Fernando C. Wehrmeister

Fernando C. Wehrmeister
Universidade Federal de Pelotas | UFPEL · Department of Social Medical Studies

PhD

About

319
Publications
30,635
Reads
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3,906
Citations
Additional affiliations
January 2012 - present
Universidade Federal de Pelotas
Position
  • Professor (Associate)
January 2011 - December 2012
Universidade Federal de Pelotas
January 2010 - present
Federal University of Santa Catarina

Publications

Publications (319)
Article
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Background Environmental exposures in early life explain variability in many physiological and behavioural traits in adulthood. Recently, we showed that exposure to a composite marker of low maternal capital explained the clustering of adverse behavioural and physical traits in adult daughters in a Brazilian birth cohort. These associations were st...
Article
To evaluate the relationship between the grandmother's maternal pre‐pregnancy body mass index (BMI) (first generation—G1), the BMI of the female members of the birth cohort of Pelotas/RS, Brazil, 1993 (second generation—G2) and the children of the cohort members (third generation—G3). a longitudinal study using data from the 1993 Pelotas/RS cohort....
Article
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Background In the current Physical Activity Guidelines (PAG) for moderate- and vigorous-intensity physical activity (MVPA), abrupt transition from ≥ 60 min/day [youth PAG] to ≥ 150 min/week (≥ 22 min/day on average) [adult PAG] during emerging adulthood is poorly justified. The aim of this study was to examine body fat mass changes according to whe...
Article
Research to date on the impact of income throughout the life course on intelligence is inconclusive due to limited evidence. We set out to examine whether two models of life course family income (family income trajectories and low family income at birth) predicted a lower subsequent intelligence quotient (IQ). Data from two Brazilian birth cohorts...
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Purpose : The aim of this study was to systematically review the literature about the relationship between sleep duration and cognitive, academic and socioeconomic outcomes. Methods : We performed a systematic search in PubMed, Psyinfo, Scopus, Web of Science, ERIC, and Socindex up to June 2022, independently by two researchers. Original studies t...
Article
Background: Child maltreatment has been associated with substance use later in life, but few studies have used repeated measures. Objective: To assess the association between child maltreatment and use of psychoactive substances from adolescence to early adulthood, and whether this differs by sex. Participants and setting: 3641 participants fr...
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Background/Objectives Obesity has been reported as an attention-deficit hyperactivity disorder (ADHD) comorbidity. So far, few studies have aimed to explore the potential causal relationship between ADHD and obesity, as well as used other measures of body composition like fat-free mass (FFM) and fat mass (FM) as measures of obesity. This study aime...
Article
Background Our aim was to investigate the association between ultra-processed food (UPF) consumption and the incidence of elevated symptoms of common mental disorders (CMD) in two Brazilian birth cohorts. Methods We analyzed data from the 1993 (n = 3130) and 1982 (n = 3165) Pelotas Birth Cohorts. In the 1993 cohort, the 18y wave provided the first...
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Background Monitoring health inequalities is an important task for health research and policy, to uncover who is being left behind – and where – and to inform effective and equitable policies and programmes to tackle existing inequities. The choice of which measure to use to monitor and analyse health inequalities is thereby not trivial. This artic...
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Background: Trajectories of attention-deficit hyperactivity disorder (ADHD) traits spanning early childhood to mid-life have not been described in general populations across different geographical contexts. Population trajectories are crucial to better understanding typical developmental patterns. Methods: We combined repeated assessments of ADH...
Article
Background Inflammation-related proteins constitute a promising avenue in studying biological correlates of major depressive disorder (MDD). However, MDD is a heterogeneous condition – a crucial aspect to be considered in association studies. We examined whether inflammatory proteins are associated with categorical diagnosis, a dimensional total su...
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The objective of this study is to examine the association between preterm infants’ size at 1 year and attention-deficit/hyperactivity disorder (ADHD) assessed categorically and dimensionally in childhood and adolescence. We studied infants born < 37 weeks’ gestation from two Brazilian birth cohorts (n = 653). ADHD was evaluated using the Developmen...
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Maternal smoking during pregnancy causes several harmful effects, including deficits in the intelligence quotient (IQ), a measure associated with academic achievements and higher socioeconomic position. We aimed to measure the association between maternal smoking during pregnancy and offspring's IQ in two birth cohorts from Pelotas, Brazil. Data fr...
Article
Background Ideal cardiovascular health (ICH) promotes primordial prevention of cardiovascular diseases. However, whether ICH is associated with arterial stiffness in the transition to adulthood and the mechanisms associated has yet to be shown. The aim of this investigation was to: 1) investigate whether there is a prospective association between I...
