Flares Baratto Filho

• PhD Endodontics
• Professor (Full) at Universidade da Região de Joinville

Objective: To evaluate the impact of dental caries on daily activities, assessed by the Oral Impacts on Daily Performances (OIDP) and Child-OIDP in adolescents. Methods: Studies published in any language mentioning the relationship between dental caries and OIDP or Child-OIDP were included. PubMed, Scopus, Web of Science, LILACS/BBO, and grey liter...

O retratamento, uma tentativa de retificar um tratamento endodôntico realizado inadequadamente, está indicado em casos de tratamentos insatisfatórios, canais não localizados, lesão periapical persistente, suspeita de contaminação por saliva e persistência de sintomas. A intervenção cirúrgica é indicada nos casos em que o retratamento se mostra invi...

The search for health services is influenced by a number of factors. One such factor is social capital, which can be conceptualized as a network of social relationships that can provide individuals and groups with access to resources and support. Objective: The aim of this systematic review was to explore the relationship between social capital and...

Os dentes molares superiores apresentam uma complexidade anatômica notável em virtude das variações nos canais radiculares. Dentre eles, o segundo molar superior comumente apresenta três raízes, porém a literatura também relata algumas variações anatômicas incomuns desse elemento dentário. Objetivo: Apresentar um relato de caso clínico descrevendo...

O manejo de primeiros socorros de um dente traumatizado possui influência direta no seu prognóstico. Em alguns casos, quando ele não é realizado já no local do acidente, aumentam muito as chances de o indivíduo perder o dente em um curto prazo de tempo, em virtude da reabsorção radicular. Daí a necessidade de treinar o maior número de pessoas para...

Fibroblast growth factors (FGFRs) signaling are required for human tooth development. Its dysregulation affects tooth formation and patients with FGFR2 mutations often present dental anomalies in the spectrum of the syndrome. This study aimed to investigate whether genetic polymorphisms in FGFR2 are associated with molar fused roots. The null hypot...

To investigate the association of polymorphisms in the SOD2 (rs5746136, rs10370, and rs4880) and SOD3 (rs2855262, and rs13306703) genes and dental caries in primary dentition. This cross-sectional study included 753 children aged from 2 to 6 years in primary dentition from 33 public preschools in Nova Friburgo, Rio de Janeiro, Brazil. Covariates su...

The aim was to evaluate the association between dental development (dental maturity) and genetic polymorphisms in PTH and genes involved in vitamin D synthesis in a cohort of Brazilian children. This retrospective cross-sectional study was performed on children receiving orthodontic treatment. Patients who had already undergone orthodontic treatmen...

O manejo de primeiros socorros de um dente traumatizado possui influência direta no seu prognóstico. Em alguns casos, quando ele não é realizado já no local do acidente, aumentam muito as chances de o indivíduo perder o dente em um curto prazo de tempo, em virtude da reabsorção radicular. Daí a necessidade de treinar o maior número de pessoas para...

Aim To perform a systematic review to investigate if the use of audio distraction reduces signs of stress and anxiety in paediatric patients undergoing dental treatment. Materials and methods Search was made in electronic databases (MEDLINE, Scopus, Embase, Web of Science, Scielo, BVS, Springer Link, Science Direct, Cochrane Library, and grey lite...

To analyze whether the single-nucleotide polymorphisms (SNPs) in Matrix metalloproteinases 2, 3, and 9 (MMP2, MMP3, and MMP9), Tissue Inhibitor of Metalloproteinases 1 and 2 (TIMP1 and TIMP2), methionine synthase (MTR) and methionine synthase reductase (MTRR) influence delayed deciduous tooth eruption (DDTE). This cross-sectional study included 106...

Background/Objectives: Dental agenesis is the congenital absence of at least one tooth and has been associated with several other developmental dental conditions, such as morphological dental alterations and Carabelli trait. This study sought to investigate whether third molar agenesis is associated with Carabelli traits in permanent molars. Method...

Introduction: The search for health services is influenced by a number of factors. One such factor is social capital, which can be conceptualized as a network of social relationships that can provide individuals and groups with access to resources and support. Objective: The aim of this systematic review was to explore the relationship between soci...

