Francesco Dispenza

Francesco Dispenza
Azienda Ospedaliera Universitaria Policlinico "P. Giaccone" Palermo · U.O. Otorinolaringoiatria

MD PhD

About

99
Publications
9,722
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1,103
Citations
Additional affiliations
March 2011 - May 2016
San Giovanni Di Dio Hospital, Agrigento, Italy
Position
  • Medical Doctor
January 2004 - December 2011
Università degli Studi di Palermo
Position
  • Researcher

Publications

Publications (99)
Article
Full-text available
Labyrinthine fistula is a complication of ear cholesteatoma that increase the risk of sensorineural hearing loss. The management of the fistula must be done contextually with mastoidectomy by: leaving cholesteatoma matrix over the fistula, or remove the matrix reconstructing the defect. Objective: analysis of the two techniques to treat labyrinthin...
Article
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Objective: Assessment of value of fat plug myringoplasty as office-based procedure in small tympanic membrane perforations. Material and Methods: Prospective study of consecutive patients undergoing fat plug myringoplasty under local anesthesia. Minimum follow-up considered was 6 months, which included several microscopic examinations. All data wer...
Article
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This prospective study was designed to evaluate the differences between immediate and delayed canal re-entry of otoliths after therapeutic manoeuvres in patients with benign paroxysmal positional vertigo (BPPV). A total of 196 patients with BPPV were visited and 127 matched our inclusion criteria. The mean age was 54.74 years. The horizontal semici...
Article
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Giovanni Filippo Ingrassia revisited and redefined some of Galeno's reports, and was recognized as one of the leading Italian Physicians of the 16(th) century. Ingrassia principally studied the skull, and gave very important contributions to otorhinolaryngology, including the discovery of the stapes. He also isolated the inferior nasal concha from...
Article
The prevalence of benign paroxysmal positional vertigo (BPPV) is becoming more frequent in elderly population. The presence of comorbid factors has to be considered before assessment as well as before commencing any repositioning treatment. Our aims were evaluation of the maneuvers efficacy and evaluation of the applicability of hybrid maneuver (HM...
Article
Background The relationship between nasal functions and middle ear surgery is still under debate. Nasal obstruction is considered as a negative prognostic factor in middle ear surgery. This is based on the theory that it may cause Eustachian tube dysfunction (ETD) by leading to reduced ventilation of the middle ear, as found in several patients wit...
Article
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Objective: Tumours of the nasal septum are a rare and heterogeneous group of lesions in the sinonasal tract. The management of the different lesions of this site is debated. The aim of this study is to share our experience on a rare clinical condition and stimulate other centres to publish theirs. Methods: We retrospectively analysed the databas...
Article
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Introduction Tympanic retraction is a condition characterized by the displacement of the tympanic membrane toward the structures of the middle ear. Clinically, tympanic retractions can lead to hearing loss, ear discharge and/or ear pain. In most of the cases, however, tympanic retractions are asymptomatic and are found accidentally during an ear, n...
Article
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Purposes Reporting our experience in treating chronic obstructive sialadenitis with a protocol consisting of sialoendoscopy and intraductal instillation of antibiotics, steroids and n -acetyl-cysteine (NAC) solution. Methods Prospective study of patients with chronic obstructive sialadenitis with no apparent lithiasic obstructions, with recurrent...
Article
Background and purpose: The aim of this study was to describe the variations in the speech range profile (SRP) of patients affected by cognitive decline. Methods: We collected the data of patients managed for suspected voice and speech disorders, and suspected cognitive impairment. Patients underwent an Ear Nose and Throat evaluation and Mini-Me...
Chapter
Benign paroxymal positional vertigo (BPPV) is the most common cause of peripheral vertigo and its lifetime incidence in general population is estimated around 10%. Such disease is due to dislodged otoconia that move from utricle into semicircular canals (SCC). Changes of the head position with relation to gravitational vector, make otoconia movemen...
Article
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Vertigo is not itself a disease, but rather a symptom of various syndromes and disorders that jeopardize balance function, which is essential for daily activities. It is an abnormal sensation of motion that usually occurs in the absence of motion, or when a motion is sensed inaccurately. Due to the complexity of the etiopathogenesis of vertigo, man...
Article
Introduction: Migraine vertigo (MV) and Ménière's disease (MD) share several signs and symptoms such as tinnitus, fullness, photophobia, phonophobia, headache and vertigo spells lasting hours. Objective: The aim of the present study was to prospectively observe patients with MV with a sporadic audiological symptom evaluated with clinical examina...
Article
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Purpose This study aims to understand the factors contributing to the severity of oropharyngeal dysphagia and its persistence in the sub-acute phase of stroke. Methods We retrospectively collected the data of all the patients suffering from a stroke in the last year. The severity of stroke was reported according to the NIHSS score. All the patient...
