Francisco J Corpas

Francisco J Corpas
Spanish National Research Council | CSIC · of Stress, Development and Signaling in Plants, Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture

Professor

About

397
Publications
70,478
Reads
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25,410
Citations
Citations since 2017
157 Research Items
13409 Citations
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201720182019202020212022202305001,0001,5002,0002,500
201720182019202020212022202305001,0001,5002,0002,500
Introduction
FJ Corpas research is focused on the metabolism of ROS and RNS under physiology and environmental stress conditions. Special interest is its implications in fruit ripening and in the nitro-oxidative metabolism of plant peroxisomes. Honors and Awards: Highly Cited Researcher (HCR) 2022 in recognition of exceptional research performance demonstrated by production of multiple highly cited papers that rank in the top 1% for field and year in Cross-Field
Additional affiliations
March 2014 - present
Spanish National Research Council (CSIC)
Position
  • Head of Department
September 2007 - February 2014
Estación Experimental del Zaidin, Spanish National Research Council, Granada
Position
  • Responsible Scientist of the Scientific Instrumentation Service
June 2003 - August 2003
Kinki University, 3327-204 Nakamachi, Nara 631-8505, Japan.
Position
  • Researcher

Publications

Publications (397)
Article
Plant peroxisomes have an active nitro-oxidative metabolism. However, the assay of reactive oxygen and nitrogen species (ROS/RNS) could be a challenge since the purification of peroxisomes is technically a high time-consuming approach that needs to be optimized for each tissue/organ (root, leaf, fruit) and plant species. Arabidopsis thaliana, as a...
Article
Aims: Pepper fruit is a horticultural product worldwide consumed which has great nutritional and economic relevance. NO and H2S are recognized signal molecules that can exert regulatory functions. This study aims to analyze the interrelationship between NO and H2S during fruit ripening. Results: Our data indicate that the H2S-generating L-cystei...
Chapter
Nitric oxide (NO) and hydrogen sulfide (H2S) are two recognized signal molecules in higher plants involved in a wide range of physiological processes and the mechanisms of response against adverse environmental conditions. These molecules can interact to provide an adequate response to palliate the negative impact exerted by stressful conditions, p...
Chapter
Hydrogen sulfide (H2S) is a signaling molecule that achieves different regulatory functions in animal and plant cells. The cytosolic enzyme L-cysteine desulfhydrase (LCD; EC 4.4.1.28) catalyzes the conversion of cysteine (L-Cys) to pyruvate and ammonium with the concomitant generation of H2S, this enzyme being considered one of the main sources of...
Article
Salt stress is one of the common environmental threats to crop growth, development, and productivity. Plant growth regulators (PGRs) are natural messengers and are known to play pivotal roles at different stages of the growth and development of plants under various environmental conditions. Keeping in mind the importance of PGRs in stress managemen...
Article
Full-text available
Lemongrass (Cymbopogon flexuosus) has great relevance considering the substantial commercial potential of its essential oil. Nevertheless, the increasing soil salinity poses an imminent threat to lemongrass cultivation given its moderate salt-sensitivity. For this, we used silicon nanoparticles (SiNPs) to stimulate salt tolerance in lemongrass cons...
Article
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Climate change and abiotic stress factors are the key players in crop losses around the globe. Among the different stresses, extreme temperatures (heat and cold) disturb plant growth and development, reduces productivity, and in severe cases, leads to plant death. The plants have developed numerous strategies to safeguard themselves against the det...
Article
Full-text available
Small heat shock proteins (sHSPs) are usually upregulated in plants under diverse environmental stresses. These proteins have been suggested to function as molecular chaperones to safeguard other proteins from stress-induced damage. The ripening of pepper (Capsicum annuum L.) fruit involves important phenotypic, physiological, and biochemical chang...
Article
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Fruits are unique to flowering plants and confer a selective advantage to these species by facilitating seed maturation and dispersal [...]
Article
Hydrogen peroxide (H2 O2 ) is a reactive oxygen species (ROS) and a key modulator of the development and architecture of the root system under physiological and adverse environmental conditions. Nitric oxide (NO) and hydrogen sulfide (H2 S) also exert myriad functions on plant development and signaling. Accumulating pieces of evidence show that dep...
Article
Full-text available
Lipoxygenases (LOXs) catalyze the insertion of molecular oxygen into polyunsaturated fatty acids (PUFA) such as linoleic and linolenic acids, being the first step in the biosynthesis of a large group of biologically active fatty acid (FA)-derived metabolites collectively named oxylipins. LOXs are involved in multiple functions such as the biosynthe...
