Franck Duteille

Franck Duteille
Centre Hospitalier Universitaire de Nantes | CHU Nantes · Centre des brûlés Drvice d echirurgie plastique reconstructrice et esthétique

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194
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2,059
Citations
Citations since 2016
45 Research Items
1107 Citations
2016201720182019202020212022050100150
2016201720182019202020212022050100150
2016201720182019202020212022050100150
2016201720182019202020212022050100150

Publications

Publications (194)
Article
Full-text available
Background: Immune homeostasis requires fully functional Tregs with a stable phenotype to control autoimmunity. Although IL-34 is a cytokine first described as mainly involved in monocyte cell survival and differentiation, we recently described its expression by CD8+ Tregs in a rat model of transplantation tolerance and by activated FOXP3+ CD4+ an...
Preprint
Full-text available
Immune homeostasis requires fully functional Tregs with a stable phenotype to control autoimmunity. Although IL-34 is a cytokine first described as mainly involved in monocyte cell survival and differentiation, we recently described its expression by CD8+ Tregs in a rat model of transplantation tolerance and by activated FOXP3+ CD4+ and CD8+ Tregs...
Article
Background: The neurocutaneous sural flap is useful to cover defects of the distal quarter of the lower limb. Nevertheless, severe complications occur in 14% of the cases, and venous congestion is reported in 75% of these cases. This congestion can lead to total necrosis of the flap and a failure of the procedure. We describe a new surgical method...
Article
Résumé Objectifs Le syndrome du canal carpien est rare chez l’enfant. Nous avons réalisé une étude rétrospective chez 10 enfants. L’objectif est de montrer qu’il s’agit d’un diagnostic ardu et de rapporter nos résultats après chirurgie. Patients et méthodes Nous avons identifié tous les enfants ayant eu une compression du nerf médian au niveau du...
Article
Background There has over recent years been a constant increase in annual breast reconstruction figures. While reports indicate that burns following breast reconstruction are a rare occurrence there has nevertheless been a relative increase in cases. The key underlying causes of this type of condition remain unknown. Objectives It was therefore ou...
Article
Background: Deep dermal suturing is critical for scar quality outcomes. We evaluated a new fast medical device for dermal suturing, with hypothesis of non-inferiority with regard to clinical scar and cost-effectiveness. Methods: prospective, patient-blind, randomized, multicentre noninferiority study in 26 french hospitals. Patients were randomi...
Article
Loss of tissue substance in children's limbs has the same etiologies and in many cases, the same severity as in adults’ limbs, and the means placed at the disposal of a surgeon are likewise comparable. It may nonetheless prove difficult to strategically position the different treatment methods in a decision-making tree. After all, a child presents...
Article
Introduction Dual Plane allows, according to J.B Tebbetts, to combine the advantages while reducing the drawbacks of the other implantation pockets. We assessed patient satisfaction using the Breast-Q © questionnaire after breast augmentation using the Dual Plane technique. Material and methods Our study involved evaluating data from the Breast-Q...
Article
Negative Pressure Wound Therapy is a device applied to a wound that causes local depression. There are a few series showing the effectiveness of this treatment in Pediatric. The objective of this work is to try to clarify the indications in children. This is a retrospective series of 25 children between 2004 and 2019. The inclusion criteria were al...
Article
Full-text available
A calcium alginate dressing (ALGINATE) and negative pressure wound therapy (NPWT) are frequently used to treat wounds which heal by secondary intention. This trial compared the healing efficacy and safety of these 2 treatments. Methods: This randomized, non-inferiority trial enrolled patients who underwent skin excision (>30 cm2), which was left...
Article
Les brûlures profondes des doigts (3e degré) sont potentiellement graves car elles nécessitent une excision des tissus nécrosés mettant à nu les structures nobles. Beaucoup de lambeaux locaux ont été décrits au niveau de la main et leur utilisation dans ce contexte peut être particulièrement utile. Nous proposons une série de 50 cas. Notre étude re...
