Gaurav KumarLovely Professional University | LPU · Discipline of Microbiology
Gaurav Kumar
M.Sc., Ph.D
About
139
Publications
316,103
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Introduction
I am currently working in the Department of Microbiology, Lovely Professional University. My research fields include Ethnobotany, Microbiology, and Biotechnology.
Additional affiliations
April 2024 - present
October 2021 - March 2024
Lovely Professional University
Position
- Professor (Associate)
July 2015 - September 2021
Education
August 2008 - July 2013
July 2006 - June 2008
June 2002 - May 2006
Publications
Publications (139)
To analyze the phytochemical composition and in vitro antioxidant properties of aqueous extract of Aerva lanata (A. lanata) stem.
During the preliminary phytochemical analysis, the aqueous extract of A. lanata was screened for the presence of carbohydrates, proteins, phenolic compounds, oil and fats, saponins, flavonoids, alkaloids, tannins and phy...
The knowledge of traditional medicine and medicinal plants and their study of scientific chemical principles may lead to the discovery of newer and cheaper drugs. Lantana camara is well known to cure several diseases and used in various folk medicinal preparations. In last few decades, scientist and researchers around the globe have elaborately stu...
Panchatikta is an Ayurvedic multiherbal combination containing five bitter-tasting drugs—Azadirachta indica, Tinospora cordifolia, Justicia adhatoda, Solanum virginianum, and Trichosanthes dioica. The objective of this study is to develop standards for Panchatikta ingredients using pharmacognostic parameters and to analyze the chemical composition....
Nanobiotechnology, at the intersection of nanotechnology and biology, represents a burgeoning field poised to revolutionize medicine through the use of advanced nanocarriers. These nanocarriers, endowed with distinctive physiobiological attributes, are instrumental in diverse therapeutic domains including drug delivery for microbial infections, can...
The extracellular synthesis of titanium dioxide nanoparticles has been investigated using the marine actinobacteria, Streptomyces sp. LK-3. UV–visible spectroscopy, XRD, AFM and SPM techniques were used to characterize the particle size, morphology and found to be within the range of 3.5–92 nm with spherical and oval shape. Titanium dioxide nanopar...
Nanobiotechnology has ushered in a new era of scientific discovery where the unique properties of nanomaterials, such as gold nanoparticles, have been harnessed for a wide array of applications. This review explores gold nanoparticles' synthesis, properties, and multidisciplinary applications, focusing on their role as biosensors. Gold nanoparticle...
For the last two decades, the escalating demands and subsequent depletion of fossil fuels have led to the search for suitable alternatives. A potential solution to the limitation of fossil fuels is “Biofuel.” Biofuels are referred to as fuels that are derived from biological substances like crops, microorganisms, wood, waste matter, etc. First-gene...
Environmental impacts, energy applications, photocatalysis on semiconductor-based hybrid materials has drawn a lot of interest recently. Having a gap in between 1 and 2 eV, the Transition Metal Dichalcogenide (TMDSc) group of materials can be good option for a two-dimensional material. A straightforward microwave synthesis technique was used for sy...
Since the COVID-19 outbreak, the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) virus has evolved into variants with varied infectivity. Vaccines developed against COVID-19 infection have boosted immunity, but there is still uncertainty on how long the immunity from natural infection or vaccination will last. The present study attempt...
Nanotechnology is an emerging area of science that deals with making and designing of nanosized objects having widespread applications. Nanomaterials or nanosized objects have that have at least one dimension in the nanoscale range. Nanozymes are enzymes or nanomaterials showing enzyme-like properties. Nanozymes have similar advantages that are ass...
Foodborne infections pose a substantial global threat, causing an estimated 600 million illnesses and resulting in approximately 420,000 deaths annually. Among the diverse array of pathogens implicated in these infections, Escherichia coli (E. coli), specifically the O157 strain (E. coli O157), emerges as a prominent pathogen associated with severe...
This review paper presents a comprehensive bibliometric analysis of the global scientific research pertaining to carbapenem-resistant Acinetobacter baumannii (CRAB) from the years 1996 to 2023. The review employs a systematic approach to evaluate the trends, patterns, and collaborative networks within the CRAB research landscape, shedding light on...
Rapid growth in industrialization sectors, the wastewater treatment plants become exhausted and potentially not able to give desirable discharge standards. Many industries discharge the untreated effluent into the water bodies which affects the aquatic diversity and human health. The effective disposal of industrial effluents thus has been an imper...
