Galit Almoznino

• Associate Professor at Hebrew University of Jerusalem

Background The use of Cone-Beam-Computed-Tomography (CBCT) is rapidly increasing in dentistry. This study aimed to evaluate CBCT use among dentists across various fields and how it is affected by various measures. Methods We sent an anonymous questionnaire to Israeli dentists, which assessed the clinical use (including requested output: cross-sect...

Background Denture‐induced oral Lesions (DIOLs) often manifests shortly after the placement or adjustment of new or realigned dentures, frequently resulting in severe pain and discomfort. Objectives This study aimed to classify DIOLs placing a particular emphasis on assessing the associated pain. Methods A prospective case study was conducted inv...

Objectives: Sedation is commonly utilized for individuals otherwise unable to receive dental treatment; such as those with disabilities, medically complex conditions, and dentophobics. We aimed to characterize the profiles of patients receiving various types of sedation and assess the corresponding success rates. Materials and methods: A 5 years...

The objective of this study was to analyze the associations between temporomandibular disorders (TMDs) and metabolic syndrome (MetS) components, consequences, and related conditions. This research analyzed data from the Dental, Oral, Medical Epidemiological (DOME) records-based study which integrated comprehensive socio-demographic, medical, and de...

This study primarily aimed at developing a novel multi-dimensional methodology to discover and validate the optimal number of clusters. The secondary objective was to deploy it for the task of clustering fibromyalgia patients. We present a comprehensive methodology that includes the use of several different clustering algorithms, quality assessment...

Simple Summary This study analyzed the associations of taste dysfunctions as measured by validated taste strips with demographics and co-morbidities. The study demonstrated that taste dysfunction was associated with older age, male sex, and co-morbidities such a previous major trauma, being under chemotherapy, zinc deficiency, burning mouth syndrom...

Background The association between orthodontic treatment and temporomandibular disorders (TMD) has been contentious in the literature. Objectives To analyse the associations between orthodontic treatment and TMD diagnosis and diseases characteristics. Methods This case–control study included 291 individuals, 192 TMDs and 99 controls. All patients...

This study aimed to analyze the associations between periodontitis and metabolic syndrome (MetS) components and related conditions while controlling for sociodemographics, health behaviors, and caries levels among young and middle-aged adults. We analyzed data from the Dental, Oral, and Medical Epidemiological (DOME) record-based cross-sectional st...

Periodontal disease is a complex and progressive chronic inflammatory condition that leads to the loss of alveolar bone and teeth. It has been associated with various systemic diseases, including diabetes mellitus and obesity, among others. Some of these conditions are part of the metabolic syndrome cluster, a group of interconnected systemic disea...

This paper is aimed at comprehensively reviewing olfactory and gustatory disorders (OGD) caused by SARS-CoV-2 in children and adults. An electronic and manual search was done on three databases: MEDLINE, Embase, and Web of Science (WoS). Inclusion criteria included publications written in English, involving humans in the age range of 0-99 years tha...

This study aimed to analyze the associations of obstructive sleep apnea (OSA) with dental parameters while controlling for socio-demographics, health-related habits, and each of the diseases comprising metabolic syndrome (MetS), its consequences, and related conditions. We analyzed data from the dental, oral, and medical epidemiological (DOME) cros...

Objective: To assess the combination of salivary gland intra-ductal irrigations (IG) followed by sialoendoscopy irrigations (SI) of the parotid gland on the improvement of salivary gland secretory dysfunction (SGSD). Methods: We retrospectively analyzed the records of SGSD patients who underwent major salivary gland IG followed by SI during 2014...

The objectives of the research were to analyze the association between Body Mass Index (BMI) and dental caries using novel approaches of both statistical and machine learning (ML) models while adjusting for cardiovascular risk factors and metabolic syndrome (MetS) components, consequences, and related conditions. This research is a data-driven anal...

This study aimed to analyze the associations of nonalcoholic fatty liver disease (NAFLD) with dental parameters, while controlling for socio-demographics, health-related habits, and each of the metabolic syndrome (MetS) components, consequences, and related conditions among a nationally representative sample of young and middle-aged adults. To that...

