Florian J Wegehaupt

Florian J Wegehaupt
University of Zurich | UZH · Klinik für Präventivzahnmedizin, Parodontologie und Kariologie

PD Dr. med. dent.

About

114
Publications
20,054
Reads
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1,770
Citations
Additional affiliations
February 2017 - present
University of Zurich
Position
  • Head Division of Preventive Dentistry and Oral Epidemiology
October 2013 - January 2017
University of Zurich
Position
  • Head Division of Cariology
October 2006 - present
Universität Zürich

Publications

Publications (114)
Article
Full-text available
Objective: The aim of this study was to investigate the resulting abrasive dentin wear using abrasive slurries with different RDA values and applying increasing brushing forces. Methods: Forty-five bovine incisors were randomly allocated in three groups (A, B, C, n = 15). One hundred and eighty dentin samples were prepared from these incisors an...
Article
Full-text available
Background Diamond particles have recently been used as abrasives in toothpastes, which raises questions about its abrasive behaviour towards enamel. This study was carried out to investigate the abrasive enamel wear caused by three diamond-loaded toothpastes (Candida White Diamond: CWD, Swiss Smile Diamond Glow: SSDG, Emoform F Diamond: EFD) and t...
Article
Full-text available
Hypselodont (ever-growing) teeth of lagomorphs or rodents have higher wear rates (of a magnitude of mm/week), with compensating growth rates, compared to the non-ever-growing teeth of ungulates (with a magnitude of mm/year). Whether this is due to a fundamental difference in enamel hardness has not been investigated so far. We prepared enamel sampl...
Article
Full-text available
Objective: To investigate the effect of toothbrush bristles end configuration on the abrasive dentine wear at different brushing forces. Material and methods: One hundred and sixty bovine dentine samples were randomized into eight groups (n = 20). Groups (1 to 4) were brushed with tapered-end bristles at 1-, 2-, 3-, and 4-N brushing forces, resp...
Article
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The geometrical properties of toothbrushes play a role in developing abrasive tooth wear and non-carious cervical lesions. This study investigated the interplay between the toothbrush tuft arrangement (crossed vs. parallel) and bristle stiffness (soft vs. medium) on the abrasive dentin wear using three slurries with different levels of abrasivity (...
Article
Purpose To evaluate the influence of pretreatments on microtensile bond strength (μTBS) to eroded dentin when using a universal adhesive in self-etch mode. Materials and Methods Forty-eight human molars were randomly assigned to six groups (G1–G6, n = 8) and ground down until dentin exposure. G2–G6 were eroded with citric acid (pH 2.6) for 10 x 2...
Article
Full-text available
Periodontitis and dental caries are two major bacterially induced, non-communicable diseases that cause the deterioration of oral health, with implications in patients' general health. Early, precise diagnosis and personalized monitoring are essential for the efficient prevention and management of these diseases. Here, we present a disk-shaped micr...
Article
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Purpose: To investigate the effect of energy drinks supplementation with green tea extract on the erosive dentine wear. Materials and methods: Six groups of bovine dentine samples (n = 15) were subjected to four cycles erosive attacks (10 min, 25 °C) and remineralisation (artificial saliva, 60 min, 37°C) using the following formulas: tap water;...
Article
The following article deals with various considerations concerning the frequently observed occurrence of dental erosion in athletes. It summarizes the basics of erosive tooth wear development as well as special etiologic factors for groups of athletes with increased prevalence of dental erosion and concludes with preventive advice. (Originally pub...
Article
The aim of this study was to examine the wear of three different composite materials usable for vertical bite reconstruction under erosive/abrasive conditions and to compare them with the bovine dental hard tissues enamel and dentin in-vitro. The composite materials Filtek Supreme XTE, CeraSmart and Brilliant Crios and bovine enamel and dentin spec...
Article
Full-text available
Objective To investigate the influence of toothbrush bristle stiffness and applied brushing force on the resulting abrasive dentine wear in vitro. Methods One hundred sixty bovine dentine samples were randomly allocated in eight groups (n = 20). Groups one to four were brushed with a soft-bristle toothbrush with soft bristles applying 1, 2, 3 and...
Article
Full-text available
Purpose To evaluate the influence of hydrofluoric acid (HF) contamination on the microtensile bond strength (μTBS) during dental repair procedures before and after application of different dentin adhesives (Optibond FL and Optibond XTR). Materials and Methods Thirty-five human molars were ground down into the dentin and were randomly divided into...