The rising environmental issues have intensified research in developing microbial fuel cells (MFCs) as a green and sustainable source of energy generation. The discovery of electroactive bacteria (EABs) in the 1980s and their application in MFCs greatly improved energy generation as they aid in transferring electrons to the anodic surface. EABs can...
Omega-3 fatty acids or polyunsaturated fatty acids known as are indispensable to human health and are more commonly referred to as “healthy fats.” These include improving neuronal functioning and promoting cardiac health by decreasing triglycerides, as well as controlling blood pressure, reducing hypertension, improving mental health, and checking...
Microorganism plays a crucial role in manufacturing food products we consume daily, including traditional oriental foods, single-cell proteins, alcoholic beverages, dairy products, and many more. This chapter is an overall discussion about the role of microorganisms in food production from pre-historic times to till today. This chapter deals with f...
“Pakhoi” is an ethnic drink of the Tons valley, Uttarakhand, India produced by fermenting jaggery and barley with the help of a starter culture called “keem”. In the present study, we investigated the microbial diversity and associated functional potential of “keem” using shotgun metagenome sequencing and amplicon sequencing. We also compared the t...
The production and disposal of plastics have become significant concerns for the sustainability of the planet. During the past 75 years, around 80% of plastic waste has either ended up in landfills or been released into the environment. Plastic debris released into the environment breaks down into smaller particles through fragmentation, weathering...
The current study reports the synthesis of sustainable nano-hydroxyapatite (nHAp) using a wet chemical precipitation approach. The materials used in the green synthesis of nHAp were obtained from environmental biowastes such as HAp from eggshells and pectin from banana peels. The physicochemical characterization of obtained nHAp was carried out usi...
Environmental stress affects food productivity by producing reactive oxygen species (ROS) that damage cell organelles and biomolecules, leading to apoptosis. Plants have developed a variety of defense responses over time to counteract the detrimental effects of biotic and abiotic stresses. However, in order to combat climate change and the deterior...
Cosmetics and personal care items are used worldwide and administered straight to the skin. The hazardous nature of the chemical surfactant utilized in the production of cosmetics has caused alarm on a global scale. Therefore, bacterial biosurfactants (BS) are becoming increasingly popular in industrial product production as a biocompatible, low-to...
The clinical applications of nanotechnology are emerging as widely popular, particularly as a potential treatment approach for infectious diseases. Diseases associated with multiple drug-resistant organisms (MDROs) are a global concern of morbidity and mortality. The prevalence of infections caused by antibiotic-resistant bacterial strains has incr...
Today, fossil fuel is the primary source of energy worldwide. Because of rising global population and demands, the decline of fossil energy is a problem for future supply. Aside from accessibility, pollutants created by fuel combustion are a global health and environmental issue, contributing to global climate changes, destruction of the environmen...
This research effort aims to evaluate the hazardous potential of the redox state (OH-) of zero-valent iron nanoparticles (nZVI) and its histopathological and oxidative stress toward Mozambique tilapia, Oreochromis mossambicus. X-ray powder diffraction (XRD) validated the nZVI nanoparticles' chemical composition, while transmission electron microsco...
Biofilm development by bacteria is a serious issue in many different sectors, including the food, pharmaceutical, water, petroleum, and others. Because biofilms are difficult to remove due to their capacity to survive in bad environments, attempts were undertaken throughout this work to biologically manufacture gold nanoparticles with possible anti...
The biogenic method for synthesis of nanoparticles is preferred over the traditional strategies, on account of its ease, environmental friendliness, and cost-effectivity, wherein fungi endorse themselves to be the most appropriate precursor for the same. In recent times numerous metal nanoparticles have been reported to exhibit significant therapeu...
Drug resistance is one of the problems affecting the world where drug-resistant Escherichia coli and Klebsiella pneumoniae have been shown to be ubiquitous, frequently isolated from foods and commonly associated with surgical site infection in hospitals worldwide. The aims of this work were to analyze the antibacterial activity of root extracts of...
In the current scenario nanoparticles (NPs) have gained a breathtaking impetus due to their multidimensional applications in varied fields. In the present effort, biogenic synthesis of Zinc Oxide nanoparticles (ZnO NPs) was carried out using aqueous extract of dried powder of Emblica officinalis (Amla). Physicochemical characterization of nanoparti...
Biosynthesis of silver nanoparticles (AgNPs) using plant extracts has become a promising alternative
to the conventional chemical synthesis approach. In this study, cost-effective synthesis of
AgNPs was attempted using leaves extract of Litchi chinensis. Bio-reduction reaction for the synthesis
of NPs was checked by confirming the presence of AgNPs...
