George Siopis

• BSc Hons MNutrDiet PhD
• Executive Dean Health Research Fellow at Deakin University

Obesity prevalence continues to increase worldwide, with significant associated chronic disease and health cost implications. Among more recent innovations in health service provision is the use of text messaging for health behaviour change interventions including weight management. This review investigates the efficacy of weight management program...

Background/aim There is scarce literature concerning ‘children in need’ at a European level (including Greece), particularly regarding energy balance-related behaviors (EBRBs) associated with overweight and obesity. This scoping review aimed to synthesize evidence on the EBRBs associated with overweight and obesity among ‘children in need’ in Greec...

Machine learning models have the potential to identify cardiovascular diseases (CVDs) early and accurately in primary healthcare settings, which is crucial for delivering timely treatment and management. Although population-based CVD risk models have been used traditionally, these models often do not consider variations in lifestyles, socioeconomic...

Background Diets high in sodium are associated with adverse cardiovascular outcomes. We aimed to quantify the burden of cardiovascular disease (CVD) attributable to high dietary sodium consumption in the Australian population. Methods Using data from the Global Burden of Disease (GBD) 2019, we estimated the age-standardised rates (per 100 000 popu...

Unhealthy diet is associated with increased risk of cardiovascular diseases (CVD). However, there are no studies reporting the impact and trends of dietary risk factors on CVD in Australia. This study aimed to determine the burden of CVDs attributable to dietary risk factors in Australia between 1990 and 2019. We used data from the Global Burden of...

Background: Bangladesh has made substantial progress in improving socioeconomic and health indicators over the past 50 years, but data on national disease burden are scarce. We used data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to estimate the burden of diseases and risk factors in Bangladesh from 1990 to 2019...

This systematic review synthesises the evidence for the effectiveness of a single session of yoga or its components including meditation and breathing techniques in reducing acute stress reactivity in healthy adults. Following the PRISMA guidelines, we searched Medline, EMBASE, Cochrane, CINAHL, and PsycINFO on 30th July 2023 for randomised control...

Digital health interventions have been shown to be clinically-effective for type 2 diabetes mellitus (T2DM) and hypertension prevention and treatment. This study synthesizes and compares the cost-effectiveness of text-messaging, smartphone application, and websites by searching CINAHL, Cochrane Central, Embase, Medline and PsycInfo for full economi...

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, accounting for one-third of global mortality. Prediabetes increases the risk of CVDs as well as several other conditions, yet people with prediabetes may not seek intervention, thinking that they do not have diabetes, as the risk of progression may have not been emphasised by...

The Feel4Diabetes study is a type 2 diabetes prevention program that recruited 12,193 children [age: 8.20 (±1.01) years] and their parents from six European countries. The current work used pre-intervention data collected from 9576 children–parents pairs, to develop a novel family obesity variable and to examine its associations with family sociode...

Background Digital health interventions are effective for hypertension self-management, but a comparison of the effectiveness and implementation of the different modes of interventions is not currently available. This study aimed to compare the effectiveness of SMS, smartphone application, and website interventions on improving blood pressure in ad...

Background Digital health interventions have shown promising results for the management of type 2 diabetes, but a comparison of the effectiveness and implementation of the different modes is not currently available. Therefore, this study aimed to compare the effectiveness of SMS, smartphone application, and website-based interventions on improving...

Aims: To describe morbidity and mortality trends of type 2 diabetes in Australia, from 1990 to 2019, compared with similar sociodemographic index (SDI) countries. Methods: Australia-specific Global Burden of Diseases data were used to estimate age-standardised, age-specific, and sex-specific rates for prevalence, years lived with disability (YLD...

Background: The association between Lynch syndrome (LS) and a higher risk of upper tract urothelial carcinoma is well established, but its effect on the risk of bladder and kidney cancers remains controversial. This review aimed to compare the relative risk (RR) of bladder and kidney cancer in confirmed LS germline mutation carriers compared to th...

Digital health interventions are effective for hypertension self-management, but a comparison of the effectiveness and implementation of the different modes is lacking. This study aimed to compare the effectiveness of short message service (SMS), smartphone application and website interventions on improving blood pressure in people with hypertensio...

Accumulating data emphasize a strong link between obesity and the severity of coronavirus disease-2019 (COVID-19), including mortality. Obesity interferes with several components of the immune system including lymphoid tissue's integrity, leukocytes' development and function, complement system's activation, and the coordination of innate and adapti...

The global population is living longer, however not everyone ages at the same rate in regard to their physical and cognitive abilities and their vulnerability to certain diseases and death. This review aimed to synthesise the contribution of biological age-predictive biomarkers to nutrition research and highlight the implications for future researc...

The Feel4Diabetes study recruited 12,193 children (age: 8.20 ±1.01 years) and their parents from six European countries as part of the broader attempt to prevent type 2 diabetes. The current work collected data pre-intervention to identify the prevalence of childhood obesity by country and describe its association with socio-demographic characteris...