Objective: Occlusal stabilization splints (OSSs) are first-line therapy for temporomandibular disorder (TMD) and sleep-related-bruxism (SRB). The main goal of this study was to quantify adherence rates to OSS therapy in TMD patients and among non-painful conditions such as clenching and bruxism. It was hypothesized that adherence rates would be si...

The study aimed to analyze the uses of cone-beam computed tomography (CBCT) in the diagnosis and treatment in various dental specialties. This 4-year cross-sectional study analyzed the records of 1409 individuals who underwent a CBCT at the Oral and Maxillofacial Center at Sheba Medical Center, Israel. The average age of the patients was 27.9 ± 11....

Background "SOS teeth" are teeth that need to be treated first, and represent dental teeth with deep caries seen clinically and radiographically which may require root canal treatment or extraction. The aims of the present research were to study the associations of SOS teeth with: socio-demographic parameters, dental attendance patterns, health-rel...

Objective To investigate the immunoexpression of stem cell markers (Nanog, SOX2, Oct4, CD34) in odontogenic cysts and tumors. CD34 was investigated as a marker for stromal fibroblast/fibrocyte cells (CD34+SFCs). CD34+SFCs were also investigated ultrastructurally. The physical aggregation of collagen fibers was examined by picrosirius red stain and...

Simple Summary There are conflicting results existing regarding the association between dental status and metabolic syndrome (MetS). This study aimed to analyze the association between the sum of the standard dental unit (SDU) scores of planned (SDU-P) and delivered (SDU-D) dental procedures per patient with MetS. Included were data from the Dental...

The outbreak of the COVID-19 pandemic caused changes in all aspects of daily life, including adjustments in dental work. The COVID-19 vaccine was rapidly approved, provoking hesitations among the general public as well as dental staff. The aim of this study is to assess the views and beliefs of IDF dental staff regarding COVID-19 and its vaccine Me...

Both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are classified as autoimmune diseases, where the body's own immune response causes it to attack the host tissues, as if the latter were antigens. RA is the most common autoimmune disease that affects joints. The clinical diagnosis of RA is based on the history and examination, in...

Objectives: To investigate the association of psychiatric disorders with (1) caries experience, (2) periodontal status, and (3) metabolic syndrome (MetS) components. Method and materials: This 7-year cross-sectional study retrospectively analyzed the medical records of 504 individuals aged 18 to 90 years who attended the student dental clinic. C...

Simple Summary Relatively few studies analyzed the association between cognitive performance and dental status. This study aimed to analyze the association between cognitive performance and dental caries. Included were data from the Dental, Oral, Medical Epidemiological (DOME) study records-based research, which integrated large socio-demographic,...

The study aimed to measure the pre-operative oral health-related quality of life (OHRQoL) and to identify patient and teeth pathologies associated with worse OHRQoL among patients attending mandibular third molar tooth extraction. Data were collected preoperatively from 199 patients attending surgical removal of their mandibular third molar. To tha...

Conflicting results have been published regarding the associations between dental status and hypertension. This study aims to explore whether or not hypertension is associated with dental status among young to middle-aged adults. To that end, data from the Dental, Oral, Medical Epidemiological (DOME) study were analyzed. The DOME is a cross-section...

Abstract Objectives: To develop and present the methods utilized for the Dental, Oral, Medical Epidemiological (DOME) study. Methods: The DOME is an electronic record-based cross-sectional study, that was conducted to measure the dental, periodontal, and oral morbidities and their associations with systemic morbidities, among a nationally represen...

"SOS teeth" are defined as the first priority teeth for treatment, that have distinct cavitation reaching the pulp chamber or only root fragments are present. These are teeth with severe morbidity, that may require pulp capping, root canal treatment, or extraction, and therefore should be treated first. The study aims to explore whether or not a me...

Background The stroma of odontogenic cysts/tumors may confer them differential biological behavior. We aimed to investigate the immuno‐expression of stem cell markers (Nanog, SOX2, Oct4, CD34) in the stroma of odontogenic cysts and tumors. CD34 was investigated exclusively as a marker for stromal fibroblast/fibrocyte cells (CD34+SFCs). CD34+SFCs we...

