Genís Ona

Genís Ona
International Center for Ethnobotanical Education, Research and Service (ICEERS) | ICEERS · Research

MSc
PhD candidate. Research coordinator at ICEERS

About

46
Publications
29,996
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
235
Citations
Citations since 2016
35 Research Items
228 Citations
2016201720182019202020212022020406080100
2016201720182019202020212022020406080100
2016201720182019202020212022020406080100
2016201720182019202020212022020406080100
Introduction
Currently working in ICEERS as Research Coordinator. PhD candidate in Health, Psychology and Psychiatry at Universitat Rovira i Virgili (URV). Member of the Medical Anthropology Research Center (MARC), URV.
Additional affiliations
January 2021 - June 2021
Institut Botànic de Barcelona
Position
  • PhD Student
Description
  • Doctoral stay in which we assessed the potential use of Cannabis sativa L. for pest control.
May 2018 - October 2021
International Center for Ethnobotanical Education, Research and Service (ICEERS)
International Center for Ethnobotanical Education, Research and Service (ICEERS)
Position
  • Project Manager
Description
  • Community mental health. Global mental health. Epidemiology. Independent research.
April 2018 - September 2018
Centre d'Investigació de Medicaments (HSCSP), Barcelona
Position
  • Internship student
Description
  • Clinical trials. Neurodegenerative diseases. Epigenetic pharmacology. Pharmacology.
Education
September 2017 - September 2018
Autonomous University of Barcelona
Field of study
  • Pharmacology

