Galib Ruknuddin

Galib Ruknuddin
All India Institute of Ayurveda, New Delhi · Rasa Shastra & Bhaishajya Kalpana (Ayurvedic Pharmaceutics)

MD (Ayurveda), PhD

About

225
Publications
294,571
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
1,048
Citations
Additional affiliations
September 2007 - September 2016
Institute of Post Graduate Teaching & Research In Ayurveda
Position
  • Professor (Assistant)
Description
  • Assistant Professor
Education
July 1999 - November 2002
National Institute of Ayurveda
Field of study
  • Ayurveda

Publications

Publications (225)
Article
Full-text available
Aim: The aim of this study was to assess the knowledge, attitude, and practice towards pharmacovigilance for Ayurveda among the teachers and practitioners working in Ayurveda colleges of Gujarat State. Materials and methods: A survey questionnaire with 29 questions covering points like participants' knowledge, attitude and practice towards pharm...
Article
Full-text available
In addition to the efforts of Cabell’s International, Beall’s list of potential predatory journals and publishers, and notification by UGC‑CARE; it is high time to keep a vigilant watch on the possibility of emerging cloning journals in the near future. Although no such cloning has been reported so far in AYUSH systems, it becomes the prime respons...
Article
Full-text available
Tinospora cordifolia (TC) has been reported to prevent hepatotoxicity, whereas other species like Tinospora crispa may be associated with hepatotoxicity. Thus, consumers might develop hepatic injury without correctly identifying the plants that they are consuming. Having proper identification of the source plant becomes a mandate before its use. A...
Article
Respiratory ailments represent over 10% of all disability-adjusted life-years, a statistic that reflects the measure of active and productive life lost owing to a condition. A large number of Confections (Avaleha) have been recommended in various authoritative treatises by ancient seers for different respiratory disorders. Kushmanda Avaleha is one...
Article
Full-text available
Acid peptic disorders are common conditions reported in daily clinical practice in India. Epidemiological study of 30,216 patients inferred 7.8% prevalence of peptic ulcer in India, while prevalence of gastroesophageal reflux is reported to be around 28% in South West India. Repeated gastric ulcers, perforation, or hemorrhage can cause intestinal f...
Article
Full-text available
BACKGROUND: Kajjali (black sulfide of mercury) is prepared with mercury and sulfur as per Ayurvedic classics and is an important ingredient in many Rasaushadhis (herbo-mineral/metallic drugs)/ Ayurvedic medicines. Here, an attempt has been made to understand its chemical composition and microstructure characterization of this drug using AAS/ICP-AES...
Article
Full-text available
BACKGROUND: Kajjali (black sulfide of mercury) is prepared with mercury and sulfur as per Ayurvedic classics and is an important ingredient in many Rasaushadhis (herbo-mineral/metallic drugs)/ Ayurvedic medicines. Here, an attempt has been made to understand its chemical composition and microstructure characterization of this drug using AAS/ICP-AES...
Article
Full-text available
Background: Shelf life is the time period until a product retains its therapeutic attributes and fit for use, consumption, or sale. Every product in this universe has definite shelf life. In Ayurveda texts, shelf life is referred as Saviryata avadhi that is defined as the time period during which the potency (Virya) of any drug remains unaffected....
Presentation
Full-text available
Presented on 10th December 2021
Article
Full-text available
Ayurveda focuses upon preventing and promoting health along with curing of diseases in a systematic way. Ayurvedic literature has numerous single and compound plant-based, herbo-mineral, herbo-metallic formulations for general well being and in disease-specifi c conditions relating to geriatrics. Rasayana is a specialized branch that deals with the...
Presentation
Full-text available
Product processing
Presentation
Full-text available
Concerns on Toxicity of Ayurveda Formulations
Article
Full-text available
Sars Cov-2 has emerged as a global threat worldwide. India has also been severely affected by it and is currently the second worse affected nation. As it is a novel virus, there is no specific treatment strategy as of date. A mild symptomatic case of COVID-19 was managed through Ayurvedic intervention involving a personalized approach based on his...
