Fulya Benzer

• phD
• Professor at Munzur University

Chestnut is a fruit with high carbohydrate content, low-oil ratio and protein content, including minerals, vitamins, amino acids and phenolic compounds which can have antioxidant properties. It has been determined that the amount and composition of phenolic components could change in according to environmental and growing conditions, and the variet...

Van Vet J, 2017, 28 (2) 85-90 Van Veteri nary Jou rnal SUMMARY The effects of enrofloxacin and caffeic acid phenethyl ester (CAPE) alone and in combination applications on the free radical damage and antioxidant system changes occurring in the blood of broilers in Ornithobacterium rhinotracheale (ORT) infection were investigated. For this study, 96...

This study was designed to investigate the effects of dietary kefir on trypsin, heat shock protein 70 (HSP70) as well as the oxidant and antioxidant status of the freshwater crayfish, Astacus leptodactylus . The experiment was performed with the four following treatments: Control group, D 1 , D 2 and D 3 (kefir supplemented diet 2, 4, 8 g/kg of cra...

The polychlorinated biphenyls (PCBs) in aquatic environment adversely affect non-target organisms, including fish. Especially, the male reproduction and next generation can be damaged through high exposure to these pollutants. Hence, the sperm cells were exposed to sublethal concentrations of Aroclor 1254 (0, 1, 5, 10, or 25 mg/l) for 4 h. The sper...

Çalışmada, günümüzde alabalık üretiminde de deniz balıkları üretiminde olduğu kadar kullanımı hızla yaygınlaşan kapalı devre akuakültür sistemi kurulmuştur. Munzur Çayı’ndan temin edilen anaçlardan alınan yumurtalardan çıkan yavru balıkların gelişimi ve antioksidan enzim aktiviteleri araştırılmıştır. Munzur alabalığı yavruları (0,5±0,13 g) proje ka...

Synthetic pyrethroid pesticide is commonly used in agricultural activities in the Black Sea region during reproduction period of turbot. In this sense, in vivo and in vitro studies have shown that cypermethrin (CYP) could be one of the environmental factors affecting decreasing turbot stocks. In this study, effects of in vivo and in vitro administr...

In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and immunohistochemical methods. In the study, rats were given orally at 30 mg/kg/body weight (BW) PbAc after CR of 25 and 50 mg/kg/BW was administered to them orally (a to...

Bu çalışma kurşun asetat (PbA) kaynaklı karaciğer hasarı üzerine chrysinin (CH) etkilerinin araştırılması amacıyla yapıldı. Çalışmada 35 adet Sprague Dawley cinsi erkek rat, her grupta 7 rat olacak şekilde 5 gruba ayrıldı. 1. Grup (Kontrol): Oral yolla serum fizyolojik verildi. 2. Grup (CH grubu): CH (50 mg kg-1 ağırlık gün-1) 7 gün boyunca oral ol...

In the present study, the protective effects of chrysin (CHR) against testicular damage caused by lead acetate (PbAc) were examined. In this way, 30 min after rats were given 25 and 50 mg/kg/b.w CHR orally for seven consecutive days, 30 mg/kg/b.w PbAc was administered orally. In biochemical analysis of testicular tissue, it was found that PbAc‐redu...

Doxorubicin (DXR) is one of the commonly used chemotherapeutic agents, which is highly toxic and causes gastrointestinal and cardiac toxicity. Curcumin is used as a spice and coloring agent in food, but also possesses anti-proliferating, potent antioxidant, antitumor-promoting and anti-carcinogenic properties in vitro and in vivo. In this study, th...

Doxorubicin (DXR) is one of the commonly used chemotherapeutic agents, which are highly toxic to living creatures especially to human because of effects of gastrointestinal and cardiac toxicity. Curcumin (CMN) is widely used spice and coloring agent in food, it possess anti-proliferating, potent antioxidant, antitumor promoting and anti-carcinogeni...

