Geert J.M.G. van der Heijden

• Professor Emeritus
• Retired at Academic Center for Dentistry Amsterdam

Introduction: This study evaluated the Toddler Oral Health Intervention (TOHI) for preventing early childhood caries (ECC) by 48 months. TOHI, an add-on to standard care in well-baby clinics (WBCs), aims to reduce ECC incidence and severity. Methods: Dyads were randomised into TOHI (added to care as usual) or care as usual (CAU). The primary outcom...

Objectives: Periodontitis (PD) patients frequently suffer from comorbidities, necessitating increased attention to disease management and monitoring. The aim of this study is to describe the prevalence and patterns of comorbidities among patients with PD in a private periodontal referral practice. Methods: This study involved 3171 adults with PD. D...

The often poor oral health status of socioeconomically vulnerable adults is widely recognised. Nevertheless, research on it is scarce. To address this gap, this exploratory pilot study aimed to report on the prevalence of untreated caries and its clinical odontogenic consequences, as well as the associated Oral Health Related Quality of Life (OHRQo...

Objective: This research investigated the oral health status of Dutch primary school children aged 10–12 years in Utrecht and its association with demographic characteristics, lifestyle factors, general psychosocial health, and dental treatment, to guide targeted interventions to improve children’s oral and overall well-being. Materials and methods...

Objectives The Toddler Oral Health Intervention (TOHI) was launched in 2017 to promote oral health prevention at well‐baby clinics, with a focus on parents with children aged 6–48 months. This study aims to evaluate the integrity of motivational interviewing (MI) as one of the core intervention pillars in the TOHI study. Methods The TOHI study was...

Aim: To investigate whether and which diseases co-occur with periodontitis (PD) to assess the prevalence of comorbidities and multimorbidity and to identify patterns and profiles of comorbidity and multimorbidity and the influence of demographic and lifestyle factors to identify distinct groups of multimorbid patients. Materials and methods: A d...

The study aimed to assess the prevalence of spin in the titles and abstracts of RCTs in dental caries with statistically nonsignificant primary outcomes and to assess the risk indicators which may be associated with spin. Any original publication reporting a two-arm RCT in dental caries with clearly identified statistically nonsignificant primary o...

In this paper we address the question whether (i) the Dutch dental research portfolio reflects the dental care demand, and whether (ii) the results of this research does reach the dental care professionals. In order to answer these questions, we analyzed the content of the Dutch Journal of Dentistry (NTvT), a Dutch language professional journal whi...

Dit rapport beschrijft het onderzoek naar de groep volwassenen Nederlanders die wegens financiële redenen de mondzorg mijden. Dit onderzoek is in opdracht van de Directie Zorgverzekeringen van het Ministerie van Volksgezondheid, Welzijn en Sport uitgevoerd door medewerkers van ACTA, Radboudumc en Hogeschool van Amsterdam. In dit rapport wordt een...

The current study aimed to explore the types and frequencies of uncommon complications associated with third molar extractions based on a scoping review of case reports and case series. The study used an electronic literature search based on PubMed and Embase up to March 31, 2020, with an update performed on October 22, 2021. Any case reports and c...

The mission of academic excellence has resulted in a science system that incentivises publications within high impact, often basic science journals, and less in application-oriented journals. For the dental research field this so-called academic drift can result in a research portfolio that moves away from research that serves dental healthcare. Th...

Background Early childhood caries is considered one of the most prevalent diseases in childhood, affecting almost half of preschool-age children globally. In the Netherlands, approximately one-third of children aged 5 years already have dental caries, and dental care providers experience problems reaching out to these children. Objective Within th...

Engagement of patients in the composition of a research agenda is essential to reduce the gap between research and practice and thereby generate more impact. The aim of this study was to develop a research agenda for oral health. Experienced challenges and needs with oral health(care) of practitioners and patients formed the input for the research...

There is growing evidence for the beneficial effects of starting oral health prevention early in life. Preventing dental caries in very young children requires considerable investment from parents. Therefore, this cross-sectional study aimed to explore parents’ willingness to pay (WTP) and willingness to invest in time (WTIT) for primary oral healt...

Context A research agenda for oral health care was established in the Netherlands using the Dialogue Model. This project served as a case study in which we applied boundary‐work theory as a framework to understand boundaries (ie demarcations) between and within groups, and how these boundaries can be overcome. Objective To gain insights into the b...

Tooth loss reflects the endpoint of two major dental diseases: dental caries and periodontitis. These comprise 2% of the global burden of human diseases. A lower number of teeth has been associated with various systemic diseases, in particular, atherosclerotic cardiovascular diseases (ACVD). The aim was to summarize the evidence of tooth loss relat...

