Fernando Luiz Pereira Oliveira

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• PhD
• Professor at Federal University of Ouro Preto

Background Framingham risk score (FRS) is an important cardiovascular risk assessment tool, based on objective measurements of blood pressure and lipid profile, among other factors. However, in large population surveys, these measures are not always available, which limits their use. Objectives Evaluate the performance of the FRS predictive result...

Background Low plasma levels of 25-hydroxy-vitamin D (25(OH)D) are often observed in obese individuals, but the mechanisms linking vitamin D deficiency to adiposity remain unclear. This study evaluated whether cholecalciferol supplementation influences central adiposity by assessing changes in waist circumference (WC) and waist-to-height ratio (WHt...

Introdução: A maior ingestão de alimentos ultraprocessados (AUP) pode estar associada a um maior risco de obesidade. Objetivo: Nosso objetivo foi avaliar o consumo de AUP e sua associação com a ingestão de nutrientes e o excesso de adiposidade corporal em trabalhadores de turnos. Métodos: Um estudo transversal foi realizado em 2015 com 238 trabalha...

Detection of multivariate outliers is crucial in statistical studies. On the other hand, the statistical applications without identifying possible outliers may present incorrect results. This study proposes a new technique for detecting multivariate outliers based on cluster analysis. The method considers information inherent in the data itself. We...

Background: To investigate the relationship between shift work time, drowsiness events during driving, and the potential moderating effect of physical activity. Methods: A cross-sectional investigation involved 1413 male shift workers in an iron ore mining firm. Heavy machinery essential to the mining process was operated. A specific question from...

Objective: To evaluate the association between food consumption, by extent and purpose of processing, and cardiovascular disease (CVD) risk among rotating shift workers. Methods: The cross-sectional study included 213 male shift workers. Dietary intake was assessed using a 24-hour recall method conducted by trained interviewers. Food items were cla...

In this paper, we consider a Kirchhoff type problem with critical growth in RN. Using variational methods and the concentration-compactness principle, we demonstrate the existence and multiplicity of solutions.

Objective Estimate the incidence of the 30-year high cardiovascular risk and its determinants among graduates of federal universities in Minas Gerais. Methods This is a prospective cohort of 2,854 adults aged 20 to 59. The incidence of the outcome was calculated using the Framingham equation and its determinants were determined through multivariat...

Objective Estimate the incidence of the 30-year high cardiovascular risk and its determinants among graduates of federal universities in Minas Gerais. Methods This is a prospective cohort of 2,854 adults aged 20 to 59. The incidence of the outcome was calculated using the Framingham equation and its determinants were determined through multivariat...

Objective: This study aims to describe the health characteristics of rotating shift mining workers that may be related to a worse course scenario for COVID-19, according to literature data. Methods: Is a cross-sectional from three studies with 1478 shift workers. Social, demographic, clinical, and biochemical variables were analyzed. Risk factors f...

Objective To analyze the association between changes in body adiposity and length of service on a schedule of rotating shifts. Methods The study was a cross-sectional investigation conducted during the years 2012, 2015, and 2018, involving individuals engaged in rotating shifts at a company involved in iron ore extraction situated within the Iron...

In the well-known causative alternation, a verb appears either in a causative-transitive or in an inchoative-intransitive form. The inchoative form is marked with a reflexive clitic in some languages, such as Norwegian, but is unmarked in others, such as English. There are two main proposals to explain the alternation: a lexical-derivational accoun...

Objective To evaluate the BOAH (Body mass index, Observed apnea, Age, and Hypertension) and No-apnea score's diagnostic values for detecting obstructive sleep apnea (OSA) risk in shift workers. Methods Cross-sectional study with male rotating shift workers and drivers of heavy off-road machinery. The BOAH score is based on body mass index, witness...

We aimed to analyze the different trajectories of 30-year cardiovascular risk (CVR) and its independently associated factors in participants of the CUME Study, a prospective study with alumni from federal universities of Minas Gerais State, Brazil. In this study, 1,286 participants who answered the baseline (2016) and follow-up (2018 and 2020) ques...

Background Shift work is related to several negative impacts on the health of workers. This study aimed to evaluate the association between vitamin D deficiency (VDD) and hyperglycemia in shift workers. Methodology This cross-sectional study included male rotating shift workers in an iron ore extraction company. Participants were classified as VDD...

Statistical sequential analysis of binary data is an important tool in clinical trials such as placebo-controlled trials, where a total of K individuals are randomly allocated into two groups, one of size κ 1 receiving the treatment/drug, and the other of size κ 2 for placebo. The ratio z = κ 2 / κ 1 , namely “matching ratio,” determines the expect...