Doxorubicin (DXR) is one of the commonly used chemotherapeutic agents, which is highly toxic and causes gastrointestinal and cardiac toxicity. Curcumin is used as a spice and coloring agent in food, but also possesses anti-proliferating, potent antioxidant, antitumor-promoting and anti-carcinogenic properties in vitro and in vivo. In this study, th...

In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and immunohistochemical methods. In the study, rats were given orally at 30 mg/kg/body weight (BW) PbAc after CR of 25 and 50 mg/kg/BW was administered to them orally (a to...

In this study, Pomegranate (Punica granatum L.), Carob (Ceratonia siliqua L.), Black Mulberry (Morus nigra L.), Mulberry (Morus alba L.) and Grape (Vitis viniera L.) molasses taken from different regions were measured by different methods of antioxidant activity. The radical sweeping power of molasses varieties was determined by DPPH and ABTS metho...

The effects of vitamin E and vitamin E-selenium combination on seminal plasma arginase activity and nitric oxide level and some spermatological properties in rams were investigated in this study. For control group, animals were injected intramuscularly with physiological saline. For vitamin E group, rams were injected intramuscularly with 300 mg/ra...

The purpose of this study is to investigate the effects of L‐arginine on spermato‐logical parameters, seminal plasma nitric oxide levels and arginase enzyme activities. Fertile rams that are 2–3 years old and weighing 50–60 kg were used as material. The semen was collected by artificial vagina at 1st, 4th, 24th, 48th, 72nd, 96th and 120th hours for...

This study was made to investigate the effects of intramuscular administrations of dexamethasone on seminal plasma nitric oxide levels and arginase activity, and some spermatological parameters in rams. Ten Akkaraman rams weighing 50–60 kg and 2 years old were used as material in this study. The study was performed during the breeding season (Septe...

In this study, the antioxidant capacities in flesh fruit, around the apple seeds and peel of apple in five different apple varieties obtained from Eğirdir district of Isparta province was determined by using ABTS, DPPH and TPC methods. When the results of analysis were examined, it was seen that antioxidant levels differed in terms of varieties, pa...

Behaviour and physiology in fish are affected from environmental factors. Particularly, habitat and culture environment in aquatic animals are essential for life stages. In this study, biomarkers of oxidative stress and antioxidant were compared in wild and farmed Çoruh trout (Salmo coruhensis) spermatozoa. In spermatozoa of Çoruh trout, lipid pero...

l-arginine is a versatile amino acid and precursor of nitric oxide that provides protection for preventing free radical damage. Herein, experiments were designed to clarify the effect of l-arginine supplementation on the sperm motility of a threatened trout, Coruh trout Salmo coruhensis. Activation solution was supplemented with levels of 0 mM (Con...

The use of insecticides has been increasing along with increasing agriculture activities and has caused deleterious environmental impacts. Non-target organisms in particular, including fish, are affected by pesticides. In this work, the impacts of cypermethrin (CYP) on sperm oxidative stress markers and sperm motility were investigated in vitro. Th...

The importance of antioxidants having a protective effect against the harmful effects of free radical scavenging cell structure has gradually increased in recent years. Antioxidants are found to high levels in some fruits and wines obtained from these fruits. Several studies have been performed with many fruits and fruit wines containing antioxidan...

The aim of present study was to compare oxidant and antioxidant status of Çoruh trout (Salmo coruhensis), Anatolian trout (Salmo rizeensis) and rainbow trout (Oncorynchus mykiss) spermatozoa. Fish were obtained from Uzungöl. Enzymatic antioxidant activities (superoxide dismutase, catalase, glutathione peroxidase), glutathione and lipid peroxidation...

In this study, effects of hen age and rearing systems on some oxidative stress parameters in serum and ovarian tissues of hens are investigated. For this purpose, total of 48 Bovans White commercial laying hybrids from two different rearing systems (conventional cage and organic) at 30 and 60 weeks of age were used. Serum and ovarian tissues of the...