Article
Le traitement chirurgical de l’aplasie/hypoplasie congénitale du pouce reste une intervention exigeante sur le plan technique. Elle est généralement bien acceptée dans les aplasies, plus difficilement dans les hypoplasies sévères en raison de la persistance d’un pouce même non fonctionnel. C’est pourtant souvent la seule solution afin de redonner à...
Article
Key Points First description of the relevance of the CAR engineering approach to develop CAR-CD8+ Tregs for clinical trials in transplantation. A2-CAR CD8+ Treg interactions with HLA-A*02+ ECs induce a noncytotoxic fine-tuned and protolerogenic activation of ECs.
Article
Full-text available
Background: Wound repair is one of the most complex biological processes of human life. Allogeneic cell-based engineered skin substitutes provide off-the-shelf temporary wound coverage and act as biologically active dressings, releasing growth factors, cytokines and extracellular matrix components essential for proper wound healing. However, they...
Article
Introduction: Pollicization of the index finger as a treatment for aplasia and severe congenital thumb hypoplasia remains a demanding surgical procedure. In aplasias, it is generally well-accepted, less in hypoplasias. However, it is often the only solution to give back to the child the possibilities of a pollici-digital grip, guaranteeing an exce...
Article
Les brûlures de deuxième degré superficiel sont les plus fréquentes. Malgré leur excellent pronostic amenant à une cicatrisation dans les dix à douze jours, elles peuvent être compliquées à gérer en raison de l’importance de la douleur. Plusieurs protocoles peuvent être proposés dans le cadre d’une prise en charge à domicile. Le premier impose un p...
Article
Due to an increasing number of major weight loss after bariatic surgery, the demand for body-coutouring surgery increase in paralell. Among all the technics which can be realized, brachioplastyis one of them. The goal is to reach a functionnal but an aesthetic improvement too. The literature show that the rate of major complication is very low (or...
Article
Résumé Objectifs Comparer l’efficacité à court terme du méthoxyflurane vs MEOPA sur la douleur aiguë lors de la réfection des pansements en consultation brûlés adultes, puis évaluer le confort du patient et la qualité du pansement effectué. Patients et méthodes Étude monocentrique, prospective d’avril 2018 à janvier 2019. Ont été inclus les homme...
Article
Objective: Bony resection in children presents a unique reconstructive challenge because of future growth potential. To achieve limb salvage and provide the patient with a functional extremity, vascularized free fibula transfer has become the workhorse for bony reconstruction. The authors present their reconstructive experience using vascularized...
Article
Full-text available
Background Although silicone breast implants have been available for over 60 years their safety and efficacy continue to be assessed via long-term clinical and vigilance studies. Complications often associated with breast implant surgery include but are not limited to capsular contracture and rupture. Objective The authors investigate and evaluate...
Article
La réalisation de greffes de peau mince dermo-épidermique est un acte chirurgical fréquent, réalisé dans de nombreuses disciplines chirurgicales et différentes situations cliniques. Le but est d’obtenir une cicatrisation définitive et d’éviter la phase longue et parfois délicate de l’épidermisation progressive par cicatrisation dirigée. Une étude p...
Article
Introduction: Chronic wounds represent a major health challenge with no current standardized surgical treatment. The use of free flaps is little discussed in the literature, with a supposed propensity to failure given unfavorable local conditions and land often debility. We present here the analysis of our monocentric experience of the use of free...
Article
Most hospitals use protocols for surgical antibioprophylaxis (ABP). Despite SFB’s 2009 recommendations promoting ABP in burn patients and stating the molecules to be used, wide variations exist within hospitals and among French hospitals, in cases of skin grafting and use of dermal substitutes. We contacted surgeons in 12 French Burn Centres (BCs)...
Article
Introduction: The objective of the study is to analyse complications associated with surgery for pelvic pressure ulcers in terms of their frequency, nature and rate of surgical revisions. The secondary aims are to analyse the rate of recurrence, length of stay and time to healing, and to determine factors associated with complications and recurren...
