GBENOU Joachim Djimon

• University of Abomey-Calavi

Sclerocarya birrea (A. Rich) Hoscht is often used in traditional African medicine in the treatment of much pathology. The aim of this work was to highlight the haemostatic and anti-inflammatory properties from the hydro-ethanolic extract of the trunk bark of Sclerocarya birrea (A. Rich) Hoscht. The in-vitro test of hemostatic activity was carried o...

The application of computational studies is crucial in optimizing the potential of prospective drug candidates by predicting their most important reactive properties. This approach not only reduces experimental costs but also provides precise methods for experimental achievements. It should be noted that the biological activity and toxicity of a dr...

The coagulation is essential in raw water treatment. The most used coagulants are often of chemical origin and expensive and their use generates non-biodegradable residues. This is why innovative studies on the synthesis of natural coagulants based on plant extracts are very important. This study presents a new method of producing a coagulant for t...

Introduction: Low back pain is often intense pain in the lumbar vertebrae of the lower back. It has a wide variety of causes and can have serious consequences. Objective: The aim of this intervention study was to evaluate the cumulative effects of massage and physical exercise on low back pain in women in the city of Yaoundé. Methods: Thirty (30) w...

Diabetes is a major public health problem, due to its high and growing prevalence on the one hand, and its socio-economic impact on the other. Correcting this disease relies on glycemic control, particularly through medication. The majority of African populations are attached to the use of traditional herbal treatments, due to the high cost of mode...

Background: Combretum glutinosum is a plant whose leaves are consumed as a vegetable and used in traditional medicine for the treatment of microbial infections. Objective: The present study was designed to identify the compounds in C. glutinosum leaves extracts, and evaluate its antimicrobial activity, antioxidant ability and its toxicity in Artemi...

Nowadays, theoretical chemistry has experienced a great advance in the search for drugs for the treatment of various human and animal pathologies. Although it is expected that medicinal plants constitute a great source for the research of compounds, the present study has been carried out to provide a list of important plants that can be explored in...

Medicinal plants attract the attention of many researchers to find natural and safe remedies for various resistant diseases. Leaves of Mitragyna inermis are widely used in traditional veterinary medicine for the treatment of gastrointestinal strongyles of small ruminants. The aim of the current study is to estimate the antioxidant, anthelmintic and...

RESUME Les troubles musculo-squelettiques (TMS) constituent la première cause de morbidité liée au travail et occupent la première place des maladies professionnelles. L'objectif de cette étude était d'évaluer la prévalence des TMS chez les conducteurs de motos taxis à Yaoundé. Une étude transversale, descriptive et analytique a été conduite auprès...

The WHO Benin 2021 report clearly indicates that hepatitis B and C kill as much, or more than HIV/AIDS or malaria in Benin. Liver diseases are characterized by inflammation, and in Benin, the leaves of the Lophira lanceolata Van Tiegh. Ex Keay plant are extensively utilized for treating such conditions. This study aims to demonstrate the anti-infla...

Hemorrhoidal disease is a very present ailment that manifests itself in our societies and sometimes leads to cases of surgery. The traditional treatment in Benin is based on the use of medicinal plants. Calotropis procera (Ait.) and Ficus umbellata (Vahl.) are two plants well known in West Africa, precisely in Benin. They are among the most used p...

Turmeric (Curcuma longa L.), a plant native to Asia, was the subject of the present study whose objective was to evaluate the antioxidant properties of the rhizome powder of this plant cultivated at Bopa, a commune of Benin. The methodology used consists in evaluating the toxicity of the extracts by the shrimp larvae, to make the phytochemical anal...

Chromolaena odorata (L.) King and Robinson (Asteraceae) is a tropical shrub with interesting chemical potential widely used in agriculture and medical science and which can be affected by several geographic and climatic conditions. Therefore, we investigated the phytochemical composition of this plant across climatic zones in Benin. The plant mater...