Article
Full-text available
Background This study aims to investigate the influence of different dentin pretreatment procedures on the resulting abrasive dentin wear. Methods Two groups (A, B) of 60 dentin samples each were prepared. Group A was brushed with an abrasive slurry (RDA = 85) and group B with a different abrasive slurry (RDA = 174). Four subgroups in each group (...
Article
Full-text available
Objective This in-vitro study aimed to investigate the effect of a sonic toothbrush on the resulting abrasive dentine wear using toothpastes with different abrasivities compared to the use of a manual toothbrush. Methods Ninety-six bovine dentine samples were divided into six groups and subjected to brushing sequence (sonic: 20 min, 0.9 N, 10 stro...
Article
Full-text available
Background This in-vitro-study aimed to evaluate the potential of different fluoride gels to prevent gastroesophageal reflux induced erosive tooth wear. Methods Surface baseline profiles of a total of 50 bovine enamel specimens [randomly assigned to five groups (G1–5)] were recorded. All specimens were positioned in a custom made artificial oral c...
Article
Full-text available
This study investigated the potential of salivary bacterial and protein markers for evaluating the disease status in healthy individuals or patients with gingivitis or caries. Saliva samples from caries- and gingivitis-free individuals (n = 18), patients with gingivitis (n = 17), or patients with deep caries lesions (n = 38) were collected and anal...
Article
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Enzymes in toothpastes can support host immune responses, and thus maintain oral health. This study aimed to investigate gingival health and the plaque-reducing effects of enzyme-containing toothpastes. A laboratory study tested the antimicrobial potential of different enzyme-containing toothpaste formulations. Two promising formulations (enzyme-co...
Article
Aim of this study was to get an overview of what dentists estimate to be the reason for failure of adhesive composite restorations and to gain knowledge about potential future foci for targeted further education. Therefore, a survey about the fabrication of composite restorations was conducted in the course of seven dental conferences with the main...
Article
Aim of this study was to get an overview of what dentists estimate to be the reason for failure of adhesive composite restorations and to gain knowledge about potential future foci for targeted further education. Therefore, a survey about the fabrication of composite restorations was conducted in the course of seven dental conferences with the main...
Article
Purpose: To determine the impact of the brushing protocol on dentin wear by comparing continuous to intermittent brushing, with the same total time of brushing. Materials and methods: Dentin specimens (n = 120) were evently distributed into six groups (A-F). The samples were brushed with slurries of different relative dentin abrasivity (RDA): Gr...
Article
Full-text available
Purpose: To investigate the possibility of reducing the erosive potential of salad dressings by adding yoghurt. Materials and methods: Two hundred enamel samples from bovine teeth were allocated to 20 groups (n = 10). Three modified commercially available balsamic dressings (addition of 10%, 20%, 50% yoghurt or 8.8 mM calcium chloride) and two h...
Article
Full-text available
Purpose: This in-situ-study investigated if rinsing the oral cavity with a calcium containing solution or a fluoride containing mouthwash immediately before an erosive attack leads to reduced enamel softening. Materials and methods: Bovine enamel samples (n = 240) with measured baseline surface microhardness (KHN) were assigned to five series (S...
Article
Full-text available
Purpose: A previous clinical study showed that the prevalence of erosive toothwear in vegetarians is statistically significantly higher than in nonvegetarians, due to the consumption of vinegar and other acidic foodstuffs. To adequately inform patients, this study investigated the erosive potential of bottled salad dressings available in Switzerl...
Preprint
Full-text available
Background: This in-vitro-study aimed to evaluate the potential of different fluoride gels to prevent gastroesophageal reflux induced erosive tooth wear. Methods: Surface baseline profiles of a total of 50 bovine enamel specimens (randomly assigned to five groups (G1–5)) were recorded. All specimens were positioned in a custom made artificial oral...
Experiment Findings
Full-text available
Aim To assess the distribution and deposition of aerosols during simulated periodontal therapy. Methods A manikin with simulated fluorescein salivation was treated by four experienced dentists applying two different periodontal treatment options, i.e. air-polishing with an airflow device or ultrasonic scaling in the upper and lower anterior front...
Article
Full-text available
Aim: To assess the distribution and deposition of aerosols during simulated periodontal therapy. Methods: A manikin with simulated fluorescein salivation was treated by four experienced dentists applying two different periodontal treatment options, i.e. air-polishing with an airflow device or ultrasonic scaling in the upper and lower anterior front...
