Fernando A Barrios

Fernando A Barrios
Universidad Nacional Autónoma de México | UNAM · Instituto de Neurobiología

PhD

About

167
Publications
27,041
Reads
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1,918
Citations
Citations since 2016
51 Research Items
1147 Citations
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
Additional affiliations
September 2013 - September 2014
Massachusetts Institute of Technology, McGovern Institute for Brain Research
Position
  • Researcher
Description
  • Sabbatical leave from UNAM
September 2007 - September 2011
Instituto Nacional de Neurología y Neurocirugía
Position
  • Investigador de la UNAM asociado al INNN
September 2002 - August 2003
Université Victor Segalen Bordeaux 2
Position
  • Researcher
Description
  • Sabbatical leave from UNAM
Education
September 1986 - June 1991
University of Cincinnati
Field of study
  • Theoretical Physics

Publications

Publications (167)
Article
Full-text available
The Emotion Regulation Questionnaire (ERQ) measures the use of two emotional regulation strategies, cognitive reappraisal, and expressive suppression. Although widely used, there is no description of the psychometric properties of the ERQ and its correlations with alexithymia and empathy in a Mexican sample. We examine the psychometric properties o...
Article
Full-text available
Different theoretical models have proposed cognitive and affective components in empathy and moral judgments encompassing compassion. Furthermore, gender differences in psychological and neural functions involving empathic and moral processing, as well as compassionate experiences, have been reported. However, the neurobiological function regarding...
Article
Full-text available
Empathic abilities have been shown to be linked with brain structural variations. Since psychotherapists constitute a population that tends to display greater empathic abilities, as shown in psychometric differences in cognitive empathy and emotional regulation, we aimed to identify cortical thickness (CT) differences between a group of professiona...
Article
Modulation of reflex responses is crucial to adapt our behavior and cognition, and this is especially difficult when biological relevant stimuli are present such as emotional faces. The aim of this study was to identify the effect of peripherally presented happy and angry facial expressions in reflexive saccades and saccadic inhibition/re-orientati...
Article
Full-text available
During a social evaluation, the right temporo-parietal junction (rTPJ) plays an important role according to its contribution in making inferences about the mental states of others. However, what is the neural response if rTPJ function is inhibited during a mentalizing task? In this study, participants played the Dictator Game with two confederates:...
Article
In a therapeutic environment a proper regulation of the empathic response strengthens the patient-therapist relationship. Thus, it is important that psychotherapists constantly regulate their own perspective and emotions to better understand the other’s affective state. We compared the empathic abilities of a group of 52 psychotherapists with a gro...
Article
Full-text available
This paper shows the brain correlates of Cloninger's personality model during the presentation of social scenarios under positive or negative valence situations. Social scenarios were constructed when participants played the Dictator game with two confederates that had two opposites roles as the cooperator (Coop) and non-cooperator (NoCoop). Later...
Article
Full-text available
The cortical thickness has been used as a biomarker to assess different cerebral conditions and to detect alterations in the cortical mantle. In this work, we compare methods from the FreeSurfer software, the Computational Anatomy Toolbox (CAT12), a Laplacian approach and a new method here proposed, based on the Euclidean Distance Transform (EDT),...
Article
Full-text available
Focused attention to spontaneous sensations is a dynamic process that demands interoceptive abilities. Failure to control it has been linked to neuropsychiatric disorders like illness-anxiety disorder. Regulatory strategies, such as focused attention meditation (FAM), may enhance the ability to control focused attention particularly to body sensati...
Article
Brainhack is an innovative meeting format that promotes scientific collaboration and education in an open, inclusive environment. This NeuroView describes the myriad benefits for participants and the research community and how Brainhacks complement conventional formats to augment scientific progress.
Preprint
Full-text available
It's now common to approach questions about information representation in the brain using multivariate statistics and machine learning methods. What is less recognized is that, in the process, the capacity for data-driven discovery and functional localization has diminished. This is because multivariate pattern analysis (MVPA) studies tend to restr...
Preprint
Full-text available
Brainhack is an innovative meeting format that promotes scientific collaboration and education in an open and inclusive environment. Departing from the formats of typical scientific workshops, these events are based on grassroots projects and training, and foster open and reproducible scientific practices. We describe here the multifaceted, lasting...
Article
Full-text available
Adolescence is a developmental period that dramatically impacts body and behavior, with pubertal hormones playing an important role not only in the morphological changes in the body but also in brain structure and function. Understanding brain development during adolescence has become a priority in neuroscience because it coincides with the onset o...
Preprint
The Emotion Regulation Questionnaire (ERQ) is widely used to measure the individual differences in two emotion regulation strategies: cognitive reappraisal and expressive suppression. In this study, we examine the psychometric properties of the ERQ (Spanish version) in a Mexican community sample (N = 792). Exploratory and confirmatory factor analys...
Preprint
Full-text available
Empathic capacity has been shown to be correlated with brain structural variations. This study investigates how this is the case in a group of psychotherapists who have a constant demand to modulate their empathic response. Eighteen psychotherapists and eighteen healthy controls underwent 3 Tesla MRI scanning and completed empathy related psychomet...
Article
Full-text available
Working Memory (WM) deficits have been suggested as an endophenotypic marker for schizophrenia. This neurocognitive marker proposal has been supported by evidence of WM deficits also observed in unaffected high-risk relatives (HR) of patients with schizophrenia. Furthermore, empirical evidence suggests that working memory (WM) load and the implicit...
Preprint
Full-text available