Tooth injuries represent a significant public health concern, particularly among children and adolescents, given their notable prevalence and potential psychosocial and quality- of-life impacts. This study describes a poignant case involving a six-year-and-eightmonth- old child who endured dental trauma leading to accidental avulsion and swallowing...

Objective To evaluate the association between single nucleotide polymorphisms (SNPs) in cyclooxygenase-2 (COX-2) and external apical root resorption (EARR) after orthodontic treatment. Materials and methods This study analyzed the orthodontic records of patients from Regensburg University Hospital and two collaborating private practices. EARR was...

O manejo de primeiros socorros de um dente traumatizado possui influência direta no seu prognóstico. Em alguns casos, quando ele não é realizado já no local do acidente, aumentam muito as chances de o indivíduo perder o dente em um curto prazo de tempo, em virtude da reabsorção radicular. Daí a necessidade de treinar o maior número de pessoas para...

Preventive dentistry has undergone significant advancements in recent years, leading to a shift in the causes of tooth loss. In contrast, dental injury has emerged as the leading cause. Objective: This study presents a case involving multiple dental injuries at the permanent maxillary left central incisor (21) during a 27-year follow-up. Case repor...

The objective of this study was to develop a predictive model using supervised machine learning to determine sex based on the dimensions of the hyoid bone. Lateral cephalometric radiographs of 495 patients were analyzed, collecting the horizontal and vertical dimensions of the hyoid bone, as well as the distance from the hyoid to the mandible. The...

Objectives To predict palatally impacted maxillary canines based on maxilla measurements through supervised machine learning techniques. Materials and Methods The maxilla images from 138 patients were analysed to investigate intermolar width, interpremolar width, interpterygoid width, maxillary length, maxillary width, nasal cavity width and nostr...

Background and objectives: Pulp calcification is associated with many factors and triggers, including individual genetic predisposition and orthodontic forces. This study aimed to investigate whether genetic polymorphisms in epidermal growth factor (EGF), epidermal growth factor receptor (EGFR1), transforming growth factor-beta 1 (TGFβ1), and trans...

Introduction Genetic polymorphisms who disturb the mineral homeostasis during tooth development and eruption are candidate to clarify the molecular mechanisms involved in changes in the tooth eruption chronology. In this study, we evaluate whether the FokI (rs2228570) and BglI (rs739837) polymorphisms in the Vitamin D receptor (VDR) gene are associ...

The chronological age estimation of living individuals is a crucial part of forensic practice and clinical practice, such as in orthodontic treatment. It is well-known that methods for age estimation in living children should be tested on different populations. Ethnic affiliations in Brazil are divided into several major groups depending on the reg...

Introduction: Pulp stones (PS) are calcifications commonly found in the pulp tissue that may be associated with systemic diseases. Objective: To evaluate the association between PS and systemic diseases. Methods: A case-control study with the inclusion of individuals from 18 to 65 years of age, of both sexes. Analysis was made of 1047 digital panor...

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Background The present study aimed to assess the frequency and variation of 13 nonmetric dental crown traits (NDCT) in permanent and primary molars in German orthodontic patients. Methods Dental records from orthodontic patients were screened and evaluated. First and second permanent and primary upper and lower molars (from left and right sides) w...

Raízes fusionadas são unidas por depósitos formados durante a vida ou por alterações no desenvolvimento da bainha epitelial de Hertwig e carecem de uma análise etiológica abrangente na literatura. Objetivo: Explorar a preferência de gênero em molares com raízes fusionadas. Revisão de literatura: Existem diversas anomalias dentárias, ainda com etiol...

Vários tratamentos térmicos de ligas níquel-titânio (NiTi) foram desenvolvidos para melhorar as propriedades mecânicas e o desempenho clínico da terapia endodôntica. Objetivo: Realizar uma revisão sistematizada da literatura sobre a potencialidade dos tratamentos térmicos aplicados às limas endodônticas com ligas de NiTi para aumentar a resistência...

O cuidado odontológico à pessoa com deficiência evoluiu muito nos últimos anos no Brasil, mas ainda está longe de um patamar ideal. Barreiras como manejo, acessibilidade, comorbidades, comportamentais, de comunicação, de educação e financeiras precisam ser superadas. Objetivo: Analisar a quantidade de atendimentos odontológicos hospitalares no Sist...

