Fernando Yamamoto Chiba

São Paulo State University | Unesp · Araçatuba Dental School

The objective was to analyze the social determinants of health in Angola. This is a documentary, exploratory and quantitative research, carried out with data from the 2015-2016 Multiple Indicators and Health Survey in Angola. The analyzed variables were: access to drinking water sources; appropriate sanitary facilities; access to electricity; educa...

Background: Drug addiction can harm oral health, as the use of illicit substances can reduce salivary flow and the buffering capacity of saliva, facilitating the development of periodontal disease. Salivary cortisol levels can influence oral health, as increased levels of this hormone may be related to a decreased immune response, affecting periodo...

O objetivo foi valiar o impacto causado pela vacinação com o início da campanha de imunização em relação aos dados epidemiológicos da Covid-19 nos Distritos Sanitários Especiais Indígenas(DSEIs) de Mato Grosso em 2021 . Trata-se de um estudo ecológico, documental, quantitativo, realizado de Janeiro a Julho de 2021. Foi efetuada uma análise document...

Considerando a relevância da padronização, organização, racionalização e ergonomia para o sucesso nas ações realizadas no atendimento odontológico e prevenção de doenças ocupacionais, o objetivo do presente trabalho foi analisar a eficácia da implementação da filosofia Lean Healthcare em uma clínica de ensino da Faculdade de Odontologia de Araçatub...

Avaliar fatores associados à qualidade de vida relacionada à saúde bucal dos pacientes com Transtorno do Espectro Autista (TEA). Trata-se de um estudo observacional transversal, de abordagem quantitativa, no ano de 2023. Os dados foram coletados por meio do instrumento de pesquisa estruturado sobre qualidade de vida de crianças com TEA e seu estado...

Editorial Nos dias 3 a 5 de agosto de 2023 foi realizado, com muito sucesso, o “VII Workshop de Pós-graduação em Saúde Coletiva em Odontologia e V Encontro de Odontologia em Saúde Coletiva e Bioética”, na Unesp - Faculdade de Odontologia de Araçatuba - FOA. Nesta sétima edição do evento foram comemorados os 30 anos do Programa de Pós-Graduação em S...

Objective: This study aimed to evaluate the influence of high-fat diet (HFD) and melatonin (MEL) treatment on the progression of inflammation and alveolar bone resorption (ABR) in rats with AP. Design: Forty male Wistar rats were divided into four groups: apical periodontitis (AP), HFDAP, APMEL and HFDAPMEL. The animals were fed an HFD or standa...

Objective: The objective was to carry out a systematic review on the acceptance of parents to vaccinate their children against COVID-19 and the factors that contribute for vaccination hesitancy. Methods: The Preferred Reporting Items for Systematic Re- views and Meta-Analyses (PRISMA) guidelines and the Patient, Intervention, Comparison and Outc...

Objetivo: Investigar os níveis de depressão e estresse e a relação entre essas variáveis com a concentração de cortisol salivar, um biomarcador de estresse, em mulheres vítimas de violência. Metodologia: Trata-se de um estudo transversal, quantitativo, descritivo e associativo realizado no ano de 2018, com 146 mulheres, residentes em um município d...

Os transtornos alimentares são caracterizados como distúrbios biopsicossociais nos quais o indivíduo pode apresentar graves complicações físicas e psicológicas. O objetivo neste estudo foi avaliar os níveis de depressão, ansiedade, estresse e qualidade do sono em pacientes com anorexia ou bulimia nervosa. A amostra foi composta por 30 mulheres em a...

To evaluate the effects of melatonin (MEL) on the expression of toll-like receptor-4 (TLR4); myeloid differentiation primary response protein-88 (MyD88); TIR-domain-containing adapter-inducing interferon-β (TRIF); IFN regulatory-factor-3 (IRF-3); nuclear factor kappa-B (NF-κB); plasma concentrations of interleukin-1β (IL-1β) and lipopolysaccharide...

Objetivou-se analisar as atividades profissionais de egressos do Programa de Pós-Graduação Saúde Coletiva em Odontologia da Universidade Estadual Paulista (UNESP), Campus de Araçatuba. Trata-se de uma pesquisa descritiva, na qual avaliou-se, por meio de consulta aos dados disponibilizados na Plataforma Lattes, informações curriculares de 99 egresso...