In the Republic of Benin, several plants, including Zea mays Linn (Z. mays) are used for the treatment of diabetes without any scientific studies showing their effectiveness. The objective of this study is to investigate the effects of Z. mays leaves’ extracts on hyperglycaemic rabbits using the Oral Glucose Tolerance Test (OGTT), 2 g/kg of (D) + g...

Essential oils (EO) of aromatic plants have always been used by humans for healing, perfume or food. But an oil using does not always give desired results. Faced with this difference in results, it would therefore be advisable to control the chemical composition in order to optimize the biological activity of each EO. This work is interested in the...

Medicinal plants are endowed important pharmacological properties. Through their broad spectrum of biological activities, people use them for their primary health needs. Uncontrolled use can cause complications for these users. Thus, a study of the antimicrobial activities of pathogenic bacteria in humans would help to elucidate in part the field o...

The uncontrolled use of antimicrobials leads to an increase in the resistance of bacteria which becomes a public health problem. To overcome this problem, our study aims to establish a link between chemical composition and antimicrobial activity and then evaluate cytotoxicity, of seven essential oils. Antimicrobial activity of essential oils was as...

The present study aims to evaluate the anti-diarrhoeal activity of extracts of Mangifera indica leaves, a plant used in traditional medicine for its antimicrobial properties. Thus, the extracts were tested on 10 reference strains and 9 clinical strains isolated from diarrhoeal stools by agar diffusion method and determination of the antimicrobial c...

Introduction: The presence of microbes in our environment is always a permanent public health problem. In this context, research on natural treatment, less expensive and accessible to fight these microbial germs would be beneficial. Methods: During this work, molecules of thiosemicarbazones due to their numerous biological activities were hemi-synt...

Diarrhoea is a microbial disease that causes several million deaths each year in the world, especially in developing countries. In recent years, there has been a renewed interest in medicinal plants, with a multitude of studies conducted by researchers. To allow a rational exploitation of the conclusions of the various works, a meticulous inventory...

Aims: The aim of this study is to develop and validate an efficient method for the specific determination of L-ascorbic acid in citrus fruits and to compare it with a usual method, method using 2,6-dichlorophenolindophenol Methodology: The research for a specific method for determination of L-ascorbic acid has led to development and validation of H...

Effet in vitrod’extraits taniques de Mitragynainermis(Willd.) Kuntze(Rubiaceae) et de CombretumglutinosumPerr. ex DC (Combretaceae) sur le développement des larves de HaemonchuscontortusRudolphi(Trichostrongylidae)chez les ovins.

Combretum glutinosum and Mitragyna inermis are two plants used in Benin as a dewormer and antibiotic in traditional human and veterinary medicine. This study aimed to evaluate the anthelmintic, antimicrobial and antioxidant activities of the both plants tannin extracts. The extracts were tested in vitro on Haemonchus contortus larvae and worms and...

Aims: The leafy stem and fruit of P.murex have been reported to be used in folk medicine to treat male reproductive system ailments. This study was undertaken to assess the antioxidant potential of the aqueous extracts of P.murex leafy stem and fruit. Original Research Article Dossou-Agoin et al.; EJMP, 32(8): 1-9, 2021; Article no.EJMP.71461 2 Met...

Vignacomosa Baker (V. Comosa) is a plant used by Beninese Oueme department’s populationfor the treatment of diabetes without any scientific study showing its effectiveness. The objective of this study is to investigate the effects of theextracts of V. Comosaon hyperglycemic rabbits by Oral Glucose Tolerance Test (OGTT) and on hepatic glucose libera...

A chemical study of the hydro-ethanol extract of the leaves of Combretum glutinosum resulted in the isolation of nine com­pounds, including 5-de­methyl­sin­en­se­tin (1), umuhengerin (2), (20S,24R)-ocotillone (3), lupeol (4), β-sitosterol (5), oleanolic acid (6), betulinic acid (7), corymbosin (8) and β-sito­sterol glucoside (9). Four com­pounds ha...