Article
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(1) Background: Inferior turbinates’ hypertrophy is often associated with Eustachian tube dysfunction (ETD); radiofrequency turbinate reduction (RTR) may provide a long-term improvement of nasal obstruction and ETD-related symptoms. (2) Aim: The study aimed to compare ETD in atopic and non-atopic patients before and after RTR and to investigate the...
Article
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Objectives: To evaluate electrophysiological findings among patients with vestibular migraine (VM) and to compare them with those of patients suffering from definite Ménière disease (MD) without migraine. Materials and methods: Twenty-one consecutive patients suffering from VM were enrolled; all subjects were selected according to the criteria p...
Article
Purpose To evaluate the prevalence of oropharyngeal dysphagia in elderly patients suffering from minimal or mild cognitive decline. Patients and methods We retrospectively collected the data of patients suffering from mild cognitive impairment or mild dementia and were undergoing management for suspected oropharyngeal dysphagia, in our department....
Article
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Introduction Retraction pocket is a condition in which the eardrum lies deeper within the middle ear. Its management has no consensus in literature. Objective To assess the role of mastoidectomy in the management of retraction pockets added to a tympanoplasty. Methods Prospective study of patients with retraction pocket and referred to surgery. The...
Article
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Plain-language-summary After successful treatment for benign paroxysmal positional vertigo, many patients may complain of residual dizziness. Possible explanations may be the persistence of otolith into canal insufficient to provoke noticeable nystagmus, utricular dysfunction and undiagnosed coexisting vestibular disorder. We conducted a prospectiv...
Article
Objective: To investigate the role of the period of emergence of the first words and its interactions with other risk factors in predicting the development of speech sound disorder (SSD) among 4- to 5-year-old children. Methods: After 373 children underwent otolaryngology and speech pathology examinations, their parents answered a questionnaire...
Chapter
Neuroplasticity is the ability of central nervous system to modify his own functions based on changes of external or internal factors, and it's the basis for numerous physiologic and pathologic events in otology. Sensorineural hearing loss implies a cochlear deficit but also modifications from acoustic tract up to auditory cortex. It determines mor...
Chapter
Otosclerosis is characterized by a continuous and aberrant process of osteolysis and osteogenesis of the endochondral bone of the otic capsule, most commonly involving the fissula ante fenestram (fenestral otosclerosis) and resulting in a conductive hearing loss. As it undergoes a maturation process, the sclerotic bone may invade deeper into the la...
Article
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BACKGROUND: Down Syndrome (DS) is one of the most frequent genetic abnormalities and the related otolaryngologic disorders may affect a full potential development and the quality of life of these patients. The aim of the present study was to evaluate which treatment, medical or surgical, may improve otolaryngologic symptoms. METHODS: We conducted a...
Article
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Introduction The recurrence rate after tympanoplasty is variable between 0% and 50%. The causes of failure may be different and frequently interrelated, making the surgical choice difficult and the prognosis not always favourable. In this study, we analysed recurrence rate and the possible causes of failure of tympanoplasty in the treatment of tymp...
Article
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Objective:. To examine the difference between outcomes in the administration of concurrent endoscopic sinus surgery (ESS), septoplasty (SP), and rhinoplasty (RP) and concurrent ESS and SP in 1 single surgical session. Methods:. Patients who underwent concurrent ESS and SP from September 2004 to July 2015 were identified. Furthermore, patients among...
Article
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To evaluate whether EBV-DNA can be used as a diagnostic and follow-up parameter for nasopharyngeal tumors in a non-endemic population. The study was carried out in a university hospital. A retrospective study was conducted on 40 paraffin samples of histological preparations. EB-DNA was detected by real-time PCR technique. A prospective study was al...
Article
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Introduction Obstructive sleep apnea syndrome (OSAS) is a sleep disorder caused by an excessive narrowing of the pharyngeal airway that also collapses during inspiration, with an important role played by the lateral pharyngeal wall in the development of the obstruction. Objective To describe our surgical experience with modified expansion sphincter...
Article
Pleomorphic adenoma is the most common benign tumor of the salivary glands. It arises mainly from the parotid, less frequently from the minor salivary glands of the oral cavity and, exceptionally, from the accessory glands widespread in the upper aero-digestive tract. Intranasal localization is rare and mainly affects the glands sited in the nasal...
Article
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Currently, surgical training of physicians in Italy has limited possibilities.Surgical training can be performed on dissection of human bodies as well as in animal laboratories, but experience is very poor. We conducted a survey through an anonymous questionnaire in order to evaluate the opinions of post-graduate physicians on their need for experi...
Book
Vertigo is the feeling that everything around is moving or spinning and is usually caused by a problem with the balance mechanisms in the inner ear. It can also be caused by problems in certain parts of the brain or vision disorders. Benign paroxysmal positional vertigo (BPPV) is one of the most common causes of vertigo causing brief episodes of mi...
