Ged Avery

• Hull and East Yorkshire Hospitals NHS Trust

Background Clinical prediction rules (CPRs) developed to predict adverse outcomes of suspected pulmonary embolism (PE) and facilitate outpatient management have limitations in discriminating outcomes for ambulatory cancer patients with unsuspected PE (UPE). The HULL Score CPR uses a 5-point scoring system incorporating performance status (PS) and s...

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Objectives The aim of this study was to investigate via computer simulation a proposed improvement to clinical practice by deriving an optimised tube voltage (kVp) range for digital radiography (DR) chest imaging. Methods A digitally reconstructed radiograph algorithm was used which was capable of simulating DR chest radiographs containing clinica...

[This corrects the article DOI: 10.1186/s12959-017-0157-x.].

Background An incidental/unsuspected diagnosis of pulmonary embolism (IPE) in cancer patients is a frequent occurrence. This single-institution analysis of uniformly managed patients investigates short and long-term outcomes and proposes a prognostic risk score, aiming to assist clinical decision-making. Methods Data from a prospectively recorded...

A proportion of people living with common variable immunodeficiency disorders develop granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a consensus statement on the definition, diagnosis, and management of GLILD. All UK specialist centers were contacted and relevant physicians were invited to take part in a 3-round on...

J Allergy Clin Immunol Pract. 2017 Jul - Aug;5(4):938-945. doi: 10.1016/j.jaip.2017.01.021. Epub 2017 Mar 25. British Lung Foundation/United Kingdom Primary Immunodeficiency Network Consensus Statement on the Definition, Diagnosis, and Management of Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency Disorders....

Background Idiopathic pulmonary fibrosis (IPF) has a variable disease course and we lack biomarkers that accurately predict prognosis or treatment response. Positron Emission Tomography-Computed Tomography (PET-CT) provides structural and functional information about the lung. A study of 25 IPF patients reported increased 18[F]-FDG uptake in areas...

The use of three physical image quality metrics, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and mean effective noise equivalent quanta (eNEQm) have recently been examined by our group for their appropriateness in the calibration of an automatic exposure control (AEC) device for chest radiography with an Agfa computed radiography (CR...

O1 Tumour heterogeneity: what does it mean? Dow-Mu Koh O2 Skeletal sequelae in adult survivors of childhood cancer Sue Creviston Kaste O3 Locoregional effects of breast cancer treatment Sarah J Vinnicombe O4 Imaging of cancer therapy-induced CNS toxicity Giovanni Morana, Andrea Rossi O5 Screening for lung cancer Christian J. Herold O6Risk stratific...

Malignant mesothelioma is an aggressive form of cancer affecting the pleura and the serous membranes. Asbestos exposure has been shown to be the most important factor contributing to the development of malignant mesothelioma. The current guidelines suggest that investigations and management of patients with mesothelioma require multidisciplinary te...

Objective: The aim of this study was to investigate via simulation a proposed change to clinical practice for chest radiography. The validity of using a scatter rejection grid across the diagnostic energy range (60-125 kVp), in conjunction with appropriate tube current-time product (mAs) for imaging with a computed radiography (CR) system was inve...

The purpose of this study was to examine the use of three physical image quality metrics in the calibration of an automatic exposure control (AEC) device for chest radiography with a computed radiography (CR) imaging system. The metrics assessed were signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and mean effective noise equivalent quan...

Diaphragmatic hernias that are diagnosed in adulthood may be traumatic or congenital in nature. Therefore, respiratory specialists need to be aware of the presentation of patients with these conditions. In this report, we describe a case series of patients with congenital and traumatic diaphragmatic hernias and highlight a varied range of their pre...

Most patients with pulmonary embolism (PE) spend 5--7 days in hospital even though only 4.5% will develop serious complications during this time. In particular, the group of patients with incidentally diagnosed PE (i-PE) includes many patients with low risk features potentially ideal for outpatient management; however the evidence for their optimal...

Background: Pulmonary embolism (PE) is increasingly identified in cancer patients who undergo CT imaging in the absence of clinical suspicion. The morbidity potential of such findings is significant, hence prompt identification and treatment with anticoagulants is warranted. Nevertheless some pulmonary thrombi may remain inconsequential or just cli...

Dermatomyositis associated with lung cancer is uncommon. Dermatomyositis associated with small cell lung cancer is very rare and carries a poor prognosis. We present a case of a patient with dermatomyositis associated with small cell carcinoma of the lung and review the literature.

Dermatomyositis associated with lung cancer is uncommon. Dermatomyositis associated with small cell lung cancer is very rare and carries a poor prognosis. We present a case of a patient with dermatomyositis associated with small cell carcinoma of the lung and review the literature.

vein obstruction or thoracic inlet syndrome (TIS) was made. The patient denied neck or arm pain, numbness, or tingling. In this case, the patient’s presentation was incidental to the diagnosis of TIS and she responded well to steroid replacement for acute adrenal insuffi ciency on a background of Addison’s disease. Twelve months following the initi...

The purpose of this study was to derive an optimum radiographic technique for computed radiography (CR) chest imaging using a digitally reconstructed radiograph computer simulator. The simulator is capable of producing CR chest radiographs of adults with various tube potentials, receptor doses and scatter rejection. Four experienced image evaluator...

