Fernando Facio- MD , PhD.
- Professor (Assistant) at School of Medicine of São José do Rio Preto
Fernando Facio
- MD , PhD.
- Professor (Assistant) at School of Medicine of São José do Rio Preto
President Of Latin American Society for Sexual Medicine - SLAMS
Vice-Chair Publication Committee ISSM
Co-Chair ICSM2024
About
168
Publications
90,981
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421
Citations
Introduction
Graduated in Medicine from the School of Medicine of São José do Rio Preto - FAMERP and doctorate in Health Sciences, postdoctoral fellow at Johns Hopkins Hospital -USA. Currently, he is Adjunct Professor of Medical and Post-Graduation courses, Coordinator of the Research Group on Sexual Medicine. Member of internantional societies: SBU, AUA and ISSM - Education Committee.
Current institution
School of Medicine of São José do Rio Preto
Current position
- Professor (Assistant)
Additional affiliations
July 2008 - December 2009
February 1992 - present
August 2008 - December 2009
Publications
Publications (168)
Peyronie's disease (PD) is characterized by the formation of fibrotic plaques within the penile connective tissue, leading to abnormal curvature, pain, and erectile dysfunction, profoundly affecting patients' physical and psychological well-being. The Peyronie's Disease Questionnaire (PDQ) is a validated instrument designed to assess key aspects of...
Peyronie's disease (PD) is a progressive fibrotic disorder affecting the tunica albuginea (TA) of the penis. MMF was evaluated previously after experimental induction of PD. We investigate the modulation of metalloprotease (MMP) expression and collagen deposition in the TA in PD induced after treatment with MMF in rats. Rats were divided into: cont...
Spontaneous steinstrasse (“stone street”) is a collection of stones within the ureter and is a rare and understudied event. Factors such as infection, altered kidney function, and degree of obstruction are used to define the most adequate therapeutic option. Treatment can be either conservative or surgical. The decision of which depends on the clin...
Kidney transplant is the established treatment for patients with chronic kidney disease but is associated with complications due to the complexity of the procedure. Calyceal fistulas are rare urological complications in transplants caused by arterial occlusion with segmental infarction of the graft. Treatment is based on the extension of the affect...
Background:
Implantation of the double-J stent is a common procedure in urology. The function of this device is to maintain the flow of urine from the ureteropelvic junction to the urinary bladder when the ureter is blocked or partially blocked for some reason. Once in place, the stent may cause low back pain, hematuria, symptoms of urinary irrita...
A transexualidade, tema de grande interesse social e de indiscutível atualidade, abrange aspectos médicos, psicológicos e jurídicos, pois não se considera mais o sexo apenas como elemento fisiológico, geneticamente determinado e imutável. Contudo, ganhou novos contornos e voltou à tona diante de práticas mostradas na mídia. A transexualidade diz re...
Background:
The coronavirus disease 2019 (COVID-19) appeared in China and spread quickly to other regions of the country and around the world, changing the way of life of individuals and the routine of healthcare systems.
Objective:
The aim of the present study was to investigate the impact of the pandemic on the surgical treatment of patients w...
Introduction:
The 2019 coronavirus (COVID-19) rapidly spread throughout the world, with diverse negative consequences in all fields, including the continuity of treatment for patients with other diseases. The public hospital for high-complexity procedures affiliated with the São José do Rio Preto School of Medicine, São Paulo, Brazil, normally has...
Introduction: Sexuality is a central aspect of being human, though its diversity is not completely accepted in society nor at medical schools. As a consequence, minority medical students face discrimination, poorer mental health, loneliness and worse academic performance. Objective: To investigate the sexual diversity of medical students and its po...
Perineuriomas are benign, rare neoplasms of the nerve sheath, basically in two forms: intraneural and extraneural. Extraneural forms are mainly found in the trunk and limbs, while visceral organs are rarely affected. To date, there have been no previous reports in the literature of bladder perineurioma. In this case, we report a young adult with he...
Introduction
Peyronie´s disease(PD) is a common disease among men which causes tortuosity in the penis, making it difficult and sometimes even preventing sexual activity. PD corresponds to the presence of fibrotic disorder in the tunica albuginea of the corpus cavernosum.This disorder is characterized by excessive accumulation of collagen fibers an...