Article
Full-text available
It has been speculated that the diluent used to test toothpaste abrasivity in standard tests may have an impact on their results, especially in the context of acidic toothpastes. This study tested whether an acidic toothpaste is indeed more abrasive than a neutral counterpart of otherwise identical composition, and whether this increased abrasivity...
Article
Full-text available
Background & aims: Oral nutritional supplements (ONS) administered to malnourished elders and other patients contain high-levels of carbohydrates that could be a potential risk factor for dental caries. This study aimed to evaluate the cariogenic potentials of ONS using intraoral plaque telemetry. Methods: Ten ONS were tested on five healthy volun...
Article
Full-text available
Objectives: This in vitro study aimed to evaluate and compare the effect of two different bioactive glasses, a hydroxyapatite-containing, fluoride-free toothpaste (HTP) and a fluoride toothpaste (FTP) on the remineralization behavior of initial caries lesions. Materials and methods: A total of 100 bovine enamel samples were randomly allocated to...
Article
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Oral health is maintained by a healthy microbiome, which can be monitored by state-of-the art diagnostics. Therefore, this study evaluated the presence and quantity of ten oral disease-associated taxa (P. gingivalis, T. forsythia, T. denticola, F. nucleatum, C. rectus, P. intermedia, A. actinomycetemcomitans, S. mutans, S. sobrinus, oral associated...
Article
This article will provide an overview of the principles and modes of action of fluorides in oral care products, followed by a brief outline of the history and current situation regarding salt fluoridation in Switzerland. Recommendations for the use of fluoridated oral care products, current research results on the use of fluoride-containing dental...
Article
This article will provide an overview of the principles and modes of action of fluorides in oral care products, followed by a brief outline of the history and current situation regarding salt fluoridation in Switzerland. Recommendations for the use of fluoridated oral care products, current research results on the use of fluoride-containing dental...
Article
Full-text available
Purpose: To investigate whether toothpastes with diamond powder vs those with traditional abrasives abrade dentin and enamel differently and to determine the relative dentin abrasivity (RDA) and relative enamel abrasivity (REA) values of those toothpastes. Materials and methods: Dentin and enamel samples of bovine permanent incisors were randoml...
Article
Full-text available
PURPOSE To investigate dentin abrasivity and cleaning efficacy of novel/alternative toothpastes containing diamond particles, active carbon, sea salt or organic oils. MATERIALS AND METHODS Seventy-two bovine dentin samples (for measuring abrasivity) and 60 human dentin samples (for assessing cleaning efficacy) were used in this study. Samples were...
Article
Full-text available
This study aimed to investigate whether interdental brush shape influences cleaning efficacy, by comparing a waist-shaped interdental brush (W-IDB) with a cylindrical IDB (C-IDB); both provided with the same bristle texture. Cleaning efficacy of differently shaped IDBs was measured in proximal surfaces of teeth in a split-mouth cross-over design. T...
Article
Objective The aim of this study was to evaluate and compare surface roughness, gloss, and color change of dental enamel after being brushed with toothpastes containing diamond powder and traditional abrasives. Materials and Methods Seventy enamel slabs were derived from 70 bovine incisors. The slabs were brushed with six different toothpastes and...
Article
Full-text available
Purpose: To investigate dental enamel wear caused by erosion and abrasion while using a combination of anti-erosive toothbrush/-paste. Materials and methods: A total of 60 enamel specimens from bovine incisors were randomly assigned into five groups of 12 specimens each (G1-5, n = 12): (G1) control group (no treatment), (G2) standard medium toot...
Article
Objective: Aim of this in vitro study was to investigate erosive tooth loss in dependence of the enamel surface structure and presence of an acquired pellicle. Methods: Enamel specimens from 19 bovine incisors (4 specimens/incisor) were allocated to four experimental groups (n = 19). The surfaces of half of the specimens were polished (two group...
Article
Objectives: This in situ study aimed to evaluate whether rinsing with a calcium-containing solution prior to an erosive attack reduces the softening of enamel. Materials and methods: A total of 240 bovine enamel samples with determined baseline surface microhardness (KHN) were allocated to 5 runs in which each of the 12 volunteers performed the...
Article
This review assessed defined specific areas of diagnostic, prophylactic and therapeutic procedures in the field of preventive and restorative dentistry and determined the prevalence and risk of bacteremia, given the assumption that any direct or indirect manipulation of perfused dental and periodontal tissues may lead to bacterial access to the sys...