Article
Background Early exposures such as maternal smoking can be associated mental disorders. We aimed to analyze the association between maternal smoking during pregnancy (MSDP), generalized anxiety disorder (GAD), and depression in the 1993 birth cohort (Pelotas, Brazil). Methods Data on maternal smoking were collected in the perinatal study, while in...
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Background Using data from Mexico, the country with the largest indigenous population in Latin America, we describe ethnic inequalities in coverage with women's health interventions at individual and municipal levels. Methods Cross-sectional study using data from the National Health and Nutrition Survey 2018 and the Mexican Intercensal Survey 2015...
Article
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Resumo: O objetivo foi estimar a prevalência do atraso nas três doses da vacina tetravalente (DTP+Hib) em crianças de 12 a 23 meses de idade, no Brasil, por meio dos dados da Pesquisa Nacional de Saúde (PNS) de 2013 e descrever o atraso em cada uma das doses segundo variáveis sociodemográficas, utilização de serviços e intervenções públicas de saúd...
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Objective: To estimate the prevalence of behavioral health risk factors and investigate clusters of simultaneous occurrences of these factors among students at a public university in Pelotas, state of Rio Grande do Sul, Brazil. Methods: This was a cross-sectional study among university students in the second semester of 2017. Physical inactivity...
Article
The co-occurrence of two or more diseases is called multimorbidity, and the occurrence of two or more risk factors is called simultaneity of risk factors. Multimorbidity and simultaneity of risk factors are not widely understood in adolescence and early adulthood. This paper aims to describe how multimorbidity and simultaneity of risk factors are d...
Article
Objective This study examined the association between WM and ADHD symptoms in young adults and whether IQ-score influenced this association. Method Data from the 1993 Pelotas (Brazil) Birth Cohort Study were analyzed ( N = 2,845). Working memory and ADHD symptoms were collected at 22 years. IQ was examined at age 18. Poisson regression with robust...
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This article aims to assess the relationship between an individual’s socioeconomic status over their life-course and their body mass index (BMI) at 22 years of age, according to the hypotheses generated by risk accumulation, critical period, and social mobility models. This was a population-based prospective study based on the Pelotas (Brazil) 1993...
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Background Fibrinogen is an important biomarker of inflammation, but findings from longitudinal studies that correlated fibrinogen with lung function in older adults are inconsistent. Aim To investigate the relationship between fibrinogen plasma levels and lung function impairment later in life. Methods Longitudinal analysis of 2,150 participants...
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Background Temporally-harmonized asset-based measures of wealth can be used to study the association of life-course wealth exposures in the same scale with health outcomes in low- and middle-income countries (LMICs). The within-individual longitudinal stability of asset-based indices of wealth in LMICs is poorly understood. Methods Using data from...
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Objective: To assess the frequency and severity of 24-hour respiratory symptoms according to COPD GOLD-ABCD classification (2017-version), the distribution of the patients with COPD into GOLD categories using mMRC (≥2) or CAT (≥10) scores, and agreement between these cut-off points. Methods: In this cross-sectional study (LASSYC study), 24-hour...
Article
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Background Inadequate antenatal care (ANC) has been associated with adverse pregnancy outcomes. ANC quality is considered a key component of the right to health and a route to equity and dignity for women and their children. Although ANC coverage is relatively high in Brazil, there are revealed some health disparities when coverage is examined by s...
Article
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Objective To investigate the influence of parental physical activity on offspring’s nutritional status in the 1993 Pelotas (Brazil) birth cohort. Design Birth cohort study. Setting The main outcomes were overweight and obesity status of children. The main exposure was parental physical activity over time, measured during the 11-, 15-, and 18-year...
Preprint
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Objective: The aims of this study were: 1) to estimate the prevalence of multimorbidity in 2013 and 2019 in adults aged 20–59 years; 2) to assess inequalities in the prevalence of multimorbidity in 2013 and 2019 according to educational level. Methods: Data from two cross-sectional surveys from the Brazilian National Health Survey in 2013 and 2019...
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This study aims to assess the association between mode of delivery and human capital among young adults enrolled in the 1982 and 1993 Pelotas birth cohorts, Rio Grande do Sul State, Brasil. In 1982 and 1993, the maternity hospitals of the municipality were daily visited, the births identified, and those live births, whose family lived in the urban...
Article
Background With the rise of vaccine hesitancy, which is allegedly more frequent among rich families, we hypothesized that the classical pattern of a positive gradient in coverage with rising wealth may no longer be observable in low- and middle-income countries (LMICs). Methods We analysed DHS and MICS surveys conducted from 2010-2018 in 88 LMICs....