Article
Full-text available
Bhallataka Taila (Oil) is extracted with the help of Patala Yantra. It is one of the important formulations in Ayurveda pharmaceutics. Shelf life for various dosage forms are described in Ayurveda classics. In the current scenario, the amendment of Rule No. 161-B of the Drugs and Cosmetic Act 1940, specifies the maximum shelf life of Ayurvedic form...
Article
Full-text available
Guduchi ( Tinospora cordifolia [Willd.] Miers) is a flagship rejuvenating herb of Ayurveda with reported anti-diabetic potential. In the present study, different dosage forms of Guduchi stem (growing on neem tree) were developed by adopting Ayurvedic pharmaceutical process of Bhavana (levigation). Guduchi Churna (GC) was subjected to 07 times Bhava...
Article
Full-text available
Context: SARS-CoV-2 is a global public-health concern. Interventions to prevent infection are urgently needed. The anti-inflammatory and antiviral effects of neem make it a potential agent for COVID-19 prophylaxis. Objective: The study intended to evaluate the prophylactic effects of neem capsules for persons at high risk of COVID-19 infection d...
Article
Full-text available
Background Sars Cov-2 has emerged as a global threat since its onset in December 2019. India has also been severely affected by the dreadful Corona Virus and is currently battling one of the worst pandemics of history. WHO and the world medical fraternity are putting their efforts to materialize a treatment or vaccine for this novel virus. A random...
Article
Full-text available
Cell phones have become necessity in all age groups in current scenario. The rate of its use is continuously increasing and is affecting the most energetic group of population i.e. adolescents. India has the highest mobile phone users in the world after Korea. In India among 143 million social media users, 12% are school children. Data related to t...
Article
Full-text available
The role of a physician in health care is pivotal and this has been immensely emphasized in classical literature. The world has recognized the duty of a physician to guide and assure the patients in health-care systems. They treat patients with acute disease, reassure patients with self-limiting disease, managing chronic patients, counsel patients...
Article
Full-text available
Introduction: SARS‐CoV‐2, a global pandemic that caused significant morbidity and mortality worldwide, even in the second wave. Multiple factors influence the disease burden including the vicious circulating virus characteristics, complications, limitations of the existing medicine, aggravation of the disease, and comorbidities in older people. In...
Article
Makaradhwaja is a mercury-based formulation, frequently being used by Ayurveda professionals in the management of various diseases. However, quality and safety concerns are being witnessed in the recent past on these traditional formulations, which are letting down reputation of the system. Thus manufacturing of quality formulations, establishing p...
Article
Full-text available
Introduction: In Ayurveda, metals and minerals are converted into biocompatible forms through specified classical procedures like Shodhana, Marana, etc. before their therapeutic use. Their frequent use without any noticeable side effects since ages is the ultimate proof of safety. But, safety and toxicity concerns are being raised by conventional r...
Article
Full-text available
Background: The word Rasa-sindoor was first mentioned in Rasendra Chintamani. Rasa-sindoor is therapeutically very effective and being indicated in various diseases. It is a mercury- and sulfur-based Rasaushadhis (herbomineral/metallic preparations) prepared by the Kupi Pakva procedure. Here an attempt has been made to prepare and understand its ch...
Article
Full-text available
Introduction: Bhallataka (Semecarpus anacardium L.), commonly known as "marking nut," has vast applicability in indigenous system of medicine and is indicated in many ailments such as skin disorders, tumors and malignant growth, fungal disease, excessive menstruation, vaginal discharge, fever, hemoptysis, constipation, and intestinal parasites. Abo...
Article
Full-text available
Objective: Shelf life is the period during which the potency (Virya) of a drug remains unaffected due to environmental factors or from microbial contamination. Considering the growing popularity of Ayurveda products, it becomes important to maintain the quality of all such products. Shelf life is one of the essential components under quality and ne...