Type 2 diabetes affects an estimated 1.5 million Australians,¹ with a current annual economic burden in excess of $15 billion.² Diabetes prevalence rates follow those of obesity and increase with age,³ predicting further future increases in prevalence considering the continuing rising trend of obesity⁴ and the ever-increasing ageing population.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has to date resulted in more than 200 million cases and more than four million deaths. Following a few months of hiatus, as part of the initial response to the pandemic, professional sporting activities resumed throughout the world. To ensure a safe return-to-play, the effects of SARS-CoV...

Aims This systematic review aimed to evaluate the quality of dietary assessment methods in randomised controlled trials (RCTs) focusing on people with type 2 diabetes (T2DM), and its impact on the favourability of conclusions. Research Methods & Procedures MEDLINE, EMBASE, CINAHL and CENTRAL were searched, from inception until September 2019 for R...

To date more than 100 people over the age of 105 years old have recovered from COVID-19. With age being acknowledged as a major risk factor for morbidity and mortality from COVID-19, this article discusses possible reasons for their survival.

Objectives Diet is critical in diabetes management and new nutritional interventions are continuously being tested in randomized controlled trials. However, to make meaningful conclusions about the efficacy of dietary treatments, it is critical to be certain that the participants adhered to the dietary intervention and the dietary changes are valid...

Nutrition therapy is central to the management of type 2 diabetes and Accredited Practising Dietitians have the expertise to best deliver this type of health care. Yet, some people with type 2 diabetes never consult with a dietitian. This research used a mixed-methods approach to assess the effectiveness of dietetic services and to elucidate the en...

Diet is central to the management of type 2 diabetes (T2D) and better outcomes are achieved when the dietary intervention is delivered by a dietitian. Yet, many people with T2D never see a dietitian. It has been proposed that doctors prefer to provide the dietary advice themselves or rely on medication to treat their patients instead of referring t...

Background Diet is central to treatment of type 2 diabetes. This review aimed to compare the effectiveness of nutrition therapy delivered by dietitians to nutrition advice delivered by other healthcare professionals in adults with type 2 diabetes on metabolic parameters. Methods Cochrane CENTRAL, CINAHL, EMBASE, MEDLINE and PsychINFO were searched...

The coronavirus disease-2019 (COVID-19) pandemic has reportedly resulted in more than one and a half million deaths worldwide. Although it was initially proposed that people of older age and those with certain medical conditions are at higher risk of adverse outcomes, including death, a plethora of people that have markedly surpassed the average li...

Objective To describe the experiences and perspectives of people with type 2 diabetes mellitus (T2DM) regarding dietetic services and to suggest improvements for their access and delivery. Design Semistructured telephone interviews. Setting Urban and rural Australia. Participants A total of 30 English-speaking adults with T2DM recruited by means...

Background The management of diabetes costs in excess of $1.3 trillion per annum worldwide. Diet is central to the management of type 2 diabetes. It is not known whether dietetic intervention is cost effective. This scoping review aimed to map the existing literature concerning the cost effectiveness of medical nutrition therapy provided by dietiti...

Background Diet is central to treatment of type 2 diabetes. This review aimed to compare the effectiveness of nutrition therapy delivered by dietitians to nutrition advice delivered by other healthcare professionals in adults with type 2 diabetes on metabolic parameters. Methods Cochrane CENTRAL, CINAHL, EMBASE, MEDLINE and PsychINFO were searched...

This ePoster was presented in June 2020 at the annual conference of the American Society for Nutrition (ASN), the "Nutrition 2020". Initially planned to take place in Seattle USA, this conference was rendered virtual due to COVID-19, attracting 29,598 registrants from 164 countries.

Objectives Nutrition therapy is crucial for the treatment of type 2 diabetes. Preliminary data indicate that nutrition therapy delivered by accredited dietitians achieves better clinical outcomes than when delivered by other healthcare professionals. We compared dietetic intervention provided by accredited dietitians with nutrition advice provided...

Aims: Dietetic intervention improves glycaemic control of type 2 diabetes mellitus (T2DM). The aim of this study was to explore the views of Australian dietitians with respect to the nutritional management of people with T2DM, patient access to dietitians and any suggested improvements for access to and delivery of dietetic services. Methods: Se...

Aim: Dietetic intervention delivered by Accredited Practising Dietitians is demonstrated to improve clinical outcomes of type 2 diabetes. The aim of the present study was to assess the accessibility to dietetic intervention for people with type 2 diabetes in Australia. Methods: Prevalence data and dietitian workforce distribution data were sourc...

The human PER (hPER) gene reporter constructs were created and the subcellular localization of the various human PER proteins was systematically analyzed, either individually or in all possible combinations, using HuH7 cells (human hepatoma cell line) as an experimental system. It was found that whereas hPER1 and hPER2 can individualy readily trans...