Aim: To analyse the effects of melatonin (ME) treatment on oxidative stress and insulin resistance (IR) in rats with apical periodontitis (AP) fed a high-fat diet (HFD). Methodology: Eighty 60-day-old rats were divided into eight groups: control (CN), AP, HFD with AP (HFDAP), control with ME (CNME), AP with ME (APME), HFD with ME (HFDME) and HFD...

Background: Maternal periodontal disease (PED) and apical periodontitis (AP) are associated insulin resistance (IR), increased tumor necrosis factor-α (TNF-α) levels, and alterations in insulin signaling (IS) in the gastrocnemius muscle (GM) of adult offspring. TNF-α stimulates I kappa B kinase (IKK) and c-Jun N-terminal protein kinase (JNK), resu...

(1) Background: This study evaluates the effects of photobiomodulation (PBM) therapy on the peri-implant bone healing of implants with a machined surface (MS) and treated surface (TS). (2) Methods: Topographic characterization of the surfaces (scanning electron microscopy [SEM]-energy dispersive X-ray spectroscopy [EDX]) was performed before and af...

Objective: To evaluate the prevalence and severity of malocclusion and its impact on oral health-related quality of life (OHRQoL) and self-reported satisfaction of patients with anorexia and bulimia nervosa. Methods: The sample consisted of sixty women who attended a specialized mental health clinic of a Brazilian medical school. Participants we...

Objetivo: Revisar sistematicamente as evidências existentes sobre a prevalência da necessidade de tratamento ortodôntico em jovens de 12 a 15 anos de idade.Métodos: Realizou-se uma busca eletrônica nas bases de dados Portal Regional da BVS, PubMed, Scielo, Cochrane, Web of Science, Embase e Scopus utilizando descritores e termos utilizados nas publ...

Interrupções nos ritmos hormonais, sono, padrões alimentares e exposição à luz ocorrem durante o trabalho em turnos. O sono é afetado pelo trabalho em turnos, em parte devido à incapacidade de mudar o ritmo circadiano do sono para corresponder ao horário de trabalho. Mudanças no estilo de vida que causam distúrbios no ritmo circadiano podem ter uma...

Avaliar a adesão à profilaxia pré-exposição (PrEP) ao HIV após 3 anos de implantação no Sistema Único de Saúde (SUS). Estudo ecológico, quantitativo, realizado no ano de 2021, no Brasil. Foram coletados dados a respeito da PrEP HIV, no painel de monitoramento disponibilizado pelo Ministério da Saúde – Governo Federal. As variáveis estudadas foram t...

Purpose: To analyse the epidemiological profile of dental caries in children aged 5 and 12 years in the city of Benguela, Angola. Materials and methods: This was an observational, analytical, cross-sectional study conducted in 2019 with 190 12-year-old schoolchildren and 240 5-year-old schoolchildren from the public education system in Benguela,...

Objetivo: Investigar a prevalência, severidade e necessidade de tratamento das maloclusões e seu impacto na qualidade de vida relacionada à saúde bucal (QVRSB) em adolescentes de 12 anos.Materiais e métodos: Estudo transversal realizado com 453 adolescentes. A maloclusão foi avaliada pelo Índice de Estética Dentária (DAI) e o Questionário de Percep...

Introdução: No Brasil, presencia-se e convive-se com várias formas de violência contra a mulher, constituindo-se em um problema social refletido em todas as camadas da sociedade. Entre os diversos tipos de agressões infligidas contra a mulher, as de natureza física, que atingem a região da cabeça e pescoço, apresentam alta prevalência. Objetivo: Re...

Aims To investigate the effect of resistance training-RT on glycemia, expression of the glucose transporter-GLUT4, bone mineral density-BMD, and microstructural and biomechanical properties of osteopenic rat bones in neonatal streptozotocin-induced diabetes. Main methods Sixty-four 5-day-old male rats were divided into two groups: control and diab...

Objetivo: Esta revisão da literatura visa identificar e sumarizar estudos que avaliaram os níveis de melatonina salivar em indivíduos com doença periodontal (DP). Metodologia: Realizou-se busca sistemática de publicações científicas nas seguintes bases de dados: PubMed, SCOPUS, LILACS, EMBASE, BIREME e SciELO, utilizando os termos “Doença periodont...

The relationship between maternal health and the fetal environment has been widely discussed in recent decades. Several studies have shown that insults that occur during the perinatal period modify fetal development, leading to harmful long-term results that culminate in pathologies in adulthood. Periodontal diseases (PD) comprise a wide range of i...