Objectives: To identify predictors in patient profiles, and to develop, internally validate, and calibrate prediction models for the persistence of self-reported orofacial pain at the 6-month and 12-month follow-up in patients with myofascial pain. Materials and methods: A cohort of 63 adult patients with moderate to severe chronic myofascial pa...

Objectives To assess the predictive performance of caries risk assessment (CRA) models for prediction of caries increment for individuals based on a systematic review and meta-analyses. Data/Sources We included external validation studies assessing the predictive performance of CRA models for prediction of caries increment for individuals, using d...

As the reported data on oral health status among the migrants in Europe is fragmented, we systematically reviewed the published literature on the oral health status, behaviours and care utilisation among migrants residing in Europe. For this, we retrieved publications from PubMed and EMBASE, supplemented by manual citation screening and grey litera...

Introduction Spin is defined as reporting practices that distort the interpretation of results and create misleading conclusions by suggesting more favourable results. Such unjustifiable and misleading misrepresentation may negatively influence the development of further studies, clinical practice and healthcare policies. Spin manifests in various...

Objectives: The aim of this study was to develop a research agenda based on the most important information needs concerning the effects and outcomes of oral healthcare provided by oral healthcare professionals (OHPs). Methods: A two-stage survey study was used to identify and prioritise topics for future research. The first survey generated topi...

Background: In frail older people with natural teeth factors like polypharmacy, reduced salivary flow, a decrease of oral self-care, general healthcare issues, and a decrease in dental care utilization contribute to an increased risk for oral complications. On the other hand, oral morbidity may have a negative impact on frailty. Objective: This...

Objective Undocumented migrants in Europe face multiple barriers in access to oral health care. This study aimed to explore the accessibility of a voluntary dental network providing dental treatments to undocumented migrants in the Netherlands, from the perspectives of patients, dentists and staff members of nongovernmental organizations involved....

Inleiding: Het doel van dit vragenlijstonderzoek was om de attitude, kennis, informatiebehoefte en uitvoe- ring van mondgezondheidsbevordering door jeugd- artsen en jeugdverpleegkundigen op het consultatie- bureau in kaart te brengen. Methode: Tien jeugdgezondheidszorginstanties heb- ben een digitale vragenlijst over kennis, attitude en uitvoering...

Objectives To identify predictors in patient profiles and to develop, internally validate, and calibrate a screening model for diabetes mellitus (DM) in patients with periodontitis in dental settingsMaterials and methodsThe study included 204 adult patients with periodontitis. Patients’ socio-demographic characteristics, general health status, and...

Background: Most randomized controlled trials (RCTs) and meta-analyses of RCTs examine effect modification (also called a subgroup effect or interaction), in which the effect of an intervention varies by another variable (e.g., age or disease severity). Assessing the credibility of an apparent effect modification presents challenges; therefore, we...

Background A proof-of-concept (PoC) study has shown that the ADVOCATE (Added Value for Oral Care) Field Studies approach (academic detailing with feedback data) is considered a feasible, useful and acceptable way to motivate general dental practitioners (GDPs) to reflect on and, if required, change their oral healthcare delivery. The aims of this p...

Objectives To compare international clinical practice guidelines on adult chronic rhinosinusitis (CRS). Design Extensive literature search in Embase, PubMed and the internet (Google, websites of well-known guideline organizations) on November 21st 2018. Main outcome measures Guidelines’ quality was measured by the AGREE II instrument. A summary a...

Background: Academic detailing (AD) is a defined form of educational outreach that can be used to influence decision making and reduce unwarranted variation in healthcare delivery. This paper describes the results of the proof of concept phase of the ADVOCATE Field Studies. This study evaluated the feasibility, acceptability and usefulness of AD re...

Background Feedback information about the quality of oral health care is important for reflective learning by oral health care professionals and the wider health system. To this end, a list of 48 topics describing oral health and oral health care was recently agreed as part of the EU H2020 ADVOCATE project. Objective This article reports on the fo...

Background: Regular inspection of the oral cavity is required for prevention, early diagnosis and risk reduction of oral- and general health-related problems. Assessments to inspect the oral cavity have been designed for non-dental healthcare professionals, like nurses. The purpose of this systematic review was to evaluate the content and the meas...

This study explores associations between frailty and oral health in cross-sectional data of 1,202 community-dwelling older people. Two dichotomous outcomes were used: 1. Potential frailty, using routine primary care data; 2. Self-reported frailty, using a questionnaire. Oral health concerned dental record data and self-reported oral problems. Follo...

