Francesco Maroso

Francesco Maroso
University of Ferrara | UNIFE · Department of Life Sciences and Biotechnologies

About

49
Publications
6,177
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
236
Citations
Introduction
I am fascinated by the huge amount of information hidden in the genome, and I am curious to look into it to find the footprints of evolution and adaptation. This information is used for the development of tools for the conservation of the biodiversity and the development of a sustainable primary production. I currently work at the Department of Life Science and Biotechnologies at the University of Ferrara, in the group led by prof. G. Bertorelle.

Publications

Publications (49)
Article
Full-text available
Abstract Knowledge on correlations between environmental factors and genome divergence between populations of marine species is crucial for sustainable management of fisheries and wild populations. The edible cockle (Cerastoderma edule) is a marine bivalve distributed along the Northeast Atlantic coast of Europe and is an important resource from bo...
Article
Full-text available
The identification of the genetic basis of domestication in fish species is of timely importance for the aquaculture industry in order to increase productivity, quality, and the welfare of farmed fish. The goal of this study is to investigate the largely unknown aquaculture-induced evolution in gilthead seabream, which is one of the most important...
Article
Full-text available
Background Understanding sex determination (SD) across taxa is a major challenge for evolutionary biology. The new genomic tools are paving the way to identify genomic features underlying SD in fish, a group frequently showing limited sex chromosome differentiation and high SD evolutionary turnover. Turbot (Scophthalmus maximus) is a commercially i...
Article
Full-text available
Background The irruption of Next-generation sequencing (NGS) and restriction site-associated DNA sequencing (RAD-seq) in the last decade has led to the identification of thousands of molecular markers and their genotyping for refined genomic screening. This approach has been especially useful for non-model organisms with limited genomic resources....
Article
The maintenance of biological diversity at ecosystem, species and intraspecific levels is essential to ensure the survival of forests. The palaeartic yew Taxus baccata is part of a number of threatened forest types with prioritized conservation value in Europe. We investigated the spatial distribution of microsatellite genetic diversity in forty-si...
Article
Full-text available
Gilthead sea bream is an important target for both recreational and commercial fishing in Europe, where it is also one of the most important cultured fish. Its distribution ranges from the Mediterranean to the African and European coasts of the North-East Atlantic. Until now, the population genetic structure of this species in the wild has largely...
Preprint
Full-text available
Knowledge on how environmental factors shape the genome of marine species is crucial for sustainable management of fisheries and wild populations. The edible cockle (Cerastoderma edule) is a marine bivalve distributed along the Northeast Atlantic coast of Europe and is an important resource from both commercial and ecological perspectives. We perfo...
Preprint
Full-text available
Background The irruption of Next-generation sequencing (NGS) and restriction site-associated DNA sequencing (RAD-seq) in the last decade has led to the identification of thousands of molecular markers and their genotyping for refined genomic screening. This approach has been especially useful for non-model organisms with limited genomic resources....
Preprint
Full-text available
Background: The irruption of Next-generation sequencing (NGS) and restriction site-associated DNA sequencing (RAD-seq) in the last decade has led to the identification of thousands of molecular markers and their genotyping for refined genomic screening. This approach has been especially useful for non-model organisms with limited genomic resources....
Preprint
Full-text available
Gilthead sea bream is an important target for both recreational and commercial fishing in Europe, where it is also one of the most important cultured fish. Its distribution range goes from the Mediterranean to the African and European coasts of the North-East Atlantic. So far, the genetic structure of this species in the wild has been studied with...
Article
Full-text available
Selective breeding for improving host responses to infectious pathogens is a promising option for disease control. In fact, disease resilience, the ability of a host to survive or cope with infectious challenge, has become a highly desirable breeding goal. However, resilience is a complex trait composed of two different host defence mechanisms, nam...
Article
Developing reliable tools to trace food origin represents a major goal for producers and control authorities. Here, we test the hypothesis whether NGS-generated data could provide a reliable tool to ensure seafood traceability. As a test case, we used the Manila clam Ruditapes philippinarum, a bivalve mollusk of high commercial interest with worldw...
Article
Full-text available
Sexual dimorphism is a fascinating subject in evolutionary biology and mostly results from sex-biased expression of genes, which have been shown to evolve faster in gonochoristic species. We report here genome and sex-specific transcriptome sequencing of Sparus aurata, a sequential hermaphrodite fish. Evolutionary comparative analysis reveals that...
Article
• Application of genomics tools for conservation purposes (i.e. conservation genomics) allows looking deep into the genetic structure and adaptations of populations and species in order to define management units, trace exploited stocks, and identification of species. • In this work, a double‐digestion restriction‐site‐associated DNA sequencing (dd...
Article
Full-text available
Highly dense linkage maps enable positioning thousands of landmarks useful for anchoring the whole genome and for analysing genome properties. Turbot is the most important cultured flatfish worldwide and breeding programs in the fifth generation of selection are targeted to improve growth rate, obtain disease resistant broodstock and understand sex...
Article
Full-text available
Unraveling adaptive genetic variation represents, in addition to the estimate of population demographic parameters, a cornerstone for the management of aquatic natural living resources, which in turn, represent the raw material for breeding programs. The turbot (Scophthalmus maximus) is a marine flatfish of high commercial value living on the Europ...
Article
The development of Genotyping-By-Sequencing (GBS) technologies enables cost-effective analysis of large numbers of Single Nucleotide Polymorphisms (SNPs), especially in "non-model" species. Nevertheless, as such technologies enter a mature phase, biases and errors inherent to GBS are becoming evident. Here, we evaluated the performance of double di...
Article
A combination of a RADseq method (ddRAD) with long read high throughput sequencing (Roche 454) was tuned up in order to identify and validate a set of SNPs useful for gene diversity analysis in two important South American commercial tuna (Thunnus albacares and Scomberomorus brasiliensis). A total of 11 and 21 individuals of T. albacares and S. bra...
Article
The aquaculture industry has increasingly aimed at improving economically important traits like growth, feed efficiency and resistance to infections. Artificial selection represents an important window of opportunity to significantly improve production. However, the pitfall is that selection will reduce genetic diversity and increase inbreeding in...
Article
Dolphinfish is an important fish species for both commercial and sport fishing, but so far limited information is available on genetic variability and pattern of differentiation of dolphinfish populations in the Mediterranean basin. Recently developed techniques allow genome-wide identification of genetic markers for better understanding of populat...
Poster
Over-fishing is one of the most complex and argued issue among the human impacts affecting the marine environment. The development of integrated policies for fish stock conservation and its responsible use are essential. Nowadays, genomics is considered an ultimate tool to define stock boundaries and population structure as it expands the focus on...