Article
Full-text available
Background: Majority of the population relies on traditional medicines for many of their health related problems. Particularly individuals with chronic illness like diabetes mellitus (DM) are more likely to simultaneously use herbal medicines. Many of such users believe that traditional medicines are natural and therefore safe, but this is a dange...
Article
Full-text available
Background: The concept of Saviryata Avadhi (shelf life) of different Ayurveda dosage forms is well described in Sharngadhara saṃhita. Shelf life is an important component and is mandatory to be displayed on the label of all medicinal products. This is also applicable to Ayurveda; thus, it becomes essential to establish shelf life of formulations t...
Article
Full-text available
Background: Shelf life is the length of time, after which all substances starts to degrade in their qualities and become unsuitable for consumption or sale. Every product has definite shelf life, which depends on various physical, chemical, environmental, and biological factors. Shelf life of various compound formulations was clarified in the class...
Article
Full-text available
Background: Guḍuchi Satva is frequently utilized drug among Ayurvedic physicians for conditions such as Jvara (fever), Daha (burning sensation) and other Pitta predominant conditions. Because of its numerous medicinal attributes, many pharmaceutical companies are manufacturing this formulation. This article is intended to check the difference in or...
Article
Full-text available
Objective: The objective of this study was standardization and Chemical characterization of rasamanikya prepared as per standard operating procedures (SOP) mentioned in the classical text. Methods: Rasamanikya was prepared by putting churnodaka shodhita haratala (Orpiment-As2S3) between two abhraka (white mica) sheets which are heated for a while t...
Article
Full-text available
Background: Laghu Sutashekhara Rasa (LSR) is a herbo mineral formulation containing Shuddha Gairika (Fe2O3) and Shunthi (Zingiber officinale Roxb.) with the levigation of Nagawalli Swarasa (fresh juice of Piper betel Linn.) prepared as per the reference of Rasatarangini Parishistha. This is an important formulation in Ayurveda therapeutics, but it...
Article
Full-text available
Background: Steroidal and non-steroidal anti-inflammatory agents have several limitations, due to which people are moving towards use of traditional medicines. Considering this, the current attempt is aimed to evaluate in vivo anti-inflammatory effect of a poly-herbal formulation Śirīṣāvaleha prepared in presence of water and Kanji (sour gruel). Ka...
Article
Full-text available
Background: To protect the massive trust of patient in Ayurveda, a need aroused for the researches to ascertain the quality, safety & efficacy of herbo-mineral preparations on scientific lines. The rasa-aushadhis are having qualities such as instant effectiveness, requirement in very small dosage and ample therapeutic utility. Mahalaxmi Vilas Rasa...
Article
Full-text available
Background: Swarna Makshika (SM) is a brassy golden yellowish mineral with chemical composition of CuFeS2 that is widely used in therapeutics to treat various disease conditions such as Prameha (diabetes), Panḍu (anemia), Kushtha (skin diseases) and Jwara (fever). This mineral needs to be processed by the following specified Ayurveda guidelines in...
Article
Full-text available
CONTEXT: The different dosage forms of Ayurveda are mostly prepared in the presence of Jala (water) as Drava dravya (extracting medium). Transfer of the medicinal properties of any Dravya (drug) is done on the virtue of Drava dravya (liquid medium). Screening through the classics reveal that seers used Drava such as Kshira (cow's milk), Gomutra (co...
Article
Full-text available
Bhallataka Phala (fruit of Semecarpus anacardium L.), is a well-known anti-hyperlipidaemic drug. Bhallataka is described in all Ayurvedic classics as Rasayana and advocated for various therapeutic purposes such as Kushtha (skin diseases), Arsha (piles), Krimi (worm infestations), Prameha (urine disorders), Medodosha (lipid disorders), etc. Though i...
Article
Full-text available
Introduction: Avaleha (Linctus) is a unique dosage form of Ayurveda that is frequently used in various disorders and as Rasāyana (Immunomodulators). Aṣṭāngavaleha is one such formulation being used for Śvāsa (Asthma), Jvara (Fever), Hikkā (Hiccup) and Kāsa (Cough). Aṣṭāngavaleha has not been mentioned in Brūhattrayī. It had been extensively reviewe...