Article
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Potassium (K⁺) plays a crucial role in plant homeostasis, and its deficiency significantly impacts photosynthesis, triggering a decrease in growth and crop production. K⁺ starvation induced a significant reduction in the net photosynthetic rate, and the drop is associated with resistance of CO2 diffusion through stomatal conductance, mesophyll cond...
Article
Along with the rapidly increasing environmental contamination by heavy metals, the exposure of plants to chromium has also magnified, resulting in a declined productivity. Hexavalent chromium [Cr(VI)], the most toxic form of Cr, brings about changes in plant processes at morpho-physiological and biochemical levels. However, silicon (Si) is known to...
Article
The phytohormone auxin acts as an important signaling molecule having regulatory functions during the growth and development of plants. Reactive oxygen species (ROS) are also known to perform signaling functions at low concentrations, however, over-accumulation of ROS due to various environmental stresses damages the biomolecules, cell structures a...
Chapter
The ripening of fleshy fruit is a complex physiological process that involves drastic changes at phenotypic, genomic, proteomic, and biochemical levels, where the different subcellular compartments undergo biochemical and metabolic reorganizations, the shift of chloroplasts to chromoplasts being perhaps the best example. In this process, the unripe...
Article
Full-text available
Salt stress severely limits the productivity of crop plants worldwide and its detrimental effects are aggravated by climate change. Due to a significant world population growth, agriculture has expanded to marginal and salinized regions, which usually render low crop yield. In this context, finding methods and strategies to improve plant tolerance...
Article
Full-text available
H2O2 is an essential component of reactive oxygen species (ROS) metabolism and an obligatory side-product of aerobic respiration among plant cells. It is needed for plant growth, development, and stress management along with signalling properties. H2O2 is intricately involved in the stomatal closure during drought stress in conjunction with abscisi...
Article
Full-text available
Various stress conditions, such as drought, salt, heavy metals, and extreme temperatures, have severe deleterious effects on plant growth and directly lead to a decline in yield and quality [...]
Article
Wang et al. recently showed that, in soybean (Glycine max), root nodule formation is induced by a light-triggered signal that moves from the upper part of the plant to the roots. This novel signaling process opens a new area of research aimed to optimize the carbon–nitrogen balance in plant–rhizobium symbiosis.
Article
Full-text available
H2S has acquired great attention in plant research because it has signaling functions under physiological and stress conditions. However, the direct detection of endogenous H2S and its potential emission is still a challenge in higher plants. In order to achieve a comparative analysis of the content of H2S among different plants with agronomical an...
Article
Full-text available
Peroxisomes are ubiquitous organelles from eukaryotic cells characterized by an active nitro-oxidative metabolism. They have a relevant metabolic plasticity depending on the organism, tissue, developmental stage, or physiological/stress/environmental conditions. Our knowledge of peroxisomal metabolism from fruits is very limited but its proteome is...
Article
Nitric oxide (NO) is an endogenous free radical involved in the regulation of a wide array of physio-biochemical phenomena in plants. The biological activity of NO directly depend on its cellular concentration which usually changes under stress conditions, it participates in maintaining cellular redox equilibrium and regulating target checkpoints w...
Article
The physiological process of fruit ripening is associated with the late developmental stages of plants in which mitochondrial organelles play an important role in the final success of this whole process. Thus, an isobaric tag for relative and absolute quantification (iTRAQ)-based analysis was used to quantify the mitochondrial proteome in pepper fr...
Article
Full-text available
Nitric oxide (NO) is a free radical which modulates protein function and gene expression throughout all stages of plant development. Fruit ripening involves a complex scenario where drastic phenotypical and metabolic changes take place. Pepper fruits are one of the most consumed horticultural products worldwide which, at ripening, undergo crucial p...
Article
Full-text available
Fruit ripening is a physiological process that involves a complex network of signaling molecules that act as switches to activate or deactivate certain metabolic pathways at different levels, not only regulating the gene and protein expression but also through post-translational modifications (PTMs) of the involved proteins. Ethylene is the distinc...
Article
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The thiol group of cysteine (Cys) residues, often present in the active center of the protein, are of particular importance to protein function which is significantly determined by the redox state of a protein’s environment. Our knowledge of different thiol-based oxidative post-translational modifications (oxiPTMs), which compete for specific prote...
