliminary data indicate that dihydropyridine calcium channel blockers (CCB) may reduce BPV more than other antihypertensives but data from ad hoc andomised trials are missing. Aim of REVERENT (Reducing blood pressure Variabil...
Article
Blood pressure (BP) variability (BPV) can be assessed with office (OBP), home (HBP), and ambulatory BP (ABP) measurements. In this analysis, BPV indices assessed using all the three methods were compared before and 10 weeks after administering antihypertensive drug treatment. Untreated hypertensives (or treated after washout period) with elevated B...
Article
Blood pressure (BP) variability (BPV) can be assessed using office (OBP), home (HBP) and ambulatory BP (ABP) measurements. In this analysis BPV indices derived using all the three methods were compared before and after 10 weeks of antihypertensive drug treatment. Untreated hypertensives (or treated after washout period) with elevated BPV (systolic...
Article
Studies in adults showed that blood pressure (BP) variability has independent prognostic value for cardiovascular outcome. This study investigated the relationship between office and home BP variability with indices of preclinical target organ damage in young individuals. Healthy individuals aged 6–25 years referred for elevated BP and healthy volu...
Article
Existing evidence shows that increased values of blood pressure variability (BPV) are associated with a higher risk of subclinical organ damage and cardiovascular events, independently of elevated average BP values. We sought to investigate the relation of novel BPV indices with micro- and macrovascular parameters that have not all been previously...
Article
Central aortic blood pressure (BP) has attracted the researchers interest due to its potential to improving cardiovascular risk stratification. We reviewed the published data on central BP in children and adolescents excluding those with chronic heart, lung or kidney disease, congenital anomaly or syndrome, malignancy, and acute illness. A systemat...
Article
In a post-hoc analysis of a multinational, randomized trial, we investigated whether the efficacy and safety of ramipril and nifedipine gastrointestinal therapeutic system (GITS) differed between the Chinese and European patients with hypertension. Previously treated and untreated (2 weeks washout) male and females patients aged 35–75 years with a...
Article
To compare night-time (asleep) blood pressure (BP) evaluated by home monitoring (HBPM) vs. ambulatory monitoring (ABPM) in adolescents and young adults with diabetes type-1 (DM1) and examine their association with indices of preclinical target organ damage (TOD). Individuals aged 12–30 years with DM1 were subjected to 24-hour ABPM (every 20 min, Mi...
Article
Atrial fibrillation (AF) is the most common sustained arrhythmia which often is asymptomatic and undiagnosed. An automated blood pressure (BP) monitor with an algorithm which detects atrial fibrillation with high diagnostic accuracy during routine measurement was used for AF screening in the elderly general population Greece. EMENO health survey (2...
Article
To evaluate the relationship of night-time blood pressure (BP) assessed by home (HBP) or ambulatory BP (ABP) monitoring with preclinical target organ damage in adults with type 2 diabetes (DM2). Hypertensive adults with DM2 or pre-diabetes on stable treatment were subjected to (i) 24 h ABP monitoring (20 min intervals, Microlife WatchBP O3), (ii) H...
Article
To assess the prevalence of white-coat (WCH) and masked (MH) hypertension detected by only ambulatory or only home blood pressure (BP) monitoring (isolated), or both (dual), and their association with preclinical target organ damage (TOD). Young individuals referred for elevated BP and healthy volunteers aged 6–25 years were evaluated with office (...
Article
Home blood pressure (HBP) monitoring has become a primary method for hypertension diagnosis and management. Most hypertension guidelines suggest HBP monitoring for 3–7 days and exclusion of first day for calculation of the average. This analysis investigated the optimal and minimum schedule for HBP monitoring using a European database. A retrospect...
Article
The coronavirus disease 2019 pandemic caused an unprecedented shift from in person care to delivering healthcare remotely. To limit infectious spread, patients and providers rapidly adopted distant evaluation with online or telephone-based diagnosis and management of hypertension. It is likely that virtual care of chronic diseases including hyperte...
