Fiona Reid

Central Manchester University Hospitals NHS Foundation Trust · Department of Gynaecology (Saint Mary's Hospital)

Introduction and hypothesis: The Variation in Surgical Technique study (VaST), demonstrated the large variation in surgical techniques used in native tissue (NT) anterior pelvic organ prolapse (POP) repairs. However, there are few comparative studies of different surgical techniques. This study was aimed at exploring whether surgical technique inf...

Polypropylene mesh has been widely used in Urogynaecology for the management of prolapse and stress urinary incontinence. Growing recognition of long-term complications has led to the pause on all vaginally inserted mesh within the UK and other countries. These complications include vaginal mesh exposure, visceral perforation and chronic pain. It i...

Introduction and hypothesis: Our aim was to compare the mid-term results of native tissue, biological xenograft and polypropylene mesh surgery for women with vaginal wall prolapse. Methods: A total of 1348 women undergoing primary transvaginal repair of an anterior and/or posterior prolapse were recruited between January 2010 and August 2013 fro...

Pelvic organ prolapse (POP) is a common presenting complaint in gynaecology. In the UK, prolapse accounts for 20% of women on the waiting list for major gynaecological surgery. It is therefore important that clinicians understand how to accurately assess women with prolapse. The aim of this article is to provide a comprehensive description of the a...

Pelvic organ prolapse, urinary, bowel and sexual dysfunction, collectively called pelvic floor dysfunction (PFD) affects 1 in 3 women and has a significant public health impact. The causes of PFD are not fully understood but involve injury to connective tissue and motor nerve during childbirth. Women with PFD also have sensory nerve impairment, and...

Objective: Report complication rates following prolapse surgery using polypropylene mesh inlay, polypropylene mesh kit, biological collagen xenografts and native tissue repairs DESIGN: Secondary analysis of the PROSPECT randomised controlled trial and cohort study. Setting: Thirty-five UK hospitals POPULATION: 2632 women undergoing anterior and/...

Introduction and hypothesis Health literacy underpins informed consent and shared decision-making. In gynaecology, this includes understanding of normal anatomy and urogenital disease. This study evaluated public knowledge of external female genital anatomy and pelvic organ prolapse (POP). Methods A questionnaire study asked participants for their...

Aims: To determine terminology and methods for raising intra-abdominal pressure (IAP) currently used by clinicians to assess pelvic floor dysfunction (PFD) and to measure the effect of these maneuvers on IAP. Methods: Three-hundred questionnaires were distributed at two scientific meetings in the United Kingdom to determine methods clinicians us...

The goal of any incontinence surgery is to restore function and to achieve continence, with minimal transient surgical morbidity and without immediate or long-term complications. The chapter outlines in detail how colposuspension and fascial sling have evolved to reach their current day format. It goes on to summarize the outcome data available for...

Introduction Since the “mesh pause” many women have been referred to our unit to seek help with mesh complications. Previous studies suggest pain improves in 50% of women after mesh excision (1) and some worsen (2). It is unclear who will benefit from mesh excision. The aim of this study is to evaluate our unit’s experience of pain outcomes after m...

Objective: To compare standard (native tissue) repair against synthetic mesh inlays or mesh kits. Design: Randomised controlled trial. Setting: 33 UK hospitals. Population: Women having surgery for recurrent prolapse. Methods: Women recruited using remote randomisation. Main outcome measures: Prolapse symptoms, condition specific quality...

Introduction: Women with pelvic organ prolapse describe vaginal laxity and poor sensation of vaginal tone that does not correlate with anatomical findings. This discrepancy could be explained by altered vaginal sensation and a test that could measure sensation of vaginal tone, transmitted via Aα and Aβ nerve fibers, would further our understanding...

Introduction and hypothesis This was an observational study aiming to determine factors which influence women’s choice of surgery for primary stress urinary incontinence (SUI). Methods Two hundred twelve women undergoing a primary SUI procedure were recruited to this study from 12 hospitals in the north of England. After choosing a procedure, wome...

