Friederike Holderried

Friederike Holderried
University of Tübingen | EKU Tübingen · Faculty of Medicine

Doctor of Medicine
Head of "TIME Innovation Hub" Medical faculty Tübingen

About

44
Publications
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564
Citations

Publications

Publications (44)
Preprint
BACKGROUND For hospitalized patients, the discharge letter is an important source of medical information, containing numerous discharge instructions and health care tasks for the patients to manage their own health. However, it is usually written in professional jargon that is inaccessible to patients with little medical knowledge. Large language m...
Article
Background For hospitalized patients, the discharge letter serves as a crucial source of medical information, outlining important discharge instructions and health management tasks. However, these letters are often written in professional jargon, making them difficult for patients with limited medical knowledge to understand. Large language models,...
Article
Full-text available
Objective The usage of digital information and communication technologies in European healthcare is growing. Unlike numerous technological possibilities, the present use of these technologies and perspectives towards them in relation to otolaryngology care have so far been of less interest. This study evaluates the utilisation of and attitudes towa...
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Background Although history taking is fundamental for diagnosing medical conditions, teaching and providing feedback on the skill can be challenging due to resource constraints. Virtual simulated patients and web-based chatbots have thus emerged as educational tools, with recent advancements in artificial intelligence (AI) such as large language mo...
Preprint
BACKGROUND Although history taking is fundamental for diagnosing medical conditions, teaching and providing feedback on the skill can be challenging due to resource constraints. Virtual simulated patients and web-based chatbots have thus emerged as educational tools, with recent advancements in artificial intelligence (AI) such as large language mo...
Article
Background Large language models such as GPT-4 (Generative Pre-trained Transformer 4) are being increasingly used in medicine and medical education. However, these models are prone to “hallucinations” (ie, outputs that seem convincing while being factually incorrect). It is currently unknown how these errors by large language models relate to the d...
Article
Background Communication is a core competency of medical professionals and of utmost importance for patient safety. Although medical curricula emphasize communication training, traditional formats, such as real or simulated patient interactions, can present psychological stress and are limited in repetition. The recent emergence of large language m...
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Full-text available
BACKGROUND Communication is a core competency of medical professionals and of utmost importance for patient safety. Although medical curricula emphasize communication training, traditional formats, such as real or simulated patient interactions, can present psychological stress and are limited in repetition. The recent emergence of large language m...
Preprint
BACKGROUND Large language models such as GPT-4 (Generative Pre-trained Transformer 4) are being increasingly used in medicine and medical education. However, these models are prone to “hallucinations” (ie, outputs that seem convincing while being factually incorrect). It is currently unknown how these errors by large language models relate to the d...
Preprint
Full-text available
Introduction: Large language models (LLMs) such as GPT-4 are increasingly used in medicine and medical education. However, these models are prone to "hallucinations" - outputs that sound convincing while being factually incorrect. It is currently unknown how these errors by LLMs relate to the different cognitive levels defined in Bloom's Taxonomy....
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Introduction In ever changing conditions, medical faculties must face the challenge of preparing their medical students as best as possible for the demands of their future work. This requires involving all stakeholders, especially medical students in the constant redefinition of medical curricula. Using the idea of “Communities of Practice” as conc...
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Background Language barriers in medical encounters pose risks for interactions with patients, their care, and their outcomes. Because human translators, the gold standard for mitigating language barriers, can be cost- and time-intensive, mechanical alternatives such as language translation apps (LTA) have gained in popularity. However, adequate tra...
Preprint
BACKGROUND Language barriers in medical encounters pose risks for interactions with patients, their care, and their outcomes. Because human translators, the gold standard for mitigating language barriers, can be cost- and time-intensive, mechanical alternatives such as language translation apps (LTA) have gained in popularity. However, adequate tra...
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Situations like the COVID-19 pandemic urgently require the implementation of eHealth for vulnerable patient populations. Here we quantitatively evaluate use and potential of modern information and communication technology (ICT) in solid organ transplant (SOT) recipients. We conducted a structured, questionnaire-based, cross-sectional study that was...
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Chart review is an important tool to identify patient hazards. Most advanced medical students perform poorly during chart review but can learn how to identify patient hazards context-independently. Many hospitals have implemented electronic health records, which enhance patient safety but also pose challenges. We investigated whether electronic cha...
Chapter
Moderne Informations- und Kommunikationstechnologien (IKT) sind zunehmend integraler Bestandteil in unserem alltäglichen Leben. Damit einhergehend und für die Nutzer nahezu unbemerkt steigen Quantität und Qualität an digitalen Informationen als Basis für maschinelles Lernen und die künstliche Intelligenz. Auch in der Medizin nehmen Vielfalt und Nut...
Preprint
BACKGROUND Electronic Health Records (EHR) are used widely for state of the art co-working on patient cases within multidisciplinary hospital teams. Therefore, medical students need to be trained for using health information technologies within this environment from the early stages of their education on. OBJECTIVE As little is known about the eff...