Doxorubicin (DXR) is a highly effective drug for chemotherapy. However, cardiotoxicity reduces its clinical utility in humans. The present study aimed to assess the ameliorative effect of curcumin against DXR-induced cardiotoxicity in rats. Rats were subjected to oral treatment of curcumin (100 and 200 mg/kg body weight) for 7 days. Cardiotoxicity...

Doxorubicin (DXR) is one of the most important chemotherapeutic agent. However, nephrotoxicity reduces its clinical utility in humans. The aim of the study was to investigate protective effects of curcumin (CMN) against DXR-induced nephrotoxicity. Rats were subjected to oral treatment of CMN (100 and 200 mg/kg body weight) for 7 days. Nephrotoxicit...

The use of pesticides has been increased along with increasing the farming activities and has caused environmental impacts deleteriously. In particular, non-target organisms including fish can be affected by toxic effects of pesticides. Therefore, the impacts of malathion (MTN) on oxidative stress and sperm quality were investigated in vitro. The M...

The use of pesticides has been increasing along with increasing farming activities and has caused deleterious environmental impacts. Non-target organisms in particular, including fish, are affected by pesticides. In this work, the impacts of Chlorpyrifos (CPF) on sperm oxidative stress markers and sperm motility were investigated in vitro. CPF conc...

Van Vet J, 2017, 28 (2) 85-90 Van Veteri nary Jou rnal SUMMARY The effects of enrofloxacin and caffeic acid phenethyl ester (CAPE) alone and in combination applications on the free radical damage and antioxidant system changes occurring in the blood of broilers in Ornithobacterium rhinotracheale (ORT) infection were investigated. For this study, 96...

In the present study was determined the effects of monthly variability on enzymatic antioxidant (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px)), antioxi-dant (reduced glutathione (GSH)) and the oxidant status (nitric oxide (NO), lipid peroxidation (MDA)) in hepatopancreas, muscle, gills and gonad tissues of freshwater...

Stocking density causes changes in behaviour and physiology of aquatic animals and high density can cause oxidative damage in living cells. Therefore, experiments were designed to investigate the effects of stocking density on the oxidant-antioxidant response (glutathione (GSH), glutathione peroxidase (GSH-Px), catalase (CAT), and malondialdehyde (...

The effects of dietary antioxidants (vitamine E, vitamine C, Astaxhantin, β carotene) on arginase activity and nitric oxide levels of hepatopancreas and muscle of freshwater crayfish (Actacus leptodactylus) were investigated during moulting.150 mg kg-1 vitamine E (VE), 200 mg kg-1vitamine C (VC), 200 mg kg-1 Astaxhantin and 200 mg kg-1 β carotene w...

Recent studies have shown that the oxidative state plays an important role in the pathophysiology of neuroinflammatory diseases. Determination of erythrocyte arginase, and catalase (CAT), and also plasma and cerebrospinal fluid (CSF) malondialdehyde (MDA), and nitric oxide (NO) concentrations were measured to establish differences between antioxida...

The aim of this study was to investigate arginase activity, total oxidant capacity (TOC), total antioxidant capacity (TAC), and oxidative stress index (OSI) in cows with lung cystic echinococcosis (CE). The subjects were 20 cows with lung CE (parasitized group) and 20 healthy cows (control group). A significant increase in arginase activity, TOC, a...

Gentamicin is commonly used against gram-negative microorganisms. Its therapeutic use is mainly limited by nephrotoxicity. This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity in rats. The rats were treated with saline intraperitoneally (group I), 150...

Gentamicin is commonly used against gram-negative microorganisms. Its therapeutic use is mainly limited by nephrotoxicity. This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity in rats. The rats were treated with saline intraperitoneally (group I), 150...

This study examined the effects of orally given pomegranate seed extract (PSE) on healing of surgically induced full thickness skin wounds in terms of clinical, histopathological and biochemical aspects. A total of 48 healthy, adult male New Zealand rabbits were randomly divided in 2 equal experimental (PSE group) and control groups (C): one week p...