A comparative study of the major compounds was carried out despite the great diversity of the constituents characteristic of the essential oil of Lippia multiflora. It was interested to note the imprint that makes each locality with the chemical characters of the gasoline. The variation in the chemical composition of essential oils, was depended on...

The objective was to study the antihypertensive effects of the aqueous decoctycrude of Lippia multiflora from the region of Djidja at a dose of the plant as well as the effects of this extract on some biochemical parameters in the rat were made hypertensive by 500 mg/kg of body weight during the 14 days and were treated with losartan potassium at a...

Pleiocarpa pycnantha belong to the family Apocynaceae which is widely distributed throughout tropical Africa. It has an impressive range of medicinal uses. Different parts of this plant contain families of compounds such asalkaloids, Terpenoids, Saponins. The P. pycnantha plant provides actives compounds likeursolic acid, 27-p-E-coumaroloxyursolic...

Trichostrongylus colubriformis is one of the major parasites that hampers the development of small ruminant breeding in West Africa and particularly in Benin. This parasite is a zoonosis that could infest humans if hygiene measures are not taken in pastures. The aim of the present study is to evaluate in vitro, the effect of the aqueous triturated...

The considerable number of secondary metabolites found in a plant gives it several biological properties in traditional medicine. Thus, Combretum glutinosum, is a plant of the Combretaceae family which is known to be used in the treatment of several diseases. This plant has been the subject of several scientific studies that have shown not only tha...

Medicinal plants used by populations are harvested in the environment subjected to contamination by pollutants including heavy metals, toxic to humans. The objective of this research is to assess contamination of 5 medicinal plants commonly used in Benin by mercury and growing sometimes in areas at risk of mercuric contamination. Material plant stu...

Annona muricata Linn commonly called corossol in BENIN is a plant of the family of Annonacceae known throughout the world through its virtues in traditional medicine. This study aimed to compare the phytochemical composition and the antioxidant activity between ethanolic, hydro-ethanolic, and aqueous extracts of Annona muricata leaves collected in...

Cassytha filiformis L., plant with several therapeutic virtues (purgative, hemorrhoid, ulcer, gonorrhea ..), is also used in the treatment of liver diseases. Hepatic diseases are diseases related to oxidative stress. The treatment of liver diseases requires therefore the intake of antioxidant substances. The aim of this work is to prove the antioxi...

Pancratium trianthum Herb. is a herb whose leaves and seeds are reportedly highly toxic. However, the bulb is used in the form of aqueous decoctions, orally, in the treatment of cough and asthma in traditional medicine in southern Benin. The interest in the use of Pancratium trianthum Herb. bulb requires that an approach of its toxicity be undertak...

The objective of this study is to assess the combined effects of exercise and consumption of Cymbopogon citratus on anthropometric and hemodynamic parameters in obese women. Forty (40) obese women were divided into four groups: group 1 (G1) was subjected to physical exercises and consumption of Cymbopogon citratus; group 2 (G2) had consumed only Cy...

Malgré la hausse de la température atmosphérique pendant la grande saison de pluies, la Fédération Congolaise de Football (FECOFOOT) organise les matchs à 14 heures. Dans le but d’évaluer les paramètres physiologiques des footballeurs par poste de jeu et la distance totale qu’ils parcourent au cours d’un match éprouvant de football en république du...

Background: Mangiferaindica L. and Persea Americana L. are two fruit trees very well-known and appreciated by the people of Benin for their fruits. The seeds from the fruits of these plants, despite their growing interest in pharmacology, are considered as environmental waste not yet recovered. This work aims to determine the phytochemical composit...

Plants are large reservoir of active ingredients used to treat many pathologies including brain pathology. This research work aims first at reviewing the existing literature pertaining to those plants used in traditional African medicine to treat neurological and / or psychiatric diseases. In addition, it performs a phytochemical screening of twent...