Introduction The PROSPECT study found that outcomes for native tissue and mesh prolapse repairs are similar but mesh repairs have a 10% risk of exposure. The current UK surgical mesh pause has led to renewed interest in native tissue surgery. Previous studies of native tissue anterior repair surgical techniques have been limited by the questionnair...

Study objective: To show a case of laparoscopic excision of an ovarian ectopic pregnancy and the technique used. Setting: A university hospital (Manchester University Foundation Trust). Patient: A 23-year-old primigravida presentation at 6 weeks of gestation with an ectopic pregnancy. Intervention: A 23-year-old primigravida presentation at...

Pelvic organ prolapse (POP) is a common presenting complaint in gynaecology. In the UK, prolapse accounts for 20% of women on the waiting list for major gynaecological surgery. It is therefore important that clinicians understand how accurately to assess women with prolapse. The aim of this review is to provide a comprehensive description of the as...

Introduction and hypothesis Our aim was to determine the intraoperative feasibility and complication rate of laparoscopic sacrocolpopexy (LSC) in overweight and obese women compared with women of normal weight. Methods This was a retrospective observational cohort study (Canadian Task Force classification II-2) conducted at a tertiary urogyaenocol...

Objectives: Since 2005 the preferred method for surgical treatment of vaginal vault prolapse within the department has been laparoscopic sacrocolpopexy with an ultra-lightweight polypropylene mesh. The study aimed to explore the functional and anatomical outcomes and mesh adverse events of women following this procedure. Study design: All women...

The urinary tract undergoes numerous physiological adaptions in response to pregnancy. These normal adaptions can increase the risk of complications, such as acute infection and urinary retention, which in turn increase the risk of poor outcomes for the pregnancy. Other urogynaecological complications, for example urological injury at caesarean sec...

Objective: Obstetric anal sphincter injury is common but the effect on body image is unreported. The aim of this study was to explore patient perceived changes in body image and other psychological aspects in women attending a perineal follow-up clinic. Study design: This retrospective study analysed women's responses to a self-reported question...

Introduction and hypothesisEvidence-based medicine should result in better standardisation of practice. This study aims to evaluate whether there remains variation in surgical techniques in native tissue and graft/mesh repairs of pelvic organ prolapse (POP) in UK practice. MethodsA questionnaire survey was conducted to describe current surgical tec...

Pelvic organ prolapse (POP) is a common presenting complaint in gynaecology. In the UK, prolapse accounts for 20% of women on the waiting list for major gynaecological surgery. It is therefore important that clinicians understand how to accurately assess women with prolapse. The aim of this article is to provide a comprehensive description of the a...

Background: The use of transvaginal mesh and biological graft material in prolapse surgery is controversial and has led to a number of enquiries into their safety and efficacy. Existing trials of these augmentations are individually too small to be conclusive. We aimed to compare the outcomes of prolapse repair involving either synthetic mesh inla...

Aims: To explore the role of sensory nerve impairment in women with pelvic organ prolapse, painful bladder syndrome, urinary and fecal incontinence, and sexual dysfunction. Methods: Medline and Embase were searched for articles in which sensory testing, either quantitative sensory testing or current perception thresholds, had been used to evalua...

The urinary tract, as with all other organ systems, undergoes numerous physiological adaptions in response to pregnancy. These normal adaptions can increase the risk of complications, such as acute infection and urinary retention, which in turn increase the risk of poor outcomes for the pregnancy. Other urogynaecological complications, for example...

Pelvic organ prolapse (POP) is a common presenting complaint in gynaecology. In the UK, prolapse accounts for 20% of women on the waiting list for major gynaecological surgery. It is therefore important that clinicians understand how to accurately assess women with prolapse. The aim of this article is to provide a comprehensive description of the a...

Extranodal non-Hodgkin's lymphoma (NHL) within the female genital tract is unusual, accounting for 1.5% of extranodal NHL, mostly in the ovaries. Primary NHLs of the uterus and cervix are rare, comprising only 0.54%–0.64% of all extranodal NHLs, most occurring in the cervix.1 Marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) of the...