Metal complexes with heterocyclic Schiff bases are of substantial curiosity for the chemists. Ligand modifications are easily accessible due to preparative simplicity, structural variability and tunable electronic properties. Hetero atoms like N and O when incorporated in Schiff bases play a key role at binding sites in metallobiomolecules Transiti...
During the present study, methanolic extract of M. nigra and A. heterophyllus leaves were analyzed for antioxidant and anti-inflammatory activity by in vitro methods. The preliminary phytochemical studies showed the presence of phenolic compounds, flavonoids and tannins in both plants while alkaloids and saponins were missing. Determination of anti...
Cinnamomum verum is a spice plant used widely known for its medicinal and pharmaceutical properties. The goal of the presented study was to evaluate phytochemical composition and antimicrobial activity of aqueous extract of C. verum. During study the antimicrobial activity of the extract was evaluated against 5 UTI causing bacteria while the extrac...
Terminalia bellirica is one of the very popularly used plant in traditional medicine for the treatment of various diseases. Fruits of T. bellirica is having several applications as medicine and used in various household activities, however leaves remains relative less explored part. Therefore during this study solvent extract of T. bellirica was st...
Embelia ribes is an important medicinal plant belonging to family Primulaceae. This plant is commonly known as false black pepper plant and since ancient time being used as in several herbal medicines for the treatment of various diseases. Almost all parts of E. ribes such as stem, leaves, roots, seeds and barks possess very good medicinal properti...
Bacteria from all taxa synthesize various valuable, structural, and functional polysaccharides. Bacterial polysaccharides are biodegradable, biocompatible, and naturally nontoxic biopolymers. The bacteria secrete polysaccharides into the environment. These polysaccharides are referred to as exopolysaccharides (EPS). These microbial polysaccharides...
This book presents a comprehensive overview of the use of microorganisms and microbial metabolites as a future sustainable basis of agricultural, environmental and industrial developments. It provides a holistic approach to the latest advances in the utilization of various microorganism bioprospecting including their wide range of applications, tra...
Objectives: Microbial spoilage of food is one of the leading causes of food scarcity worldwide, which could have devastating effect on the socioeconomic of any country. Along with classical food preservation methods, various innovative approaches can significantly increase the food safety. Biosurfactants are the amphiphilic microbial metabolites, w...
Objective: This study was designed to study the prevalence and antibiotic susceptibility patterns of Acinetobacter sp. as isolated from patients lodged in intensive care units (ICUs) of a tertiary care hospital, Ludhiana, Punjab, India.Methods: The clinical samples were simultaneously streaked on Blood agar and MacConkey agar. The identification of...
Biosurfactants are surface active biomolecules produced by a variety of microorganisms and their amphiphilic nature can reduce the tension between aqueous solutions and the hydrocarbon mixtures (such as oil). In addition, biosurfactants can emulsify and degraded a variety of hydrocarbons present in oil and thus enables their applications in the cle...
Urinary tract infections (UTIs) are among ten most prominent complications encountered by diabetic patients. UTIs also responsible for worsening the clinical condition of diabetic patients by causing damage tothe urinary tract. During the study, a total of 67 urine samples were collected from (different age groups and both gender) the diabetic pati...
Plant pathogenic fungi are one of the most diverse and important groups of microorganisms known to attack a variety of plants. These fungi result in great economic losses and also affects large landscapes and its habitats worldwide. Recent research and developments in the science have significantly help in understanding the disease mechanisms and d...
Phytochemical evaluation and antioxidant potential in vitro.
Present study was aimed to analyze berberine concentration in Tinospora cordifolia stems collected from Ficus,
Azadirachta, Syzygium, Populus and Eucalyptus. High Performance Liquid Chromatography equipped with UV
detector was used for analytical study of berberine from the stem of Tinospora cordifolia. Methanol (100%) as a
diluent was used for...
Staphylococcus aureus is a very common food born pathogenic bacteria found in raw and under cooked chicken meat samples and its consumption may lead to the infection and/or toxicity in consumers. Therefore, this study was designed to study the prevalence and antibiotic sensitivity pattern of S. aureus in chicken meat samples collected from, retail...
Urinary tract infection (UTI) is a very common and prevalent type of bacterial infection in females, therefore current study was designed to investigate the prevalence of microorganisms in female UTIs cases and their resistance patterns. During the study, a total of 281 urine samples were collected from females clinically suspected for urinary trac...
The objective of this study was to assess the mosquito controlling potential of aqueous extract of Nerium oleander leaves against the primary and secondary vectors of Japanese encephalitis (Culex tritaeniorhynchus and Cx. gelidus). Phytochemical screening of N. oleander leaves exhibited the presence of saponins, proteins, flavonoids, alkaloids, tan...