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Objective In the last 30 years, innovations in oral healthcare (OHC), such as advanced restorative techniques, shifts towards preventive and evidence-based care and changes in patients’ expectations, have increased the complexity of clinical decision-making in OHC. Little is known about the perspectives of general dental practitioners (GDPs) on the...

Background: Shoulder pain is one of the most common presentations of musculoskeletal pain with a 1-month population prevalence of between 7 and 26%. The overall prognosis of shoulder pain is highly variable with 40% of patients reporting persistent pain 1 year after consulting their primary care clinician. Despite evidence for prognostic value of...

Caries progression seems to follow universal, predictable rates, depending largely on the caries severity in populations: the higher the caries severity, the higher the progression rates. Quantification of these rates would allow prediction of future caries increments. Our aim was to describe caries progression rates in the primary and permanent de...

Background: We wanted to asses and characterize the volume of Otolaryngology publications on clinical research, published in major journals. Methods and Material: To assess volume and study type of clinical research in Otolaryngology we performed a literature search in high impact factor journals. We included 10 high impact factor Otolaryngology jo...

Purpose To assess awareness of, opinion about and adherence to evidence-based guidelines on chronic rhinosinusitis among Dutch Otolaryngologists. Methods We assessed implementation of two guidelines, one Dutch and one European, that are both intended for diagnosis and treatment of patients with chronic rhinosinusitis. We invited 485 Otolaryngologi...

Background: Academic detailing (AD) is a defined form of educational outreach that can be deployed to intrinsically motivate practitioners towards improving quality of care. This paper describes the design of the ADVOCATE Field Studies. This proof of concept study aims to evaluate the feasibility, acceptability and usefulness of AD, reinforced with...

Objectives: The aim was to assess the added diagnostic value of ultrasonography (US) for establishing the presence or absence of disc displacements (DDs) in temporomandibular joints (TMJs). Materials and methods: Pubmed and EMBASE were searched electronically to identify diagnostic accuracy studies that assessed the diagnostic value of US for th...

Purpose: Little is known about psychological factors associated with children's behavior during dental sedation. The purpose of this study was to investigate the associations between parental dental anxiety, coping style, pain catastrophizing (an exaggerated negative response to pain), and children's behavior during dental treatment under moderate...

Aims: To develop models for prognostic prediction of oral health-related quality of life (OHRQoL) for patients with temporomandibular joint osteoarthritis (TMJ OA) at 1- and 6-month follow-ups after arthrocentesis treatment with hyaluronic acid (HA) injections once a week for 4 weeks. Methods: From a cohort of 522 adult patients with TMJ OA trea...

Aims: To identify potential predictors of types of treatment indicated for patients with temporomandibular disorders (TMD) and to develop, validate, and calibrate a prediction model for type of treatment. Methods: The derivation cohort at baseline was comprised of 356 adult patients with TMD. Patient and disease characteristics were recorded at...

In their 2008 series in the BMJ, the GRADE Working Group introduced a binary classification of strength of guideline recommendations - strong or weak - which provided clear direction to clinicians, patients, and policy makers. For clinicians, the implications of a weak (or ‘‘conditional’’) recommendation were very clear: ‘‘you should recognize that...

Background: This study aimed to assess the contribution of material, behavioural, cultural and psychosocial factors in the explanation of socioeconomic inequalities (education and income) in oral health of Dutch adults. Methods: Cross-sectional data from participants (25-75 years of age) of the fifth wave of the GLOBE cohort were used (n = 2812)...

Background High-quality trials have the potential to influence clinical practice. Methods Ten otolaryngology journals with the highest 2011 impact factors were selected and publications from 2010 were extracted. From all medical journals, the 20 highest impact factor journals were selected, and publications related to otolaryngology for 2010 and 2...

Kortekaas MF, Bartelink ME, Zuithoff NP, Van der Heijden GJ, De Wit NJ, Hoes AW. EBM-onderwijs in de praktijk: moeilijker dan gedacht. Huisarts Wet 2017;60(11):551-3. Achtergrond Training in evidence-based medicine (EBM) is een belangrijk onderdeel van de huisartsopleiding. Onderzoek laat zien dat in de klinische praktijk geïntegreerd EBM-onderwijs...

Background It is well known that treatment variation exists in oral healthcare, but the consequences for oral health are unknown as the development of outcome measures is still in its infancy. The aim of this study was to identify and develop outcome measures for oral health and explore their performance using health insurance claims records and cl...