Condyloma acuminatum is a common clinical outcome of human papillomavirus (HPV) in men. A prospective investigation was performed of the clinical and molecular profile of 122 patients with condyloma acuminatum treated by the Brazilian public healthcare system. The patients were evaluated clinically. The fragments were submitted to molecular analysi...
Abstract
Background
The rapid dissemination of the coronavirus 2019 (COVID-19) had dramatic effects on individuals and healthcare systems in 2020. At our tertiary hospital, surgeries were recommended for patients at high oncological risk, with the prioritization of the maintenance of care and treatment of cancer. We aimed to assess the impact of th...
Hibernomas are rare lipomatous tumors derived from brown adipose tissue. Only two cases of hibernomas in the scrotum have been reported in the literature so far. Brown adipose tissue is responsible for thermogenesis in hibernating mammals and embryos. In adult humans, reminiscent brown tissue is most frequently located in the axial skeleton, scapul...
Introduction: Respiratory disease (COVID-19) caused by the new coronavirus (SARSCoV-2) has spread around the world causing respiratory illnesses and deaths. The COVID-19 pandemic caused an unprecedented crisis in the field of education. It is essential to reflect on the role of educational systems in curricular training, especially for doctors. Obj...
Solitary fibrous tumor (SFT) of the pleura is a rare tumor of an unknown cause and corresponds to 5% of all pleural tumors. It is generally asymptomatic and discovered incidentally through imaging exams. The definitive diagnosis is based on histopathological findings and treatment is surgical. This paper describes the case of a previously healthy f...
Abdominoscrotal hydrocele is an uncommon condition characterized by an hourglass-shaped scrotal hydrocele with an intra-abdominal component connected by an isthmus within the inguinal canal. We report a rare case of an adult patient with giant abdominoscrotal hydrocele. Despite recent trends toward less invasive treatments, in this case, the surgic...
Introduction
Sexuality is a multifaceted and makes up part of the lives of all individuals.
Aim
To evaluate the teaching of sexual health to students in the basic cycle of an undergraduate course in medicine.
Methods
A descriptive, cross-sectional study was conducted using primary data on the teaching of sexual health in the first 4 years of the...
Objective:
Metabolic changes caused by anxiety can interfere in both the surgery itself and the recovery process. One way to reassure the patient is to clarify how the procedure will be performed and discuss the possible complications. This study aimed to investigate the anxiety level of candidates for radical prostatectomy at a university hospita...
This study aimed to characterize patients with erectile dysfunction (ED) evaluated by the psychologist who participates in the Urology team of a teaching hospital. The following data from medical records of patients treated between January / 2011 and April / 2015 were analyzed: 1) the urologist's referral, with diagnosis and the reason for the requ...
Besides these complications amidst the pandemic, low levels of testosterone in men older than 60 years of age can further aggravate the lack of libido and low energy, generating profound suffering due to the negative impact on sexual behavior. Thus, specialized, multidisciplinary care is needed, with online medical appointments aimed at the continu...
The placement of a suburethral sling is standard treatment for stress urinary incontinence. The transobturator technique (TOT) emerged as an alternative to minimize the risks of the blind insertion of needles, leading to a lower rate of perforation complications compared with the retropubic approach. We present a case of injury to a branch of the l...
Abstract: Lymphedema is a specific type of edema stemming from a failure in the formation or drainage
of lymph. This condition can be congenital or acquired. The clinical treatment of genital lymphedema
involves compression mechanisms of the penis. In acquired cases, the individual is born with the lymphatic
system intact, but this system is damage...
Ureteritis cystica is a rare urological disease with an undefined etiology. Despite the benign behavior, the differential diagnosis should be investigated, as other conditions the cause filling defects in the ureters may occur. We present a rare case of a patient with ureteritis cystica whose differential diagnosis was satisfactory.
With the pandemic and schools closed for weeks
or more, adolescents are no longer under the watchful
eyes of their teachers, community, and family due to a
forced change of priorities. In this scenario, exposure
to the sexual content freely available on the internet
and in videogames contributes to the early development of beliefs and sexual attitu...