Network

Cited By

Projects

Projects (5)
Project
Small, declining populations are prone to extinction due to inbreeding, genetic drift and reduced evolutionary potential (extinction vortex). This phenomenon is particularly threatening for endemic species, which represent a unique, unrepeatable biological heritage. Italy is a biodiversity hotspot hosting 35% of the species included in the European IUCN Red List and is particularly rich of such endangered endemics. Extinction risk can be reduced by developing conservation strategies that prevent genetic erosion; this approach requires a detailed knowledge of genetic variation and its consequences. To this aim, we focus on five iconic Italian endemics that are endangered and require urgent actions according to the IUCN: the Apennine brown bear, Aeolian wall lizard, Apennine yellow-bellied toad, Adriatic sturgeon and Ponza grayling. In each of these species, we explore evolutionary dynamics in two populations of different sizes through advanced population genomic approaches. Whole genome (re)sequencing data is used to estimate their demographic histories, genomic diversity, genomic susceptibility to extinction due to mutation load and eligibility for genetic rescue. The effect of fixed deleterious mutations on cellular functions and individual fitness are analyzed using breeding and in vitro functional studies. Our insights will aid a proper management and conservation of these and other endangered species by informing effective interventions to face the ongoing biodiversity crisis. Furthermore, they expand our knowledge of evolutionary dynamics in small populations and, more broadly, the processes underlying biodiversity and adaptation.
Project
The genetic changes associated with domestication in aquaculture pose an increasing threat to the integrity of native fish gene pools. Consequently, there is a bourgeoning need for the development of molecular tools to assess and monitor the genetic impact of escaped or released farmed fish. In addition, exploration of basic links between genetic differences among farmed and wild fish and differences in important life-history traits with fitness consequences are crucial prerequisites for designing biologically informed management strategies. The project ?AquaTrace? will establish an overview of current knowledge on aquaculture breeding, genomic resources and previous research projects for the marine species seabass, seabream and turbot. The project will apply cutting-edge genomic methods for the development of high-powered, cost-efficient, forensically validated and transferable DNA based tools for identifying and tracing the impact of farmed fish in the wild. Controlled experiments with wild and farmed fish and their hybrids will be conducted with salmon and brown trout as model organisms using advanced ?common garden? facilities. These experiments will elucidate the fundamental consequences of introgression by pinpointing and assessing the effects on fitness of specific genomic regions. Generated insights will form the basis of a risk assessment and management recommendations including suggestions for mitigation and associated costs. This information and the developed molecular tools will be available as open-access support to project participants and external stakeholders including the aquaculture industry. The project is expected to facilitate technology transfer to the aquaculture sector by promoting better tailored breeding practices and traceability throughout production chain.