The present study tested the combination of mandibular and dental dimensions for sex determination using machine learning. Lateral cephalograms and dental casts were used to obtain mandibular and mesio-distal permanent teeth dimensions, respectively. Univariate statistics was used for variables selection for the supervised machine learning model (a...

O objetivo deste estudo foi avaliar a usabilidade e a utilidade do aplicativo (app) Dental Trauma, disponível gratuitamente e em português nas lojas App Store e Play Store. Participaram do estudo estudantes de Odontologia e Cirurgiões-dentistas (CDs) (n = 20). Utilizou-se o teste de Escala de Usabilidade do Sistema (System Usability Scale - SUS) pa...

This study aimed to evaluate the association between single nucleotide polymorphisms (SNPs) in endochondral development-related genes and mandibular condyle shape, size, volume, and symmetry traits. Cone-beam Computed Tomographies and genomic DNA from 118 individuals were evaluated (age range: 15–66 years). Data from twelve 3D landmarks on mandibul...

This study aimed to assess the association between genetic polymorphisms in BMP2 (rs1005464 and rs235768), BMP4 (rs17563), SMAD6 (rs2119261 and rs3934908) and RUNX2 (rs59983488 and rs1200425) and pulp stones (PS). A total of 117 participants, consisting of 63 individuals with PS and 54 without PS, were included. Digital radiographs and a demographi...

Objectives PITX2 is required for mammalian development and single nucleotide polymorphisms (SNPs) in this gene could be involved in dental agenesis and sella turcica patterns. Thus, the present study evaluated the association between SNPs in PITX2 , third molars agenesis and sella turcica phenotypes. Materials and methods The sample consisted of h...

Recent scientific evidence suggests a close relationship between estrogen deficiency and vitamin D- related genes. Estrogen and vitamin D were involved with alterations in odontogenesis and tooth eruption process. Objective: The aim of the present study was to evaluate the influence of estrogen deficiency on the expression of genes related to the a...

Background: Dental fluorosis (DF) is characterized by hypomineralization of tooth enamel caused by ingestion of excessive fluoride during enamel formation. DF phenotype presents different severities, ranging from very mild to severe phenotypes according to the enamel alteration. This dental development alteration is a common disorder worldwide. It...

Supernumerary teeth are an alteration of dental developmental and result in the formation of teeth above the usual number. Epidemiologic studies suggested that patients with dentofacial anomalies and their family members may present an increased risk of developing cancer, including female breast cancer and gynecologic cancers. These observations in...

Objective To investigate the association between single nucleotide polymorphisms in the COX2 gene (rs689466 and rs5275) and local and systemic signs and symptoms of teething. Material and Methods Forty-four pairs of mothers-babies/toddlers were included. Erupted primary teeth were evaluated during clinical examination. Local and systemic signs and...

This case report describes a favorable healing outcome of the immediate management of an oblique tooth root fracture in the middle third concomitant with coronal fragment extrusion in a permanent maxillary left central incisor of a healthy 14-year-old female patient. The clinical exam showed incisal irregularity, local bleeding, increased mobility,...

The aim of this study was to investigate whether there is an association between inducible in single nucleotide polymorphisms in nitric oxide synthase (rs2297518 and rs2779249) and persistent apical periodontitis. A total of 291 Brazilian subjects were included: 125 with signs/symptoms of persistent apical periodontitis and 166 with root canal‐trea...

The aim was to identify the social and biological factors involved in the control and follow-up of patients with Diabetes Mellitus using insulin. Sociodemographic data and data related to the control of Diabetes Mellitus were collected. The geographic information system (GIS) was used for georeferencing analysis. Statistical analysis was performed...

This randomized clinical trial aimed to evaluate the effects of audiovisual distraction using virtual reality glasses during inferior alveolar nerve block in pediatric dental patients. This clinical trial randomly included 20 participants aged 4 to 11 years from a pediatric dentistry clinic to receive anesthesia with or without VR glasses. Behavior...

Oral manifestations following COVID-19 infection can cause discomfort to patients, therefore new treatments must be investigated in order to avoid or minimize this condition. The aim of this study was to report on the use of oxygen therapy in the treatment of COVID-19 oral manifestations. A 22-year-old male patient sought dental care 15 days after...