Introduction: Oral health is related to the systemic health of the pregnant woman and the fetus, highlighting the importance of the oral health approach as a gestational health problem. Objective: To verify the prevalence of periodontal pocket and to analyze the relationship of the condition with sociodemographic factors, medical history, and behav...

Aim: To evaluate the final step of insulin signaling, inflammatory pathway (related to the inhibition of insulin signaling), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α) protein content, and DNA methylation in the Slc2a4 gene promoter region in the skeletal muscle of adult male offspring of rats with apical periodontiti...

Health indices are important to measurement of the presence and severity of diseases. The objective of this study was to perform a literature review about malocclusion indices and analyze their applications in the public health field. The research was performed by consulting Pubmed, SciELO, Web of Science, Scopus, Bireme and Embase databases, using...

O conhecimento da relação entre o câncer de boca e fatores relacionados ao estilo de vida, como o tabagismo, etilismo e a exposição solar são conhecidos na comunidade científica, entretanto, este conhecimento também deve ser disseminado nos diversos estratos da população. Objetivou-se avaliar o conhecimento de escolares do 3º ano do ensino médio de...

Objetivo: Realizar um levantamento das lesões corporais do complexo bucomaxilofacial registradas no Instituto Médico Legal de Salvador, Bahia, para estabelecer o perfil epidemiológico das ocorrências.Materiais e métodos: Análise documental de 3600 laudos emitidos entre 2007 e 2013. Avaliou-se as características sóciodemográficas do periciado, etiol...

Objective Apical periodontitis (AP) is a chronic or acute inflammatory disease usually developed from endodontic infections, predominantly due to gram-negative anaerobic bacteria invading the dental pulp. This study aimed to evaluate lymphocyte markers to assess the involvement of adaptive immunity in insulin resistance (IR) in a rat model of AP. D...

Objetivou-se verificar a prevalência e a severidade da cárie dentária em jovens de 12 anos de um município que realiza regularmente a fluoretação das águas de abastecimento público, desde 1972, comparando as condições de saúde bucal entre jovens nascidos e não nascidos no local. Trata-se de um estudo de caso-controle, realizado em 164 escolares de...

O diabetes é uma doença crônica que representa severo problema de saúde pública. Objetivou-se avaliar aspectos relacionados à prevalência, prevenção, assistência e complicações do diabetes em adultos nas unidades federativas (UF) brasileiras. Trata-se de um estudo ecológico, documental, realizado com dados da Pesquisa Nacional de Saúde-2013 e 2019,...

Introduction: Maternal apical periodontitis (AP) is associated with insulin resistance (IR) in adult offspring. Oxidative stress has been linked to IR. This study investigated insulin sensitivity (IS) and oxidative stress in the gastrocnemius muscle (GM) of adult offspring of rats with AP. Methods: Fifteen female Wistar rats were distributed int...

The present study aimed to verify the influence of breastfeeding on children's oral and systemic health, verifying children's hospitalization, use, indication and type of antibiotics used. This is a cross-sectional longitudinal study with a sample of 42 children at 30 months of age. The logistic regression test was used at a significance level of 5...

Objetivo: analisar a dispensação de medicamentos na atenção primária do Sistema Único de Saúde em um município do Estado de São Paulo. Metodologia: realizou-se análise documental dos boletins de movimentação de medicamentos das farmácias das 19 Unidades Básicas de Saúde do município de Araçatuba-SP, sede do Departamento Regional de Saúde II-SP, dur...

Introduction: Social habits, oral health and lifestyle are important, not only from the perspective of sport development, but also from public health. Objectives: To investigate social habits, oral hygiene practices, and hydration in athletes. Methods: A cross-sectional, descriptive, survey study was conducted of 647 athletes from different sports...

Introdução: A adolescência possui peculiaridades que merecem atenção diferenciada nos serviços de saúde. Objetivos: Compreender a percepção dos adolescentes sobre saúde bucal e identificar suas atitudes, espaços e comportamentos. Métodos: Pesquisa qualitativa com 44 adolescentes, de 12 a 17 anos, de escolas de bairros periféricos de um município pa...

The present study, aimed to evaluate the effects of resistance training (RT) on glycemia, insulinemia, insulin sensitivity, insulin signaling (IS), and tumor necrosis factor-α (TNF-α) levels in rats with periodontitis. 40 male Wistar rats were distributed into 4 groups: sedentary control group (SCN), exercised control group (ExCN), sedentary ligatu...