Notre affiche présente une étude statistique et analyse phytochimique d'une partie des plantes utilises dans la médecine traditionnelle pour traiter les maladies neurologiques

l'affiche présente les résultats d’une investigation de des feuilles de palmier a huile utilisées traditionnellement dans le traitement du paludisme au Bénin

Dans la pharmacopée béninoise, nombreuses sont les plantes aromatiques utilisées dans le traitement traditionnel de l’ulcère de Buruli , maladie provoquée par Mycobacterium ulcerans, une mycobactérie lipophile aimant vivre dans les adipocytes. Les huiles essentielles, étant des produits naturels volatils et liposolubles directement extraits de ces...

RESUME L'épilepsie est une maladie neurologique chronique caractérisée par la répétition des crises épileptiques et dont la prévalence est élevée dans les pays en voie de développement. L'accès aux soins appropriés pour sa prise en charge étant difficile dans nos pays, un grand nombre de patients a recours à l'usage de plantes médicinales dont Opil...

Hepatic disease is a public health problem because of the devastation it causes to people. The purpose of this work is to evaluate the antioxidant activity of a plant, such as Lophira lanceolata, commonly used in the treatment of liver diseases in Benin. Phytochemical screening of aqueous and ethanolic extracts according to traditional use revealed...

Croton lobatus L. is medicinal plant widely used in traditional medicine, but little known in literature for its biological properties. Aims were to study its phytochemical composition and some biological properties and influence of acid hydrolysis on biological activities and chemical composition of Croton lobatus L. extracts. Successive extractio...

Article Info Leaves of Landolphia calabarica are used traditionally in Benin to treat wounds. This survey aims to value the healing properties of Landolphia calabarica at Wistars rats. Analysis phytochimique, the content in total phenols and the cytotoxicity has been done on the aqueous extract of Landolphia calabarica leaves. The healing activity...

As part of the development of traditional medicine rich in Africa and particularly in Bénin, several studies have been conducted for years to evaluate the ethnopharmacological properties of medicinal plants. It is in this context that Mitragyna inermis is known for many of these properties mentioned in the traditional pharmacopoeia and whose biolog...

Les plantes aromatiques jouent un rôle considérable dans plusieurs secteurs notamment dans la médicine traditionnelle. Dans le but de la valorisation de ces plantes, ce travail a pour objectif d’évaluer la relation composition chimique-activité antioxydante, et la toxicité des huiles essentielles de Cymbopogon citratus et Cymbopogon schoenantus acc...

Afzelia africana (Smith) is medicinal plant of traditional pharmacopoeia, belong to Leguminosae-Caesalpinoideae family, used for neurological diseases. This study aimed to evaluate the anticonvulsant activity of Afzelia africana leaves' aqueous extract on an animal model. Beforehand phytochemical screening and acute oral toxicity have been carried...

The objective of this study is to study the phytochemistry of the anti-bacterial activity of thirteen plants used in traditional medicine to treat typhoid fever in Benin. For this fact, we carried out the phytochemical screening, then the antibacterial activity was carried out by the micro-dilution method. The dosage of polyphenols was made on the...

Melaleuca quinquenervia is a plant well-known for its medicinal properties. Its leaves are mainly used for the treatment of respiratory diseases. The present study aims was to appreciate the anti-inflammatory properties of the essential oil from the leaves of Melaleuca quinquenervia (Cav.) ST Blake Myrtaceae (Niaouli). Phytochemical analysis of the...

Fungi of the genus Amanita (Basidiomycota) contain secondary metabolites very useful for human welfare. They are much exploited by tropical African people for various purposes. The objective of this study is to identify the myco-chemical groups and evaluate the antioxidant activity of eleven macromycetes of the genus Amanita harvested in woodlands...

The present study, carried out on Cymbopogon citratus was interested in volatile and no-volatile extracts of the plant. It focused on the effect of two types of extracts on eleven strains of bacteria. Chemical analysis of the volatile extract obtained with a yield of 2.28% revealed the presence of 72.91% of citral and other minority compounds. The...