Article
Full-text available
Background: Immunodeficient mice are invaluable tools to analyze the long-term effects of potentially immunogenic molecules in the absence of adaptive immune responses. Nevertheless, there are models and experimental situations that would beneficiate of larger immunodeficient recipients. Rats are ideally suited to perform experiments in which larg...
Article
Full-text available
Both CD4+ and CD8+ Tregs play a critical role in the control of immune responses and immune tolerance; however, our understanding of CD8+ Tregs is limited while they are particularly promising for therapeutic application. We report here existence of highly suppressive human CD8+CD45RClow/− Tregs expressing Foxp3 and producing IFNγ, IL-10, IL-34, an...
Article
Full-text available
Background It has been proposed that negative pressure wound therapy (NPWT) applied prophylactically to a closed incision may decrease the incidence of wound complications. Patients undergoing reduction mammaplasty are at risk of wound complications such as delayed healing, infection, and dehiscence, and the bilateral nature of the surgery allows f...
Article
La pathomimie ou trouble factice avec symptômes physiques est une pathologie psychiatrique à retentissement somatique potentiellement grave. Le nomadisme médical, l’absence de conscience du trouble et l’auto-entretien des lésions conduisent à la chronicisation des plaies, parfois sur plusieurs dizaines d’années, mettant en échec les différents prat...
Article
Introduction: Pectus excavatum is the most common congenital chest malformation and is a common reason for consultation in plastic surgery. Our attitude is most often a filling of the depression with a custom-made silicone prosthesis. The objective of this work was to evaluate the interest of computer-aided design (CAD) of implants compared to the...
Article
Introduction: The management of finger deep burns is still problematic for the surgeon. Due to the fineness and the thickness of the subcutaneous tissue, after excision there is an important risk of exposure of the underlying tissue like bone, nerve or tendons. Local flaps (random pattern flap and pedicle flap) allowed ensuring a good quality cove...
Article
We report the clinical case of a 72-year-old man followed for 10years by a specialized pain center, for neuropathic pain poorly systematized, triggered by the contact of the anteromedial face of the right forearm. After surgical excision, histological analysis indicated a well-circumscribed nodule in the subcutaneous region, confirming that the mas...
Article
Background The safety and efficacy of all medical devices, including breast implants, is important and consistent performance is best shown by undertaking long-term clinical and vigilance studies. Local complications such as capsular contracture and rupture are risks often associated with breast implant surgery. Objectives The authors investigate...
Article
La réalisation d’une greffe de peau mince dermo-épidermique est un acte fréquent, réalisé dans toutes les spécialités chirurgicales. Elle fait appel à une technique validée et reproductible qui laisse peu de place à la discussion. La phase fondamentale qui va souvent conditionner le résultat obtenu reste celle de la préparation du lit receveur de l...
Article
Résumé Les malformations congénitales de la main regroupent un nombre important de situations cliniques. Leur expression est, comme dans toutes les pathologies congénitales, variable. De ce fait, on peut presque considérer que chaque situation clinique est un peu unique. La difficulté, comme toute la pathologie congénitale, réside dans le fait que...
Article
While we celebrated the fortieth anniversary of the first free flap in children, new techniques emerged in reconstructive surgery (NPT, artificial dermis…) and reduced microsurgery procedures. However, microsurgery in children as in adults still have clinical applications in reconstructive surgery. Free flaps remain essential in clinical situations...
Article
Purpose: Conventionally, articles dealing with nasal defects plan reconstructions regarding the aesthetic subunits, imposing their systematic respect. We propose to study the reconstruction of a crossroad region of three subunits, tip, alar lobule and lateral sidewall, where that full compliance is not possible, in our experience of 36 patients....
Article
Full-text available
Langerhans cells (LCs) are epithelial APCs that sense danger signals and in turn trigger specific immune responses. In steady-state, they participate in the maintenance of peripheral tolerance to self-antigens whereas under inflammation LCs efficiently trigger immune responses in secondary lymphoid organs. It has been demonstrated in mice that LC-d...