Rationale, aims and objectives Most of the clinical guidelines in low‐resource countries are adaptations from preexisting international guidelines. This adaptation can be problematic when those international guidelines are not based on current evidence or original evidence‐ based international guidelines are not followed. This study aims to evaluat...

The main purpose of this systematic review was to determine the current state of evidence regarding patient satisfaction with, and the impact of, orthognathic surgery on psychosocial functioning of patients 17 yr of age and older. A secondary aim was to determine whether individuals with psychiatric disorders and mental health conditions are more l...

Increasingly more responsive and accountable health care systems are demanded, which is characterized by transparency and explicit demonstration of competence by health care providers and the systems in which they work. This study aimed to establish measures of oral health for transparent and explicit reporting of routine data to facilitate more pa...

Objectives The multi-country-EU project ADVOCATE (Added Value for Oral Care) involves the analysis of routinely collected oral health care records from health insurance systems in six European countries, including NHS England and NHS Scotland. The data will be stored in a in a central repository using AnalytiXagility which adheres to strict privacy...

Objectives Oral diseases are highly prevalent worldwide and their treatment places considerable economic burden on individuals and society. The ADVOCATE (Added value for Oral Care) project aims to promote new, patient-centred preventively oriented primary care and treatment. As part of the project, a benchmarking dashboard is being developed to giv...

Increasingly more responsive and accountable health care systems are demanded, which is characterized by transparency and explicit demonstration of competence by health care providers and the systems in which they work. This study aimed to establish measures of oral health for transparent and explicit reporting of routine data to facilitate more pa...

Supporting info item

Purpose: The purpose of the present systematic review was to assess the added value of panoramic radiography in predicting postoperative injury of the inferior alveolar nerve (IAN) in the decision-making before mandibular third molar (MM3) surgery. Materials and methods: MEDLINE and EMBASE were searched electronically to identify the diagnostic...

The study assessed whether psychological and socio-demographic factors, including somatization, depression, stress, anxiety, daytime sleepiness, optimism, gender and age are associated with pain intensity and pain-related disability in patients with temporomandibular disorders (TMD). In total, 320 TMD patients were involved in the study. The psycho...

In the last 30 years oral healthcare is increasingly being contested. Needs and expectations have evolved to a point of advanced restorative techniques, long term planning for preventative care and evidence-based practice, and patients and payers increasingly require more explicit demonstration of competence. However, relevant data are currently no...

ADVOCATE (Added Value for Oral Care) is a project funded by the European Commission?s Horizon 2020 program, which aims to develop strategies for a system transition toward more patient-centered and prevention-oriented oral health care delivery within health care systems. This system should balance the restorative and preventive approaches in dental...

18 vakinhoud UITGELEZEN NEDERLANDS TANDARTSENBLAD jaargang 71/13, 9 september 2016, www.ntdigitaal.nl NEDERLANDS TANDARTSENBLAD jaargang 71/13, 9 september 2016, www.ntdigitaal.nl Tandartsen zullen steeds opnieuw afwegingen en keuzes moeten maken over de toepassing van nieuwe werkwijzen en technieken. Immers, niet alle innovaties blijken daad-werke...

Rationale, aims and objectives: Most of the clinical guidelines in low-resource countries are adaptations from preexisting international guidelines. This adaptation can be problematic when those international guidelines are not based on current evidence or original evidence-based international guidelines are not followed. This study aims to evalua...

Objectives Evidence-based medicine (EBM) is an important element in the general practice (GP) specialty training. Studies show that integrating EBM training into clinical practice brings larger benefits than stand-alone modules. However, these studies have neither been performed in GP nor assessed EBM behaviour of former trainees in daily clinical...

The multi-country-EU project ADVOCATE (Added Value for Oral Care) strives to optimize the delivery of oral health towards prevention. It involves the analysis of routinely collected oral health care records from health insurances in six European countries, including the National Health Service (NHS) England and NHS Scotland. It is planned to store...

Objective: The multi-country-EU project ADVOCATE (Added Value for Oral Care) involves the analysis of routinely collected oral health care records from health insurance systems in six European countries, including NHS England and NHS Scotland. The data will be stored in a in a central repository using AnalytiXagility which adheres to strict privacy...

Background The association between periodontitis and atherosclerotic cardiovascular diseases (ACVD) has been established in some modestly sized studies (<10 000). Rarely, however, periodontitis has been studied directly; often tooth loss or self-reported periodontitis has been used as a proxy measure for periodontitis. Our aim is to investigate the...