Background Genetic polymorphisms have been shown to influence several physiological traits, including dental and craniofacial characteristics. Understanding the clinical relevance of genetic polymorphisms in dental practice is crucial to personalize treatment plans and improve treatment outcomes. Objective to evaluate the association between denta...

Challenges imposed by the covid-19 pandemic on the dental education program included adaptations to remote education. The aim of this study was to assess dental students’ perceptions towards the remote learning (e-learning) to preclinical training. Material and methods: One hundred sixty dental students from the second to the fourth year were inclu...

O trauma dentário é considerado um problema de saúde pública em todo o mundo, por conta de sua alta taxa de prevalência, do impacto psicossocial e, na maioria dos casos, do alto custo de tratamento. Sua maior incidência é em crianças e adolescentes, porém adultos também se envolvem em situações que podem levar a injúria. Objetivo: Dentre as injúria...

The final color of dental ceramics depends on different factors such as light source, substrate, and selected material (thickness, contour, and texture). Objective: To report a clinical case in which a predictable protocol is used to optimize the final color of porcelain laminate veneers. Case report: A male patient attended the dental clinic dissa...

Fiber-reinforced prefabricated intraarticular posts have gained popularity due to several favorable characteristics for clinical use compared to metallic intraradicular posts. Aim: To evaluate the light transmission capacity of two types of fiber posts, using two different methods. Materials and Method: The posts were divided into two groups: exper...

Individuals with cerebral palsy (CP) may have cognitive, sensitive, behavioral, communicative, and convulsive disorders. Because defensive reflexes are reduced by CP, the risk of orofacial trauma is greater in these individuals. This study aimed to evaluate the prevalence of orofacial injuries resulting from trauma in patients with CP. This review...

The aim of this study is to evaluate if single nucleotide polymorphisms (SNPs) in WNT6 and WNT10A are associated with the risk of dental pulp calcification in orthodontic patients. This cross-sectional study followed the “Strengthening the Reporting of Genetic Association Studies” (STREGA) guidelines. Panoramic radiographs (pre- and post-orthodonti...

Background: Endodontic diagnosis can be compared to a puzzle, requiring the interpretation of a series of clinical and imaging data. Mobile health, especially mobile application (apps), can assist professionals in endodontic diagnosis. This work aims to evaluate an app - Endo 10 app, designed to assist pulpal and periapical diagnosis based on the...

Background: This study aimed to evaluate the prevalence of retained primary teeth (RPT) associated with delayed permanent tooth eruption and the factors associated with this condition in German children. Methods: This is a cross-sectional retrospective study that evaluated panoramic radiographs from orthodontic patients. The diagnosis of RPT was...

Background This study evaluated if genetic variations in the WNT family members and RUNX2 are associated with craniofacial maturation, investigating dental and skeletal maturity in children and teenagers. Methods Radiographs from pre-orthodontic treatment of Brazilian patients (7 to 17 years-old) were used to assess dental (panoramic radiographs)...

It was verified the association between oral health, quality of life and associated factors in a population in a southern Brazilian city. Cross-sectional study with 373 dwellers of the Ferraria District, Campo Largo, PR, Brazil, that answered a questionnaire with sociodemographic, socioeconomic, quality of life, habits, general and oral health, and...

Aim: To compare the influence of two methods of agitation of endodontics irrigants, by diffusion of calcium hydroxide [Ca(OH)2] through the dentinal tubules, measuring the pH of the medium where they were kept. Methods: Twenty mandibular incisors were prepared using a WaveOne Gold Large file, in a reciprocating movement, and then divided into (n =...

Aim: This study aims to compare the mesiodistal (MD) and buccolingual (BL) tooth crown size (TCS) of adult patients with cleft lip and palate (CL/P) and patients without CL/P. Materials and methods: The sample of this study consisted of 146 adult patients, of both genders, of which 73 were included in the case group (with CL/P) and 73 were inclu...

O tratamento endodôntico visa à regeneração do tecido periapical, comprometido por inflamação na região apical. Em inúmeros casos esse reparo não é observado em virtude de diversos fatores, desde a correta instrumentação mecânica durante o procedimento endodôntico até a qualidade final da restauração. Objetivo: Avaliar os aspectos clínicos e molecu...