The most important primary headaches are migraine. Migraine has a prevalence of 10% in the general population and its societal costs are high. The precise mechanisms underlying the pathophysiology of migraine are still elusive. Nitric oxide (NO) is believed to play a key role in migraine pathogenesis. In this study, we compared migraine patients wi...

The aim of this study was to determine whether antioxidant pomegranate seed extract (PSE) has a preventive effect on cisplatin-induced hepatotoxicity. Rabbits were divided into 3 groups (n=6):1—Control group (0.9 % saline. i.p) 2—Cisplatin group (a single dose of cisplatin (5 mg/kg, i.p) 3— A single dose of cisplatin (5 mg/kg, i.p) + PSE (250 mg/kg...

The objective of the present work was to examine the effects of different doses (0, 10, 20 and 40 g kg -1 fish diet mass) of kefir on growth performance and oxidant-antioxidant status in the blood and liver tissues of Coruh trout, Salmo coruhensis, in different periods (2 and 3 months). In this study, survival was more than 88.3%, and irrespective...

This study examined the effects of orally given grape seed extract (GSE) on healing of surgically induced full thickness skin wounds in terms of clinical, histopathological and biochemical aspects. A total of 48 healthy, adult male New Zealand rabbits were randomly divided in 2 equal experimental and control groups: one week prior the surgery, 260...

Cited By (since 1996):1, Export Date: 18 October 2014

Cisplatin (CP) is one of the most effective cancer chemotherapeutic agent used against various solid tumors. This study was designed to investigate the antioxidant effects of Grape Seed Extract (GSE) on CP induced oxidative damage in rabbit kidney. The material of study was consist of 18 male New Zealand rabbit. Animals were divided into 3 groups....

The aim of this study is to evaluate the protective effect of pomegranate seed extract on cisplatin-induced oxidative stress in rabbits testes. Rabbits were divided into three groups; (i) being control group, (ii) cisplatin group and (iii) cisplatin + pomegranate seed extract group. The level of malondialdehyde and glutathione, the activity of cata...

The aim of the present study was to investigate the plasma nitric oxide concentrations and the erythrocyte arginase activities in lambs with contagious ecthyma, which frequently occurs in lambs and goat kids. The study was conducted on 10 Akkaraman, 1-2 month old lambs with contagious ecthyma (the clinical diagnosis was based on the presence of typ...

Curcumin, a widely used spice and colouring agent in food, has been shown to possess potent antioxidant, antitumor promoting and anti-inflammatory properties in vitro and in vivo. The present study was designed to investigate the protective effects of curcumin on changes in the levels of lipid peroxidation and endogenous antioxidants induced by cis...

Biological compounds with antioxidant properties may contribute to the protection of cells and tissues against deleterious effects of reactive oxygen species (ROS) and other free radicals induced by cisplatin. This study was performed to investigate the possible protective role of antioxidant treatment with grape seed extract (GSE) on cisplatin-ind...

Aim of this study was to determine the extent of pollution in the Munzur River in Turkey was determined. The antioxidant (reduced glutathione (GSH), glutathione peroxidase (GSH-Px) catalase (CAT)) and the oxidant (MDA) status of hepatopancreas, gills, muscle, heart and kidney tissues of C. trutta were chosen as bioindicators. The fish samples were...

The objective of the study was to characterize the effects of sex on lipid peroxidation (as malondialdehyde, MDA), antioxidant defence system (as glutathione peroxidase, GSH-Px) in the hepatopancreas, gonad and muscle tissues of freshwater crayfish, Astacus leptodactylus, in culture condition. The crayfish used in the present study was provided fro...

Heavy metal pollution of waters is a major environmental problem. Due to their toxicity, long persistence, bioaccumulative and nonbiodegradable properties in the food chain, heavy metals constitute a core group of aquatic pollutants. Capoeta trutta is an economically important fish and the object of significant commercial fishery in the Munzur Rive...