Article
Nitric oxide (NO) is a multifunctional gaseous signal that modulates the growth, development and stress tolerance of higher plants. NO donors have been used to boost plant endogenous NO levels and to activate NO‐related responses, but this strategy is often hindered by the relative instability of donors. Alternatively, nanoscience offers a new, pro...
Article
Full-text available
Potassium (K+) is an essential macro-element for plant growth and development given its implication in major processes such as photosynthesis, osmoregulation, protein synthesis, and enzyme function. Using 30-day-old Cakile maritima plants as halophyte model grown under K+ deprivation for 15 days, it was analyzed at the biochemical level to determin...
Article
Full-text available
Reactive oxygen species (ROS) of varied types can be yielded in plants at several primary sites (such as the chloroplast, mitochondria, and peroxisomes) under normal aerobic metabolism via processes including photosynthetic and respiratory electron transport chains. However, impaired oxidant-antioxidant balance and extreme growth conditions in plan...
Article
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Chitosan is a poly-(d)-glucosamine that has multiple biomedical, horticultural, or agricultural applications. However , the modifications of its physicochemical properties such as size, density, or surface area by controlled irradiation have started to be explored by biotechnological companies as it seems to improve its beneficial properties and ex...
Article
Melatonin, a tryptophan-derived molecule, is endogenously generated in animal, plant, fungal and prokaryotic cells. Given its antioxidant properties, is involved in a myriad of signalling functions associated with various aspects of plant growth and development. In higher plants, melatonin interacts with plant regulators such as phytohormones, as w...
Article
As a result of climate change, abiotic stresses are the most common cause of crop losses worldwide. Abiotic stresses significantly impair plants' physiological, biochemical, molecular and cellular mechanisms, limiting crop productivity under adverse climate conditions. However, plants can implement essential mechanisms against abiotic stressors to...
Article
Nitric oxide (NO), a signaling free radical, is directly or indirectly involved in virtually all plant physiological processes. Although the enzymatic NO source L-arginine (L-Arg)-dependent nitric oxide synthase (NOS) has been well characterized in animal systems, how NO is enzymatically generated in higher plants remains a subject of debate.
Article
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Nanotechnology is a research area that has experienced tremendous development given the enormous potential of nanoparticles (NPs) to influence almost all industries and conventional processes. NPs have been extensively used in agriculture to improve plant physiology, production, and nutritional values of plant-based products. The large surface area...
Article
Reactive oxygen species (ROS) are involved in plant development and stress acclimation. Recently, Li et al. reported that ROS production is controlled by receptor-like cytoplasmic kinase (RLCK)-mediated respiratory burst oxidase homolog D (RBOHD) phosphorylation, which subsequently regulates pathogen-associated molecular pattern (PAMP)-triggered im...
Article
Full-text available
Excess selenium (Se) causes toxicity, and nitric oxide (NO)’s function in spermine (Spm)-induced tolerance to Se stress is unknown. Using wheat plants exposed to 1 mM sodium selenate—alone or in combination with either 1 mM Spm, 0.1 mM NO donor sodium nitroprusside (SNP) or 0.1 mM NO scavenger cPTIO—the potential beneficial effects of these compoun...
Article
Full-text available
Excess selenium (Se) causes toxicity, and nitric oxide (NO)’s function in spermine (Spm)-induced tolerance to Se stress is unknown. Using wheat plants exposed to 1 mM sodium selenate—alone or in combination with either 1 mM Spm, 0.1 mM NO donor sodium nitroprusside (SNP) or 0.1 mM NO scavenger cPTIO—the potential beneficial effects of these compoun...
Article
When applied exogenously, silica (Si) can have a beneficial impact on plants under biotic stress conditions, as revealed by its recent application in the form of nanoparticles (SiO2NPs) to induce pathogen resistance (El-Shetehy et al.). This opens up a new window of research into combating the devastating effects of biotic stresses.
Article
Full-text available
Protein persulfidation is a post-translational modification (PTM) mediated by hydrogen sulfide (H2S), which affects the thiol group of cysteine residues from target proteins and can have a positive, negative or zero impact on protein function. Due to advances in proteomic techniques, the number of potential protein targets identified in higher plan...
Article
Full-text available
Arsenic (As) negatively affects plant development. Using rice as a model, this study evaluates how the application of silicon (10 µM Si) can favour the formation of adventitious roots under arsenate stress (50 µM As V) as a mechanism to mitigate its negative effects. Indeed, the simultaneous application of As V and Si up-regulated the expression of...