O tratamento das oclusopatias em um sistema de saúde pública requer o levantamento de dados sobre as necessidades ortodônticas de uma determinada população. Dessa forma, diferentes métodos de registro foram desenvolvidos para classificar os problemas de oclusão. O objetivo neste estudo foi investigar a prevalência das oclusopatias e a necessidade n...

Aim To verify the effects of melatonin supplementation on insulin sensitivity, plasma concentrations of inflammatory cytokines, insulin signaling and inflammatory pathways in the soleus (SM) and extensor digitorum longus (EDL) muscles of rats with apical periodontitis (AP). Methodology Seventy‐two Wistar rats were distributed in 4 groups: a) contr...

Resumo Objetivo Analisar a condição de saúde bucal em idosos do município de Bocoio, província de Benguela, Angola, Africa. Métodos Estudo epidemiológico, transversal e analítico, realizado com 213 idosos, em 2019. Por meio de entrevistas e exames clínicos, analisou-se o perfil sociodemográfico; percepção de saúde bucal; higiene oral; uso de serviç...

Objetivo: realizar um levantamento epidemiológico das notificações de violência registradas no Departamento Regional de Saúde de São Paulo, Brasil, instituição responsável por 40 municípios do noroeste paulista. Metodologia: trata-se de um estudo transversal, com pesquisa no banco de dados do Departamento Regional de Saúde de São Paulo, analisando...

Introduction: Epidemiological analysis of buco-maxillo-facial (BMF) fractures is important to provide measures for preventive care and effective treatment of these injuries. Objectives: To verify the prevalence of sport-related accidents involving the BMF structure and factors associated with sport modality, and knowledge and use of mouthguards. Me...

Objective: to investigate dental auxiliaries (DA) hepatitis B immunization in Brazilian National Health System (SUS) services in nine cities in São Paulo State, Brazil, in 2018. Methods: this was a cross-sectional study based on interviews using a questionnaire as well as evaluation of immunity using the anti-HBs test, evaluation of prior testin...

The control of dental plaque by chemical means can be a valuable auxiliary resource for individuals who have difficulties in performing dental plaque control through regular oral hygiene procedures. The aim of this study was to evaluate the effect of chlorhexidine and fluorine varnishes on the levels of Streptococcus mutans (S. mutans) present in t...

Introdução: Os transtornos alimentares são caracterizados como distúrbios do comportamento alimentar, associados ao desequilíbrio nos pensamentos, ações e atitudes dos indivíduos resultando em prejuízos à saúde do indivíduo. Estas condições são cada vez mais comuns na sociedade atual e têm ganhado crescente atenção da comunidade científica. Objetiv...

Background: Anorexia and bulimia nervosa can have significant effects on oral health. Assessment of enzyme concentrations in saliva can be useful for obtaining information on molecular biomarkers for the prevention, monitoring and diagnosis of oral diseases. This study investigated the periodontal condition, changes in salivary biochemical paramet...

Introduction: Occupational exposure is a major risk factor for hepatitis B (HB) transmission. Methods: Vaccination coverage and immunity verification from 64 dentists of the Brazilian Unified Health System were investigated. An immunochromatographic method was used to verify immunity against the disease. Results: Overall, 77.77% of participati...

Background: Adverse stimuli applied during early fetal development can increase the risk of diseases in adulthood. Aim: This study investigated the plasma concentrations of glucose, insulin, and tumor necrosis factor-α (TNF-α) of rats with maternal apical periodontitis (AP). We also explored the effect of maternal inflammation on the initial steps...

Background The aim was to analyze the levels of stress of edentulous patients through the state-trait anxiety inventory (STAI) and salivary flow through the visual analogue scale (VAS) xerostomia questionnaire, as well as analyze the levels of cortisol, capillary blood glucose, and blood pressure (BP) before and after the installation of complete d...

Objective: To investigate the effects of sitagliptin, a dipeptidyl peptidase 4 inhibitor used to treat type II diabetes, on bone tissue and on implant osseointegration in diabetic rats. Design: Thirty-two male rats were divided into four groups: 1) Diabetic animals (GD); 2) Diabetic animals that received sitagliptin (GDS); 3) Normoglycemic anima...

Aim To investigate the plasma concentrations of glucose, insulin and tumour necrosis factor‐α (TNF‐α) of rats with maternal apical periodontitis (AP) and to explore the effect of maternal inflammation on the initial steps of insulin signalling and the inflammatory pathway in the gastrocnemius muscle (GM) and periepididymal white adipose tissue (pWA...