Introduction and hypothesis: The objective of this study was to create a valid, reliable, and responsive sexual function measure in women with pelvic floor disorders (PFDs) for both sexually active (SA) and inactive (NSA) women. Methods: Expert review identified concept gaps and generated items evaluated with cognitive interviews. Women underwen...

Introduction: This paper provides a detailed discussion of the psychometric analysis and scoring of a revised measure of sexual function in women with pelvic floor disorders (PFD): the Pelvic Organ Prolapse Incontinence Sexual Questionnaire, IUGA-Revised (PISQ-IR). Methods: Standard tools for evaluating item distributions, relationships, and psy...

Background: Pelvic organ prolapse is common, with some degree of prolapse seen in up to 50% of parous women in a clinic setting, although many are asymptomatic. The use of pessaries (a passive mechanical device designed to support the vagina) to treat prolapse is very common, and up to 77% of clinicians use pessaries for the first line management...

Introduction and hypothesis: The objective of the study was to identify reasons why women declined participation in a pilot randomised controlled trial (RCT) comparing tension-free vaginal tape (TVT) under general anaesthetic (GA) with single incision sling (SIS) under local anaesthetic (LA). These data would inform the design of a larger trial to...

Bulkamid® is a periurethral bulking agent used to treat stress urinary incontinence (SUI). Manufacturers describe it as nontoxic, nonbiodegradable and biocompatible. Periurethral abscesses are one of the known complications of bulking agents. We present the first reported case of periurethral abscess following Bulkamid® injection. The woman had pre...

Pelvic organ prolapse (POP) is a common presenting complaint in gynaecology. It is therefore important that clinicians understand how to accurately assess women with prolapse. The aim of this article is to provide a comprehensive description of the assessment required. Anatomical assessment should be made using the standardized Pelvic Organ Prolaps...

The pathological cause of uterine prolapse is loss of integrity of the uterosacral and cardinal ligament complex and a weakening of the pelvic floor diaphragm. Uterine descent is a consequence rather than the cause of pelvic organ prolapse. However vaginal hysterectomy is an operation which is commonly performed to treat uterine prolapse. Does the...

Assessment of the 2-year outcome of anterior Prolift™ for women with recurrent anterior vaginal wall prolapse. This is a prospective study which was conducted in a tertiary unit in the North West of England and comprised 36 consecutive women with recurrent anterior vaginal wall prolapse. Women were assessed preoperatively and postoperatively at 6 m...

Assessment of the 2-year outcome of laparoscopic sacrocolpopexy. A prospective observational study of women undergoing laparoscopic sacrocolpopexy for prolapse. A tertiary referral unit in the North West of England. A total of 22 women taking part in a prospective longitudinal study of prolapse who had a laparoscopic sacrocolpopexy between Septembe...

The aim of this study is to provide long-term outcome data, at least 10 years, following laparoscopic colposuspension. The study includes a control group who underwent open colposuspension. A consecutive series of 139 women who had undergone laparoscopic colposuspension were reviewed and compared to 52 women who had an open colposuspension in the s...

The aim of this review is to present a summary of recently published research comparing laparoscopic and open colposuspension. It also examines the place of colposuspension in light of the continuing development other minimally invasive procedures for stress urinary incontinence. The results of two large multicentre randomised controlled trials wer...

Objective cure rates exceeding 75% are reported after colposuspension in women with stress incontinence, but extended follow-up has not been the rule. Small-scale studies also have been done to evaluate laparoscopic colposuspension after its introduction in 1991. A Cochrane review in the year 2000 yielded no conclusions about the long-term efficacy...

The aim of the study was to further validate three patient-based outcome measures (PBOM) used to assess the outcome of surgery for stress urinary incontinence and to compare their psychometric properties with a view to determining the most appropriate measure for clinical use. The work was embedded within a randomized controlled trial of laparoscop...

To compare the effectiveness and cost effectiveness of open and laparoscopic colposuspension in the treatment of stress urinary incontinence. A randomised controlled trial. Women were randomised between March 1999 and February 2002 and were seen for assessment at 6, 12 and 24 months, postoperatively. Women were recruited from six gynaecology units...