Book
This volume not only focusses the role of hydrogen sulfide in the acclimation of plants but also gives a brief description on the biosynthesis of hydrogen sulfide Mechanism of action of hydrogen sulfide during stress signaling Interaction of hydrogen sulfide with other signaling molecules Physiological, biochemical, and molecular aspects of hydroge...
Chapter
Tryptophan (Trp) is an aromatic amino acid which is synthesized through the shikimate/chorismate pathway. Behind that this amino acid is part of proteins; the relevance of Trp resides as a precursor of secondary metabolism which includes relevant molecules such as auxin (indole-3-acetic acid, IAA), serotonin and melatonin which have a wide range of...
Chapter
Fruit ripening is a complex physiological process involving many external modifications affecting shape, color, flavor, and metabolite composition, among others, which are consequence of deeper changes at biochemical, molecular, and cellular level. Hydrogen sulfide (H2S) is a gasotransmitter molecule that is endogenously produced in plant cells by...
Article
Nitric oxide (NO) and hydrogen sulfide (H2S) are gasotransmitters, which are involved in almost all plant physiological and stress-related processes. With its antioxidant regulatory properties, NO on its own ameliorates plant stress, while H2S, a foul-smelling gas, has differential effects. Recent studies have shown that these signaling molecules a...
Article
Nitric oxide (•NO) is a free radical which exerts a myriad of functions in the physiology of higher plants either under physiological and environmental stress conditions. NO, and derived molecules designated as reactive nitrogen species (RNS), can mediate posttranslational modifications (PTMs) of proteins which can affect their functionality. Among...
Article
Full-text available
Nitric oxide (NO) and hydrogen sulfide (H2S) are two molecules that share signaling properties in plant and animal cells. NO and H2S originate two families of derived molecules designated reactive nitrogen and sulfur species (RNS and RSS, respectively). These molecules are responsible for certain protein regulatory processes through posttranslation...
Article
Full-text available
Pepper (Capsicum annuum L.) fruits are one of the most consumed vegetables worldwide. This produce has a great agro-economical relevance, since it is extensively cultivated. These fruits are characterized by their high content of vitamins C and A [1]. Capsicum annuum has many varieties, whose fruits differ in size, shape, color, and pungency, this...
Conference Paper
Full-text available
Pepper (Capsicum annuum L.) fruits are one of the most consumed vegetables worldwide. Ripening of pepper fruits has been well characterized both phenologically and metabolically. Recently , nitric oxide (NO) has been proved to delay pepper fruit ripening and to enhance the ascor-bate concentration about 40%. Recent research carried out in our labor...
Article
Full-text available
Heat stress adversely affects plants growth potential. Global warming is reported to increase in the intensity, frequency, and duration of heatwaves, eventually affecting ecology, agriculture and economy. With an expected increase in average temperature by 2–3 °C over the next 30–50 years, crop production is facing a severe threat to sub-optimum gr...
Article
Full-text available
Plant species are precursors of a wide variety of secondary metabolites that, besides being useful for themselves, can also be used by humans for their consumption and economic benefit. Pepper (Capsicum annuum L.) fruit is not only a common food and spice source, it also stands out for containing high amounts of antioxidants (such as vitamins C and...
Article
Full-text available
Exogenous applications of silicon (Si) can initiate cellular defence pathways to enhance plant resistance to abiotic and biotic stresses. Plant Si accumulation is regulated by several transporters of silicic acid (e.g. Lsi1, Lsi2, and Lsi6), but the precise mechanisms involved in overall Si transport and its beneficial effects remains unclear. In s...
Preprint
Plant species are precursors of a wide variety of secondary metabolites that, besides having useful activity for themselves, can also be used by humans for their consumption and economic benefit. Pepper (Capsicum annuum L.) fruit is not only a common food and spice source, but it also stands out for containing high amounts of antioxidants (such as...
Article
Full-text available
The peroxisome is a single-membrane subcellular compartment present in almost all eukaryotic cells from simple protists and fungi to complex organisms such as higher plants and animals. Historically, the name of the peroxisome came from a subcellular structure that contained high levels of hydrogen peroxide (H2O2) and the antioxidant enzyme catalas...
Article
The free radical nitric oxide (NO) and the phenolic phytohormone salicylic acid (SA) are signal molecules which exert key functions at biochemical and physiological levels. Abiotic stresses, especially in early plant development, impose the biggest threats to the agricultural system and yield of crops. These stresses impair plant growth and subsequ...