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Background: An electronic health record (EHR) is the state-of-the-art method for ensuring all data concerning a given patient are up to date for use by multidisciplinary hospital teams. Therefore, medical students need to be trained to use health information technologies within this environment from the early stages of their education. Objective:...
Chapter
Sektorenübergreifend wird der Bedarf wachsen, die organisationsinterne Prozesstransparenz und Innovationskompetenz der Gesundheitsdienstleister kontinuierlich zu verbessern, um Optimierungspotenziale für die Verbesserung von Qualität, Sicherheit und Wirtschaftlichkeit unternehmensintern zu generieren. Das Teamlernen basierend auf Performance Measur...
Article
Background: Despite the high importance of communicative and clinical-practical skills for practicing medicine, the examination format named Objective Structured Clinical Examination (OSCE) has also been established at the medical faculties in Germany. Objectives: Due to the 10th anniversary of Tübingen OSCE, this article aimed to outline and ana...
Article
Introduction: Online communication and the number of e-health applications have noticeably increased. However, little is known about the otolaryngologists' use behavior and their attitudes toward the potential of e-health. The aims of the study were to evaluate the documentation, information, and communication technologies used by otolaryngologist...
Chapter
Seit einigen Jahren ist eine zunehmende Digitalisierung der Dokumentation und Kommunikation von medizinischen Informationen in stationären Gesundheitseinrichtungen zu beobachten. Vielerorts werden auf spezielle medizinische Fachbereiche oder konkrete Anwendungsbereiche spezialisierte Softwaresysteme implementiert, die aufgrund ihres hohen Spezialis...
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The use of modern information and communication technologies (ICT) in daily life has significantly increased during the last several years. These essential online technologies have also found their way into the healthcare system. The use of modern ICT for health reasons can be summarized by the term ‘eHealth’. Despite the potential importance of eH...
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Background Communication skills are essential in a patient-centred health service and therefore in medical teaching. Although significant differences in communication behaviour of male and female students are known, gender differences in the performance of students are still under-reported. The aim of this study was to analyse gender differences in...
Article
Um die 10-20 % der deutschen Bevölkerung leiden an Kopfschmerzen, dies entspricht etwa 12 Millionen Betroffenen allein in Deutschland. Die häufigsten Kopfschmerzformen sind Spannungskopfschmerz und Migräne. Am Anfang der Kopfschmerzdiagnostik sollte immer eine strukturierte und sorgfältige Anamnese stehen, die dem geübten Diagnostiker manchmal bere...
Article
Approximately 12 million people or 10-20 % of the German population suffer from headaches. The most common types are tension headaches and migraines. A structured and thorough headache history allows the physician to recognise a pattern and to categorise the headache type. But this can be challenging as headache patients are often in pain, depresse...
Article
Recent age-projection showed that the number of elderly is expected to rise significantly over the next decades worldwide. Accordingly, the prevalence of chronic and degenerative diseases will increase, among them osteoarthritis, resulting in more and older patients undergoing total joint arthroplasty and thereby also being at risk for associated c...
Article
A change in German licensing legislation imposed a portfolio for surgical clerks. We aimed to analyze whether the implementation of the portfolio changed the amount of clinical exposure and activities during surgical clerkships. The study was conducted with a modified pre-post design at the University Hospital of Tuebingen, Germany. Before and afte...
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Patient chart review is the gold standard for detection of potential patient hazards (i.e. medication errors or failure to follow up actionable results) in both routine clinical care and patient safety research. However, advanced medical students' ability to read patient charts and to identify patient hazards is rather poor. We therefore investigat...
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Full-text available
Background Informed consent talks are mandatory before invasive interventions. However, the patients’ information recall has been shown to be rather poor. We investigated, whether medical laypersons recalled more information items from a simulated informed consent talk after advanced medical students participated in a communication training aiming...
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During internships most medical students engage in history taking and physical examination during evaluation of hospitalized patients. However, the students' ability for pattern recognition is not as developed as in medical experts and complete history taking is often not repeated by an expert, so important clues may be missed. On the other hand, s...
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Hospital doctors face constantly increasing workloads. Besides caring for patients, their duties also comprise the education of future colleagues. The aim of this study was to objectively investigate whether the workload arising from increased patient care interferes with student supervision and is associated with more non-medical activities of fin...
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The feminization of the medical profession, demographic change with an impending shortage of physicians, Generation Y - these issues are new challenges for medical schools in terms of their social responsibility and the training of the next generation of highly qualified scientists. This study, conducted by the University Hospital of Ulm throughout...
Article
The protein polymorphism of the GH receptor caused by genomic deletion of exon 3 (d3) has been linked to the magnitude of the first-year-growth response to GH in girls with Turner syndrome. Here, we studied the long-term effect of GH therapy in Turner syndrome in correlation to this polymorphism. The study was mainly retrospective. The women with T...
Article
A protein polymorphism of the GH receptor (GHR) based on the genomic deletion of exon 3 (d3-GHR) has recently been linked to the magnitude of growth response to high-dose recombinant human GH (rhGH) therapy of short children without GH deficiency. This study tests the novel association in two distinct groups of rhGH-treated patients, short girls wi...

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