Background: "SOS teeth" are defined as the first priority teeth for treatment, that have distinct cavitation reaching the pulp chamber or only root fragments are present. Objectives: To assess the prevalence and distribution of SOS teeth with regard to age and sex difference among young to middle-aged adults. Methods: This is a cross-sectional...

Objectives: This paper is aimed at addressing the urgent need to develop a protocol that will address the operatory and clinical aspects of dental care during the Coronavirus disease 2019 (COVID-19) outbreak. Data sources: The epidemiology, clinical signs and symptoms, and modes of transmission of COVID-19 are presented. This protocol was establ...

Objectives: To assess and compare dietpractices, body mass index (BMI), and oral health-related quality of life (OHRQoL) in adults with and without periodontitis. Methods: Demographics, health-related behaviors, BMI, dental and periodontal parameters, diet practices, and Oral Health Impact Profile-14 (OHIP-14) were collected from 62periodontitis...

Aims: To test and re-examine the diagnostic criteria for neurovascular orofacial pain (NVOP) compared to posttraumatic trigeminal neuropathy (PTTN). Methods: Pain and patient characteristics were compared in patients with NVOP, PTTN, and NVOP initiated by trauma (PT-NVOP). NVOP criteria were based on prior studies, and PTTN was defined according...

Aims: To analyze cervical tenderness scores (CTS) in patients with various temporomandibular disorders (TMD) and in controls and to examine associations of CTS with demographic and clinical parameters. Methods: This case-control study included 192 TMD patients and 99 controls diagnosed based on a questionnaire and a clinical examination followin...

We retrospectively analyzed the records of patients with mouth dryness who underwent major salivary gland IG in 2013-2015. Major salivary IG glands had been shown as a simple and safe procedure that may relieve dry mouth for a relatively extended duration.

Objectives: To assess the effect of major salivary gland intraductal irrigations (IG) to relieve mouth dryness. Methods: We retrospectively analyzed the records of patients with mouth dryness who underwent major salivary gland IG in 2013-2015. Records included: demographics, medical background, dry mouth etiologies and symptomatology and results...

Objectives To analyze and compare associations between metabolic syndrome (MetS) and its components in periodontitis compared to control patients. Methods This 7‐year cross‐sectional study retrospectively analyzed medical records of 504 individuals aged 18‐90 who attended the student dental clinic between 2008 ‐2014. Demographics, smoking habits,...

Burning mouth syndrome (BMS) is characterized by a spontaneous and chronic sensation of burning in the oral mucosa, with no apparent signs. The underlying pathophysiological and neuropathic mechanisms remain unclear. Here, we attempt to elucidate some of these mechanisms using proteomic profiling and bioinformatic analyses of whole-saliva (WS) from...

Background Researchers demonstrated a correlation between nutrition and health‐related quality‐of‐life (HRQoL). Little is known about the correlation between disorders of nutrition (DON) and Oral HRQoL (OHRQoL). Objectives 1) to measure OHRQoL in DON patients compared to patients attending nutritional counseling for other reasons (e.g. systemic di...

Background The total tenderness score is commonly used in headache practice and contributes valuable information. Objective To assess muscle tenderness scores in patients diagnosed with Temporomandibular disorders (TMD) and analyze their associations with various demographic and clinical parameters. Methods Masticatory (MTS), cervical (CTS) and t...

Aims: To evaluate and compare the pharmacotherapeutic efficacies of two tricyclic antidepressant (TCA) drugs for masticatory myofascial pain (MFP): nortriptyline (NOR) and amitriptyline (AMI). Methods: Fifty patients with chronic MFP were included in the study; 30 were medicated with AMI only, and 20 took NOR after discontinuing AMI due to adver...

Sleep and pain share a bidirectional relationship. Therefore, it is important for practitioners managing patients experiencing either sleep and/or pain issues to recognize and understand this complex association from a neurobiological perspective involving neuroanatomic and neurochemical processes. Accounting for the influence of pain on the variou...