Chapter
Newborn babies who need intensive medical care are often sheltered into a special area of the hospital called Neonatal Intensive Care Unit (NICU). In this structure, babies are regularly subject to conditions that would be considered harmful by older children and adults. In the last years, many clinical researches have paid particular attention to...
Chapter
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Sensorineural hearing loss (SNHL) is an inner ear disease which affect from 1 to 3 per 1000 newborns; the World Health Organization estimated a lower prevalence of congenital hearing loss in industrialized countries (2 to 4 per 1000 live births) with respect to developing countries. Particularly, among children admitted to neonatal intensive care u...
Chapter
Leptin is a peptide produced by peptidergic cells or those able to process and secrete peptides. Originally, this function was considered proper and exclusive of certain neurons of the magnocellular and parvicellular hypothalamus. These cells originated from a common precursor, namely neural crest cells, which have the ability to produce hormonal n...
Article
The silent sinus syndrome is an uncommon disease characterized by progressive enophtalmos with diplopia associated with omolateral hypoplasic maxillary sinus without facial and nasal complaints. Atypical presentation with prodromic symptoms as midfacial discomfort could lead the ENT specialist to an early diagnosis with CT scan and prompt surgical...
Article
Aim. Aim of the present study was verifying the static and dynamic anatomic alteration of the upper airways in obese subjects, the correlation between these findings and the sleepdisordered breathing (SDB), verifying the different incidence from android to gynoid obesity in the determination of such disease. Methods. This was a prospective study on...
Article
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Primary objective of this study was to find a statistical link between the most worldwide comorbidities affecting the elderly population (hypertension, diabetes, osteoarthrosis, osteoporosis and depression) and recurrent episodes of BPPV. Secondary objective was defining possible "groups of risk" for people suffering recurrent positional vertigo re...
Article
Inverted papilloma (IP), also known as papilloma Schneideriano or Ewing's papilloma, is the most common benign epithelial tumor of the paranasal sinuses. It originates from the stroma sub-mucosa of the nasal cavity and paranasal sinuses, and as the name suggests, the papillomatous proliferation of squamous epithelium, instead of producing an exophy...
Article
Metatypical Basal Cell Carcinoma, also known as Basosquamous Carcinoma is a subtype of Basal Cell Carcinoma. It is similar to Basal Cell Carcinoma for the gross aspect and regional recurrences, but it has the capacity to spread and develop metastasis. This terrible characteristic endangers the life of the patient if it is not readily recognized by...
Article
To identify the incidence of sensorineural hearing loss (SNHL) on infant at risk and to classify the degree and type of hearing loss describing the main causes associated in Western Sicily. To compare single TEOAE and combined TEOAE/ABR techniques studying the referral rate, the false-positive and false-negative rates through concordance test (κ co...
Chapter
Therapeutic strategies of vestibular schwannomas treatment are changed in the last years. The improvement of surgical equipments and skills allowed increasing the numbers of successful operations in the last 10 years. The results improved in terms of survival, quality of life, recurrences, facial nerve function, and hearing preservation. Also the a...
Article
Children complaints dizziness merit meticulous evaluation to differentially diagnose a vestibular disease. A syndrome mimicking certain classic signs and symptoms of adult vestibular disorders may be presents in children, such as benign paroxysmal positional vertigo, usually associated with aging. Benign paroxysmal vertigo, in which migraine is a m...
Article
Bilateral vocal cord paralysis is a serious illness requiring emergency intervention to resolve the potentially life-threatening respiratory distress. Several surgical procedures were proposed to help improve the airway and to eliminate the tracheostoma in those patients with permanent paralysis. All the procedures have their own advantages and dis...
Article
The aim of the study was to evaluate the true incidence, diagnosis, and treatment of benign paroxysmal positional vertigo (BPPV) arising after whiplash injury and to distinguish this type of posttraumatic vertigo from other types of dizziness complained after trauma. This was a retrospective study comprising patients referred to our center after wh...
Article
The intermediate nerve (IN), also called the nerve of Wrisberg, is a relatively small nerve with a variable anatomical course. Currently, this nerve is not addressed well in the pertinent literature. Pre-operative diagnosis of IN tumours is clinically challenging due to the lack of related symptoms. Symptoms are typically caused by the functional d...
Article
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Primary malignant lymphomas in the salivary glands are relatively rare. Clinical presentation is not characteristic and the disease is often overlooked resulting in diagnosis and treatment delays. To stress the importance of the diagnostic process and combined management, we present a series of eight patients with malignant lymphoma of the parotid...
Article
An insidious percentage of paroxysmal positional vertigo appears to be intractable with canalith repositioning maneuver and also is not self-limiting. This type of positional vertigo is sustained by the action of intracranial tumors that mimics the clinical aspects of benign paroxysmal positional vertigo.Aim of this study is to clarify the features...