Article
Full-text available
Automated ‘oscillometric’ blood pressure (BP) measuring devices (BPMDs) were developed in the 1970s to replace manual auscultatory BP measurement by mercury sphygmomanometer. Automated BPMDs that have passed accuracy testing versus a reference auscultatory sphygmomanometer using a scientifically accepted validation protocol are recommended for clin...
Article
Full-text available
This study aimed to assess the reliability of opportunistic screening programs in estimating the prevalence, treatment, and control rate of hypertension in the general population. Two recent epidemiological surveys obtained data on hypertension in the adult general population in Greece. The EMENO (2013–2016) applied a multi-stage stratified random...
Article
Current hypertension guidelines recommend using the average values of several blood pressure (BP) readings obtained both in and out of the office for the diagnosis and management of hypertension. In-office BP measurement using an upper-arm cuff constitutes the evidence-based reference method for current BP classification and treatment targets. Howe...
Article
Objective: To evaluate the accuracy of the InBody BPBIO210 manual auscultatory mercury-free hybrid blood pressure (BP) measuring device for professional office use in a general population according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI...
Article
The present study compared the blood pressure variability (BPV) among office (OBP), home (HBP), and ambulatory blood pressure (ABP) measurements and assessed their determinants, as well as their agreement in identifying individuals with high BPV. Individuals attending a hypertension clinic had OBP measurements (2–3 visits) and underwent HBP monitor...
Article
Several novel cuffless wearable devices and smartphone applications claiming that they can measure blood pressure (BP) are appearing on the market. These technologies are very attractive and promising, with increasing interest among health care professionals for their potential use. Moreover, they are becoming popular among patients with hypertensi...
Article
The present paper provides an update of previous recommendations on Home Blood Pressure Monitoring from the European Society of Hypertension (ESH) Working Group on Blood Pressure Monitoring and Cardiovascular Variability sequentially published in years 2000, 2008 and 2010. This update has taken into account new evidence in this field, including a r...
Article
Aims: To evaluate whether different hypertension phenotypes, namely, isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH) and systolic/diastolic hypertension (SDH) have a differential outcome effect by clinic and ambulatory blood pressure (BP) measurements. Methods: We prospectively evaluated in 569 never-treated patients...
Article
Background and aims Statin therapy is administered to patients with high cardiovascular risk. These patients are also at risk for severe course of coronavirus disease 2019 (COVID-19). Statins exhibit not only cardioprotective but also immunomodulatory and anti-inflammatory effects. This study performed a systematic review of published evidence rega...
Article
Full-text available
Hypertension remains a major public health issue with inadequate control worldwide. The May Measurement Month (MMM) initiative by the International Society of Hypertension was implemented in Greece in 2019 aiming to raise hypertension awareness and control. Adult volunteers (≥18 years) were recruited through opportunistic screening in five urban ar...
Article
This study aimed to investigate a novel technique for nighttime blood pressure evaluation using a home blood pressure (HBP) monitor in children and adolescents, in terms of association with ambulatory blood pressure (ABP) and preclinical organ damage. Children and adolescents (aged 6–18 years) referred for elevated blood pressure were evaluated wit...
Article
Full-text available
Severe coronavirus disease 2019 (COVID-19) is associated with increased risk of venous thromboembolism events (VTE). This study performed a systematic review in PubMed/EMBASE of studies reporting the prevalence of VTE in patients with COVID-19 who were totally screened/assessed for deep vein thrombosis (DVT) and/or for pulmonary embolism (PE). Amon...
Article
Collaborators: Lucas Aparicio (Argentina), Kei Asayama (Japan), Roland Asmar (France), Grzegorz Bilo (Italy), Jean-Marc Boivin (France), Alejandro de la Sierra (Spain), Eamon Dolan (Ireland), Jan Filipovsky (Czech Republic), Geoffrey Head (Australia), Yutaka Imai (Japan), Kazuomi Kario (Japan), Anastasios Kollias (Greece), Efstathios Manios (Greec...
Article
This study aimed to evaluate the reproducibility of office (OBP), ambulatory (ABP), and home blood pressure (HBP) measurements in children and adolescents, and their implications in diagnosing hypertension in clinical practice and in pediatric hypertension research. Apparently healthy children and adolescents referred for suspected hypertension wer...