Gastric neuromodulation (GNM) has been advocated for the treatment of drug refractory gastroparesis or persistent nausea and vomiting in the absence of a mechanical bowel obstruction. There is, however, little in the way of objective data to support its use, particularly with regards to its effects on gastric emptying. Six patients (male-to-female...

A 62-year-old man presented with chronic dry cough. He was known to have Crohn's disease which was in remission. A plain chest radiograph demonstrated bilateral apical infiltrates. A HRCT of the chest showed normal proximal airways. Stenosis of medium size airways was present with post-stenotic dilation. These dilated peripheral bronchi appeared fl...

The clinical assessment of position in colon and hence completion during flexible sigmoidoscopy (FS) is believed to be inaccurate. The technique of applying endomucosal clips with follow-up X-ray has previously been used for establishing completion in colonoscopy. Furthermore, we have now trained non-healthcare professionals (non-medical endoscopis...

Quality assurance in colonoscopy is important, and subjective assessment of completion based on endoscopic signs can be inaccurate leading to missed lesions. We aimed to determine the technique of endomucosal clips with follow-up X-rays in objectively documenting completion and correlation with pathology miss rates. A total of 82 patients undergoin...

Virtual colonoscopy (VC)/CT colonography has advantages over the well-documented limitations of colonoscopy/barium enema. This prospective blinded investigative comparison trial aimed to evaluate the ability of VC to assess the large bowel, compared to conventional colonoscopy (CC), in patients at high risk of colorectal cancer (CRC). We studied 15...

LEARNING OBJECTIVES To demonstrate the range of HRCT appearances of pleuropulmonary manifestations of rheumatoid disease ABSTRACT The majority of patients with rheumatoid arthritis have extraarticular disorders, a large number having pleural and pulmonary involvement. The spectrum of pulmonary changes ranges from pleural effusions, through interst...

LEARNING OBJECTIVES 1. Multimodality radiological review of extraarticular manifestations of rheumatoid arthritis 2. Role of imaging in identifying extraarticular manifestations of rheumatoid arthritis ABSTRACT Rheumatoid arthritis is a systemic inflammatory disease of unknown aetiology. It is a chronic debilitating illness which affects 1% of the...

Whilst nebulisers are commonly used in the treatment of cystic fibrosis (CF), nebulised aerosol lung deposition in individual patients is not routinely assessed in clinical practice. The present study was designed to evaluate whether a comparative measurement of aerosol lung deposition from nebulisers using a widely available scintigraphic method c...

CTPA is being used more frequently for the diagnosis of PE. Studies carried out have usually compared the procedure with other investigations. We wished to investigate the procedure in terms of patient outcome. Methods: We studied 132 consecutive CTPA procedures over a 15 month period and followed up the patients for 3 to 18 months. The findings of...

The search for liver metastases before surgery forms an accepted part of colorectal cancer surgical practice. Intraoperative ultrasound and manual palpation of liver together form the criterion standard as far as screening for metastases is concerned. However, extracorporeal imaging, such as ultrasound and magnetic resonance imaging, are also widel...

Patients went for immediate AXR and a blinded radiologist commented on the location of the clip aided by the persistent air pneumocolon. Results: 50 patients have been studied to date. Clip application took a median of 4 (2-12) minutes. In 90% (45) of patients the radiologist and the endoscopist agreed that the clip had been placed in the caecum. I...

We report the use of a new flexible-tipped laparoscopic ultrasound transducer during laparoscopic colorectal surgery. The flexible tip, in combination with ‘picture on picture’ videomonitoring, facilitates efficient hepatic assessment. Our early experience suggests that this technique may identify metastases not detected by conventional imaging mod...

Without Abstract

A 67-year-old man developed intrasplenic mycotic aneurysms secondary to bacterial endocarditis. The computed tomography (CT) appearances showing enhancing lesions within the spleen are correlated with the angiographic appearances.

Patients with a testicular mass are usually investigated by ultrasound and the ultrasound appearances have been correlated with the histology. The authors describe two patients with Leydig cell tumours. The first had bilateral tumours which although histologically typical of Leydig cell tumours, had differing ultrasound appearances, one with a prev...

A 71-year-old man presented with signs of a left psoas lesion 4 years after a sigmoid colectomy for adenocarcinoma. Radiological appearances were thought to be typical of an abscess, but an attempted aspiration was unsuccessful. A biopsy was taken and histology showed metastatic adenocarcinoma.

A 71-year-old man presented with signs of a left psoas lesion 4 years after a sigmoid colectomy for adenocarcinoma. Radiological appearances were thought to be typical of an abscess, but an attempted aspiration was unsuccessful. A biopsy was taken and histology showed metastatic adenocarcinoma.

PURPOSE/AIM 1.To define the Nomenclature and review the Pathophysiology of Pneumocystis Pneumonia (PCP). 2.To demonstrate the range of common and uncommon HRCT findings in PCP. 3.To discuss the differential diagnosis. CONTENT ORGANIZATION 1.Pathophysiology and Nomenclature 2.Illustrate the HRCT findings: Common appearances – extensive patchy groun...