Article
Background Wheezing may lead to asthma and reduced pulmonary function in later life. The study aims to identify wheezing trajectories and investigate their relation with pulmonary function and asthma-related outcomes at 22 years of age. Methods Individuals from a population-based cohort in Brazil (1993 Pelotas Birth Cohort) with post-bronchodilato...
Article
There is a high comorbidity between attention-deficit/hyperactivity disorder (ADHD) and asthma, and inflammation has been proposed as a potential pathophysiological mechanism behind this association. Most studies conducted so far have used a cross-sectional design, and none has evaluated the prevalence of asthma symptoms in patients with ADHD follo...
Article
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Resumo Imunizações de rotina durante pandemias podem ser prejudicadas. Este estudo estimou a cobertura vacinal para influenza em idosos durante a COVID-19 através do EPICOVID-19, inquérito populacional realizado em 133 cidades sentinelas dos 26 estados brasileiros e Distrito Federal. Selecionou-se 25 setores censitários por cidade, amostragem propo...
Article
Objective This study aimed to evaluate the relationship between sleep duration trajectories from adolescence to early adulthood and working memory, schooling and income at 22 years in the Pelotas 1993 Birth Cohort. Methods Sleep duration was self-reported at ages 11, 18 and 22. Sleep trajectories were identified using finite mixture. Schooling was...
Article
We investigated if cardiorespiratory fitness modifies the association between obesity and the level of physical activity. In this cross-sectional study, we analyzed data from 746 adults, free of diagnosed cardiorespiratory or locomotor diseases. We analyzed sociodemographic and clinical information, cardiovascular risk factors, cardiorespiratory fi...
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The objective of this article was to describe patterns of losses of information regarding accelerometer data and to assess the use of multiple imputation to generate physical activity estimates for individu-als without accelerometry data. Two birth cohort studies from Pelotas (Brazil) with participants aged 22 and 11-years old assessed objectively...
Article
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Reduced physical activity (PA) is an independent risk factor for lung function decline, hospitalization and mortality in chronic obstructive pulmonary disease (COPD) and affects a large proportion of patients from Europe and the United States. However, little is known of the level of PA of COPD patients in Latin America. The aim of this study was t...
Article
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Since the beginning of the pandemic of COVID-19, there has been a widespread assumption that most infected persons are asymptomatic. Using data from the recent wave of the EPICOVID19 study, a nationwide household-based survey including 133 cities from all states of Brazil, we estimated the proportion of people with and without antibodies for SARS-C...
Article
Objectives Neck and low back pains are the leading causes of years lived with disability, and using computers or mobile devices in excess could be risk factors for back pain. Our aim was to evaluate the association of the length of time using computers and mobile devices with neck, mid-back and low back pains and the number of regions with pain. S...
Article
Background : We aimed to examine the occurrence of major depressive disorder (MDD) in a population-based youth sample, assessing both categorical and dimensional presentations of the disorder and its clinical and sociodemographic correlates. Methods : We analyzed cross-sectional data from the latest assessment of the 1993 Pelotas Birth Cohort (n =...
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Our objective was to estimate the prevalence of excess weight and obesity, according to sex and income in the RPS Brazilian Birth Cohort Consortium (Ribeirão Preto, Pelotas, and São Luís). Participants in the Ribeirão Preto (1978/1979 and 1994), Pelotas (1982, 1993 and 2004) and São Luís (1997/1998) birth cohorts were included in different follow-u...
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Background Growth faltering has been associated with poor intellectual performance. The relative strengths of associations between growth in early and in later childhood remain underexplored. Objectives We examined the association between growth in childhood and adult human capital in 5 low- and middle-income countries (LMICs). Methods We analyze...
Article
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Purposes: The aims of this study were to investigate the cross-sectional and prospective associations between accelerometer-measured physical activity and cardiometabolic health in the transition to adulthood. Methods: Data from the 1993 Pelotas (Brazil) Birth Cohort were analysed (N=2,280). Moderate-to-vigorous intensity physical activity (MVPA...
Article
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Evidence suggests that maternal prepregnancy body mass index (BMI) is associated with offspring cardiometabolic risk factors. This study was aimed at assessing the association of maternal prepregnancy BMI with offspring cardiometabolic risk factors in adolescence and adulthood. We also evaluated whether offspring BMI was a mediator in this associat...