Article
Lemongrass (Cymbopogon flexuosus (Steud.) Wats) is an aromatic grass with great industrial potential. It is cultivated for its essential oil (EO) which has great economical value due to its numerous medicinal, cosmetic and culinary applications. The present study was conducted on silicon nanoparticles (SiNPs) application to lemongrass with the obje...
Article
Potassium (K⁺) exerts key physiological functions such as osmoregulation, stomatal movement, membrane transport, protein synthesis and photosynthesis among others. Previously, it was demonstrated in Arabidopsis thaliana that the loss of function of the chloroplast K⁺ Efflux Antiporters KEA1 and KEA2, located in the inner envelope membrane, provokes...
Article
Nanoparticle-pollution has associated severe negative effects on crop productivity. Hence, methods are needed to alleviate nano-toxicity in crop plants. The present study aims to evaluate if the exogenous hydrogen sulfide (H2S) application in combination with silicon (Si) could palliate the harmful effects of copper oxide nanoparticles (CuO NPs). F...
Book
This book provides an overview of the recent advancements for plant scientists with a research focus on phytohormones and their responses (nature, occurrence, and functions) in plant cells. This book focuses on the role of phytohormones in biosynthesis, plant sexual reproduction, seed germination and fruit development and ripening. It further highl...
Article
Full-text available
The involvement of nitric oxide (NO) and hydrogen sulfide (H2S) in countermanding heat-inhibited photosynthetic features were studied in wheat (Triticum aestivum L.). Heat stress (HS) was employed at 40 °C after establishment for 6 h daily, and then plants were allowed to recover at 25 °C and grown for 30 days. Glucose (Glc) content increased under...
Article
Nitric oxide (NO) is a short-life and free radical molecule involved in a wide range of cellular, physiological and stressful processes in higher plants. In recent years it has been observed that exogenous NO application can palliate adverse damages against abiotic and biotic stresses. Conversely, there is accumulating information indicating that e...
Article
Nitric oxide (NO) has been increasingly implicated as part of the ripening regulatory networks in fleshy fruits. However, very little is known about the simultaneous action of NO on the intertwined web of regulatory events and metabolic reactions behind the ripening-related changes in fruit color, taste, aroma and nutritional value. Here, we perfor...
Article
The present study aims to analyse the potential crosstalk between nitric oxide (NO) and hydrogen sulfide (H2S) in triggering resilience of maize (Zea mays L.) seedlings to hexavalent chromium (Cr VI). Exogenous application of 500 μM sodium nitroprusside (SNP, as a NO donor) or sodium hydrosulfide (NaHS, as a H2S donor) to 9-day-old maize seedlings,...
Article
Arsenic (As) is a toxic metalloid that adversely affects plant growth, and poses severe risks to human health. It induces disturbance to many physiological and metabolic pathways such as nutrient, water and redox imbalance, abnormal photosynthesis and ATP synthesis and loss of membrane integrity. Nitric oxide (NO) is a free radical molecule endogen...
Article
Metalloids are among the major pollutants posing a risk to the environment and global food security. Plant roots uptake these toxic metalloids from the soil along with other essential minerals. Plants respond to metalloid stress by regulating the distribution and levels of various endogenous phytohormones. Recent research showed that auxin is instr...
Article
Nitric oxide (NO) and hydrogen sulfide (H2S) are two key molecules in plant cells which participate, directly or indirectly, as regulators of protein functions through derived posttranslational modifications (PTMs) mainly tyrosine nitration, S-nitrosation and persulfidation. These PTMs allow the participation of both NO and H2S signal molecules in...
Article
Full-text available
Capsicum is the genus where a number of species and varieties have pungent features due to the exclusive content of capsaicinoids such as capsaicin and dihydrocapsaicin. In this work, the main enzymatic and non-enzymatic systems in pepper fruits from four varieties with different pungent capacity have been investigated at two ripening stages. Thus,...
Article
Background During their post-harvest life, horticultural crops are affected by a diverse range of processes, such as natural in planta senescence and fungal infection, as well as artificial conservation techniques, leading to a deterioration in nutritional quality due to chilling damage. Given its intracellular reducing power, the supply of NADPH n...
Article
Hydrogen sulfide (H2S) has become a new signal molecule in higher plants which seems to be involved in almost all physiological processes from seed germination, root and plant growth until flowering and fruit ripening. Moreover, H2S also participates in the mechanism of response against adverse environmental stresses. However, its basic biochemistr...