Article
Objective: The aim of this study was to evaluate the accuracy of the single upper-arm cuff oscillometric blood pressure (BP) monitor InBody BPBIO750 developed for self-measurement by adults in public spaces (kiosk) according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organizatio...
Article
Full-text available
Background Nationwide data on cardiovascular risk factors prevalence is lacking in Greece. This work presents the findings of the national health examination survey EMENO (2013–2016) regarding the prevalence of hypertension, hypercholesterolemia, diabetes, obesity and smoking. Methods A random sample of adults (≥18 years) was drawn by multistage s...
Article
Full-text available
Objective: The evidence on the epidemiology of hypertension in Greece is limited. The prevalence and control of hypertension was assessed in randomly selected adults of the general population in Greece within the nationwide epidemiological study EMENO. Method: On the basis of 2011 census, EMENO applied a multistage stratified random sampling met...
Article
Objectives: Blood pressure (BP) measurement in atrial fibrillation (AF) patients is problematic and automated monitors are regarded as inaccurate. The optimal procedure for validating BP monitors in AF is questionable. This study evaluated the accuracy of a novel professional oscillometric upper-arm cuff device (Microlife WatchBP Office), which ha...
Article
This study attempted to investigate the behavior of 24‐hour central ambulatory blood pressure (ABP) in adolescents and young adults. Adolescents and young adults (age 10‐25 years) referred for elevated blood pressure (BP) and healthy volunteers had simultaneous 24‐hour peripheral (brachial) and central (aortic) ABP monitoring using the same automat...
Article
Current literature suggests a higher risk of pregnancy-related complications in patients with renal fibromuscular dysplasia (FMD). The aim of our study was to assess the nature and prevalence of pregnancy-related complications in patients subsequently diagnosed with FMD. A call for participation was sent to centers contributing to the European/Inte...
Article
Carotid‐femoral pulse wave velocity (cfPWV) is the gold standard method for assessing arterial stiffness. This study evaluated automated brachial‐ankle PWV (baPWV) taken by a professional oscillometric blood pressure monitor (Microlife WatchBP Office Vascular) versus reference cfPWV (Complior device). Subjects recruited from a hypertension outpatie...
Article
Full-text available
Elevated blood pressure remains the single biggest risk factor contributing to the global burden of disease and mortality. May Measurement Month is an annual global screening campaign aiming to improve awareness of blood pressure at the individual and population level. Adults (≥18 years) recruited through opportunistic sampling were screened at sit...
Article
Full-text available
Elevated blood pressure remains the single biggest risk factor contributing to the global burden of disease and mortality. May Measurement Month is an annual global screening campaign aiming to improve awareness of blood pressure at the individual and population level. Adults (≥18 years) recruited through opportunistic sampling were screened at sit...
Article
Objectives: To investigate the relationship of 24-h ambulatory central blood pressure (ABP) with preclinical organ damage in youth. Methods: Individuals aged 10-25 years referred for suspected hypertension and healthy volunteers had simultaneous 24-h peripheral and central ABP monitoring (Mobil-O-Graph 24 h PWA). Central BP was calculated using...
Article
COVID‐19 is associated with increased risk of venous thromboembolic events (VTE). However, there is significant heterogeneity in the thromboembolic phenotypes of COVID‐19 patients (deep vein thrombosis, pulmonary embolism/thrombosis). The latter might be partly attributed to the variation in VTE risk factors in COVID‐19 patients including: (i) pati...
Article
Elevated blood pressure remains the single biggest risk factor contributing to the global burden of disease and mortality. May Measurement Month is an annual global screening campaign aiming to improve awareness of blood pressure at the individual and population level. Adults ({greater than or equal to}18 years) recruited through opportunistic samp...
Article
Full-text available
Document reviewers: Hind Beheiry (Sudan), Irina Chazova (Russia), Albertino Damasceno (Mozambique), Anna Dominiczak (UK), Anastase Dzudie (Cameroon), Stephen Harrap (Australia), Hiroshi Itoh (Japan), Tazeen Jafar (Singapore), Marc Jaffe (USA), Patricio Jaramillo-Lopez (Colombia), Kazuomi Kario (Japan), Giuseppe Mancia (Italy), Ana Mocumbi (Mozambi...
