Florence Perquier

Centre for Addiction and Mental Health · Cundill Centre for Child and Youth Depression

Parenting can protect against the development of, or increase risk for, child psychopathology; however, it is unclear if parenting is related to psychopathology symptoms in a specific domain, or to broad liability for psychopathology. Parenting differs between and within families, and both overall family-level parenting and the child-specific paren...

Background Although there is an increasing number of adults older than 60 years old (>60) suffering from psychiatric disorders, there are only few studies about elderly patients in psychiatric emergencies, and no European data. The goal of our study is to describe the population of patients > 60 consulting in the most important French emergency psy...

There is a need for reliable and valid screening tools that assess depressive symptoms in adolescents in Pakistan. To address this need, the present study examined the psychometric properties and factor structure of a Sindhi-translated and adapted version of the child-report Mood and Feelings Questionnaire (MFQ-C) and the Short Mood and Feelings Qu...

Parenting can protect against the development of, or increase risk for, child psychopathology; however, it is unclear if parenting is related to psychopathology symptoms in a specific domain, or to broad liability for psychopathology. Parenting differs between and within families, and both overall family-level parenting and the specific parenting a...

Background: Intensive longitudinal data collection, including ecological momentary assessment (EMA), has the potential to reduce recall biases and increase our understanding of dynamic associations between variables. Cost and privacy concerns represent barriers that may limit the use of EMA. Research Electronic Data Capture (REDCap), a freely avail...

Background and objectives Early detection of psychiatric disorders in general hospital settings could facilitate a systematic assessment of anxiety and depression, and lessen their non-detection, misdiagnoses and subsequent negative impacts. We built a new short screening tool with simple Yes/No questions on anxiety and depression and examined its...

Background: Migrants, and particularly asylum seekers, are at increased risk of psychiatric disorders in comparison with natives. At the same time, inequalities in access to mental health care are observed. Methods: In order to evaluate whether the Parisian public psychiatric system is optimally structured to meet the needs of this population, w...

Background: Suicide is a leading cause of death in children and youth, with suicidal thoughts and suicide attempt (referred to as non-fatal suicidal behaviors; NFSB) being among its strongest predictors. Parenting, including positive parenting (e.g. warmth, responsiveness), negative parenting (e.g. control, hostility) and parent-child relationship...

Employment rate in psychiatry is around 10 to 30%. Cognitive remediation (CR) associated with psychosocial rehabilitation shows good functional outcomes, with a high level of satisfaction in participants provided by tailored CR. However, few studies looked at the long-term outcome in participants who experienced such a program. This retrospective s...

Introduction Les objectifs de notre étude étaient de valider la version française de la Binge Eating Scale (BES) et de l’évaluer comme outil de dépistage du Binge Eating Disorder (BED) dans une population de consultation de chirurgie bariatrique où le BED est fréquent et impacte le pronostic post-chirurgical à long terme. Matériel et méthode Entre...

Résumé Introduction La loi du 5 juillet 2011 réformée a profondément modifié les modalités de l’hospitalisation sans consentement en psychiatrie, introduisant notamment les Admissions en Soins Psychiatriques en Péril Imminent (ASPPI) sans tiers, qui devaient rester l’exception, mais dont la prévalence n’a cessé d’augmenter. L’objectif de notre étu...

Résumé Au niveau international, la pratique avancée a su s’intégrer au sein de nombreux systèmes de santé depuis les années 1960, toutefois, en France, sa reconnaissance n’est que récente avec la promulgation de la loi du 26 janvier 2016, dont les textes et décrets viennent juste de paraître. Or, le contexte sanitaire français accuse depuis un cert...

Résumé Objectif Notre étude propose une estimation standardisée des comorbidités addictives dans une population de patients souffrant de schizophrénie suivis en centre médico-psychologique adulte. Méthode Une évaluation des conduites addictives a été menée auprès de 106 patients schizophrènes suivis en ambulatoire par des structures de psychiatri...

CITATIONS 0 READS 155 3 authors: Some of the authors of this publication are also working on these related projects: identification of skill for teachers in nursing sciences across europe View project ethics and law in heath care View project Jane-laure Danan Metropole du grand-nancy

Background The association between migration and psychosis is well established in many European countries (Jongsma et al., 2017). However, this risk varies across the different ethnic groups and countries, suggesting the role of life events related to the migration process and social adversity in the host country (Bhugra, 2004). Migration in France...