Cancer de prostata(CaP) e a neoplasia mais diagnosticada em homem apos o cancer de pele, com cerca de 161.000 novos casos a cada ano. Ao mesmo tempo, a conduta baseada em vigilância ativa aumentou na ultima década, com taxas de vigilancia citadas em 64% em algumas praticas urologia.
Background: Sexuality occupies a fundamental position in the lives of individuals and is related to general health. However, undergraduate curricula in medical courses address this topic in an incomplete manner. The aim of this study is to investigate sexual health education among undergraduate medical students.
Methods: A descriptive, cross-sectio...
The aim of the present study was to evaluate the histological, histochemical, and stereological changes caused by mycophenolate mofetil (MMF) on the tunica albuginea of rat penises submitted to an injection of transforming growth factor beta (TGF-β) for the induction of Peyronie’s disease (PD). Twenty adult male Wistar rats were divided into four g...
Erectile dysfunction (ED) affects 18 million men in the United States alone. Its prevalence is 52% among men aged from 40 to 70 years and 70% among those older than This condition may be related to changes in penile blood flow since the etiology is
vascular in 60% of patients.Cardiovascular disease (CVD) and ED share the
same risk factors, such as...
Cake kidney is a rare abnormality of the urinary tract. It is generally asymptomatic but can lead to renal and nonspecific systemic manifestations. This report describes a case of cake kidney drained through a single ureter diagnosed in a female patient with recurring urinary infection.
Obesity is a modern disease that may be associated with sexual dysfunction, the inability to participate in a pleasurable sexual relationship. Sexual dysfunction is more common in women than men. The objective of this study was to investigate risk factors for sexual dysfunction in obese women. Articles in English and Portuguese published between 19...
Obesity is a modern disease that may be associated with sexual dysfunction, the inability to participate in a pleasurable sexual relationship. Sexual dysfunction is more common in women than men. The objective of this study was to investigate risk factors for sexual dysfunction in obese women. Articles in English and Portuguese published between 19...
Paratesticular tumors account for 5% of tumors originating in the scrotum. Angiomyofibroblastoma-like tumor is a rare benign mesenchymal soft tissue tumor found in the genital region in both sexes and is even rarer in the spermatic cord. The origin of this tumor remains the object of speculation, but it is believed to originate from perivascular me...
Varicocele is a dilation of the pampiniform venous plexus, mainly affecting the left side of the scrotum. In rare cases, however, the right side is affected. When this occurs, a retroperitoneal disease should be suspected , such as right-sided renal neoplasm. The present case report highlights the importance of right-sided varicocele in the diagnos...
Xanthogranulomatous orchitis is a non-neoplastic inflammatory condition characterized by the destruction of testicular tissue with macrophage infiltrate (1). Xanthogranulomatous masses is often found in the kidneys and gallbladder, with few cases of occurrence in the testicle and spermatic cord (2,3). We report a case of xanthogranulomatous orchiti...
Xanthogranulomatous orchitis is a rare, non-neoplastic inflammatory condition. We present
a case of a 55-year-old diabetic male with an increase in volume, pain and edema in right testicle with a
one-year history. The examination involved the investigation of inflammatory markers and ultrasound.
Exploration of the scrotum revealed important destruc...
Abstract: Xanthogranulomatous orchitis is a rare, non-neoplastic inflammatory condition. We present a case of a 55-year-old diabetic male with an increase in volume, pain and edema in right testicle with a one-year history. The examination involved the investigation of inflammatory markers and ultrasound. Exploration of the scrotum revealed importa...
Abstract: Introduction: Erectile dysfunction (ED) is the most common cause of sexual dysfunction in men and
shares several risk factors with systemic conditions, such as cardiovascular disease and metabolic syndrome (MetS).
Objective: Investigate the relationship between ED and MetS among patients at a university hospital. Patients and
Methods: Pat...
