Flavio D'Abramo

Flavio D'Abramo
Max Planck Institute for the History of Science | MPIWG · Lise Meitner Research Group "China in the Global System of Science"

Dr. Phil.

About

33
Publications
6,404
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413
Citations
Citations since 2016
20 Research Items
402 Citations
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2016201720182019202020212022020406080
2016201720182019202020212022020406080
2016201720182019202020212022020406080
Additional affiliations
April 2012 - September 2013
Ruhr-Universität Bochum
Position
  • PostDoc Position

Publications

Publications (33)
Article
Full-text available
The field of epigenetics is leading to new conceptualizations of the role of environmental factors in health and genetic disease. Although more evidence is required, epigenetic mechanisms are being implicated in the link between low socioeconomic status and poor health status. Epigenetic phenomena work in a number of ways: they can be established e...
Article
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This article traces the historical co‐evolution of microbiology, bacteriology, and virology, framed within industrial and agricultural contexts, as well as their role in colonial and national history between the end of the 19th century and the first decades of the 20th century. The epistemology of germ theory, coupled with the economic interests of...
Article
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The establishment of international sanitary institutions, which took place in the context of rivalry among the great European powers and their colonial expansion in Asia, allowed for the development of administrative systems of international epidemiological surveillance as a response to the cholera epidemics at the end of the nineteenth century. In...
Article
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The industrialisation of food production over the past century has triggered a series of sanitary crises related to antibiotic resistance. In this article, I contend that to understand the radical transformation of animal farming and its effects on public health, we need to inquire into the historical development of the knowledge on microbes, espec...
Article
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What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? This qualitative historical study addresses this question by situating the experiences, hopes, and reasons of patients to enter clinical trials within the historical trajectory of informed consent and monoclonal anti...
Article
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Today, claims about the contiguity of health management and societal organization bring biopolitical concerns to the forefront. This essay offers historical-political insights on the covid-19 pandemic, which are particularly urgent, as both the temporal and the cultural-political dimensions have been insufficiently considered in current debates. Af...
Chapter
Ivan I. Schmalhausen (1884–1963) was a Ukrainian geneticist and zoologist nowadays recognized as a central figure in the development of the modern evolutionary synthesis. He studied with Alexey Nikolaevich Severtsov, a leading biologist and the founder of the Russian school of evolutionary morphology, who made relevant contributions in the field of...
Article
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In this paper I consider the inception of molecular biology as a way of illustrating how institutions developed in the twentieth century in reaction to the sublime, horrific terror elicited by the finitude and unpredictability of our bodies and will. The molecular biology program of the Rockefeller Foundation, which drew on D’Arcy Wentworth Thompso...
Book
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ll volume introduce il lettore all’epigenetica, lo studio biologico della continuità tra organismi e ambienti, attraverso la sua storia e le sue attuali applicazioni nella salute pubblica e nella ricerca scientifica. Sulla scia della divisione del mondo nei blocchi delineati durante la guerra fredda, l’epigenetica venne osteggiata dalle più importa...
Article
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Millions of people worldwide currently suffer from serious neurological diseases and injuries for which there are few, and often no, effective treatments. The paucity of effective interventions is, no doubt, due in large part to the complexity of the disorders, as well as our currently limited understanding of their pathophysiology. The bleak pictu...
Article
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Background Innovations in technology have contributed to rapid changes in the way that modern biomedical research is carried out. Researchers are increasingly required to endorse adaptive and flexible approaches to accommodate these innovations and comply with ethical, legal and regulatory requirements. This paper explores how Dynamic Consent may p...
Article
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Donation of human tissues for research and ELSI (ethical, legal, and social issues) of biobanking are increasingly debated issues. While several studies have highlighted patients' concerns, little is known about opinions and preferences of healthy potential donors. Further investigations in this respect may allow communication procedures tailored t...
Article
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Background: There is growing consensus that individual genetic research results that are scientifically robust, analytically valid, and clinically actionable should be offered to research participants. However, the general practice in European research projects is that results are usually not provided to research participants for many reasons. Thi...
Article
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Personalized medicine is a new field based on molecular biology and genomics in which targeted tumor therapies are administered to patients. Psycho-oncology is a complementary approach that considers social and psychological aspects of patients as part of the treatments for cancer patients. The aim of this mini-review is to weigh clinical benefits...
Article
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Biobanks, which contain human biological samples and/or data, provide a crucial contribution to the progress of biomedical research. However, the effective and efficient use of biobank resources depends on their accessibility. In fact, making bio-resources promptly accessible to everybody may increase the benefits for society. Furthermore, optimizi...
Article
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Background Appropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been conducted to gather experiences, preferences and views of patients, healthy research participants and further stakeholders. However, th...
Article
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In biobank research, one of the main obstacles for full applicability of Open Access to biomedical resources is the researchers’ reluctance to make immediately and freely available these materials before having adequately exploited their potential. To analyse this issue from a wider perspective, we need to consider the role of research biobanks as...
Article
Full-text available
Biobanks hold human biological samples and/or data giving a crucial contribution to the progress of biomedical research. However, the effective and efficient exploitation of these resources depends on their accessibility. In fact, making bio-resources promptly accessible to all, can favour collaboration among research groups as well as multidiscipl...
Article
Full-text available
Biobanks hold human biological samples and/or data giving a crucial contribution to the progress of biomedical research. However, the effective and efficient exploitation of these resources depends on their accessibility. In fact, making bio-resources promptly accessible to all, can favour collaboration among research groups as well as multidiscipl...
Article
Full-text available
With the rise of -omics disciplines and biobank research, personal data and biosamples crossing national borders pose new ethical questions. In this article, informed consent, as originally conceived, is shown as not being sufficient to address aims of research and interests of patients any more. Therefore the author has, after having scrutinised i...
Article
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In this paper I describe uses and critical points of informed consent within therapeutic settings. In the first chapter I describe its origin, mainly through Anglosaxon and Deutsches literature. In the second chapter I describe tensions and arguments among paternalistic points of view, 'shared decision making' proposals and request for empowering a...
Conference Paper
Full-text available
In the article some remarks are made on the birth and development of genetics and epigenetics, and in respect of their relationship with environmental factors. If Johannsen’s genotype concept is a reprise of Woltereck’s Norm of Reaction, is also true that the former excluded the important role of environmental factors considered by the latter. Then...
Chapter
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The phenomenon of high cancer mortality has been the key factor in driving drug approval processes and health-care policies. In this paper, we discuss the inconsistencies of the genetic model of cancer as applied in the case of colorectal cancer (CRC). The result of relying on a genetic model of CRC is the approval of cancer drugs based on the inhi...
Chapter
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Climate change has become a reality, and much research on its causes and consequences is currently conducted. To our knowledge, very little attention has been paid to epistemological issues raised by climate change research. Randomized experiments cannot of course be done, so that climate change research needs to be observational, usually spanning...
Article
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In this paper I take into account science and technology as subjected to socio-economical and cultural dynamics. Then I show some cases, such as the genocentric point of view and the neo darwinistic one, where techno-science is mainly a profit-oriented and ideological research. I argue the importance of science in a broad sense: as social and publi...
Article
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