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Publications (26)
In einer Studie mit 12 gesunden Probanden evaluierten wir ein EEG-Verarbeitungssystem zur Echtzeitphasendetektion, das auf Grundlage eines kurzlich vorgestellten EEG-Aufnahme-Gerats von uns entwickelt wurde [1]. Ziel der Studie war es, mittels paralleler Aufnahmen mit einem konventionellen EEG-System die Gute der Echtzeitphasendetektion zu prufen....
Neuromuscular stimulation has been used as one potential rehabilitative treatment option to restore motor function and improve recovery in patients with paresis. Especially stroke patients who often regain only limited hand function would greatly benefit from a therapy that enhances recovery and restores movement. Multiple studies investigated the...
Modern neuroimaging techniques, such as structural and functional magnetic resonance imaging (MRI) and non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) are increasingly used in the neuroscientific research of neurological disorders, such as stroke, tinnitus and movement disorders. These methods offer a non-...
Brain-Machine Interfaces (BMI) allow manipulation of external devices and computers directly with brain activity without involvement of overt motor actions. The neurophysiological principles of such robotic brain devices and BMIs follow Hebbian learning rules as described and realized by Valentino Braitenberg in his book "Vehicles," in the concept...
Introduction: Local phase information of oscillatory activity has been shown to reflect different states of brain activity and is thought to play a crucial part in human brain information processing. In the visual system, phase properties of parieto-occipital alpha band oscillations were associated with perception and perception thresholds respecti...
Despite the fact that premonitory urges precede most tics in patients with Gilles de la Tourette syndrome (GTS), the voluntariness of tic elicitation and its suppressibility as a response to these urges still remains unclear. Moreover, there are no systematic studies examining the association between urge intensity and the ability to suppress tics....
Cortical reorganization within the primary motor cortex (M1) contralateral to a practicing hand has been extensively investigated. The extent to which the ipsilateral M1 participates in these plastic changes is not known. Here, we evaluated the influence of unilateral hand practice on the organization of the M1 ipsilateral and contralateral to the...
This article explains the role of brain stimulation in neurorehabilitation. The outline of this article is formed by the characterization of some of the problems faced in the field of nuerorehabilitation. Furthermore, it describes results of studies conducted to understand the functional changes in the motor cortices of hemispheres after stroke. Th...
Noninvasive brain stimulation has developed as a promising tool for cognitive neuroscientists. Transcranial magnetic (TMS) and direct current (tDCS) stimulation allow researchers to purposefully enhance or decrease excitability in focal areas of the brain. The purpose of this paper is to review information on the use of TMS and tDCS as research too...
Noninvasive brain stimulation has developed as a promising tool for cognitive neuroscientists. Transcranial magnetic (TMS) and direct current (tDCS) stimulation allow researchers to purposefully enhance or decrease excitability in focal areas of the brain. The purpose of this paper is to review information on the use of TMS and tDCS as research too...
The lumbar puncture is performed by inserting a needle into the spinal chord of the patient to inject medicaments or to extract
liquor. This procedure is usually trained on the patient guided by experienced supervisors. A virtual reality lumbar puncture
simulator has been developed in order to enhance the training by providing new insight into a vi...
TMS wird seit weit über 15 Jahren in der Neurologie zur Routinediagnostik der Leitfähigkeit motorischer Bahnen eingesetzt. Bei Schlaganfallpatienten hat sie vor allem prognostischen Wert in der Abschätzung noch vorhandener kortikospinaler Bahnen (Kap. 24). Die therapeutischen Möglichkeiten der TMS hingegen werden zwar oft als “erfolgsversprechend„...
Successful music performance requires adequate contextual control of behaviour, that is, the retrieval and non-retrieval, or inhibition, of learned actions. This chapter describes recent advances in the understanding of neural correlates of controlling motor behaviour, as identified with transcranial magnetic stimulation (TMS), electroencephalograp...
Purpose: In a previous study, a temporary upregulation of interhemispheric functional coupling (measured as EEG coherence) has been identified as a correlate of bimanual motor learning (Andres et al. Brain 1999; 122, 855–70). Here, we tested the hypothesis that the posterior parietal cortex (PPC) serves as a cortical „driver“ that modulates interhe...
The effects of a single oral dose of levodopa administered in a randomized, double-blind, placebo-controlled cross-over design on formation of a motor memory were studied by a training protocol in patients with chronic stroke. Levodopa enhanced the ability of motor training to encode an elementary motor memory relative to placebo. Up-regulation of...
The ability of the central nervous system to form motor memories, a process contributing to motor learning and skill acquisition, decreases with age. Dopaminergic activity, one of the mechanisms implicated in memory formation, experiences a similar decline with aging. It is possible that restoring dopaminergic function in elderly adults could lead...
Plasticity is the ability of the central nervous system (CNS) to adapt to environmental challenges or to compensate for lesions.²⁹ This definition assumes that the CNS can identify changes in the environment relevant to the individual, process this information, and generate appropriate behavioral responses. Until recently, it was thought that the b...
Brain activity elicited by visually presented words was investigated using behavioral measures and current source densities calculated from high-resolution EEG recordings. Verbs referring to actions usually performed with different body parts were compared. Behavioral data indicated faster processing of verbs referring to actions performed with the...
Neurophysiological brain responses to subcategories of action verbs were recorded using high resolution EEG. Starting 240 ms after word onset, topographies of event-related potentials distinguished between verbs referring to different action types. Current source density estimates revealed that verbs referring to actions executed with the legs (to...