Publications

Publications (46)
Article
While the field of psychedelic research is continuously expanding and offers new hope for achieving successful treatments for physical and mental disorders, certain methodological aspects require improvement. Some of the flaws are shared with clinical trials for other kinds of drugs and others are specific to the field. Given that psychedelic resea...
Article
Full-text available
The COVID-19 pandemic has made evident the need to develop effective strategies to cushion the psychological consequences of social catastrophes. Preliminary evidence suggests that the use of hallucinogens is a protective factor that mitigates against such stressors. However, the underlying mechanisms must be further explored. This study specifical...
Article
Can the emerging field of psychedelic research benefit from natural product research? We believe it can. In this manuscript we delineate certain topics of research with hallucinogens that directly connect with research on natural products in general.
Article
Full-text available
Context Ibogaine is the main alkaloid of the African shrub Tabernanthe iboga. It produces hallucinogenic and psychostimulant effects, but it is currently known for the anti-addictive properties. Despite the potential therapeutic effects, several cases of fatalities and serious adverse events related to ibogaine/noribogaine use can be found in the l...
Article
Ayahuasca is a plant decoction in traditional Amazonian medicine. Its ritual use has been internationalized, leading to policy challenges that countries should address. This study evaluates the impact of regular ayahuasca ceremony participation on health by assessing the health status of 377 participants in ayahuasca ceremonies in the Netherlands u...
Book
Full-text available
This book describes in an enjoyable, illustrated format the pharmacology of hallucinogenic drugs. Receptors, pharmacokinetics, pharmacodynamics and other complicated concepts are presented in a very informative way.
Article
Objetivos: Caracterizar el estado de salud percibido, la calidad de vida, apoyo social percibido, vida en prisión y uso de cannabis en una muestra de reclusos españoles. Material y método: Se organizó una serie de conversaciones con los reclusos con el objetivo de conocer las motivaciones que les llevaban a consumir cannabis (fase 1). En la fase 2...
Article
Objective: To assess endocannabinoid (anandamide, AEA; 2-arachidonoylglycerol, 2-AG) plasma levels in healthy volunteers and in volunteers with social anxiety disorder (SAD) after a single oral dose of ayahuasca or placebo. Methods: Post hoc analysis of endocannabinoid plasma levels (baseline, 90 and 240 min after drug intake) from two parallel-...
Chapter
Interest in psychoactive ethnobotanicals such as ayahuasca or Psilocybe mushrooms for clinical uses has increased over the last two decades. While clinical and experimental approaches have focused on using isolated compounds of interest (such as psilocybin), an emerging trend in drug discovery involves a more comprehensive approach. The polypharmac...
Article
The Global Mental Health (GMH) movement aims to provide urgently needed treatment to those with mental illness, especially in low-and middle-income countries. Due to the complexity of providing mental health services to people from various cultures, there is much debate among GMH advocates regarding the best way to proceed. While biomedical interve...
Article
Background: Despite the benefits that synthetic pesticides have provided in terms of pest and disease control, they cause serious long-term consequences for both the environment and living organisms. Interest in ecofriendly products has subsequently increased in recent years. Methods: This article briefly analyzes the available ethnobotanical evide...
Article
Full-text available
Background The mechanisms through which kappa opioid receptor (KOR) agonists induce psychotomimetic effects are largely unknown, although the modulation of this receptor has attracted attention for its clinical use. In this work, we characterize the neuropharmacological effects of salvinorin-A, a highly selective KOR agonist. Methods Changes in mu...
Article
Full-text available
Background: One of the main public health strategies adopted at the beginning of the COVID-19 pandemic consisted of implementing strict lockdowns to stop the transmission of the virus. Despite being an effective measure, the confinement and the associated social isolation create a stressful, potentially lengthy situations that has been proven to ha...
Chapter
The volume of research on the therapeutic use of psychedelic drugs has been increasing during the last decades. Partly because of the need of innovative treatments in psychiatry, several studies have assessed the safety and efficacy of drugs like psilocybin or ayahuasca for a wide range of mental disorders, including major depression. The first sec...
Article
Background: In recent decades, ritualistic use of ayahuasca has spread throughout the world. Retrospective studies have suggested a good psychological safety profile, but prospective studies involving ceremony ayahuasca-naive participants are lacking. Methods: We conducted the study using a subsample from a previous study, for which first-time c...
Article
Full-text available
En muchos estudios modernos, así como en sitios web de divulgación o tiendas de productos de cannabis, nos encontramos a menudo con el concepto de "efecto séquito" o entourage effect en inglés. Este se refiere a los efectos sinérgicos que pueden encontrarse en la planta del cannabis y, en general, sirve como pretexto para justificar el uso de extra...
Article
Microdosing psychedelic drugs -that is, taking sub-behavioral doses of lysergic acid diethylamide (LSD) or psilocybin- is a growing practice in Western societies. Taken mainly for creative or mood-enhancing purposes, thousands of users are increasingly being exposed to (micro)doses of psychedelic drugs. In this systematic review, we searched the av...
Article
Research with psychedelic drugs has mainly focused on isolated compounds. However, this approach is challenged by the "polypharmacology" paradigm. In this Viewpoint, we suggest that we may be missing something if we do not use the whole product in the case of ayahuasca or Psilocybe mushrooms. After describing how research on psychedelic drugs can b...
Article
Full-text available
The use of psychedelic drugs for the treatment of some mental disorders is increasing. However, their use is associated to certain risks, being the most important the exacerbation of mental disorders, mainly psychosis or bipolar disorder. While both 3,4-methylenedioxymethamphetamine (MDMA) and psilocybin are on the Phase-III of the process of drug...
Article
Full-text available