Retrocaval or circuncaval ureters are rare congenital anomaly, in which the ureter is located posterior to the inferior vena cava (IVC). Usually, patients present symptoms in the 3rd or 4th decade of life due to compression of the ureter by the IVC, with obstruction of the urinary flow and consequent hydronephrosis. Herein we report the case of a 6...
Most medical students are interested in education about
sexual medicine in the practice and they believe that sexual
medicine should be included in medical school curricula (1).
Due to the growing need for medical care for problems
related to human sexuality, it has been recommended that
sexual medicine can be considered in medical courses
Introduction: Peyronie’s disease (PD) is defined as an acquired fibrosis of the tunica
albuginea, which can result in pain, deformity and erectile dysfunction. Currently, PD
treatment is controversial because oral therapies present limited efficacy.
To investigate the antifibrotic effect of mycophenolate mofetil (MMF) in experimental
model of PD i...
Intratunical injection of TGF-β promoted fibrotic alterations in the region of penile tunica albuginea in Wistar rat, corresponding to PD
In this model of induction of PD, MMF acts as a regenerating antifibrotic agent
Peyronie’s disease (PD) is defined as an acquired fibrosis of the tunica albuginea, which can result in pain, deformity and erectile dysfunction. Currently, PD treatment is controversial because oral therapies present limited efficacy. To investigate the antifibrotic effect of mycophenolate mofetil (MMF) in experimental model of PD using morphologi...
Inguinal hernias are a common disease in adults, but involvement of extraperitoneal structures is rare. This condition is usually asymptomatic and an incidental finding during the surgical correction of inguinal hernias, often resulting in iatrogenic damage. We present a rare case of left renal agenesis and right inguinal hernia, with the ureter be...
Inguinal hernias are a common disease in adults, but involvement of extraperitoneal structures
is rare. This condition is usually asymptomatic and an incidental finding during the surgical correction of
inguinal hernias, often resulting in iatrogenic damage. We present a rare case of left renal agenesis and right
inguinal hernia, with the ureter be...
There are several risk factors associated with erectile dysfunction (ED) and so it is important to identify them to improve the therapeutic approach. The objective of this study was to evaluate the association between obesity and ED. In this prospective cross-sectional observational study, the IIEF questionnaire was used to evaluate erectile functi...
BACKGROUND: Ureteral catheters are commonly used by different medical specialties more often in medical centers that have a considerable flow of patients making monitoring difficult. Furthermore, forgotten catheters can cause serious complications increasing hospital costs and the possibility of litigation. This study evaluated a Google Drive-hoste...
BACKGROUND: Ureteral catheters are commonly used by different medical specialties more often in medical centers that have a considerable flow of patients making monitoring difficult. Furthermore, forgotten catheters can cause serious complications increasing hospital costs and the possibility of litigation. This study evaluated a Google Drive-hoste...
Introduction:
This paper presents a rare event of genital self-mutilation and few cases are reported in the literature.
Case description:
We report on a patient who performed partial self-penectomy 18 months after bilateral testicular amputation, as a form of self-mutilation.
Conclusions:
The main hypotheses to explain the recurrence of self-m...
BACKGROUND: Ureteral catheters are commonly used by different medical specialties more often in medical centers that have a considerable flow of patients making monitoring difficult. Furthermore, forgotten catheters can cause serious complications increasing hospital costs and the possibility of litigation. This study evaluated a Google Drive-hoste...
Background: Over the last decade, male sexual dysfunction has become a topic of great interest to clinicians, researchers and to public health managers. Many chronic coronary artery disease patients in Brazil suffer from erectile dysfunction (ED) and most do not feel comfortable about reporting their complaints. One of the main protection mechanism...
The aim of this study was to identify strategies to transfer responsibility of the maintenance of the results of lymphedema
treatment to the patient. Methods. Maintenance of the reduction of edema was evaluated in a prospective clinical trial in patients
with Stage II leg lymphedema. Twenty-one lymphedematous lower limbs were evaluated in Cl´ınica...
Background
New surgical techniques for nephrectomy mainly related to early diagnosis made possible by advances in imaging studies have been developed in recent decades. However, postoperative renal dysfunction is a constant concern because of the major problems faced by healthcare services and by the patients themselves. To assess risk factors for...