Article
Background Exposure to tobacco during pregnancy may disrupt fetal brain development and impact offspring cognitive development. Aims To perform a systematic review and meta-analysis on maternal smoking during pregnancy and intelligence quotient (IQ) in childhood, adolescence, and adulthood. Methods We searched PubMed, Lilacs, PsycINFO, and Web of...
Article
Objective This study investigated the association between screen time in adolescence and Attention Deficit Disorder (ADHD) at 22 years old. Method A sample of 2333 participants aged 11 years old without ADHD from the 1993 Pelotas Birth Cohort Study (Brazil) was followed up until the age of 22. Screen time variables included time spent in televisio...
Article
Little is known about the effects of excessive screen time on Working Memory (WM) in adolescents. The aim of this study was to investigate the association between measures of screen time in adolescence and Working Memory. Data from the 1993 Pelotas (Brazil) Birth Cohort Study were analyzed (N=3625). Self-reported screen time was collected at ages 1...
Article
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Background: Women's empowerment has a strong potential to promote sustainable development. We evaluate the association between women's empowerment and the Composite Coverage Index (CCI), a weighted average of coverage of eight interventions in reproductive, maternal, newborn and child health (RMNCH). We also assess whether these effects are modifi...
Preprint
Avaliou-se a cobertura vacinal para influenza em idosos na pandemia COVID-19 através do EPICOVID-19, inquérito de base populacional realizado em 133 cidades sentinela dos 26 estados brasileiros e Distrito Federal. Selecionou-se 25 setores censitários por cidade com amostragem proporcional ao tamanho, 10 domicílios por setor e uma pessoa por domicíl...
Article
Background : Ideal cardiovascular health (ICH) aims at primordial prevention of cardiovascular diseases in the population. However, there is a lack of research describing ICH in youth from middle-income countries. The aims of this study were to describe the prevalence of ICH at 18 and 22-years old and to investigate the influence of socioeconomic s...
Article
Background Gestational weight gain (GWG) has been associated with the accumulation of body fat in offspring, but little is known about the intergenerational relationship. Objective To assess the effect of GWG in grandmothers and mothers on the child's body mass index (BMI). Methods This is a sub‐study nested in the 1993 Pelotas (Brazil) Birth Coh...
Article
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This study aims to describe objectively measured physical activity (PA) in different periods of the day in young adults according to sex, socioeconomic position and during weekdays and weekends. This is a cross-sectional analysis carried out with the participants of the 1993 Pelotas Birth Cohort at 22 years. PA was assessed by triaxial acceleromete...
Article
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Objective We aimed at evaluating the association of maternal pre-pregnancy nutritional status with offspring anthropometry and body composition. We also evaluated whether these associations were modified by gender, diet and physical activity and mediated by birthweight. Design Birth cohort study. Setting Waist circumference was measured with an i...
Article
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Background and aims: Longitudinal cohort studies examining different generations can explain how health problems can be transmitted through genetic and environmental mechanisms and their effects on the health of offspring. This study aimed to present the design and to describe the characteristics of the baseline sample of a second generation cohor...
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Objective. To assess coverage and inequalities in maternal and child health interventions among Haitians, Haitian migrants in the Dominican Republic and Dominicans. Methods. Cross-sectional study using data from nationally representative surveys carried out in Haiti in 2012 and in the Dominican Republic in 2014. Nine indicators were compared: deman...
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Coverage of health interventions usually shows social gradients with higher levels among wealthy than among poor individuals. Owing to the upsurge of vaccine hesitancy in high income countries, the authors hypothesized that the social gradient may be changing over time also in the low- and middle-income countries and set out to test this hypothesis...
Article
Objectives To assess time trends in unplanned pregnancy, stratified by sociodemographic status, reproductive history, and inequalities in family income and women’s skin color, in Pelotas, Brazil.Methods Data from mothers of participants of the 1993 (N = 5264), 2004 (N = 4243), and 2015 (N = 4268) Pelotas birth cohorts were analyzed. Unplanned pregn...
Article
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Background: The role of diet in the etiology of asthma is still inconclusive. This paper evaluated the longitudinal association between diet quality and chest wheezing in young adults. Methods: This is a longitudinal study with follow-up information from 18- and 22-year-olds (18y and 22y) of the 1993 Pelotas (Brazil) Birth Cohort. Chest wheezing...
Article
Objective: We set forth to build a prediction model of individuals who would develop bipolar disorder (BD) using machine learning techniques in a large birth cohort. Methods: A total of 3,748 subjects were studied at birth, 11, 15, 18, at 22 years of age in acommunity birth cohort. We used the elastic net algorithm with 10-fold cross-validation...