Article
Background: Autologous adipose tissue transfer may be performed for aesthetic needs following resection of osteosarcoma, the most frequent primary malignant tumor of bone, excluding myeloma. The safety of autologous adipose tissue transfer regarding the potential risk of cancer recurrence must be addressed. Methods: Adipose tissue injection was...
Article
Introduction: In our team, free flap and especially serratus anterior muscle is the first option for the coverage of lower limb post-traumatic defects. For complex tissue loss, it may be advantageous to harvest the free serratus anterior with rib myo-osseous composite flap. We performed 20 osteomuscular serratus anterior composite flap between 200...
Article
Among all complications that affect patients with neurofibromatosis, type I (NF1) are very aggressive malignant nerve sheath tumors (MPNSTs). Surgery is their first line therapy. We report the case of a non metastatic neurofibrosarcoma of the axillary area in a 22-year-old male with NF1. An interscapulothoracic resection was performed to resect the...
Article
INTRODUCTION The spare-parts concept is well described in traumatology of the hand. Tissues of a scarified ray are used to reconstruct another damaged finger. We will detail an application in pediatric hand through a clinical case. MATERIALS AND METHOD We describe a patient presenting a bilateral complete and non-complex syndactyly of the third we...
Article
Congenital hemangiomas (CHs) are rare benign vascular tumors that differ from common infantile hemangiomas in that they grow in utero and are fully developed at birth. While ulceration is a common, predominantly benign complication in infantile hemangioma, little is known about the prognosis of ulcerated CH. However, it has been observed that ulcer...
Chapter
As in every medical discipline, resuscitation techniques are regularly progressing, allowing more and more patients to survive. In these departments, acute skin problems are observed, particularly those linked to the use of vasopressive drugs prescribed to maintain a stable patient haemodynamics. Once the acute phase is solved and the patients are...
Article
Surgical treatment of congenital syndactylies is based on the creation of a new commissure - with a commissural flap - and on the management of fingers lateral faces - with mirror zigzag incisions. Lateral skin defects are covered by full-thickness skin graft. Since their discover 30years ago, dermal substitutes applications have been enlarged. We...
Article
Introduction The carpal tunnel syndrome is a common peripheral neuropathy in adults but is rare in children. We report a series of 10 carpal tunnel syndromes in children. Methods We have supported five children, two males and three females, with a bilateral carpal tunnel syndrome. We studied the clinical history (history, symptoms, stage of diseas...
Article
Occlusive dressings for second-degree hand burns in children must prevent infection and promote healing. For good management of analgesia, these treatments often require children to be hospitalized. Our goal was to find an alternative to conventional care protocol that would reduce the number of dressings and therefore the length of hospitalization...
Article
During breast augmentation, surgical drainage remains a source of debate. The objective of the study was to determine the interest of the drainage after pre-pectoral breast implants pre, analyzing the risk of hematoma and capsular contracture. We retrospectively analyzed a cohort of 400 patients who underwent a first aesthetic breast augmentation b...
Article
Study design: Retrospective study reporting characteristics and management of septic arthritis of the hip due to pressure sores in spinal cord-injured patients. Objectives: To describe clinical and biological data of septic arthritis of the hip and its treating management. Setting: The database of the regional SCI referral center, Nantes, Fran...
Article
Lors de la mise en place d’implants mammaires, le drainage de la loge reste source de débat. L’objectif de l’étude était de déterminer l’intérêt du drainage en position pré-pectorale, en analysant le risque d’hématome et d’apparition de coque à distance.
Article
Les pansements occlusifs des brûlures des mains de 2ème degré chez l’enfant doivent prévenir l’infection et favoriser les phénomènes de cicatrisation. Pour être réalisés correctement avec une bonne prise en charge de l’antalgie, ces soins nécessitent souvent que l’enfant soit hospitalisé. Notre objectif était de trouver une alternative au protocole...
