Gayani Liyanage

• MBBS
• Lecturer at Faculty of Medicine, University of Ruhuna

Objective The "Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls" (SARC-F) is a simple, five-item tool used to identify individuals with suggestive signs of sarcopenia. This study assessed the validity of the Sinhala version of the SARC-F, evaluating its ability to detect sarcopenia in older women and its potential to pr...

Psoriasis is associated with psychological distress among the affected due to unsightly skin lesions, chronicity and the cultural and social stigma linked with the disease. The pathophysiological link between psoriasis and depression creates a vicious cycle in the skin and brain axis. This study evaluates the psychological comorbidity of patients w...

Objective Adverse Drug Reactions (ADR) add a significant clinical and economic burden to the healthcare system of a country. We present an overview of the different approaches of ADR reporting systems worldwide and their evolution over time. Methods A systematic review of the literature was made based on PubMed and the Cochrane database of systema...

Objective: Skin lightening agents are popular in southern Asia, but there is dearth of evidence on their effectiveness on Fitzpatrick IV/V skin types. This study was designed to assess the depigmenting efficacy of commercially available and specifically formulated ointments using the Mexameter® (MX 18). Methods: This single center prospective st...

Introduction/objectives Psoriasis is a chronic inflammatory dermatosis with significant physical and psychological impact leading to negative influence on the quality of life among patients with psoriasis. Other than the disease characteristics many external factors could operate in South Asian context. Lack of a reliable disease-specific instrumen...

Introduction/objectives: Psoriatic arthritis (PsA) occurs in one-third of patients with psoriasis and mostly remains undetected leading to debilitating deforming arthritis, eventually. The Psoriasis Epidemiology Screening Tool (PEST) is a quick and valid tool, widely used to detect PsA in clinical practice, and it has been validated to many langua...

PurposeDiabetes compromises bone strength resulting increased risk of osteoporosis. Objective of this study was to determine the effect of vitamin D given to patients with early diabetic renal disease on BMD and BMC.Methods Patients with diabetic nephropathy were recruited. Treatment group received 50,000 IU of vitamin D3 intramuscularly and the co...

Introduction: Diabetes mellitus (DM) impairs bone strength resulting in an increased risk of fractures. This study was designed to determine the association between bone mineral density (BMD) and vertebral fractures among a selected group of patients with Type 2 diabetes mellitus. Methods: This cross-sectional study included patients with diabetes,...

Background: Peripheral arterial disease (PAD) is an important marker of cardiovascular (CV) risk and the risk of PAD is markedly increased in patients with type 2 diabetes mellitus (T2DM). Consequently, early diagnosis and treatment of PAD in patients with T2DM are critically important to reduce the risk of CV events. The aim of this study was to...

Introduction. Onset of nephropathy in patients with type 2 diabetes (T2DM) increases the cardiovascular disease (CVD) risk. Association of the parameters of diabetic nephropathy such as albuminuria and estimated glomerular filtration rate (eGFR) with predicted CVD risk has not been studied in Sri Lankan patients with T2DM. Methods. In a cross-secti...

Background:Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes for chronic liver disease in Asians. It occurs more commonly in patients with type 2 diabetes mellitus (T2DM).However, data on prevalence and associations of NAFLD among Sri Lankans with diabetes are lacking. The main aim of this study is to investigate the preval...

Inhalers and inhaler devices

Techniques of insulin administration - Video

Background: Microalbuminuria signifies the onset of diabetic nephropathy, but normoalbuminuric patients with diabetes who have a low Glomerular Filtration Rate (GFR) are not uncommon. The purpose of the study was to estimate the prevalence of such patients and to assess the clinical correlates. Methods: Cross-sectional study included patients wi...

Introduction Implementation of effective measures to control rising burden of cardiovascular diseases among patients with type 2 diabetes mellitus (T2DM) requires information on the adequacy of control and identification of specific groups with suboptimal control of blood glucose, lipids and blood pressure. Methods A cross-sectional study of patie...

Introduction Influence of dietary and drug compliance of patients with diabetes on attainment of optimal metabolic (glucose and lipid) control remains underexplored in developing countries. Materials and methods Self-reported dietary and drug compliance score of 0–10, glycosylated hemoglobin (HbA1c), and low-density lipoprotein (LDL) levels were o...

Background: Recognition of cardiovascular (CVD) risk profile and its patterns at the time of diagnosis of diabetes would enable adoption of most appropriate primary prevention strategies to reduce morbidity and mortality from vascular disease. We aimed to study the prevalence and pattern of modifiable CVD risk factors in patients at the time of dia...

Background: Despite different management strategies, progression of proteinuria occurs in a sizable category of patients with diabetic nephropathy (DN). Increase in serum renin levels induced by the renin–angiotensin system (RAS) may contribute to this. Vitamin D therapy is found to have an inhibitory effect on the RAS. We aimed to study the effect...

Aims: Aim of this study was to determine the effect of high dose vitamin D given to patients with early diabetic renal disease on systolic and diastolic blood pressure, total cholesterol (TC), low-density lipoproteins (LDL), triglycerides (TG) and high density lipoproteins (HDL) in a randomized controlled trial MATERIALS AND METHOD: Patients with...

Multiple Choice Questions (MCQs) is a form of an objective assessment which is most frequently used, evaluation component in examinations of medical undergraduates. There are two types of MCQs. They are Single Best Response Questions (SBRs) and True or False type questions. In True or False type questions, responders need to mark whether the given...

Aims: We aimed to study the prevalence and associations of suboptimal high density lipoproteins level, a characteristic feature in diabetic dyslipidemia among patients under statin therapy. Materials and methods: From a database of 2416 patients, data on age, gender, duration of diabetes, body mass index (BMI) and waist circumference (WC), low d...

Introduction First degree relatives of patients with type 2 diabetes have a high risk of pre-diabetes and diabetes. We aimed to study the predictors of abnormal glucose tolerance in this category. Methods Previously healthy 157 first degree relatives of type 2 diabetes were studied. Age was noted and body mass index (BMI) was calculated. All underw...

What anthropometric parameters and lipid parameters predict abnormal glucose tolerance in the first-degree relatives of patients with type Abstract Introduction First degree relatives of patients with type 2 diabetes have a high risk of pre-diabetes and diabetes. We aimed to study the predictors of abnormal glucose tolerance in this category. Metho...