The teaching policy is that educational institutions should encourage and facilitate research, contributing to the preparation of select minds, familiar with scientific thinking and method, giving professionals of the future the ability to think independently and critically.Hence, in the pursuit of perfection and medical-professional qualification,...
This paper presents the first case of a kidney graft recipient with double malignancy of the upper urinary system and cancer of the urethra evident four years after transplantation.
Genital lymphedema in men can affect the penis and/or scrotum, causing deformity and causing sexual limitations, social isolation, poor quality of life and recurrent subcutaneous infections due to difficulties in hygiene. There are few studies in the literature emphasizing the treatment of penile fibrosis after penoscrotal lymphedema. The purpose o...
Genital lymphedema in men can affect the penis and/or scrotum, causing deformity and causing sexual
limitations, social isolation, poor quality of life and recurrent subcutaneous infections due to difficulties
in hygiene. There are few studies in the literature emphasizing the treatment of penile fibrosis after
penoscrotal lymphedema. The purpose o...
Dengue fever is the most prevalent viral disease caused by arthropods
in the world. Post-dengue neurological complications have been
reported in less than 1% of cases. Urinary and sexual dysfunctions
after complications of dengue infection are rare. We report a case of
a young patient who presented with transverse myelitis after dengue
infection an...
Abstract
Background: Risk factors may influence the improvement or worsening of erectile dysfunction (ED). The aim of the current study was to evaluate the effect of systemic hypertension on ED in patients with peripheral arterial disease.
Methods: The effect of hypertension on ED was assessed in 125 consecutive patients in a cross-sectional quanti...
Renal infarction is an uncommon cause of acute abdomen thus the clinical diagnosis is difficult. With the advent of endovascular procedures, nephrectomy is increasingly less used as a treatment for kidney infarction. In this report, we present a patient with renal infarction who was submitted to surgery.
Renal infarction is an uncommon cause of acute abdomen thus the clinical diagnosis is difficult. With the advent of endovascular procedures, nephrectomy is increasingly less used as a treatment for kidney infarction. In this report, we present a patient with renal infarction who was submitted to surgery.
Little is known about the factors that influence the graduation of medical students in relation to the preparation of their approach to sexual health care. Teaching hours for sexual education in undergraduate medical courses are frequently insufficient to prepare them for their roles to treat this complex issue. This study aimed to evaluate the del...
Poster presented in world meeting in sexual medicine
Objective: The purpose of this study was to investigate education activities more indicated about teaching sexual medicine for medical students. Material and Methods: A one-day course was organized to tackle the main concerns of patients in respect to sexual health problems. The course was comprised of classes and time for students to discuss doubt...
Objective: The purpose of this study was to investigate education activities more indicated about teaching sexual medicine for medical students. Material and Methods: A one-day course was organized to tackle the main concerns of patients in respect to sexual health problems. The course was comprised of classes and time for students to discuss doubt...
The aim of this study was to investigate the effect of the anti-inflammatory and anti-fibrotic actions of ANX1 on erectile function(EF). Forty-eight male Wistar rats were randomly distributed into four equal groups: one group (sham operation—control) and three groups (bilateral cavernous nerve (CN) crush injury). Crush injury groups were treated pr...
Questions
Questions (4)
The mechanisms for how LiSWT improves erectile dysfunction appear to be promising and some initial studies have demostrated benefit.
But At the time, the use LiSWT , PRP and Stem cell should be considered experimental until appropriate RCTs have demostrated proven efficacy and safety.
Male population upper 60s died more with Covid-19 in China and Italy (69-80%) compared with female.
social isolation increases difficultes to appointment to maintain TRT
The effects of testosterone replacement on metabolic and inflammatory markers in this setting have not been evaluated. This is important as opiate use itself has been associated with metabolic abnormalities. Could the TRT determine the improvement effects of testosterone administration on metabolic and inflammatory markers in adult men with opioid-induced androgen deficiency?
The first thing to understand about testosterone replacement is that oral testosterone (pills taken by mouth) doesn’t really work because it is broken down so quickly by the liver. The solution to this problem involves patches, gels and shots. Here are some options for treat patients.