Article
Management of scalps defect is a common subject for reconstructive surgery. The use of local flap is better because of the hairy skin. The auricular posterior artery is often described as an accessory blood supply for the scalp. We present an original case of 16×6 cm scalp flap harvested almost in "vascular island" on the right retro-auricular pedi...
Article
Introduction Management of scalps defect is a common subject for reconstructive surgery. The use of local flap is better because of the hairy skin. Objective The auricular posterior artery is often described as an accessory blood supply for the scalp. Method We present an original case of 16 × 6 cm scalp flap harvested almost in “vascular island”...
Article
This series of five case studies focuses on maintaining the integrity of the periwound skin in a variety of post-operative incisions. To prevent skin-stripping and blistering, TIELLE® Lite was used as primary dressing. In each case, TIELLE Lite's non-adherent wound interface and ability to wick fluid from the wound surface was successful in prevent...
Article
During pregnancy, the Haute Autorité de santé (HAS) recommends to realize three ultrasonographic evaluations, notably for the early detection of congenital malformations. Yet, in our experience, ultrasonographic antenatal diagnoses of hand malformations are rare. This is both a retrospective (years 2003–2008) and a prospective study (2009–2012). It...
Article
Full-text available
Background: Multicenter prospective studies assessing the safety and efficacy of silicone gel breast implants are relatively rare. Eurosilicone S.A.S. present their safety and efficacy data herein for the largest European silicone gel breast implant study published to date. Methods: One thousand and ten of Eurosilicone’s textured cohesive Cristall...
Article
The treatment of wounds by negative pressure requires the use of a foam or gauze interface. The study of scientific articles on the subject shows that the quality of the formation of granulation tissue and the pain during dressing removal differ depending on the technique, in favour of the use of the compress. On the other hand, no difference is fo...
Article
The fascia superficialis temporalis (FST) can be used as a pedicled flap. Its span allows covering important head and neck defects. We present our experience with four patients. The FST flap, grafted with thin skin allowed covering: zygomatic defect after resection of Merkel cell carcinoma; the upper part of the right auricle after exeresis due to...
Article
Introduction Le fascia superficialis temporalis (FST) peut être utilisé comme un lambeau pédiculé. Son arc de rotation et sa surface permettent de couvrir de larges pertes de substance de la tête et du cou. Nous présentons notre expérience de quatre cas. Observations Le lambeau de FST, greffé en peau mince, a permis de couvrir : une perte de subst...
Article
The carpal tunnel syndrome is a common peripheral neuropathy in adults but is rare in children. We report a series of 10 carpal tunnel syndromes in children. We have supported five children, two males and three females, with a bilateral carpal tunnel syndrome. We studied the clinical history (history, symptoms, stage of disease), therapeutic manage...
Article
We report the case of a 72-year-old patient sent by his dermatologist in January 2009 for a back burn. His medical history reported one coronarography and two coronaroplasties between September and October 2005. This enabled us to form the diagnosis of chronic radiodermatitis after coronaroplasty from literature data. The occurrence of chronic radi...
Article
Intraneural perineurioma is a rare benign peripheral sheath tumor, which is most prevalent in adolescents and young adults. It is characterized by focal perineural cell proliferation infiltrating the endoneurium leading to the macroscopic aspect of hypertrophic nerve. It typically presents a loss of motor function in the involved nerve. We report t...
Article
We report the case of a 72-year-old patient sent by his dermatologist in January 2009 for a back burn. His medical history reported one coronarography and two coronaroplasties between September and October 2005. This enabled us to form the diagnosis of chronic radiodermatitis after coronaroplasty from literature data. The occurrence of chronic radi...
Article
During pregnancy, the Haute Autorité de santé (HAS) recommends to realize three ultrasonographic evaluations, notably for the early detection of congenital malformations. Yet, in our experience, ultrasonographic antenatal diagnoses of hand malformations are rare. This is both a retrospective (years 2003-2008) and a prospective study (2009-2012). It...
