Fernando Salazar-Anton

National Autonomous University of Nicaragua, León · Microbiology and Parasitology

Commercial antigens used to diagnose human neurocysticercosis are obtained from either a soluble parasite extract or a parasite-derived glycoprotein fraction. The aim of the present study was to identify antigenic proteins as potential diagnostic candidates in Mozambique. Soluble proteins from Taenia solium cysticerci were separated by two-dimensio...

Immunodiagnostic tests represent an important tool for diagnosis of cysticercosis, the disease caused by cysticerci of Taenia solium. Accurate diagnosis of neurocysticercosis (NCC) requires costly neuroimaging techniques (magnetic resonance imaging and computed tomography), which are seldom affordable for people in endemic countries. Hence, new low...

Commercial antigens used to diagnose human neurocysticercosis (NCC) are obtained from either a soluble parasite extract or a parasite-derived glycoprotein fraction. The aim of the present study was to identify antigenic proteins as potential diagnostic candidates in this context. Soluble immunogenic proteins from Taenia solium cysticerci were ident...

Sequences from 1650 unique ESTs in fasta format. (2.04 MB DOC)

Metabolic pathways and their mapped ESTs according to KEGG within the Blast2GO program. (2.00 MB PDF)

Result from Blast2GO web based annotation program. Results are presented as hits with a score <10−5. Results are divided into C = Cellular component, F = Molecular function and P = Biological process. (0.48 MB XLS)

Result from BLAST search with a score <10−5 of 1650 unique ESTs towards Taenia solium total ESTs at NCBI. (0.93 MB DOC)

Result from BLAST search with a score <10−5 of 154 unique ESTs predicted to contain a signal peptide. (0.05 MB DOC)

Result from KOBAS web based annotation program. Results are presented as hits with a score <10−5. Values in the column “Count and ratio” are divided into two rows per pathway. The top row corresponds to actual value. Bottom row corresponds to value in C. elegans for comparison. (0.48 MB DOC)

Result from BLAST search with a score <10−5 of 1650 unique ESTs. (0.66 MB DOC)

Neurocysticercosis is a disease caused by the oral ingestion of eggs from the human parasitic worm Taenia solium. Although drugs are available they are controversial because of the side effects and poor efficiency. An expressed sequence tag (EST) library is a method used to describe the gene expression profile and sequence of mRNA from a specific o...

Previous kDNA polymorphism-based reports have revealed the existence of two Trypanosoma rangeli genotypes (KP1+ and KP1-): SL and SSU rRNA gene polymorphism-based studies have revealed that five genotypes (A-E) are distributed throughout different Latin-American countries. Some evidence has shown that the genotypes' biogeographical distribution is...