Frederik Feys

Frederik Feys
Vrije Universiteit Brussel | VUB · Family Medicine and Chronic Care

MSc, PhD

About

43
Publications
14,066
Reads
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225
Citations
Additional affiliations
September 2011 - November 2015
Vrije Universiteit Brussel
Position
  • PhD Student
Education
September 2003 - June 2004
University of Antwerp
Field of study
  • Academic teacher training
September 2001 - June 2003
KU Leuven
Field of study
  • Sexology
September 1997 - June 1998
KU Leuven
Field of study
  • Medicine

Publications

Publications (43)
Article
Full-text available
Studies suggest that expectations powerfully shape clinical outcomes. For subjective outcomes in adequately blinded trials, health improvements are substantial and largely explained by non-specific factors.The objective of this study was to investigate if unblinding in randomized controlled trials (RCTs) is associated with enhanced placebo effects...
Article
Full-text available
Background: Recently, dapoxetine was approved by the European Medicines Agency (EMA) as an effective and safe pharmacological agent for the treatment of premature ejaculation (PE). The objective of this study was to systematically review the efficacy and harm of dapoxetine. Methods: We included randomized controlled trials that investigated the ef...
Article
Full-text available
Importance In August 2015, the US Food and Drug Administration (FDA) approved flibanserin as a treatment for hypoactive sexual desire disorder (HSDD) in premenopausal women, despite concern about suboptimal risk-benefit trade-offs.Objective To conduct a systematic review and meta-analysis of randomized clinical trials assessing efficacy and safet...
Preprint
Full-text available
OBJECTIVE Immunological mind-body research suggests mental health may also be important in the COVID-19 pandemic. This study aimed to investigate the potential influence of mental health as a protective factor for COVID-19 related mortality in the general population. METHODS Data sources were the Global Burden of Disease report 2017 and publicly re...
Article
Full-text available
OBJECTIVE The objective of this study was to assess the benefits and risks of a lockdown in Belgium, with focus on mental health. Consequently, projecting the cost effectiveness of remedial measures. METHODS For benefits; in estimating health savings, we compared Belgium (lockdown) and Sweden (lockdown-light) for COVID-19 related deaths, peak inten...
Research
Full-text available
In this pilot-study, we want to evaluate to what degree niacin is a good active placebo for blinding side-effects of sildenafil. If recruitment allows, we'll test if subjects after ingesting one passive placebo pill already have enough cues to guess their group allocation better than subjects in the sildenafil arm. For this, we'll add a third passi...
Article
Full-text available
Background Patients’ expectations of treatment effects may contribute to positive (placebo) and negative (nocebo) outcomes. The effect of patient expectations may be pronounced in subjectively assessed conditions, such as male erectile dysfunction. The aim of this project is to examine the magnitude of expectancy in trials of phosphodiesterase-5 in...
Article
Full-text available
Studies rond antidepressiva wijzen erop dat de farmacologische werkzaamheid bij vergelijking met een actief placebo veel geringer uitvalt dan bij vergelijking met een passief placebo. Dit is mogelijkerwijs ook het geval bij veel andere types van geneesmiddelen. Dit zou op zich enorme gevolgen kunnen hebben voor de geloofwaardigheid van medicatie en...

Questions

Questions (13)
Question
Hi everyone !
Norway population is 5,432,580 I am confused how to implement the assumption "20% of people infectious with SARS-CoV-2 do not have symptoms".
What is the formula used to get the number of masks needed to wear to prevent 1 infection?
Thank you for your time
Frederik
Question
Hello everyone
Who is expert in discovering confounding? We just wrapped up preliminary work on the possible association between psychological well-being and covid-19 survival. We found a weak link.
However, what confounding do you think might be at play?
Deleted research item The research item mentioned here has been deleted
Happy to discuss
Frederik
Question
Hi everyone
I modeled using a uni-variate regression.This is a plot of fitted versus residual values. Clearly this model violates the assumption of normality. What could be going on?
Thank you
Frederik
Question
Hi everyone,
The world is in crisis; scientific communities work to their best to find answers. From our side, we worked on a risk assessment for the lockdown strategy, focusing on psychological well-being.
We submitted to medrxiv and this was the shocking reality:
medrxivpreprint censored our manuscript because "the work challenges a widely accepted public health measure".
What do you think? Isn't challenging work what drives science forward? Questioning existing paradigms; admit knowledge gaps and improve to make progress ...
Lets discuss this,
Deleted research item The research item mentioned here has been deleted
Question
I get this weird error. A rather basic action to add your data (spreadsheet file) to a preprint manuscript...? How to do this?
Thanks
Frederik
Question
Hello everyone!
A standard approach after the diagnosis of leukemia is immunosuppression and later on transplantation of donor cells.
A doctor may state that "if we do not start therapy immediately, you (the patient) will die within weeks."
What evidence is there for this statement? What research exists that studies no intervention (watchful waiting)?
Thank you
Question
Hi Everyone,
I want to analyse how well two scales agree for detecting changes in wellbeing. I look at the Bland-Altman Method. One scale is a simple score from 0 - 10 for wellbeing. The other scale is the well established Beck’s Depression Inventory-II (goes from 0 - 63) . I wonder how to analyse the agreement?
Thanks!
Fred
Question
Hi everyone!
I have a 2 repeated measures that was asked at 3 moments in time (within-subject factor). We doubled the measure to control for response bias. So the measure (likert scale) probed the same topic but one time positively framed ("did this help you?" and another negatively framed ("did this hinder you?").
I use a GLM repeated measures strategy to analyse. How to put the 2 measures into the same model? Do I add the hindered measures as a covariate? Please see screenshot for more.
Thanks for helping me out!!
Fred
Question
Hi everyone!
I am stuck with a seemingly very simple logistic regression analysis. What is the impact of diabetes(nominal var, values 0-1) on preterm birth (nominal var, values 0-1)? In the output, the Nagelkerk is < .00. Weird, since the expected coefficient (Exp (B) is 1.77. To wich I conclude, that diabetes increases the risk with 77% for preterm birth. I would expect the Nagelkerk to be around .30 or so? Am I doing this analysis correctly? Any input very much welcome!
Thanks
Fred

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