Background Maternal periodontal disease leads to low birth weight (LBW), insulin resistance (IR), increased TNF‐α levels and alterations in insulin signaling in adult offspring. TNF‐α has been associated with the stimulation of IKKβ/NF‐κB, resulting in the decreased expression of GLUT4. Another mechanism that may be involved in decreasing GLUT4 exp...

Excessive fluoride intake is associated with systemic metabolic alterations similar to those observed in type 2 diabetes such as decreased insulin secretion, impaired glycemic control, and insulin resistance. However, the underlying mechanisms for these changes are not fully understood. This study aimed to evaluate the effect of chronic NaF intake...

8º Congresso de Odontologia de Araçatuba, 38º Jornada Acadêmica: Prof. Dr. Mauro Airton Rulli, 14º Simpósio Pós-Graduação Profa. Dra. Kikue Takebayashi Sassaki, 10º Encontro do CAOE, Encontro de 40 anos de Egressos de Pós-Graduação em Odontologia (Área de C.T.B-M-F)

Aim This study aimed to investigate the effects of melatonin (ME) on insulin resistance (IR) and signaling (IS), proinflammatory cytokine levels, and lipid profiles in pinealectomyzed (PNX) rats with periodontal disease (PD). Main methods One hundred and forty-four rats (age = 40 days) were distributed into 8 groups: 1) control (CN); 2) PD only; 3...

Aim: This study evaluated the interface between glass ionomer cement (GIC) and dentin using the conventional and atraumatic restorative treatment (ART) techniques for removal of decayed tissue. Materials and Methods: After preparation of the cavities by the conventional (Group I – GI) and ART (Group II – GII) techniques, the specimens were divided...

Objectives The aim of this study was to determine whether the presence of single or multiple apical periodontitis (AP) alters blood cell counts and cytokine production. Material and methodsThirty rats were divided into three groups: a control group comprising rats without AP, a group called 1AP comprising rats with AP in one tooth, and a group call...

Introduction: Our previous studies have shown that periapical lesions (PLs) in rats cause systemic disorders such as increased tumor necrosis factor-α plasma levels, insulin resistance, and impairment in insulin signal transduction in muscle tissue. However, the mechanisms involved in these alterations are not fully understood. Under chronic infla...

Fluoride is an essential trace element for the maintenance of bone health owing to its capacity to stimulate proliferation and osteoblastic activity that can lead to increased bone formation. However, excessive sodium fluoride (NaF) intake can impair carbohydrate metabolism thereby promoting hyperglycemia, insulin resistance, and changes in insulin...

Introdução: Quanto ao uso do flúor na odontologia, a fluoretação das águas de abastecimento público se constitui o método de maior abrangência, além de possuir um baixo custo e ser seguro, porém a análise periódica dos níveis do íon se faz necessária para que se obtenha o máximo benefício na prevenção de cárie e risco mínimo no desenvolvimento de f...

Objectives Periapical lesion (PL) promotes insulin resistance; however, the mechanisms underlying this alteration are not fully understood. Therefore, in this study, we aimed to evaluate the Akt serine phosphorylation status and GLUT4 expression levels in the gastrocnemius muscle (GM) of rats with PL. Materials and methods Male Wistar rats (n = 42)...

Osteoporosis is a systemic disease characterized by bone degradation and decreased bone mass that promotes increased bone fragility and eventual fracture risk. Studies have investigated the use of sodium fluoride (NaF) for the treatment of osteoporosis. However, fluoride can alter glucose homeostasis. The aim of this study was to evaluate the effec...

Pregnancy is a period involving important metabolic changes that enable the maintenance of the mother's health and development of the fetus. This study aimed to assess the relationship among periodontal disease, insulin resistance, salivary cortisol concentration and level of perceived stress in pregnant women. This was a cross-sectional study. The...

Aims: The fetal programming hypothesis suggests that intrauterine stimuli can induce metabolic changes in offspring, increasing the disease risk in adulthood. Periodontal disease may enhance serum cytokine levels. Cytokines such as tumor necrosis factor-alpha (TNF-α) have been associated with reduced glucose transporter type 4 (GLUT4) expression,...

