Franck Yao

Franck Yao
Institut de Recherche en Sciences de la Santé, Bobo Dioulasso, Burkina Faso · Infectivity/Parasitology

PhD

About

15
Publications
2,859
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195
Citations
Introduction
Currently I’m field entomology coordinator on « Target Malaria » project at IRSS, Burkina Faso where we work on genetically modified mosquitoes . Main activities: Mark Release Recapture experiment (MRR), mosquitoes collection by BG traps, Pesticide Spray Catch (PSC), Swarming (SWN), Breeding sites survey.
Additional affiliations
May 2010 - March 2015
Research Institute of Health Sciences
Position
  • PhD Student
May 2010 - March 2015
Research Institute of Health Science (IRSS/Burkina Faso), Sapienza University of Rome
Position
  • PhD Student
May 2010 - March 2015
Research Institue of Health Science (IRSS/Burkina Faso)
Position
  • PhD Student

Publications

Publications (15)
Article
Full-text available
Every year, malaria kills approximately 405,000 people in Sub-Saharan Africa, most of them children under the age of five years. In many countries, progress in malaria control has been threatened by the rapid spread of resistance to antimalarial drugs and insecticides. Novel genetic mosquito control approaches could play an important role in future...
Article
Full-text available
Whether the malaria parasite Plasmodium falciparum can manipulate mosquito host choice in ways that enhance parasite transmission toward humans is unknown. We assessed the influence of P. falciparum on the blood-feeding behaviour of three of its major vectors (Anopheles coluzzii, An. gambiae and An. arabiensis) in Burkina Faso. Host preference assa...
Article
Full-text available
Background: Seasonal malaria chemoprevention (SMC) consists of administration of sulfadoxine-pyrimethamine (SP) + amodiaquine (AQ) at monthly intervals to children during the malaria transmission period. Whether the addition of azithromycin (AZ) to SMC could potentiate the benefit of the intervention was tested through a double-blind, randomized,...
Article
Full-text available
Background Since the late 1990s, malaria control programmes have relied extensively on mass bednet distribution and indoor residual spraying. Both interventions use pesticides and target mosquitoes coming indoors either to feed or to rest. Unfortunately, these intensified vector control campaigns have resulted in mosquito populations with high leve...
Article
Full-text available
Whether the malaria parasite Plasmodium falciparum can manipulate mosquito host choice in ways that enhance parasite transmission toward humans is unknown. We assessed the influence of P. falciparum on the blood-feeding behaviour of three of its major vectors (Anopheles coluzzii, An. gambiae and An. arabiensis) in Burkina Faso. Host preference assa...
Article
Full-text available
Major efforts are currently underway to develop novel, complementary methods to combat mosquito-borne diseases. Mosquito genetic control strategies (GCSs) have become an increasingly important area of research on account of their species-specificity, track record in targeting agricultural insect pests, and their environmentally non-polluting nature...
Chapter
Full-text available
The 20th century has been a century where inequalities among countries, concerning health, have increased. Several factors can explain this pattern, such as immunization and massive antibiotherapy, but nutrition, housing, and hygiene are also key parameters for health improvement. This heterogeneity among countries is well illustrated by malaria, w...
Article
Full-text available
Background The presence of Plasmodium falciparum gametocytes in peripheral blood is essential for human to mosquito parasite transmission. The detection of submicroscopic infections with gametocytes and the estimation of the gametocyte sex ratio are crucial to assess the human host potential ability to infect mosquitoes and transmit malaria parasit...
Article
Full-text available
Targeting the stages of the malaria parasites responsible for transmission from the human host to the mosquito vector is a key pharmacological strategy for malaria control. Research efforts to identify compounds that are active against these stages have significantly increased in recent years. However, at present, only two drugs are available, name...
Article
Full-text available
Human genetic factors play a key role in determining the resistance/ susceptibility to infectious diseases. It is unknown whether genetic makeup may also influence host efficiency to transmit pathogens. With regard to malaria, a major selective force in recent human evolution, protective erythrocyte variants have been describe, but little is known...
Article
Full-text available
Genetic factors are known to have a role in determining susceptibility to infectious diseases, although it is unclear whether they may also influence host efficiency in transmitting pathogens. We examine variants in HBB that have been shown to be protective against malaria and test whether these are associated with the transmission of the parasite...

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Projects (2)