Article
Full-text available
Rheumatoid arthritis (RA), an auto-immune inflammatory disease is one of the challenging conditions for the physicians to handle due to its chronicity, incurability, complications, morbidity, etc. In spite of potent anti-inflammatory agents and powerful immune-suppressive agents, its prognosis is not good, as these drugs have certain limitations in...
Article
Full-text available
Drugs fulfilling the criterion of a standard drug will always become panacea provided, if they are used properly. On the other hand, a poorly manufactured drug however used skillfully, will prove to be a poison. Texts of Ayurveda, do mention hazards of drugs, which are not properly manufactured or administered. Art of drug administration is unique...
Article
Full-text available
Rasa Shastra is an exclusive branch of ayurveda that uses processed metals and minerals in various combinations. Though the formulations are time tested, safety and quality concerns are being raised since the past two decades. In view of this, it becomes mandatory to generate quality control profiles of such formulations by following available para...
Article
Full-text available
Background: Hyperlipidemia is modifiable risk factor for cardiovascular diseases, and its prevalence is alarmingly increased in India. Although many treatment modalities are effectively used in the conventional system, they have certain limitations and adverse effects. Ayurvedic metallic and herbo-mineral formulations are safely practiced in Indian...
Article
Full-text available
Context: Control of cough remains a major unmet medical need. There is a need to have safe and effective anti‑tussive drug that can alleviate chronic cough without developing side effects. Ashtangavaleha is an effective compound formulation for combating the disease asthma. Aim: The present study was carried out to evaluate anti‑tussive activity of...
Article
Full-text available
Background: Bronchial Asthma is now recognized to be a primarily inflammatory condition. It is an episodic disease manifested clinically by paroxysms of dyspnoea, cough and wheezing. Respiratory diseases are a major cause of disability and poor quality of life. Modern drugs used to treat this condition are known to develop certain adverse reactions...
Article
Full-text available
Background: Herbo‑mineral formulations of Ayurveda contain specified metals or minerals as composition, which have their beneficial effects on biological systems. These metals or minerals are transformed into non‑toxic forms through meticulous procedures explained in Ayurveda. Though literature is available on quality aspects of such herbo‑mineral...
Article
Full-text available
Introduction: Śodhana is a preliminary process that helps in eliminating possible physical or chemical blemishes from raw material and making them suitable for therapeutic application. Guggulu (Commiphora wightii (Arn) Bhandari) is a well-known herb in Āyurveda, which is gaining its attention in world market. Exudate of the plant is therapeutically...
Article
Full-text available
Introduction: Navaka Guggulu is a well-known polyherbal formulation containing Guggulu (Commiphora wightii Arn. Bhandari) as main ingredient. It is effectively used in Medoroga (hyperlipidemia), Sthaulya (obesity), and other Kaphaja roga. In classics, fresh (Naveena) Guggulu is attributed with Brimhana (body mass increasing) effect while old (Puran...
Article
Full-text available
In Ayurveda, Prameha initially mediated through of pathogenesis in DM. Different types of stages of diabetes. Symptoms of beta cell due to deformities in rasayani (channels of nutrition) are mentioned. Aetiopathology of described in a unique way, which emphasize that management should be focused on correction of metabolism at multi systemic level,...
Article
Full-text available
Introduction: Presence of heavy metals (like Mercury, Arsenic, Lead etc.) in Ayurvedic formulations became a major concern in current scenario. Therapeutic use of these formulations since ages without any noticeable side effects is ultimate proof for their safety. Considering the growing concerns, it becomes necessity to prove their safety and effi...
Article
Full-text available
Introduction: Avaleha (linctus) is the secondary dosage form which is widely acceptable and palatable in Ayurvedic system of medicine. In classics, most of the Avaleha are either prepared with sweetening agent like jaggery, sugar or mentioned in the powder form; and are advised to be licked with honey etc. Ashtangavaleha is a herbal formulation men...