Article
Full-text available
This review assessed defined specific areas of diagnostic, prophylactic and therapeutic procedures in the field of preventive and restorative dentistry and determined the prevalence and risk of bacteremia, given the assumption that any direct or indirect manipulation of perfused dental and periodontal tissues may lead to bacterial access to the sys...
Article
Full-text available
To assess the remineralizing potential of dentin matrix proteins and enamel matrix derivatives (DMPs and EMDs) after application on artificially induced dentin lesions, given the hypothesis that these materials increase the mineral uptake, binding, and mineralization. Forty-eight caries-free human premolars were used. Teeth were cut, polished, and...
Article
Objectives: The study evaluated the suitability of pure crystalline hydroxyapatite (HA) as a substitute for human (H) and bovine (B) enamel in erosion experiments. Methods: Human and bovine enamel and hydroxyapatite specimens (n = 18 each) were submitted to demineralisation by HCl at pH values of 3.0, 2.6 and 2.0 (1.0, 2.5, and 10 mmol/l concent...
Article
Tooth Erosions Associated with Gastroesophageal Reflux: Cause, Prevention and Restorative Therapy Abstract. Dental erosions are caused by the recurring contact of solutions which are unsaturated in tooth minerals,ith hard tooth substances. This initially leads to softening and later to an irreversible loss of hard tooth substance. Erosion is observ...
Article
Nichtkariöse Zahnhartsubstanzverluste wie Erosionen und Abrasionen sind kein neues, noch nie dagewesenes Phänomen. Dass sie nun mehr in den Mittelpunkt des Interesses rücken und als relevantes Problem wahrgenommen werden, hängt vielmehr mit dem erfolgreichen Kariesrückgang der letzten Jahrzehnte zusammen. Ziel des vorliegenden Artikels ist es, nich...
Article
Full-text available
We compared the prevention of erosive and erosive/abrasive enamel loss by a medical minerals gel system (R.O.C.S.) to that by an anti-erosive toothpaste. Seventy-two bovine enamel samples were randomly allocated to six groups (E1–E3 and EA1–EA3; n=12). Per day, samples were eroded (2 min) 9 times using HCl (pH 2.6). Between erosive challenges and o...
Article
It was the aim of the current in vitro study to test the erosion-preventive potential of an experimental surface sealant (K-0184) and currently marketed self-etch adhesive systems under abrasive conditions. Ninety-six dentine specimens were randomly allocated to eight groups (n=12): (1) positive control (no treatment), (2) K-0184, (3) Shield Force...
Article
Eroded enamel is more susceptible to abrasive wear than sound enamel. New toothpastes utilizing diamond particles as abrasives have been developed. The present study investigated the abrasive wear of eroded enamel by three commercially available toothpastes (one containing diamond particles) and compared it to the respective wear of sound enamel ca...
Article
Purpose: To evaluate the influence of different pretreatments on the microtensile bond strength (μTBS) of an etchand- rinse adhesive to eroded dentin. Materials and methods: Thirty-six human teeth were ground down to their dentin layer and randomly divided into six groups (G1-G6; n = 6), G1 being the control group. Only in the test groups (G2-G6...
Article
Full-text available
The aim of this study was to carry out a representative survey on the implementation of and experience with repairs of single-tooth restorations among dentists in the Canton of Zurich, Switzerland. An anonymous questionnaire was sent to all 1,411 dentists registered in the Canton of Zurich; 38.9% of the delivered questionnaires were returned and 35...
Article
Purpose: To determine whether reducing the light-curing time of resin-based surface sealants influences their potential to prevent erosion, as well as their mechanical stability and degree of conversion. Materials and methods: 240 bovine dentin samples were randomly divided into 10 groups (1-10). The 24 samples of one group remained unsealed and...
Article
It should be the aim of modern dentistry to diagnose possible diseases as early as possible, to eli-minate the causative factors and to initiate non-and/or minimalinvasive treatment options, where ever possible. Especially the induction of remineralisation and where possible the support of remineralisation of initial defects by the application of r...
Article
Full-text available
This study analyzed the anti-erosive effect of a self-assembling peptide fibre gel. One hundred and twelve bovine enamel samples were ground flat and subjected to a three times de- and re-mineralization cycle: erosion (5min, HCl, pH2.6) alternated with storage in artificial saliva under agitation. Then, samples were covered with dif-ferent anti-ero...