A histomorfometria permite um estudo quantitativo da microscopia óssea, a fim de obter parâmetros estruturais e de formação e remodelação óssea. Objetivo: Realizar uma revisão integrativa da literatura e comparar as técnicas de histomorfometria óssea realizada por meio da emblocação da peça óssea em parafina e emblocação da peça óssea em metacrilat...

O conhecimento da anatomia dos canais radiculares é essencial para o sucesso do tratamento endodôntico. Em virtude da sua complexidade e da morfologia da raiz mesiovestibular, o primeiro molar superior tem sido amplamente investigado, entretanto poucos estudos relatam a incidência do canal MV2 na clínica diária com profissionais com diferentes temp...

O desenvolvimento biológico de um indivíduo pode ser determinado pela maturidade dentária, a qual é relacionada com a maturidade esquelética, sendo determinada pelo estágio de formação dental. Objetivo: Correlacionar o método de Hofmann et al. (2016) com os métodos de Demirjian et al. (1973), Cameriere et al. (2006) e a idade cronológica para estim...

White spot lesions are considered to be a major concern in esthetic dentistry. These lesions can be treated with noninvasive to less invasive procedures, which remain a challenge for many clinicians. The treatment of choice should be as minimally invasive as possible and should aim to minimize the color difference between the white spots and the he...

Objective: Many genes and signaling molecules are involved in orthodontic tooth movement, with mechanically and hypoxically stabilized HIF-1α having been shown to play a decisive role in periodontal ligament signaling during orthodontic tooth movement. Thus, this in vitro study aimed to investigate if genetic polymorphisms in HIF1A (Hypoxia-induci...

Objective: Scientific evidence suggests that estrogen deficiency and genetic factors have an influence on the development of the stomatognathic system. This study aimed to evaluate the influence of estrogen deficiency on the gene expression of TNF-alfa, IL-1beta, IL-6 and IL-10 during dental development in a murine model. Material and Methods: Wist...

Introduction: The final color of dental ceramics depends on different factors such as light source, substrate, and selected material (thickness, contour, and texture). Objective: to report a clinical case in which a predictable protocol is used to optimize the final color of porcelain laminate veneers Case report: A male patient attended the dent...

Introduction: The final color of dental ceramics depends on different factors such as light source, substrate, and selected material (thickness, contour, and texture). Objective: to report a clinical case in which a predictable protocol is used to optimize the final color of porcelain laminate veneers Case report:: A male patient attended the dent...

This study aimed to compare the survival of replanted teeth that followed the 2012 or the 2020 International Association of Dental Traumatology (IADT) guidelines. Sixty-two permanent replanted teeth were retrospectively assessed (IADT 2012, n = 45; IADT 2020, n = 17). Five years after replantation (from January 2017 to December 2021), clinical and...

Introduction: The present study aimed to determine the association between single nucleotide polymorphisms (SNPs) in RUNX2, SMAD6, BMP2, and BMP4 genes in relation to tooth-size discrepancy (TSD). Methods: A cross-sectional study of patients undergoing orthodontic treatment measured the mesiodistal width of permanent teeth from pretreatment dental...

Childhood-related obesity and overweight are increasing concerns for the health and well-being of children. Dental caries (decay) is the most prevalent oral disease during childhood, and several studies have suggested that nutritional status and dental caries are associated in children. Therefore, this study aimed to determine the geographic distri...

This study evaluated the association between single‐nucleotide polymorphisms (SNPs) in vitamin‐D‐related genes and the amount of external apical root resorption linked to orthodontic treatment. One hundred and forty‐three individuals were assessed. The amount of external apical root resorption of upper central incisors (EARRinc) and lower first mol...

Objective To perform an overview of systematic reviews (SR) assessing the impact of malocclusion treatments (Orthodontic Treatment — OT and/or Orthodontic Surgical Treatment — OST) on Oral Health-Related Quality of Life (OHRQoL).Materials and methodsA search strategy was conducted in electronic databases until June 7th, 2021, followed by a manual s...

A pandemia de COVID-19 impôs a interrupção de atividades presenciais coletivas e os profissionais de saúde foram os mais afetados, por estarem na linha de frente no combate desta doença. Medidas de biossegurança tiveram que ser redobradas para evitar a propagação do vírus e assim ajudar a controlar a pandemia. Procedimentos que geram aerossóis na O...