The most cited plant drugs during an ethnobotanical survey conducted for traditional healers and resource persons in southern Benin, used in the treatment of female infertility, were the subject of a phytochemical screening. It aims to determine the chemical substances that are conferred on the plants. These chemical substances are the pharmacologi...

Procreation has been and continues to be today the fundamental reason for marriage in Africa since immemorial time. Infertility of the couple is seen as a fatality that it seeks to fight at all costs for a good part of his life. To know the recipes used in Benin to treat female infertility, a survey was undertaken towards the traditional healers an...

RESUME Objectif : L'usage de Ocimum gratissimum Lamiaceae (Basilic tropical) est très répandu au Bénin. Cette utilisation repose sur les connaissances empiriques des populations. Il est légitime de se demander si les vertus attribuées à cette plante reposent sur des bases scientifiques et sa consommation sans conséquences néfastes pour la santé hum...

The aim of this study was to investigate the antibacterial effect of the crude starter " kpètè-kpètè " and lactic acid bacteria used during the production of " tchoukoutou. " To achieve this, a total of 11 lactic acid bacteria and 40 starter samples were collected from four communes. The samples were tested on 29 gram + and − strains by disk diffus...

Parkia biglobosa is a plant used in traditional medicine for the treatment of certain diseases. In order to scientifically appraise some of the anecdotal, folkloric ethno medical uses of P. biglobosa, this study aimed at making phytochemical screening and evaluating some biological activities of P. biglobosa leave and bark extracts. These organs po...

Bridelia ferruginea, Lophira lanceolata and Oxytenanthera abyssinica are medicinal plants whose mixture is used for the treatment of diabetes by traditional medicine in Benin. The aim of this work is to evaluate the anti-hyperglycemic activity of each of these plants to their synergy of mixture extract on type 2 diabetes. The experiments performed...

Also called ahlonmè in Ewe, Conyza aegyptiaca (L.) Aiton (C. aegyptiaca) is one of the plants used for diabetes treatment in West Africa. In type 2 diabetes patients, enhanced glucose output by liver contributes to hyperglycemia and inhibition of hepatic glucose production favors glycemic control. In this study, we analyzed the effect of C. aegypti...

Objective: The study aims to investigate some physical and technological parameters of varieties of maize collected from the most representative areas of maize production in the southern part of Benin, and mainly used by the populations of those areas. Method: The chemical composition, physical and technological characteristics of the grains were d...

Faced with the increasing growth of microorganism's resistance to conventional antibiotics, the search of new bioactive molecules having pharmaceutical interest is more than ever committed. This study aimed to evaluate in vitro the effectiveness of seven mouthwashes formulated from essential oils of Ocimum gratissimum, Ocimum basilicum, Cymbopogon...

Objectif : La présente étude, sur Momordica charantia Linn (Cucurbitaceae), communément appelé margose une plante très utilisée pour le traitement de nombreuses maladies, est menée dans la ville de Cotonou au Bénin. Elle vise à vérifier la portée scientifique des usages empiriques que fait la population de cette plante, afin de promouvoir son utili...

This study aimed firstly to determine the chemical composition, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of essential oils extracted from Ocimum gratissimum, Ocimum basilicum, Laurus nobilis and Melaleuca quinquenervia collected from Benin (West Africa) on five oral microorganisms (Micrococcus luteus ATCC...

Medicinal plants have an important place in the therapy mechanism of Benin's population. According to the World Health Organization, 75% of African populations use plants for treatment. Many researchers used to work with tweens. Thus, this work aimed to study the influence of the use of different types of tween in the evaluation of the antimicrobia...

Combretum micranthum, is an exotic medicinal plant used generally in African pharmacopoeia and particularly in Benin against several bacterial infections. In this study, the antimicrobial activity of ethanol and ethyl acetate extracts of leaves of this plant, were tested in vitro on 70 strains of Staphylococcus aureus isolated from three skin infec...