Article
The identification of precancerous lesions is the basis of an early diagnosis, and of a treatment that allows, in the great part of cases, the preservation of organ functions. The aims of this study were: the evaluation of the less invasive treatment for precancerous lesion of the larynx to minimize the recurrences, the estimation of number of furt...
Article
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The Facial Nerve Schwannoma is a rare tumor and it seldom involved the middle cranial fossa. Facial nerve schwannoma has various manifestations, including facial palsy but unfortunately facial nerve is very resistant to compression and often facial nerve paralysis or a facial weakness are not present. We present a case of giant facial nerve schwann...
Article
An important component of management of benign paroxysmal positional vertigo (BPPV) has been the application of postural restrictions after use of a canalith repositioning maneuver (CRM) to prevent the return of otolithic debris into the posterior semicircular canal (PSC). This study was designed to explore the effectiveness of postural restriction...
Article
Full-text available
Sudden sensorineural hearing loss is a clinical condition characterized by a sudden onset of unilateral or bilateral hearing loss. In recent years sudden deafness has been frequently described in association with anterior inferior cerebellar artery (AICA) infarction generally presenting along with other brainstem and cerebellar signs such as ataxia...
Article
The aim of this study was to verify the efficacy and the safety of transtympanic dexamethasone to treat sudden sensorineural hearing loss as first and single drug method. Considering ethical implication of performing a mininvasive procedure on middle ear, we matched such proposed treatment with systemic prednisone administration that represents the...
Article
Head and neck involvement in Kaposi's Sarcoma (KS) is not unusual. However, laryngeal involvement is a relatively infrequent manifestation and ENT specialists should consider it in differential diagnosis in laryngeal lesions of AIDS patients and/or subjects from the Mediterranean area. Case report and review of the literature in English. Male patie...
Article
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SUMMARYAim of the present study was to evaluate the effects of obstructive sleep apnoea syndrome (OSAS) on the peripheral and central vestibular system, by means of a case series prospective study at the University referral centre of Otolaryngology Head and Neck Surgery; 45 consecutive patients suffering from OSAS were compared with a control group...
Article
The aims of present research were to analyze the visually guided eye movements of subjects suffering from the consequences of whiplash injury and the possibility to differentiate patients from feigning subject. We analyzed the role of video-nystagmography for clinical and forensic aspects. It was a prospective case-control study. Detailed history w...
Article
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Autoimmune inner ear disease (AIED) is a rare condition that accounts for less than 1 % of hearing loss or dizziness. Patients generally have aural fullness as well as tinnitus which may precede the hearing loss. One ear is usually involved first and worsens ahead of the contralateral side. Therefore patients may have only unilateral involvement on...
Article
Intratympanic gentamicin injection is the easiest and least invasive treatment available for Menière's disease as compared to other procedures available today. The most important side effect of this therapy however is sensorineural hearing loss primarily at the high frequencies. Ototoxicity of gentamicin begins at the outer hair cells of the basal...
Article
There are two possible ways to deliver drugs in cases of inner ear diseases: via the bloodstream through systemic administration and through the two windows of the inner ear by application into the middle ear cleft. Efforts to find the strategies to deliver drugs to the inner ear are continuously made by Researchers worldwide. This brief descriptio...
Article
Evaluation of clinical and oncological safety of the modified fronto-lateral laryngectomy in the treatment of T1a-b glottic cancer. Retrospective review of charts of patients managed with classical fronto-lateral laryngectomy or with our modified technique using a cervical fascia flap and a false cord flap to reconstruct the defect. No recurrence o...
Article
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Malformations of bony inner ear are rare anomalies occurring in approximately 20% of patients with congenital sensorineural hearing loss. Conductive hearing loss is usually associated with abnormalities of the external and middle ear. Recent reports of patients with lateral semicircular canal malformations indicate inner ear malformations to be ass...
Article
Aim. Endoscopic septoplasty (ES) has become a wide employed surgical technique in the management of nasal septal deviation. Indication to perform such technique are differently reported in literature and no consensus exist about its utilize. Methods. We conducted a retrospective analysis of charts of patients treated by endoscopic sinus surgery in...
Article
The aim of the study is to review the management of petrous apex cholesterol granuloma. The surgical approaches for drainage or total removal and the wait and see policy were analyzed, and outcomes were evaluated. Retrospective charts of 27 patients managed for petrous apex cholesterol granuloma with a minimum follow-up of 12 months were analyzed i...
Article
Review of postoperative morbidity and facial nerve outcomes of cystic vestibular schwannoma (CVS) patients compared with solid vestibular schwannoma (SVS) patients and a proposal for a new CVS classification system. Retrospective review. Tertiary care facility. Ninety-six patients with surgically treated CVS (1998-2008). Outcomes were assessed in a...