The purpose of this study was to macroscopically and histopathologically evaluate the healing of a surgically induced full thickness wound in rats fed with a diet enriched in whey proteins, and to locally analyze the oxidant/antioxidant status. A total of 50 female Wistar albino rats were randomly allotted in 2 equal groups (n = 25) according to th...

The aim of this study was to investigate the effects of fresh, ensiled and dried alfalfa on the meat quality of lamb. For this purpose, 40 Akkaraman, 4 months old, lambs were divided into 4 equal groups according to the dietary treatments: control lambs were fed with wheat straw whereas the ration of all other animals were based on alfalfa in a fre...

Pregnancy is a condition that favours oxidative stress. The aim of this study was to evaluate the oxidant and antioxidant status by measuring glutathione peroxidase (GSH-Px), catalase (CAT) activities and malondialdehyde (MDA) and glutathione (GSH) concentrations before and during pregnancy in ewes. Twelve healthy female and two healthy male Awassi...

This experiment was conducted to evaluate the effects of Ornithobacterium rhinotracheale (ORT) infection on oxidative stress and the activity of antioxidant enzymes in blood, trachea and lung tissues of broilers. Broiler chickens were divided into 2 groups, each consisting of 30 animals. Group 1 was used as control group; Group 2 was used as infect...

The effects of dietary intake of vitamin E and selenium on aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities in rats treated with high doses of prednisolone were investigated. Rats were divided into 5 groups. Groups 3, 4 and 5 received a daily supplement in their drinking water of 20 mg vitamin E, 0.3 mg Se and a combin...

The aim of this study was to investigate the antioxidant (reduced glutathione (GSH), glutathione peroxidase (GSH-Px)) and the oxidant (nitric oxide (NO), lipid peroxidation (MDA)) status of hepatopancreas, gills and muscle tissues of freshwater crayfish (A. leptodactylus) collected from the Keban Dam Lake and to evaluate the effect of aquatic pollu...

Oxygen free radicals generated in biological systems by cigarette smoke (CS) inhalation can cause oxidative stress in tissues, resulting in lipid peroxidation. To investigate whether cigarette smoking at different periods affect peroxidation speed, we examined concentrations of malondialdehyde (MDA) and activities of the catalase (CAT) and arginase...

No comparative studies have addressed the oxidant and antioxidant states of blood and cerebrospinal fluid. To reveal this differential state, the study was designed to identify the seizure type with the worse prognosis by determining erythrocyte arginase and erythrocyte catalase, plasma and cerebrospinal fluid malondialdehyde, and plasma and cerebr...

ZET Bu çalışma, yüksek dozda gentamisin verilen ratlarda manganez klorür (MnCl 2)'ün karaciğer ve böbrek arginazı üzerine etkilerini araştırmak amacıyla yapıldı. Erişkin 36 adet Wistar Albino rat 6 eşit gruba ayrıldı. Birinci grup kontrol, ikinci gruba tek başına gentamisin (gentamisin sülfat 100 mg/kg, i.p.), üçüncü ve dördüncü gruplara tek başına...

ZET Zorunlu hücre içi patojenleri olan klamidialar patojenik mekanizmaları tam olarak bilinmeyen pek çok hastalığa sebep olurlar. Bir veya daha fazla ortaklanmamış elektron içeren atom veya moleküller olan serbest radikaller aktive olmuş fagositlerin bakterisidal rollerinin sonucunda üretilirler. Hücre bütünlüğünü tehdit eden en önemli sorunlardan...

Free radicals are now well known to damage cellular components. To investigate whether age and thyroid level affect peroxidation speed, we examined the levels of malondialdehyde and antioxidant enzyme activities in different age groups of hypothyroid rats. Hypothyroidism was induced in 30- and 60-day-old Wistar Albino rats by the i.p. administratio...

In this study, the levels of malondialdehyde and activities of catalase and glutathione peroxidase, two antioxidant enzymes, and the levels of nitric oxide in sheep infected with Fasciola hepatica were measured. The level of malondialdehyde in plasma and tissue was measured according to the Yagi and Ohkawa methods, respectively. The activities of c...