This study identified spatial clusters of type 2 diabetes mellitus among participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) residing in two cities and verified individual and neighborhood socioeconomic environmental characteristics associated with the spatial clusters. A cross-sectional study was conducted with 4,335 par...

Objective To evaluate the association between sleep parameters and hypovitaminosis D in rotating shift drivers. Material and Methods We conducted a cross-sectional study on 82 male rotating shift workers (24–57 years old) with at least one cardiovascular risk factor (such as hyperglycemia, dyslipidemia, abdominal obesity, physical inactivity, hyper...

The simulation of random correlation matrices is an important procedure in different research areas. This study presents a method called Custom Matrix generator, which generates correlation matrices that always fulfill the appropriate mathematical conditions. In addition, we present an algorithm based on this method which can generate customized co...

Aim: To assess the association of food consumption according to degree of processing with changes in systolic (SBP) and diastolic (DBP) blood pressure in adult participants of a Brazilian cohort. Methods: Longitudinal study with 2496 adult participants of the Cohort of Universities of Minas Gerais (CUME Project). Food consumption was categorized...

Objective: To explored the relationship between UPF consumption and dietary, lifestyle, and social determinants using pathway analysis in the baseline of the Cohort of Universities of Minas Gerais (CUME project). Design: Cross-sectional study, which path analysis was used to estimate direct and indirect effects of dietary practices, sleep, time...

Background Data on the validity of tools for sleep apnea risk detection in rotating shift workers are limited. The aim was to evaluate the Berlin questionnaire (BQ) and the Neck, Obesity, Snoring, Age, Sex (NoSAS) score for the detection of obstructive sleep apnea risk in shift workers. Methods This cross-sectional study included male rotating shi...

Background: This study identified spatial clusters of T2DM among participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) residing in two cities, and verified individual and neighborhood socioeconomic environmental characteristics associated with spatial clusters of T2DM. Methods: A cross-sectional study, conducted with 4,335...

Objectives The study aimed to evaluate the association between obstructive sleep apnea (OSA) and vitamin D deficiency (VDD) in shift workers. Methods This cross-sectional study included male rotating shift workers in an iron ore extraction company. Participants were classified as VDD when 25(OH)D < 20 ng/mL for a healthy population and 25(OH)D < 3...

A cross-sectional study enrolled participants from the CUME project (n = 289) who lived in Viçosa, Brazil. The neighborhood unit adopted was the buffer (200 meters), considering the participant’s residence as central point. We measure the number of public and private facilities inside the buffer as well as violent criminal occurrences. Food establi...

Background and aims: Higher intake of ultra-processed foods might be associated with an increased risk of obesity. Our objective was to evaluate the consumption of ultra-processed foods and their association with nutrient intake and excess body adiposity in shift workers. Design: Cross-sectional study conducted in 2016 with 238 male rotating shift...

Objectives The aim of the study is evaluate the association of obstructive sleep apnea syndrome (OSA) and vitamin D deficiency (VDD) in shift workers. Methods This cross-sectional study included rotating shift workers in an iron ore extraction company. Participants were classified as VDD when 25(OH)D < 20 ng/mL for a healthy population and 25(OH)D...

Background: The Food Frequency Questionnaire (FFQ) is usually used in epidemiological studies to assess food consumption. However, the FFQ must have good accuracy, requiring its validation and reproducibility for the target population. Thus, this study aimed to describe the construction of the online Food Frequency Questionnaire (oFFQ) used at the...

Objective Assess the reliability and validity of the self-reported diagnosis of depression of participants of the Cohort of Universities of Minas Gerais (CUME project). Methods This cross-sectional study included 79 participants who answered the project's follow-up questionnaire in 2018. A team of four psychiatrists applied the DSM-5, using the st...

Background and aims: Hypertension (HTN) is a chronic non-communicable disease influenced by non-modifiable risk factors, such as sex and age, as well as modifiable risk factors such as lifestyle, including diet and smoking. Moreover, diet quality among smokers is worse than that of non-smokers, mainly in terms of antioxidant content. Thus, the cur...

Shift work has serious health impacts due to desynchronization of the circadian rhythm; consequently, the workers have increased sleep disturbances. Another impact is working hours, which can contribute to decreased sun exposure and lead to the development of hypovitaminosis D. Vitamin D has been implicated in extraskeletal functions in many physio...

Objective: University professors are prone to show physical and psychological diseases related to excessive workload. Such overwork can affect the functioning of the autonomic nervous system, leading to a decrease in heart rate variability (HRV). HRV reflects the continuous fluctuation of the R-R intervals due to sympathetic and parasympathetic act...