The field of psychiatry is facing unprecedented challenges. Despite recent important innovations, several mental disorders continue to lack effective treatment. After briefly exploring some of the current challenges, we suggest that the therapeutic use of psychedelic drugs in psychotherapeutic settings represents a promising and integrative treatme...
Article
Full-text available
Ayahuasca is a hallucinogenic decoction used as a traditional medicine in several Amazonian regions. The ritualistic use of ayahuasca has spread throughout many countries, making it necessary to study its risks and benefits. Two sub-studies were designed for this investigation. In sub-study 1, a psychiatric interview and a battery of questionnaires...
Article
The number of patients using cannabis for therapeutic purposes is growing worldwide. While research regarding the treatment of certain diseases/disorders with cannabis and cannabinoids is also expanding, only a few longitudinal studies have assessed the mid-term impacts of medical cannabis use on psychological variables and quality of life (QoL). T...
Article
In drug development, the creation of highly selective ligands has been unsuccessful for the treatment of central nervous system disorders. Multi-target ligands, from the polypharmacology paradigm, are being proposed as treatments for these complex disorders, since they offer enhanced efficacy and a strong safety profile. Natural products are the be...
Article
In recent years, the use of natural psychoactive drugs (NPDs) has grown rapidly. They are classified as new psychoactive substances (NPSs), despite the reality that they have been used for centuries. We are lacking information regarding patterns of use or characteristics of users, but some evidence suggests that NPDs substantially differ from NPSs...
Article
Full-text available
Background and aims: Pain is the most prevalent symptom of a health condition, and it is inappropriately treated in many cases. Here, we present a case report in which we observe a long-lasting analgesic effect produced by changa, a psychedelic drug that contains the psychoactive N,N-dimethyltryptamine and ground seeds of Peganum harmala, which are...
Article
Assessing the health status of ayahuasca users has been challenging due to the limitations involved in randomized clinical trials and psychometric approaches. The main objective of this study is the implementation of an approach based on public health indicators. We developed a self-administered questionnaire that was administered to long-term ayah...
Preprint
Full-text available
The current crisis in psychopharmacology has a long history and needs to be addressed with innovative and effective strategies. Here we discuss some of the roots of this crisis and suggest that the therapeutic use of psychedelic drugs represents a promising and integrative treatment with enduring effects for mental health problems.
Article
Full-text available
Objetivo. Evaluar el estado de la investigación actual sobre el potencial terapéutico de las sustancias psicodélicas. Metodología. Se realiza una breve revisión temática y se desarrolla un análisis crítico de la situación. Resultados. Se identifican diversas limitaciones y sesgos tanto en estudios observacionales como en ensayos clínicos. Conclusio...
Article
Full-text available
Objective: This study aimed to clarify the influence of extra-pharmacological factors in the etiology of bad trips, a common adverse reaction related to the consumption of psychedelic drugs. Methods: A descriptive approach was adopted. The information was collected using a web-based survey. The survey respondents volunteered to participate based on...
Article
Full-text available
A partir de un análisis de situación, en donde se pone de manifiesto que el tratamiento de la enfermedad mental está sometida a pautas biomédicas, el autor se pronuncia a favor de unas pautas más humanas, que no sigan la tendencia de personificar cosas y reducir los sujetos a cosas.
Article
Full-text available
Introduction: In the past century, many studies suggested that LSD-assisted psychotherapy was effective for a wide range of disorders. Nowadays, there is a comeback of psychedelic research, showing again significant therapeutic potential of hallucinogenic substances. Nevertheless, there is a lack of studies with psychedelic-naïve participants. Perf...
Article
Full-text available
A lo largo de este texto se expondrán distintas corrientes, como el materialismo o el dualismo, discutiendo sus principios en base a los conocimientos o hallazgos que giran en torno a los psicodélicos. En concreto se prestará especial atención a cómo estas corrientes atienden al misterio de la conciencia o al eterno problema mente-cuerpo o mente-ce...
Research
Full-text available
Bibliography of LSD (1952-2015)
Article
Full-text available
El siguiente informe tiene la intención de detallar algunos de los puntos más importantes a tener en cuenta a la hora de cimentar las bases de la aplicación clínica de la psicoterapia asistida con sustancias psicodélicas. Citando los puntos más importantes a tener en cuenta, se propondrá un marco idóneo para el correcto desarrollo de la psicoterapi...
Article
Full-text available
The JTR 7(1) is a Special Issue on Psychedelic Research. Index: Ayahuasca, Contexto Ceremonial y Sujeto: Análisis del Set and Settting a Partir de un Grupo Uruguayo de Terapias Alternativas Ayahuasca, Ceremonial Context and Subject. Analysis of the Set and Setting in an Uruguayan Group of Alternative Therapies Ismael Apud Earth, Gender and Ceremo...
Conference Paper
Results of an observational study with first consumers of LSD
Data
Full-text available
Salvia Divinorum is a perennial herb member of the mint family with psychoactive and dissociative properties. For hundreds of years, it has been used in religious and healing ceremonies by the Mazatec Indians, who live in the province of Oaxaca, in Mexico. Neuropsychological effects of Salvia include alterations of mood, behavior, and cognition. It...
Data
Full-text available
Peyote (Lophophora Williamsii ) is a cactus found primarily in dry regions of Mexico and State of Texas. This cactus contains psychoactive alkaloids, but mescaline is the most important. For its psychedelic effects, the dried tops of the cactus, also known as “buttons”, have been used for centuries by Native Americans in religious ceremonies and fo...
Data
Full-text available
Data
Full-text available

Network

Cited By

Projects

Projects (3)
Project
To study how traditional psychoactive plants such us ayahuasca, iboga/ine or cannabis properly used in contemporary contexts can be of benefit for public health.
Project
Understand the brain mechanisms triggered by the the selective kappa opioid agonist Salvinorin-A
Project
Assess the relationship between psychedelics and mental health.