Background: Education in evidence-based medicine (EBM) is an important part of the postgraduate training of GPs. Evaluation of its effect on EBM behaviour in daily clinical practice is difficult and instruments are scarce. Working in accordance with guidelines is considered as one of the key indicators of EBM behaviour. Objective: To develop and...

Background: Otitis media with effusion (OME) is characterised by an accumulation of fluid in the middle ear behind an intact tympanic membrane, without the symptoms or signs of acute infection. Since most cases of OME will resolve spontaneously, only children with persistent middle ear effusion and associated hearing loss potentially require treat...

UITGELEZEN Ongeveer 10 procent van de kinderen onder de vijf jaar lijdt naar schatting aan ernstige cariës (dmft ≥ 6) waarbij pijn, ontstekingen en abcessen serieuze gevolgen voor het dagelijks functioneren kunnen hebben. Ernstige ca-riës kan leiden tot verandering in eetpatroon, leerpro-blemen, schoolabsentie, spraakstoornissen door prema-tuur tan...

Objective: To develop a prognostic model for the thirty-day mortality risk after adult heart transplantation. Methods: In this report we developed a prediction model for the 30-day mortality risk after adult heart transplantation. Logistic regression analysis was used to develop the model in 1,262 adult patients undergoing primary heart transplanta...

The effects of propranolol in the treatment of anxiety disorders have not been systematically evaluated previously. The aim was to conduct a systematic review and meta-analysis of randomised controlled trials, addressing the efficacy of oral propranolol versus placebo or other medication as a treatment for alleviating either state or trait anxiety...

Achtergrond: Complexe gebitten en afname van goede mondhygiëne bij ouderen kan leiden tot een slechte mondgezondheid. Dit kan grote impact hebben op het welzijn en de kwaliteit van leven van ouderen. Met de hogere levensverwachting, zullen de problemen en behoeften betreft mondgezondheid van thuiswonende ouderen de zorgvraag doen vergroten. In dit...

Background: Complex dentitions and decline in adequate oral hygiene in elderly may lead to poor oral health. This may have impact on their general health, wellbeing and quality of life. With increased longevity, the problems and needs in oral health of community dwelling elderly lead to changes in oral health care needs. We identified and prioritiz...

Background: Acute otorrhea is a common problem in children with tympanostomy tubes. We recently demonstrated that treatment with antibiotic-glucocorticoid eardrops is clinically superior to oral antibiotics and initial observation. The aim of this study was to assess the cost-effectiveness of these three common treatment strategies for this condit...

Background The purpose of this study was for us to review diagnostic accuracy of diffusion-weighted imaging (DWI) in primary head and neck squamous cell carcinomas (HNSCCs), detection of metastatic lymph nodes, and recurrences.MethodsA systematic review for studies concerning DWI was performed.ResultsTen studies fulfilled inclusion criteria. All st...

Disease prevention at early ages is a fundamental public health principle and particularly relevant for dental caries, the most common noncommunicable disease (NCD) of humankind. Current oral health promotion is based on the assumption that lower caries levels in childhood continue into later life, and thus preventive use of fluorides must start at...

Background and Objective Current resection modalities for oral squamous cell carcinomas (OSCC) vary from cold steel over CO2 laser to monopolar electro-surgery (MO). We compared thulium laser (TL) as a new modality with MO with regards to pathological assessment.Study Design/Materials and Methods Forty-two patients who were treated for OSCC by eith...

Samenvatting Van Dongen TMA, Van der Heijden GJMG, Venekamp RP, Rovers MM,Schilder AGM. Acuut loopoor bij kinderen met trommelvliesbuisjes. HuisartsWet 2014;57(9):520-3. Achtergrond Het staat niet vast welke behandeling het meest effectief is bij kinderen met trommelvliesbuisjes die een acuut loopoor ontwikkelen: antibiotica(glucocorticoïd)oordrupp...

Objectives/Hypothesis To evaluate the effectiveness of bilateral cochlear implantation over unilateral implantation in children with sensorineural hearing loss. Data Sources Pubmed, Embase, and Web of Science. Review Methods All studies comparing a bilateral cochlear implant group with a unilateral implant group were included. Results Twenty‐one...

Samenvatting Bruins Slot MH, Rutten FH, Van der Heijden GJ, Doevendans PA, Mast EG, Bredero AC, Van der Spoel OP, Glatz JF, Hoes AW. De H-FABP-sneltest bij verdenking op acuut coronair syndroom. Huisarts Wet 2014;57(7):338-41. Achtergrond Biomarkers voor cardiale necrose en ischemie kunnen de vroege diagnostiek van het acuut coronair syndroom (ACS)...