In space state models for time series, a key point is the decision between modeling the trend of non-stationary processes through a deterministic or a stochastic term. The present paper introduces a Monte Carlo hypothesis test procedure to guide in such a decision. The method works for any time series distribution belonging to the location-scale fa...

This article presents a statistic to identify the proportional intensity of an area to belong to a space-time cluster, which is very important in spatial statistics. A significant extension of the so-called F-function has been described in detail, which, associated with new technology, allows the evaluation of the intensity of change moments in the...

Characterized by persistent fatigue, pain, cognitive impairment and sleep difficulties, Chronic Fatigue Syndrome (CFS) has been common in clinical practice. Studies indicate multiple factors contributing to CFS development: poor sleep, dehydration, psychological stress, hormonal dysfunction, nutrient deficiencies, among others. In risk work conditi...

Queues with general inter-arrival times in batches of random sizes, multi-servers, and finite-buffer spaces are studied, as the determination of their performance measures is a challenging inferential problem. This study focuses on estimating the important performance measures of GIX/M/c/N queues under finite samples. In Kendall notation, this abbr...

Background: In view of the costly methods currently available for the assessment of body adiposity, anthropometric obesity indicators have proven effective in predicting cardiovascular risk. Objective: To investigate the discriminatory power of body fat indicators for cardiovascular risk screening among shift workers. Methods: Cross-sectional study...

We evaluated the effect of physical training, stress, anthropometric measures, and gender upon the reactivity and recovery of the heart rate variability (HRV) during a cardiorespiratory test. Professors (N=54) were evaluated using the following: physical training: time, frequency, and length of physical exercise; resting heart rate (HR); maximum HR...

There are several situations in our daily lives in which queues are present, such as cafeterias, supermarkets, banks, gas stations, and so forth. The performance of such queues can be described by several measures. In this article, the focus is on estimates of traffic intensity (\(\rho\)), also called the utilization factor of the service station,...

Purpose The purpose of this paper is to investigate the effects of acai pulp consumption on biometric parameters and inflammatory biomarkers (sCD40L, CCL5, TNF-a and CRP) in apparently healthy women. Design/methodology/approach Nutritional intervention was performed with women who consumed 200 g of acai pulp daily during 30 consecutive days. First...

Demonstrar a prevalência da hipovitaminose D em trabalhadores de turno de uma empresa de mineração e verificar se, nesta população, há correlação entre as variáveis glicêmicas (hemoglobina glicada e glicemia de jejum) e os níveis séricos de vitamina D. Métodos: Estudo transversal observacional realizado por 2 anos consecutivos com trabalhadores de...

Objective: to verify the discriminatory power of adiposity indicators in the prediction of obstructive sleep apnoea (OSA) in shift workers. Methods: a cross-sectional study carried out in an iron ore extraction company, in Minas Gerais, Brazil. Anthropometric data were collected and polysomnography (PSG) was performed in 118 male shift workers who...

Objective: The present clinical study aims to describe protocol to evaluate the effects of vitamin D3 supplementation on the cardiovascular risk factors in a population of rotating shift workers. Design: A randomized, double-blind, placebo-controlled, parallel group clinical trial testing 2 oral dosages of cholecalciferol (14,000 IU and 28,000 I...

Resumo Objetivo: identificar a percepção dos trabalhadores de turnos alternantes de uma mineradora da região dos Inconfidentes, Minas Gerais, sobre sua qualidade de vida (QV) e analisar sua associação com indicadores de excesso de adiposidade corporal. Métodos: estudo transversal com 437 trabalhadores em turnos alternantes com um ou mais fatores de...

Folate, vitamin B6, and vitamin B12 intake can be important regulators for obesity development. Thus, we investigated the possible association between the intake of these vitamins and the excess body weight or obesity prevalence in the participants of the Cohort of Universities in Minas Gerais (CUME project). This study analyzed cross-sectional dat...

The joint buffer and server optimization problem (BCAP) is a non-linear optimization problem with integer decision variables that optimizes the numbers of buffers and servers such that the resulting throughput is greater than a pre-defined threshold throughput. This work presents a detailed review of the current literature that addresses allocation...

A identificação de outliers desempenha um papel importante na análise estatística, pois tais observações podem conter informações importantes em relação às hipóteses do estudo. Se modelos estatísticos clássicos são cegamente aplicados a dados contendo valores atípicos, os resultados podem ser enganosos e decisões equivocadas podem ser tomadas. Além...

Psychotria viridis is one of the species that produces N,N-dimethyltryptamine. Its decoction together with other species, such as Banisteriopsis caapi, produces ayahuasca, a beverage used for ritualistic and medicinal purposes. The goal of this study was to understand how environmental factors and cultivation methods influenced the content of N,N-d...

