Francesca Cardwell

University of Waterloo | UWaterloo · Department of Geography and Environmental Management (Environment)

Objective Lupus nephritis (LN) is a major cause of morbidity and mortality, affecting up to 60% of patients with systemic lupus erythematosus (SLE). The perspectives of patients with SLE have been explored; however, little is known of the lived experiences of patients with LN. Methods Patients aged ≥18 years with biopsy-proven pure or mixed Intern...

Objective Substantial morbidity and mortality affect those with antiphospholipid antibodies (aPLs) and antiphospholipid syndrome (APS), yet patient experiences remain poorly understood. This research investigated patient experiences of aPL/APS diagnosis; effects on daily life; and healthcare and treatment. Methods Patients aged ≥18 years with APS...

Objectives This study aims to determine the independent impact of definitions of remission/low disease activity (LDA) on direct/indirect costs (DCs, ICs) in a multicentre inception cohort. Methods Patients from 31 centres in 10 countries were enrolled within 15 months of diagnosis and assessed annually. Five mutually exclusive disease activity sta...

Objective Lupus nephritis (LN) is one of the most severe manifestations of SLE; however, we know little about the lived experience of LN. This research investigates patient experiences and perspectives of (1) LN diagnosis; (2) living with LN; and (3) LN healthcare and treatment. Methods Patients aged ≥18 years with biopsy-proven pure or mixed Inte...

Objectives We previously reported in a single centre prevalent SLE cohort that antibodies against the cytokinesis-associated protein M-Phase Phosphoprotein 1 (anti-MPP-1) were associated with SLE-related cranial neuropathy (CN), a rare manifestation of neuropsychiatric SLE (NPSLE). The purpose of this study was to assess whether anti-MPP-1 is a bio...

Objective: We conducted an international survey of patients with SLE to assess their access, preference and trust in various health information sources pre-COVID-19 and during the COVID-19 pandemic. Methods: Patients with SLE were recruited from 18 observational cohorts, and patients self-reporting SLE were recruited through five advocacy organi...

While food allergy prevalence has been studied at the national level, we know little of food allergy prevalence or perceptions of prevalence/management at the local level. This paper uses Waterloo Region as a case study to 1) document self-reported individual and household food allergy and sensitivity prevalence at the local level; 2) investigate p...

Cytokine autoantibodies, particularly those directed to type I interferon (T1IFN), have been reported to portend an increased risk of severe COVID-19. Since SLE is one of the conditions historically associated with T1IFN autoantibodies, we sought to determine the prevalence of cytokine autoantibodies in our local cohort of 173 patients with SLE pre...

Background: Limited data exist on the economic burden of food allergy (FA). Objective: To assess FA-related direct (healthcare and out-of-pocket) and indirect (lost productivity) costs and their determinants in Canadian children and adults self-reporting FA. Methods: FA-individuals self-reporting a convincing history and/or physician diagnosis were...

Despite the diverse academic training of health geographers and their capacity to think spatially and temporally when focusing on complexities of people's health in changing environments, career-related concerns have been raised due to the dearth of academic jobs in the sub-discipline. Given these concerns, an understanding of the career aspiration...

Background Despite a growing movement toward a knowledge-user-driven research process, our understanding of the generation, implementation and evaluation of specific approaches in the integrated knowledge translation (iKT) toolbox that aim to engage health and healthcare knowledge users is limited. Health hackathons offer an innovative approach wit...

Introduction Une littérature scientifique de plus en plus volumineuse démontre les avantages à faire participer les utilisateurs de connaissances aux différentes phases du processus de recherche. Nous avons mobilisé une équipe d’intervenants d’horizons variés pour réaliser un programmathon dans le cadre d’un processus d’application des connaissance...

Introduction There is a growing literature demonstrating the benefits of engaging knowledge-users throughout the research process. We engaged a multi-stakeholder team to undertake a hackathon as part of an integrated knowledge translation (iKT) process to develop nonpharmacological interventions to enhance the economic lives of people with systemic...

Objectives: Individuals with systemic lupus erythematosus experience considerable economic challenges. The aim of this research is to qualitatively investigate experiences of the lifecosts (direct and indirect economic costs and beyond) to those with systemic lupus erythematosus in Canada. Methods: Using a biopsychosocial conceptual framework an...

Asthma is common among children worldwide. Although complex, physical activity participation is important in asthma management, to decrease chronic disease risk, and to facilitate healthy lifestyles for children. Team sport participation is a common way for children to engage in physical activity, but the spaces in which team sport is experienced c...

The environment, broadly defined, plays a significant role in shaping human health. Understanding how environmental health risks are perceived by different people, in different places, and at different times is critical to their management. Using a place-based conceptual framework, this research investigates asthma risk perception determinants and...

Food allergy is a growing public health epidemic in Canada, affecting 50 percent of Canadian households either directly or indirectly. Despite the physical, psychosocial and quality of life impacts to those affected, food allergy has recently been ignored in the Canadian policy context. While the complete etiology of food allergy remains unknown, w...

Physical activity can reduce symptoms and improve wellbeing in people who have asthma, and organized sport is one way for children and youth with asthma to engage in exercise. While asthmatic youth may experience a number of barriers to sport participation, healthy physical and social sport environments supported by coaches can help asthmatic youth...

BaCkground: Food allergy is common in children and adolescents in Canada and Western countries. This population is at risk for bullying according to recent studies. oBJeCtives: To determine the presence and characteristics of bullying in children and adolescents with confirmed food allergy in British Columbia, and to investigate the role of bullyin...

Environmental factors, such as outdoor air pollution, are estimated to be responsible for 13 percent of Canada's overall disease burden. This burden can be expected to be even higher among children, due to unique developmental, behavioral, and physiological factors. Understanding how to reduce exposures to protect children from environmental health...

Background Climate change has been described as the biggest global health threat of the 21st century. Typically framed as an environmental issue, some suggest this view has contributed to public ambivalence and hence a lack of public engagement. The lack of understanding of climate change as a significant environmental health risk on the part of th...

Study area demographics [[25]]. See Additional File 1 for an overview of the sociodemographic variables (such as gender, age, education, and median income) of the study area population.

Participant demographic breakdown. See Additional File 2 for a breakdown of the sociodemographic variables (such as the year of birth, gender, marital status, employment status and education) of the research participants (n = 22).

Interview schedule. See Additional File 3 for the interview schedule (including questions and specific probes) used in the research.

Environmental sustainability is increasingly threatened by large-scale changes to the natural environment that could significantly affect human and ecosystem health. In addition, changes to the social, political, economic and physical environment will impact populations globally. Sustainable behaviour change is needed to reduce greenhouse gas emiss...