Article
Intraneural perineurioma is a rare benign peripheral sheath tumor, which is most prevalent in adolescents and young adults. It is characterized by focal perineural cell proliferation infiltrating the endoneurium leading to the macroscopic aspect of hypertrophic nerve. It typically presents a loss of motor function in the involved nerve. We report t...
Article
Subject: The foot is a region of the lower limb presenting some functional and aesthetic particularities. Free flap surgery is often indicated in complex traumatic foot defects (bony and soft tissue) of the foot. In this kind of trauma, we prefer to use the serratus anterior-rib free flap. We report four cases with this technique while analyzing t...
Article
Nasal amputation in the child is infrequent, and the procedure is not clearly defined. Early reconstruction certainly improves the child's life and social integration. The major risk is unsatisfactory growth of the reconstructed nose, which may persuade some surgeons to postpone the operation. The evaluation of this nasal reconstruction in a 5-year...
Article
Nylon-reinforced silver sodium carboxymethylcellulose (AQUACEL(®) Ag BURN) dressings were developed to be pliable and conforming for the management of partial-thickness burns. This study evaluated the AQUACEL(®) Ag BURN glove for the management of hand burns. This 21-day, phase II, prospective, non-comparative study included 23 patients with partia...
Article
The authors report the results of a multicenter prospective study evaluating a novel technology: dermal suture using absorbable staples composed of polylactic and polyglycolic acids. From January to June 2009, 59 dermal sutures were performed with Insorb absorbable staples and 41 with absorbable thread. All patients in the study underwent abdominal...
Article
Introduction: There is no single therapeutic scheme for the management of intermediary 2nd-degree facial burns, which can cause problems because of their uncertain course. It is preferable to obtain optimal healing of the face in order to avoid functional or cosmetic sequelae. Some practitioners recommend early excision (first week) of these burns...
Article
Full-text available
Negative Pressure Wound Therapy (NPWT) has become widely adopted over the last 15 years and over 1000 peer-reviewed publications are available describing its use. Despite this, there remains uncertainty regarding several aspects of usage. In order to respond to this gap a global expert panel was convened to develop evidence-based recommendations de...
Article
The use of microsurgery in the management of burn sequelae is not a new idea and free flaps have been used in this context since the 1970s. New technologies like negative pressure treatment and skin substitute have certainly decreased the indication of free flaps. The authors with their experience combined to a review of the literature, try to clar...
Article
The use of microsurgery in the management of burn sequelae is not a new idea and free flaps have been used in this context since the 1970s. New technologies like negative pressure treatment and skin substitute have certainly decreased the indication of free flaps. The authors with their experience combined to a review of the literature, try to clar...
Article
Full-text available
Negative pressure wound therapy (NPWT) is becoming a commonplace treatment in many clinical settings. New devices and dressings are being introduced. Despite widespread adoption, there remains uncertainty regarding several aspects of NPWT use. To respond to these gaps, a global expert panel was convened to develop evidence-based recommendations des...
Article
Burns of the hands are relatively common because of their exposure and the risk of accidents occurring during their use. Among these cases, the management of complex burns in the acute stage continues to present a difficult problem. In this article we first define which clinical situations might correspond to the idea of the “complex hand”, and we...
Article
Cutaneous bronchogenic cysts are very rare congenital lesions. Scapular localization is frequently found in the literature. Only the histological analysis can confirm the diagnosis, because no clinical characteristic is pathognomonic. Surgical excision of the lesion is justified by the risk of local infection and discomfort related to the recurrent...
Article
We report the case of a patient with mammary implants for 42 years. She presented for three years a change of the general state with clinicobiological demonstrations of indefinite origin, and a progressive bilateral increase of her mammary volume until it became exceptional. The surgery of explantation allowed the retreat of two masses of almost 6k...
Article
From 2004 to 2007, 148 limb free flaps were performed in a series of 138 patients at the University Hospital in Nantes, France. Flaps were successful in 127 instances (rate: 86%; group A) and failed in 21 (group B). An analysis of the various factors (pre-, intra-, and postoperative) in both groups that may have influenced the outcome of surgery id...