Background Increased incidence and prevalence of severe mental disorders (especially psychosis) are reported among migrants in Europe (Jongsma et al., 2017). However, there is evidence that pathways to care and service use are not similar between these groups (Bhui et al., 2003). Paris has about 2 million inhabitants including 20% of migrants. A pr...

Introduction Les troubles psychiques ou liés à la consommation de substances restent sous-estimés chez les patients se présentant aux services d’accueil des urgences (SAU) [1,2,3]. L’utilisation d’échelles psychométriques présente des limites dans ce contexte. Nous avons souhaité évaluer l’apport d’un nouvel outil conçu sous la forme d’une liste de...

Introduction l’OMS mentionne qu’environ 15 % des adultes âgés de plus de 60 ans, souffrent d’un trouble mental. Certaines études estiment que ce sont plus de la moitié des sujets de plus de 65 ans qui souffriraient d’un trouble psychiatrique (Rigaud et al. 2005). Objectif L’objectif principal de notre recherche a été de mesurer le score d’Alliance...

Introduction: General practitioners (GPs) play a significant role in detecting emerging psychiatric disorders in young adults aged 15 to 25, including psychosis. The way they screen and refer these patients has rarely been investigated in France. Objectives: To estimate the proportion of GPs who had ever seen young patients with symptoms of psychos...

Background Asylum seeker status is associated to higher prevalence of psychiatric disorders due to not only pre-migration events but also to the trajectory of migration and post- migration adversities. Mental problems and need of care may vary according to these different stages. In France, after the cleaning of the “Calais jungle” in October 2016,...

Introduction Homeless people are more likely to have higher prevalence of psychotic disorders than general population. However, we know less about the prevalence of psychotic symptoms in this group. Objectives To estimate the lifetime and current prevalence of psychotic symptoms and their correlates among homeless people living in the Paris metrop...

Introduction L’elaboration d’un diagnostic territorial de sante mentale requiert une description prealable de l’organisation des soins et des pratiques en psychiatrie. Le CH Sainte-Anne, l’EPS Maison-Blanche, le GPS Perray-Vaucluse, l’Association de sante mentale du 13e arrondissement et les hopitaux de Saint-Maurice desservent l’ensemble des secte...

Among patients examined after a suicide attempt in a Parisian emergency department, we aimed to compare individual characteristics of i) first time and multiple suicide attempters, ii) attempters whose principal motive was “to die” and attempters who had any other motive. Information regarding sociodemographics, clinical characteristics, prior ment...

Objectives: Binge drinking is widespread in medical students but is poorly studied in France. The aim was to evaluate the number of binge drinking episodes and to better characterize them among a sample of French medical students. Methods: We carried out a cross-sectional study at Paris VII's Faculty of Medicine. Through a brief self-questionnai...

Background: Intake of flavonoid-containing food has been shown to have a beneficial effect on blood pressure in short-term randomized trials. There are limited data on total flavonoid and flavonoid-subclass consumption over a long period of time and the corresponding incidence of hypertension. Objective: We aimed to evaluate the relation between...

Background: Carotenoids and vitamin C are thought to be associated with reduced cancer risk because of their antioxidative capacity. Objective: This study evaluated the associations of plasma carotenoid, retinol, tocopherol, and vitamin C concentrations and risk of breast cancer. Design: In a nested case-control study within the European Prosp...

Introduction: Specific coffee subtypes and tea may impact risk of pre- and post-menopausal breast cancer differently. We investigated the association between coffee (total, caffeinated, decaffeinated) and tea intake and risk of breast cancer. Methods: A total of 335,060 women participating in the European Prospective Investigation into Nutrition...

Objective: To assess the association of body-size from childhood to age 40 with depression in postmenopausal French women. Methods: Participants of the E3N study reported birth characteristics and silhouettes matching theirs at age 8, at puberty, at 20-25, and 35-40 years (n = 41,144). Depression was assessed by the Center for Epidemiological St...

Background – Depression is the most common mental disorder, but its etiology and associated risk factors in postmenopausal women remains largely unknown. A relationship between hormonal or anthropometric factors and severe depressive symptoms (SDS) has been suggested but could vary according to whether postmenopausal SDS are preceded by a psycholog...

Dietary flavanols and flavonols, flavonoid subclasses, have been recently associated with a lower risk of type 2 diabetes (T2D) in Europe. Even within the same subclass, flavonoids may differ considerably in bioavailability and bioactivity. We aimed to examine the association between individual flavanol and flavonol intakes and risk of developing T...

Introduction Les études précédentes ont suggéré une association positive entre la dépression et le surpoids et/ou l’obésité notamment au sein de populations nord-américaines [2]. Notre objectif était d’identifier les associations transversales entre la dépression primo-incidente ou récurrente et différentes mesures anthropométriques au sein d’une p...