Background: A dental appliance for obstructive sleep apnea (OSA) is recommended for patients who cannot adjust to continuous positive airway pressure (CPAP) treatments. Objectives: To describe patients with extremely severe OSA who were successfully treated with a dental appliance and to compare their characteristics with the relevant literature...

Objectives: To measure dental anxiety levels and oral health-related qualities of life (OHRQoL) in patients with aggressive periodontitis (AgP) compared to controls and analyze their association with various demographic and clinical parameters. Methods: Sixty consecutive patients with AgP were compared to 80 age- and sex-matched controls with no...

Objectives: To examine whether dental anxiety (DA) and oral health-related quality of life (OHRQoL) differ between persons with and those without chronic periodontitis. Methods: One-hundred patients with chronic periodontitis and 50 age- and- sex-matched controls were included. Data were collected on the following: demographics; smoking habits;...

Objective: Patients with Myasthenia gravis (MG) are characterized by muscle weakness that may cause obstructive sleep apnea (OSA). The use of a continuous positive airway pressure (CPAP) device is often needed in order to maintain free breathing during the night and sometimes even during the day. Clinical Presentation: A 29-year-old MG patient is p...

Objective: In this review article, the role of the dentist in the evaluation and treatment of snoring and Obstructive Sleep Apnea Syndrome (OSAS) in children is described. Snoring and OSAS in children is receiving increased awareness, with reported rates approximating 10% of children who regularly snore, and up to 4% who suffer from OSAS. OSAS in...

Premise: Classical trigeminal neuralgia (CTN) and the short-lasting unilateral neuralgiform headache attacks (SUNHA) are clinically similar. Problem: The SUNHAs include short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial aut...

In this review we discuss the management of chronic orofacial pain (COFP) patients with insomnia. Diagnostic work-up and follow-up routines of COFP patients should include assessment of sleep problems. Management is based on a multidisciplinary approach, addressing the factors that modulate the pain experience as well as insomnia and including both...

Objective: Oral appliances (OA) are recommended for patients with severe obstructive sleep apnea who fail to comply with continuous positive airway pressure (CPAP) therapy. This mixed-methods study aimed to quantify adherence to OA therapy and evaluate subjective reasons associated with non-adherence. Materials and methods: The medical records o...

Referral of pain to facial and oral structures is common in neurovascular craniofacial pain (NVCP). Pain quality in NVCP often resembles dental pathologies so dental practitioners often encounter these patients. The commonest NVCPs, migraines and trigeminal autonomic cephalgias (TACs), are classically located around the ocular and frontal regions....

We measured the sleep quality in Temporomandibular Disorders (TMD) patients compared to controls and analyzed its association with various demographic and clinical parameters.

Oral and oropharyngeal cancer is amongst the most common and fatal malignant diseases worldwide, with oral squamous cell carcinomas constitute more than 90% of all lesions. This article follows the oral cancer patient from the point of view of the oral medicine practitioner; from the stage of the potentially malignant disorders to the diagnosis of...

Aims We conducted a cross-sectional study to re-examine the clinical profile of patients with a clinical diagnosis of classical trigeminal neuralgia (CTN). Methods Inclusion criteria consisted of the International Headache Society’s published classification of CTN. For the specific purposes of the study, features such as autonomic signs, persisten...

Aims: We conducted a cohort study to examine demographic and clinical features associated with the pharmacotherapeutic outcome in classical trigeminal neuralgia (CTN) patients. Methods: Patients with a clinical profile indicating a diagnosis of CTN, as per the International Headache Society's published classification, were enrolled prospectively...

AIMS: To measure the oral health-related quality of life (OHRQoL) in patients with temporomandibular disorders (TMD) compared to controls and analyze its association with various demographic and clinical parameters. METHODS: The survey included 187 TMD patients and 200 controls. OHRQoL was measured using the validated Hebrew version of the Oral He...

The aim of the present study was to describe demographic, clinical and pain characteristics of patients in a tertiary orofacial pain clinic.

Dental anxiety and gagging are prevalent problems that severely impact social behavior and quality of life. Due to these similarities and because dental phobia is considered as a Blood-Injection-Injury (B-I-I) phobia, the present study contrasted DA, GAG and control subjects regarding the severity of dental anxiety and investigated the comorbidity...