This study describes a novel biological route for the biosynthesis of silver oxide nanoparticles utilising the aqueous extract of Callistemon lanceolatus D.C. leaves. Formation of silver oxide nanoparticles was confirmed by UV–visible spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscope–energy dispersive X-ray spectro...
The current study was aimed to evaluate phytochemical composition and antioxidant property of red, white and yellow flower yielding varieties of Bougainvillea glabra leaves by various in vitro methods. Antioxidant activity of all the three varieties was analyzed by DPPH radical scavenging assay. Red variety showed highest DPPH radical scavenging ac...
The aim of this study is to analyze the phytochemical composition and antioxidant activity of Ficus elastica (F. elastica). Antioxidant activity of methanolic extract of Ficus elastica leaves was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, total antioxidant activity test, iron chelating activity test and reducing pow...
Marine Bacillus species are potent producers of novel enzymes. Marine Bacillus VITRKHB was observed to be efficient for cellulolytic activity. It was employed for the production of extracellular cellulase. Cellulase was partially purified to 1.6-fold in a stepwise manner by ammonium sulfate precipitation, dialysis, and DEAE ion exchange chromatogra...
The present study was focused on screening and characterization of tyrosinase enzyme produced by marine actinobacteria and its application in phenolic compounds removal from aqueous solution. A total of 20 strains were isolated from marine sediment sample and screened for tyrosinase production by using skimmed milk agar medium. Among 20 isolates, t...
The aim of this study was to investigate the antioxidant and DNA damage inhibition potential of methanolic extract of Carissa carandas leaves. Extract was found to exhibit significant (p < 0.05) dose dependent DPPH radical scavenging activity (IC50 value= 73.12 μg/ml), total antioxidant activity, H2O2 scavenging activity (IC50 value 84.03 μg/ml), r...
Present study is focused on the synthesis of titanium dioxide nanoparticles (TiO2 NPs) from marine actinobacteria and to check their antibiofouling activity against the isolated biofouling bacteria. A total of five actinobacterial strains were isolated from Chennai marine sediments, Tamilnadu, India, which were designated as SV1-SV5. Two biofouling...
The aim of this study was to evaluate the phytochemical composition and antioxidant potential of the Ficus benghalensis (F. benghalensis) by in vitro methods. Methanolic extract of F. benghalensis leaves was evaluated for the presence of carbohydrates, proteins, phenolic compounds, oil and fats, saponins, flavonoids, alkaloids and tannins by using...
Ipomoea fistulosa is an evergreen shrub with heart shaped leaves which is used for the treatment of various diseases in traditional medication. In this study, aqueous extract of I. fistulosa leaves was evaluated for phytochemical composition, antioxidant activity and cytotoxic activity by various in vitro methods. Phytochemical screening of the I....
The present study was focused on isolation, screening, characterization and application of biosurfac-tant producing marine actinobacteria. Twenty actinobac-teria were isolated from marine water sample and were primarily screened for biosurfactant production using hemolytic activity method. Among the 20 isolates, six showed positive result for hemol...
The study was planned to screen the marine actinobacterial extract for the protease inhibitor activity and its anti- Pf activity under in vitro and in vivo conditions. Out of 100 isolates, only 3 isolates exhibited moderate to high protease inhibitor activities on trypsin, chymotrypsin and proteinase K. Based on protease inhibitor activity 3 isolat...
The aim of the present study was to increase the production of antibacterial compound from marine actinobacteria by the effect of chemical mutation as well as optimization of media using Response Surface Methodology (RSM). The efficiency of the antibacterial compound was tested against clinical isolate of Pseudomonas aeruginosa. Mutational effect w...
Elaeocarpus ganitrus Roxb. (E. ganitrus) is an evergreen tree belongs to the family Elaeocarpaceae. E. ganitrus is an important medicinal plant in traditional medication system and mainly used to cure nervous system related disorders. In recent past, E. ganitrus has been extensively studied for its medicinal properties by advance scientific techniq...
The study focused on the combination of marine actinobacterial extract and its mediated zirconium oxide nanoparticles for anti-biofouling application against the isolated biofouling bacteria. Streptomyces sp.VITSDSB was used for the synthesis of zirconium oxide nanoparticles, since it showed the maximum potential for the synthesis of nanoparticles....
The aim of the present study was to isolate microorganism that produces biosurfactant and to optimize its production. Lipase and hemolytic activity were performed as primary screening procedures. Three potential isolates (GMPI to GMP3) were subjected to secondary screening by Drop collapsing method, Oil displacement method and Emulsification index....