Aim: To assess the influence of remnants of filling material on hydroxyl ion diffusion from calcium hydroxide (CH) paste, measured by the pH value, in retreated teeth. Materials and methods: A total of 120 single-rooted extracted teeth were prepared up to a size 35 hand file and filled. For retreatment, the specimens were divided into four group...

A lesão apical está relacionada a progressão de lesões de cárie ou traumatismos dentários, que levam a polpa à inflamação e necrose, resultando, em alguns casos, em perda dentária. Quando persistente, o processo patológico não se reverte sem tratamento adequado. Objetivo: O estudo discorre sobre como, após ocorrer os fenômenos de necrose pulpar, ac...

O SARS-CoV-2 é um vírus que causou grande impacto no mundo. Possui alta transmissibilidade, infectando muitas pessoas em pouco tempo e causando a covid-19, doença que pode ou não ser assintomática. Os sintomas mais comuns são: febre, tosse, dor de cabeça, dor no corpo (muscular), náusea, fadiga, falta de ar ou dificuldade para respirar, diarreia, c...

Objectives To assess the influence of estrogen deficiency on tooth eruption rate (TER) and gene expression of estrogen receptor alpha and beta (ERα and ERβ) in the odontogenic region of teeth with continuous formation in a rat model. Materials and methods Ovariectomies (OVX; n = 25) and sham surgeries (SHAM; n = 25) were performed in female Wistar...

Este estudo teve como objetivo avaliar a penetração intratubular do Bio-C Sealer utilizando microscopia confocal de varredura a laser (CLSM). Sessenta caninos foram divididos em quatro grupos (n = 15): Bio-C Sealer, Endo Sequence BC Sealer, Sealer Plus BC e AH Plus. Três discos de 1 mm de espessura foram obtidos de cada amostra e analisados para de...

Ectodermal dysplasia (ED) is defined as a group of alterations in gene molecular pathways related to the development of ectodermal structures, including the teeth. A 7-year-old boy diagnosed with hypohidrotic ED since the age of 2 was referred for oral rehabilitation. The extraoral examination revealed clinical characteristics compatible with ED: d...

The maxilla is formed by the medial nasal and maxillary processes fusion. The dental lamina develops from 2 origins connecting in the lateral incisor. The maxillary lateral incisor region is often affected by dental anomalies and clefting. It is possible that genes involved in oral cleft could also be associated with a variety of phenotypic variati...

Persistent primary tooth (PPT) is a prevalent clinical condition that occurs when a primary tooth is over-retained beyond the established period of its normal exfoliation time, remaining in the oral cavity. Many factors could be involved in the risk of PPT; therefore, the aim of this study was to evaluate if single nucleotide polymorphisms (SNPs) i...

The study aimed to explore the influence of genetic polymorphisms in ANKK1 and DRD2 on the signs and symptoms of temporomandibular disorder (TMD) in construction workers. This cross-sectional study included only male subjects. All construction workers were healthy and over 18 years age. Illiterate workers and functionally illiterate workers were ex...

Aim: The aim of the study was to compare the ability of three endodontic sealers, Endofill (END), AH Plus (AHP), and Sealer Plus BC (SPB), to penetrate dentinal tubules. Materials and methods: Forty-five human teeth, single-rooted and previously instrumented mandibular premolars, were randomly divided into three experimental groups (n = 15): END...

Background Multiple signaling molecules have been shown to play crucial roles in dental root development. Therefore, we aimed to investigate the prevalence of S-shaped roots and also to investigate, if single nucleotide polymorphisms (SNPs) in BMP2, BMP4 and SMAD6 are associated with this phenotype in humans. Methods This is a cross-sectional phen...

Introdução: A Organização Mundial de Saúde (OMS) alertou uma “Emergência de Saúde Pública de Importância Internacional” ao final do ano de 2019. Devido à Covid-19 estratégias preventivas e limitantes precisaram ser aderidas, como o isolamento e distanciamento social. Este novo problema de saúde pública global que afetou diversas áreas, dentre elas...

Introdução: A avulsão é caracterizada pelo deslocamento do dente para fora da cavidade alveolar, ocasionando danos no ligamento periodontal e na polpa dentária. Seu prognóstico depende das ações imediatas ao acidente, e o reimplante é a melhor forma de devolver função e estética ao paciente. Objetivo: Comparar os três últimos protocolos da Internat...