To measure the oral health-related quality of life (OHRQoL) among young individuals presenting with dental anxiety and exaggerated gag reflex and to compare it to the OHRQoL among young individuals attending restorative dental treatment. Patients with dental anxiety and/or exaggerated gag reflex who were referred to the Department of Oral Medicine...

To evaluate the impact of health-related behaviors and dental attendance on oral health-related quality-of-life (OHRQoL). 192 individuals presenting for dental treatment were included in a cross-sectional survey using a self-administered questionnaire that assessed demographics, smoking and alcohol consumption, physical activity habits, dental atte...

Objective To evaluate the distribution of oral and maxillofacial pathologies (OMFPs) and its association with patient age in young and middle-aged adults.Methods Distribution of histopathologicaly diagnosed OMFPs (N=385) treated during 2007-2010, were recorded and the association with patient age was retrospectively analyzed.ResultsThe main diagnos...

Objective Oral appliances for treating severe obstructive sleep apnea are recommended for patients who failed to comply with continuous positive airway pressure treatment. The objective of this study was to evaluate medium-long-term outcome and success rates of oral appliances in patients with severe obstructive sleep apnea.MethodsA retrospective s...

Purpose: To characterise demographic and clinical parameters among individuals with dental anxiety and exaggerated gag reflex compared to a control group and to analyse the associations between the various parameters. Materials and methods: Sixty-eight patients with dental anxiety and 54 patients with exaggerated gag reflex were compared to a co...

Objectives: To measure the quality and patterns of sleep in dental anxiety and exacerbated gag reflex patients compared to conservative dental treatment (CDT) patients and analyze their association with socio-demographic parameters, specific diagnosis and pain scores. Methods: The survey included 220 patients: 67 patients with dental anxiety, 53...

Background The gold standard for diagnosing oral disease is tissue biopsy. Data regarding compliance with advised oral and maxillofacial (OMF) biopsy are scarce. PurposeTo quantify compliance and evaluate the demographics and clinical factors associated with referrals and compliance with OMF biopsy procedures. Methods Medical records of military pe...

Objective: The aim of this study was to measure the Oral Health Impact Profile-14 (OHIP-14) among young individuals presented with dental anxiety and exacerbated gag reflex compared to young individuals attending conservative dental treatment. Method: All patients with dental anxiety and/or exacerbated gag reflex who were referred to the Medical...

Objectives: To characterize demographic, clinical and serological parameters in recurrent aphthous stomatitis (RAS) patients and analyse their association with serum immunoglobulin E (IgE) levels. Subjects and methods: Forty-nine patients with RAS responded to a questionnaire that included demographic background, stress status, smoking habits, h...

Objectives: To characterize demographic and clinical parameters among individuals with dental anxiety and pronounced gag reflex compared to a control group and analyze the associations between the various parameters. Methods: 68 patients with dental anxiety and 54 patients with pronounced gag reflex were compared to a control group of 200 individ...

To evaluate factors associated with compliance to oral lesions biopsy in young individuals and to measure nature and distribution of histopathological diagnoses of these lesions.

OBJECTIVE: To evaluate the distribution of oral and maxillofacial pathologies (OMFPs) and its association with patient age in young-and middle-aged adults. METHODS: Distribution of histopathologically diagnosed OMFPs (n = 385) treated during 2007–2010 was recorded and the association with patient age was retrospectively analyzed. RESULTS: The main...

Recurrent oral and genital ulceration of Behçet's disease can be very distressing. Usually they are responsive to treatment with topical steroids, local anesthetics, oral colchicine and in severe cases steroids and even immuno-suppressive medications such as azathioprine, methotrexate and thalidomide. We describe a case of Behçet's syndrome in a 48...

It is well documented that oral squamous cell carcinoma (OSCC) is related to risk factors such as smoking and alcohol consumption as well as premalignant lesions and conditions such as leukoplakia, oral lichen planus (OLP), and previous malignancy of the upper respiratory system and gastrointestinal tract. Osseointegrated dental implants are rarely...