Article
There is disagreement between the American and the European guidelines for hypertension management in regard to the optimal blood pressure target in patients with chronic kidney disease (CKD). Randomized clinical trials and meta‐analyses of individual patient data pooled from these trials do not clearly support an intensive blood pressure target fo...
Article
Full-text available
Emerging evidence shows that severe coronavirus disease 2019 (COVID‐19) can be complicated with coagulopathy namely disseminated intravascular coagulation, which has a rather pro‐thrombotic character with high risk of venous thromboembolism. The incidence of venous thromboembolism among COVID‐19 patients in Intensive Care Unit appears to be somewha...
Article
Background Pediatric hypertension is typically defined as blood pressure ≥ sex-, age-, and height-specific 95th percentile (high) cutoffs. Given the number of stratum, there are hundreds of cutoffs for defining elevated and high BP that make it cumbersome to use in clinical practice. This study aimed to evaluate the utility of the static cutoffs fo...
Article
Objectives: To compare the association of home (HBP), ambulatory (ABP) and office blood pressure (OBP) measurements with preclinical organ damage in young individuals. Methods: Individuals referred for elevated blood pressure and healthy volunteers aged 6-25 years were evaluated with OBP (2-3 visits), 7-day HBP and 24-h ABP monitoring. Organ dam...
Article
Objective: The current study reviewed the published evidence on the seasonal changes in blood pressure (BP) assessed using different measurement methods. Methods: A systematic PubMed/EMBASE search was performed for studies assessing seasonal BP changes. Prospective and cross-sectional studies were included fulfilling the following criteria: (i)...
Article
: Blood pressure (BP) exhibits seasonal variation with lower levels at higher environmental temperatures and higher at lower temperatures. This is a global phenomenon affecting both sexes, all age groups, normotensive individuals, and hypertensive patients. In treated hypertensive patients it may result in excessive BP decline in summer, or rise in...
Article
Objective: The aim of this study was to evaluate the accuracy of the InBody BPBIO250 oscillometric upper-arm professional office blood pressure (BP) monitor in general population according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO)...
Chapter
Office blood pressure (BP) measurement has been shown to be an unreliable indicator of true BP and although it remains the commonest method of measurement, recent guidelines recommend its use for screening only with diagnostic and management decisions being made with out-of-office measurement techniques, either using 24-h ambulatory BP measurement...
Chapter
Home blood pressure (BP) monitoring is a more accurate diagnostic modality for hypertension than office BP measurement. Nonetheless, home BP measurement (HBPM) must be performed at specific times (morning and evening) under specific conditions (e.g., with the subject at rest), and thus it is of limited use for detecting various forms of masked hype...
Chapter
While home blood pressure (BP) monitoring (HBPM) for hypertension management is recommended by recent guidelines, very few recommendations are provided on the proper choices for devices. In the absence of guidance on how to choose reliable HBPM, the home BP device market has evolved into an uncontrolled one with a majority of devices either not val...
Book
Hypertension remains a leading cause of disability and death worldwide. Self-monitoring of blood pressure by patients at home is currently recommended as a valuable tool for the diagnosis and management of hypertension. Unfortunately, in clinical practice, home blood pressure monitoring is often inadequately implemented, mostly due to the use of in...
Article
Blood pressure (BP) monitors equipped with atrial fibrillation (AF) detection algorithm are attractive screening tools for AF in elderly hypertensives. This study assessed the diagnostic accuracy of a novel cuffless pocket‐size self‐BP monitor (Freescan, Maisense) equipped with an AF detection algorithm, which displays results for the detection of...
Chapter
For more than 30 years, studies highlighting the prognostic accuracy of the self-measured home blood pressure in populations and patients have paved the way for the widespread clinical application of this approach. Blood pressure self-measurement offers several of the well-recognized advantages of the more complex approach of ambulatory blood press...