Article
Full-text available
Background: The degree of conversion (DC) of resin based materials depends, beside other factors, on the light-intensity applied during light curing. A lower DC might be correlated with an increased cytotoxicity of the respective materials. Therefore, aim of the present study was to investigate the influence of the distance between light-curing ti...
Article
The condition of dental erosion is defined as acid-related loss of tooth structure which does not involve microorganisms. Depending on the origin of the acid, extrinsic (usually caused by acids in food) and intrinsic (caused by endogenous acid) erosion can be distinguished. The presence and severity of erosive defects depend on various parameters s...
Article
Full-text available
Objectives To assess the re-hardening potential of enamel matrix derivatives (EMD) and self-assembling peptides in vitro, hypothesizing that these materials may increase the mineralization of artificial carious lesions and improve hardness profiles. Material and Methods Forty-eight enamel samples were prepared from extracted bovine lower central i...
Article
The extrinsic sources for erosion-causing acids are primarily acidic beverages and foodstuffs. Effervescent tablets also contain organic acids (e.g. citric, tartaric, malic) in order to form carbon dioxide by contact with water – with the help of the carbonate salts of the tablets. To adequately inform patients about the possible erosive potential...
Article
Global healthcare systems are struggling with the enormous burden associated with infectious diseases, as well as the incessant rise of antimicrobial resistance. In order to adequately address these issues, there is an urgent need for rapid and accurate infectious disease diagnostics. The H2020 project DIAGORAS aims at diagnosing oral and respirato...
Article
Full-text available
Global healthcare systems are struggling with the enormous burden associated with infectious diseases, as well as the incessant rise of antimicrobial resistance. In order to adequately address these issues, there is an urgent need for rapid and accurate infectious disease diagnostics. The H2020 project DIAGORAS aims at diagnosing oral and respirato...
Article
Ziel des Beitrags ist es, einen Überblick über die aktuelle Studienlage zur Verwendung von Oberflächenversieglern und Dentinadhäsiven zum Schutz vor erosivem Zahnhartsubstanzverlust zu geben. Hierzu werden die vorhandenen In-vitro-, In-situ- und In-vivo-Studien kurz vorgestellt und die wichtigsten Resultate referiert. Des Weiteren wird auf Untersuc...
Article
Der Begriff der dentalen Erosion bezeichnet den säurebedingten Zahnhartsubstanzverlust, welcher ohne Mitbeteiligung von Mikroorganismen entsteht. In Abhängigkeit vom Ursprung der Säuren wird zwischen extrinsischen (meistens verursacht durch Säuren in Lebensmitteln) und intrinsischen (verursacht durch körpereigene Säure) Erosionen unterschieden. Das...
Article
Die folgende Übersicht stellt den Einsatz direkter und indirekter Kompositrestaurationen zur Rekonstruktion erosiv stark veränderter Gebisssituationen dar. Es wird zudem eine Einschätzung der zur Verfügung stehenden Kompositmaterialien für diese Indikation vermittelt.
Article
Objectives: This study investigated the influence of proximal box elevation (PBE) with composite resin when applied to deep proximal defects in root-filled molars with mesio-occluso-distal (MOD) cavities, which were subsequently restored with computer-aided designed/computer-aided manufacturing (CAD/CAM) ceramic or composite restorations. Materia...
Conference Paper
Objective: Aim of the present study was to investigate the erosive potential of seven commercially available vitamin+mineral effervescent-tablets (ET). Method: Ninety-six bovine enamel samples were prepared and randomly assigned to eight groups (G1-G8). Per cycle, samples (n=12/group) were immersed (2 min) in solution (10 ml/sample) freshly prepa...
Article
Purpose: To determine the influence of the relative enamel abrasivity (REA) of fluoridated toothpaste on the uptake of KOH-soluble and structurally bound fluoride into enamel. Materials and methods: Bovine enamel samples were randomly allocated to 6 groups (n = 36 per group). Groups A to C were treated with sodium fluoride (NaF) toothpastes and...
Article
Full-text available
Objective: To test the stability of two conventional adhesives when combined with a low-viscosity caries infiltrant used for sealing sound enamel against toothbrush abrasion and acid challenge in vitro. Materials and methods: Bovine enamel discs (Ø = 3 mm) randomly assigned to three groups (n = 10/group) were etched with 37% phosphoric acid for...