Introduction Une forte corpulence dans l’enfance ou l’adolescence pourrait influencer le risque de dépression chez l’adulte indépendamment de l’indice de masse corporelle à l’âge adulte [1,2]. Notre objectif était d’identifier chez des femmes françaises post-ménopausées l’association entre la corpulence à la naissance, dans l’enfance et au cours de...

This study aims to identify reproductive factors associated with severe depressive symptoms (SDS) in postmenopausal women and to determine whether a past psychological disorder (PPD) and the timing of first-onset PPD in relation to menopause modify associations. Lifetime reproductive characteristics and PPD were obtained from 51,088 postmenopausal...

OBJECTIVE To study the association between dietary flavonoid and lignan intakes, and the risk of development of type 2 diabetes among European populations.RESEARCH DESIGN AND METHODS The European Prospective Investigation into Cancer and Nutrition-InterAct case-cohort study included 12,403 incident type 2 diabetes cases and a stratified subcohort o...

Limited epidemiological evidence suggests a protective role for plant foods rich in flavonoids and antioxidants in hepatocellular cancer (HCC) aetiology. Our aim was to prospectively investigate the association between dietary intake of flavonoids, lignans and non enzymatic antioxidant capacity (NEAC) and HCC risk. Data analysed were from the Europ...

We prospectively investigated dietary flavonoid intake and esophageal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. The study included 477,312 adult subjects from 10 European countries. At baseline, country-specific validated dietary questionnaires were used. During a mean follow-up of 11 years (1992...

Thearubigins (TR) are polymeric flavanol-derived compounds formed during the fermentation of tea leaves. Comprising ∼70% of total polyphenols in black tea, TR may contribute majorly to its beneficial effects on health. To date, there is no appropriate food composition data on TR, although several studies have used data from the US Department of Agr...

Evidence on the association between dietary flavonoids and lignans and breast cancer (BC) risk is inconclusive, with the possible exception of isoflavones in Asian countries. Therefore, we investigated prospectively dietary total and subclasses of flavonoid and lignan intake and BC risk according to menopause and hormonal receptor status in the Eur...

Phenolic acids are secondary plant metabolites that may have protective effects against oxidative stress, inflammation and cancer in experimental studies. To date, limited data exist on the quantitative intake of phenolic acids. We estimated the intake of phenolic acids and their food sources and associated lifestyle factors in the European Prospec...

The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. 373,803 subjects aged 25-70 years were recruited in 10 European countries (1992-2000) in the PANACEA project of the EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and weight and height were...

Different lifestyle patterns across Europe may influence plasma concentrations of B-vitamins and one-carbon metabolites and their relation to chronic disease. Comparison of published data on one-carbon metabolites in Western European regions is difficult due to differences in sampling procedures and analytical methods between studies. The present s...

Background: Several experimental studies have suggested potential anticarcinogenic effects of flavonoids, although epidemiologic evidence for the impact of dietary flavonoids on risk of gastric cancer (GC) is limited. Objective: We investigated the association between intake of dietary flavonoids and lignans and incident GC. Design: The study...

A greater adherence to the traditional Mediterranean (MED) diet is associated with a reduced risk of developing chronic diseases. This dietary pattern is based on higher consumption of plant products that are rich in flavonoids. We compared the total flavonoid dietary intakes, their food sources and various lifestyle factors between MED and non-MED...

Published associations between dietary carotenoids and vitamin C and bladder cancer risk are inconsistent. Biomarkers may provide more accurate measures of nutrient status. We investigated the association between plasma carotenoids and vitamin C and risk of urothelial cell carcinoma (UCC) in a case-control study nested within the European Prospecti...

Previous studies have shown that high fiber intake is associated with lower mortality. However, little is known about the association of dietary fiber with specific causes of death other than cardiovascular disease (CVD). The aim of this study was to assess the relation between fiber intake, mortality, and cause-specific mortality in a large Europe...

In 2007 the World Cancer Research Fund (WCRF) and the American Institute of Cancer Research (AICR) issued 8 recommendations (plus 2 special recommendations) on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. We aimed to investigate whether concordance with...

Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifes...

Epidemiological studies suggest health-protective effects of flavan-3-ols and their derived compounds on chronic diseases. The present study aimed to estimate dietary flavan-3-ol, proanthocyanidin (PA) and theaflavin intakes, their food sources and potential determinants in the European Prospective Investigation into Cancer and Nutrition (EPIC) cal...