: This paper aims to study the efficiency of recombinant DNA insulin via models for accelerated life tests. The potency loss of these insulin products was evaluated periodically, subject to the conditions of temperature of 8°C, 25°C and 37°C. Insulin samples with potency at less than 100% were considered unfit for consumption, which characterizes t...

The aim of this study was to analyze the validity of self-reported diagnoses of metabolic syndrome (MetS) and its components through participants of the Cohort of Universities of Minas Gerais (CUME). A subsample of 172 cohort participants (33 males and 139 females, age 38 ± 11 years) was randomly selected for this study. The presence of MetS was de...

Abstract Background: The spatial scan statistic is widely used by public health professionals in the detection of spatial clusters in inhomogeneous point process. The most popular version of the spatial scan statistic uses a circular-shaped scanning window. Several other variants, using other parametric or non-parametric shapes, are also available....

Background The evidence that cardiovascular disease begins in childhood and adolescence, especially in the presence of excess weight, is associated with dysfunction on adipokine pro-inflammatory secretion. These affect glucose metabolism and lead to other complications related to insulin resistance and cardiovascular disease. This study assessed th...

In recent years Kulldorff’s circular scan statistic has become the most popular tool for detecting spatial clusters. However, window-imposed limitation may not be appropriate to detect the true cluster. To work around this problem we usually use complex tools that allow the detection of clusters with arbitrary format, but at the expense of an incre...

The lymnaeids are important in the epidemiology of Fasciola hepatica, a neglected and endemic zoonosis. The interaction between the internal defense system of Pseudosuccinea columella and F. hepatica has been little studied. In the present study the effect of infection by F. hepatica on P. columella circulating haemocytes was investigated. Changes...

A modification is proposed to the usual inference test of the Kulldorff’s spatial scan statistic, incorporating additional information about the size of the most likely cluster found. A new modified inference question is answered: what is the probability that the null hypothesis is rejected for the original observed cases map with a most likely clu...

This study aims to investigate L2-to-L1 cross-linguistic influence on bilinguals’ representation and processing with three psycholinguistics tasks. The interest in this type of effect lies in its possible association with cognitive control development. Our study focuses on possible influences of the non-dominant language on the dominant language: w...

Objetivo: Estimar a associação entre a alta exigência no trabalho e o elevado risco cardiovascular. Métodos: Estudo epidemiológico transversal, desenvolvido com 211 trabalhadores do campus saúde de uma universidade pública do Estado de Minas Gerais. A alta exigência no trabalho foi definida com base no modelo demanda-controle de Karasek, enquanto o...

Background: Clusters of cardiovascular risk (CVR) factors are associated with an increased risk of developing cardiovascular diseases (CVDs). This cross-sectional study assessed the associations between classic CVR factor clusters and inflammatory markers in Brazilian adolescents. Methods: Measurements included anthropometric, clinical and bioch...

Background The current concept of overweight/obesity is most likely related to a combination of increased caloric intake and decreased energy expenditure. Widespread inflammation, associated with both conditions, appears to contribute to the development of some obesity-related comorbidities. Interventions that directly or indirectly target individu...

Methods for the detection and inference of irregularly shaped geographic clusters with count data are important tools in disease surveillance and epidemiology. Recently, several methods were developed which combine Kulldorff’s Spatial Scan Statistic with some penalty function to control the excessive freedom of shape of spatial clusters. Different...

Este artigo tem o objetivo de comparar dois procedimentos utilizados para detecção do comprimento adequado de períodos de aquecimento (warm-up) em modelos de simulação para sistemas de filas. Os modelos de simulação para sistemas de filas visam reproduzir fluxos para sistemas de fila. Entretanto, ao obter estimativas para determinados parâmetros de...

The scan statistic is widely used in spatial cluster detection applications of inhomogeneous Poisson processes. The most popular variant of the spatial scan is the circular scan. However, such approach has several limitations, in particular, the circular window is not suitable to make the correct description of irregularly shaped and/or unconnected...

Fasciolosis, a parasitic disease caused by the trematode Fasciola hepatica underreported is expanding both in human and animal population, throughout the world. The constant use of synthetic drugs to treat this condition has led to the natural selection of resistant strains of the parasite. Hence, there is a growing focus on the potential anti-helm...

In practical applications of multivariate sliding window (SW) control charts, a considerable amount of difficulty lies in selecting parameters related to the window size and to the disposal of past observations. Although widely used for pattern recognition problems, to the best of the authors’ knowledge, there have been no comparative analyses of t...

