Frank Edward Nelson

Temple University | TU · Department of Biology

Simple matrix sampling planned missing (SMS PD) design, introduce missing data patterns that lead to covariances between variables that are not jointly observed, and create difficulties for analyses other than mean and variance estimations. Based on prior research, we adopted a new multigroup confirmatory factor analysis (CFA) approach to handle mi...

The Inference-Making and Reasoning in Biology (IMRB) measure is an assessment tool intended to 1) aid university personnel in advising students on course enrollment, 2) identify students in need of interventions to increase their reasoning skills and likelihood of completing STEM majors, 3) support instructors in determining growth in students’ rea...

Making inferences and reasoning with new scientific information is critical for successful performance in biology coursework. Thus, identifying students who are weak in these skills could allow the early provision of additional support and course placement recommendations to help students develop their reasoning abilities, leading to better perform...

The purpose of this study was to explore the use of water quality parameters as proxy variables for establishing a timeline for the postmortem submersion interval (PMSI). This research was conducted using mice in water samples collected from the Schuylkill river in Philadelphia, US, as well as deionized water for control. Parameters were monitored...

Reasoning skills have been clearly related to achievement in introductory undergraduate biology, a course with a high failure rate that may contribute to dropout of undergraduate STEM majors. Existing measures are focused on the experimental method, such as generating hypotheses, choosing a research method, how to control variables other than those...

Type I males of the Pacific midshipman fish ( Porichthys notatus ) vibrate their swimbladder to generate mating calls, or “hums,” that attract females to their nests. In contrast to the intermittent calls produced by male Atlantic toadfish ( Opsanus tau ), which occur with a duty cycle (calling time divided by total time) of only 3–8%, midshipman c...

Muscle produces force by forming cross bridges, using energy released from ATP. While the magnitude and duration of force production primarily determine the energy requirement, nearly a century ago Fenn observed that muscle shortening or lengthening influenced energetic cost of contraction. When work is done by the muscle, the energy cost is increa...

The mating call of the Atlantic toadfish is generated by bursts of high-frequency twitches of the superfast twitch fibers that surround the swimbladder. At 16°C, a calling period can last several hours, with individual 80-100-Hz calls lasting ∼500 ms interleaved with silent periods (intercall intervals) lasting ∼10 s. To understand the intracellula...

Can human muscle be highly efficient in vivo? Animal muscles typically show contraction-coupling efficiencies <50% in vitro but a recent study reports that the human first dorsal interosseous (FDI) muscle of the hand has an efficiency value in vivo of 68%. We examine two key factors that could account for this apparently high efficiency value: (1)...

Little is known about how in vivo muscle efficiency, that is the ratio of mechanical and metabolic power, is affected by changes in locomotory tasks. One of the main problems with determining in vivo muscle efficiency is the large number of muscles generally used to produce mechanical power. Animal flight provides a unique model for determining mus...

Animals commonly move over a range of speeds, and encounter considerable variation in habitat structure, such as inclines. Hindlimb kinematics and muscle function in diverse groups of vertebrates are affected by these changes in behavior and habitat structure, providing a fruitful source of variation for studying the integration of kinematics and m...

At most joints, there is a redundancy of muscle function. For any given movement, there are a wide range of possible solutions to the problem of how force is shared among muscle synergists. A better understanding of how force is shared among muscle synergists can provide insight into the mechanics and control of movement. We examined force sharing...

The force-velocity properties of skeletal muscle have an important influence on locomotor performance. All skeletal muscles produce less force the faster they shorten and typically develop maximal power at velocities of approximately 30% of maximum shortening velocity (V(max)). We used direct measurements of muscle mechanical function in two ankle...

We examined the length changes and electromyographic (EMG) activity of two hindlimb muscles in wild turkeys, to determine how these muscles modulate mechanical function with changes in running speed and slope. The muscles studied were the iliotibialis lateralis pars postacetabularis (ILPO), a biarticular knee and hip extensor, and the femorotibiali...

We investigated the mechanical function of two ankle extensor muscles, the lateral gastrocnemius (LG) and peroneus longus (PL), in wild turkeys Meleagris gallopavo during steady speed running. We hypothesized that mechanical work output of the LG and PL during running parallels the demand for mechanical work on the body. The turkeys ran on level, i...

Recent work has provided measurements of power output in avian skeletal muscles during running and flying, but little is known about the contractile properties of avian skeletal muscle. We used an in situ preparation to characterize the force-velocity properties of two hind limb muscles, the lateral gastrocnemius (LG) and peroneus longus (PL), in W...

Comparative musculoskeletal modeling represents a tool to understand better how motor system parameters are fine-tuned for specific behaviors. Frog jumping is a behavior in which the physical properties of the body and musculotendon actuators may have evolved specifically to extend the limits of performance. Little is known about how the joints of...

The caudofemoralis muscle is the largest muscle that inserts onto the hindlimb of most ectothermic tetrapods, and previous studies hypothesize that it causes several movements that characterize the locomotion of vertebrates with a sprawling limb posture. Predicting caudofemoralis function is complicated because the muscle spans multiple joints with...