Excessive fluoride ion (F) intake promotes systemic metabolic alterations, such as a decrease in insulin secretion, hyperglycemia, and insulin resistance, similar to those observed in diabetes. Cardiovascular disease is responsible for a large degree of morbidity and mortality in individuals with diabetes, and dyslipidemia is considered to be one o...

Serum inflammatory cytokines derived from oral inflammation are associated with decreased insulin signaling (IS) and insulin resistance, which is a major risk factor for type 2 diabetes mellitus. This study aimed to investigate IS in the liver and skeletal muscle (SM) and disorders related to the serum lipid profile and glucose and insulin levels o...

Fluoride has been used in the treatment of osteoporosis and in the prevention of dental caries. However, excessive fluoride intake causes significant systemic alterations in animals and human beings. In this chapter disturbances induced in glucose homeostasis are discussed: hyperglycemia, impaired glucose tolerance and modification of metabolic pat...

Inflammatory cytokines are associated with decreased insulin signal transduction. Moreover, local oral inflammation, such as that accompanying periodontal disease, is associated with insulin resistance and type 2 diabetes mellitus. The aim of this study was to evaluate the effect of periapical lesions (PLs) on insulin signaling and insulin sensitiv...

The current study aimed to investigate if a pulp lesion, which is a local inflammatory disease, can promote alterations in insulin signal and insulin sensitivity (IS). Twenty‐eight two‐month‐old (230g) Wistar male rats were randomly divided into a control group (CN) and a pulp lesion group (PL). PL group was submitted to pulp lesion induction throu...

The present study aimed to evaluate the chronic effect of NaF on: 1) inhibitory pathway of insulin signal transduction in liver (L) and muscle (M); 2) plasma concentration (PC) of triglycerides (TGL); 3) total cholesterol (TC); 3) high‐density lipoprotein cholesterol (HDL‐C); 4) low‐density lipoprotein cholesterol (LDL‐C); 5) very low‐density lipop...

Excessive fluoride ion (F) intake promotes systemic metabolic alterations, such as a decrease in insulin secretion, hyperglycemia, and insulin resistance, similar to those observed in diabetes. Cardiovascular disease is responsible for a large degree of morbidity and mortality in individuals with diabetes, and dyslipidemia is considered to be one o...

Fluoridation of public water supplies is one of the most important public health advances on Public Health in the twentieth century, because is a measure of wide populational coverage, effective in control of dental caries. In May 24 1974, by the Federal law 6050, this method of fluoridation became mandatory on all Brazilian cities where there are...

Objectives: The objective of this study was to estimate the prevalence of deciduous tooth erosion and to identify possible associations with sex, age and toothbrushing frequency in children aged 4-6 years. Methods: The sample was drawn from attendants (n = 7058) of 57 public preschools in a Brazilian city. Tooth wear index was used to evaluate e...

Objectives: Fluoride levels in the public water supplies of 40 Brazilian cities were analyzed and classified on the basis of risk/benefit balance. Material and methods: Samples were collected monthly over a seven-year period from three sites for each water supply source. The samples were analyzed in duplicate in the laboratory of the Center for...

Known as one of the ten most important advances on Public Health in the 20th century, fluoridation of public water supply is a measure of wide population coverage, which is effective on caries control. The city of Araçatuba, in the Northwest region of the São Paulo state, Brazil, started public water supply fluoridation in 1972 and, based on the av...

Fluoride is known to cause both local and systemic alterations in animals and humans, such as dental fluorosis and disturbances in glucose homeostasis. The effects of fluoride are dose dependent and can produce decreased insulin secretion, inhibition of glycolysis, glycogen depletion, hyperglycemia, and insulin resistance. Because excessive ingesti...

Background: Periodontal disease during pregnancy has been recognized as one of the causes of preterm and low-birth-weight (PLBW) babies. Several studies have demonstrated that PLBW babies are prone to developing insulin resistance as adults. Although there is controversy over the association between periodontal disease and PLBW, the phenomenon kno...

The use of fluoridated products has significantly contributed to the reduction in rates of dental caries. However, excessive sodium fluoride (NaF) intake promotes inhibition of glycolysis, decrease in insulin secretion, hyperglycemia, and insulin resistance. Seven-week-old castrated male Wistar rats were used to evaluate the chronic effect of NaF o...

The fluoridation of public water supplies is considered the most efficient public health measure for dental caries prevention. However, fluoride levels in the public water supply must be kept constant and adequate for the population to gain preventive benefit. The aim of this study was to analyze fluoride levels in the public water supply of 29 Bra...