This work is a simulation study to investigate the sensitivity of multivariate control charts for monitoring mean vectors in a bivariate Gaussian process with individual observations. The multivariate cumulative sum (MCUSUM), the multivariate exponentially weighted moving average (MEWMA) and Hotelling’s T charts are selected for analysis due to the...

Resumo Objetivo: Avaliar a associação entre variáveis sociodemográficas, clínicas e de utilização e a inadequação dos atendimentos realizados em uma Unidade de Pronto Atendimento (UPA). Métodos: Estudo transversal constituído por amostra de 791 atendimentos realizados na UPA de Ouro Preto em 2012. Avaliou-se o uso inadequado da UPA a partir da cons...

As filas de espera estão presentes em diversas situações do nosso dia a dia, tais como na lanchonete, no supermercado, no banco e no posto de gasolina. Várias são as medidas que descrevem o desempenho das filas. Neste trabalho daremos foco à estimativa da intensidade do tráfego rho (também denominado fator de utilização da estação de serviço), para...

In order to investigate the response of heart rate variability (HRV) components to postural change and their association with cardiovascular risk factors in shift workers, a cross-sectional study with 438 Brazilian males rotating shift workers was done. Anthropometric, body composition, and clinical measures were collected. Electrocardiogram was re...

We focus here on the use of kernels for the arrival process estimation of GI [X] /M/c/N queues, which in Kendal notation stands for independent general (GI) distributed bulk inter-arrival times of size X, Markovian (M) service times, c identical servers working in parallel, and a maximum capacity of N users simultaneously allowed in the systems, in...

Introduction: obesity, characterized by adiposity excess, is associated with endothelial dysfunction and possible inflammatory state with release of cytokines that determine endothelial function and can trigger chronic diseases. The dietary pattern are associated with the synthesis these cytokines. Fruits as the acai, which is rich in flavonoids,...

Nas últimas décadas, os métodos de reamostragem têm sido muito úteis, principalmente devido ao avanço da tecnologia computacional, na estimação de parâmetros para uma distribuição de interesse. Há diversas técnicas de reamostragem, dentre elas a técnica bootstrap. Neste trabalho, o bootstrap será utilizado para a construção de intervalos de confian...

To evaluate the association between lifetime exposure to shift work and blood pressure, fasting glucose (FG), anthropometric variables, body composition and heart rate variability (HRV). Male shift workers (N=438) were evaluated using principal component (PC) analysis. The variables used were: weight, body mass index (BMI), waist circumference (WC)...

This work presents a procedure for monitoring the centre of multivariate processes by optimizing the noncentrality parameter with respect to the maximum separability between the in- and out-of-control states. Similarly to the Principal Component Analysis, this procedure is a linear transformation but using a different criterion which maximises the...

Recently Knüsel (2008) proposed a new method of orthogonal rotation based on chi-square statistic, the Chisquaremax criterion. However, its performance has not yet been evaluated for the effect of outliers. Thus, we assessed the factorial model with Chisquaremax criterion for the effect of outliers using Monte Carlo simulation techniques in differe...

Introduction: In children, the presence of obesity is a major risk factor for the occurrence of cardiovascular diseases on the adulthood. Objective: To evaluate the association of anthropometry, body composition, clinical variables and biochemical profile with C-reactive protein and adiponectin levels, and insulin resistance in children in the muni...

O conceito de carta de controle, estabelecido por Shewhart nos anos 20, é uma poderosa ferramenta em controle estatístico de processo. Sua operação consiste na coleta periódica de itens produzidos, analisando-os de acordo com alguma característica de interesse. Há situações práticas que requerem o uso de cartas de controle para medidas individuais....

Os gráficos de controle de Shewhart para X_barra estão baseados na hipótese de que a distribuição da característica de qualidade é normal ou aproximadamente normal. Em muitas situações, entretanto, pode haver motivos para se duvidar da validade da hipótese de normalidade. Quando o gráfico não é robusto a erros de especificação do modelo, para estim...

RESUMO: Objetivando avaliar a distribuição espaço-temporal de hipertensão arterial e diabetes mellitus nos municípios de Minas Gerais, entre 2002 a 2012, aplicou-se as técnicas de análise espacial de dados de área, destacando-se a média móvel local, os coeficientes de autocorrelação global de Moran e o índice local de Moran. Além disso, foram const...

The present study investigates the acquisition of the English double object constructions (GOLDBERG, 1995) by Brazilian learners. We hypothesize that, due to first language (L1) influences, the prepositional ditransitive construction (John gave a book to Mary) will be acquired earlier, while the ditransitive construction (John gave Mary a book) wil...