Adolescence is a developmental period that dramatically impacts body and behavior, with pubertal hormones playing an important role not only in the morphological changes in the body but also in brain structure and function. Understanding brain development during adolescence has become a priority in neuroscience because it coincides with the onset o...
Preprint
Full-text available
Psychotherapists constantly regulate their own perspective and emotions to better understand the other state. We compared 52 psychotherapists with 92 non-psychotherapists to characterized psychometric constructs like, Fantasy (FS) and Perspective Taking (PT), and the emotion regulation strategy of Expressive Suppression (ES), which hampers the empa...
Article
Full-text available
Semantic verbal fluency is among the most employed tasks in cognitive aging research and substantial work is devoted to understanding the underlying mechanisms behind age-related differences at the neural and behavioral levels. The present investigation aimed to evaluate the role of moderating variables, such as age, sex, MMSE, and proxies of cogni...
Preprint
Full-text available
Focused attention to spontaneous sensations is a phenomenon that demands interoceptive abilities and a dynamic character of attentive processes. The lack of its control has been linked to neuropsychiatric disorders, such as illness-anxiety disorder. Regulatory strategies, like focused attention meditation, may enhance the ability to control attenti...
Article
Full-text available
While brain default mode network (DMN) activation in human subjects has been associated with mind wandering, meditation practice has been found to suppress it and to increase psychological well-being. In addition to DMN activity reduction, experienced meditators (EMs) during meditation practice show an increased connectivity between the DMN and the...
Article
Full-text available
A voxel-based method for measuring sulcal width was developed, validated and applied to a database. This method (EDT-based LM) employs the 3D Euclidean Distance Transform (EDT) of the pial surface and a Local Maxima labeling algorithm. A computational phantom was designed to test method performance; results revealed the method's inaccuracy δ, to ra...
Article
Full-text available
Listening to self-chosen, pleasant and relaxing music reduces pain in fibromyalgia (FM), a chronic centralized pain condition. However, the neural correlates of this effect are fairly unknown. In our study, we wished to investigate the neural correlates of music-induced analgesia (MIA) in FM patients. To do this, we studied 20 FM patients and 20 ma...
Article
Full-text available
How do humans discriminate emotion from non-emotion? The specific psychophysical cues and neural responses involved with resolving emotional information in sound are unknown. In this study we used a discrimination psychophysical-fMRI sparse sampling paradigm to locate threshold responses to happy and sad acoustic stimuli. The fine structure and env...
Article
Full-text available
Humans perceive musical sound as a complex phenomenon, which is known to induce an emotional response. The cues used to perceive emotion in music have not been unequivocally elucidated. Here, we sought to identify the attributes of sound that confer an emotion to music and determine if professional musicians have different musical emotion perceptio...
Article
Full-text available
The Environmental Psychological Restoration (EPR) is the result of the recovery of an antecedent deficit (e.g. stress or attentional fatigue) culminating in a restorative environment exposure. Recent findings suggest that visual contact with nature is important in triggering restorative responses. We measure the behavioral evidence of visual exposu...
Preprint
Full-text available
The claustrum is an irregular and fine sheet of grey matter in the basolateral telencephalon present in almost all mammals. The claustrum has been the object of several studies using animal models and more recently in human beings using neuroimaging. It has been involved in cognition and disease such as fear recognition, suppression of natural urge...
Article
Full-text available
Sparse sampling functional MRI (ssfMRI) enables stronger primary auditory cortex blood oxygen level-dependent (BOLD) signal by acquiring volumes interspersed with silence, reducing the physiological artifacts associated with scanner noise. Recent calculations of type I error rates associated with resting-state fMRI suggest that the techniques used...
Article
Full-text available
Alzheimer's disease (AD) is characterized in the late stages by amyloid-β (Aβ) plaques and neurofibrillary tangles. Nevertheless, recent evidence has indicated that early changes in cerebral connectivity could compromise cognitive functions even before the appearance of the classical neuropathological features. Diffusion tensor imaging (DTI), resti...
Poster
Full-text available
Empathy has been conceived as a pivotal function for successful social interactions. It has been defined as the ability to share the emotional experience of others ("I feel what you feel"). Among others, one of the main brain areas related with empathy has been the temporo-parietal junction mainly in the right hemisphere (rTPJ). Brain areas related...
Poster
Full-text available
Impressions about other individuals have an impact on the way we react when we know about situations that they suffer. Although this process sometimes exist under the surface of our consciousness, this is a highly common reaction that has an impact on each relationship in our lives. However scarce number of studies has explore how the brain classif...
Poster
Full-text available
Music-induced analgesia is correlated with resting-state functional connectivity of pain-related brain areas.
Article
Full-text available
Anthropomorphism implies the attribution of human like emotions and cognition to non-human animals. This tendency may be conditioned by similar morphologies between mammals and is particularly important in primatology. Some neurocognitive findings suggest that prefrontal brain activity associated to conceptual learning influences anthropomorphic ju...
Article
Full-text available
Studies based on a paradigm of free or natural viewing have revealed characteristics that allow us to know how the brain processes stimuli within a natural environment. This method has been little used to study brain function. With a connectivity approach, we examine the processing of emotions using an exploratory method to analyze functional magne...
Article
Hemispheric specialization of cognitive functions is a developmental process that shapes the brain from the gestational stage to adulthood. Functional connectivity of the resting brain has been largely used to infer the hemispheric organization of the spontaneous brain activity. In particular, two main properties have been largely explored througho...
Preprint
Full-text available
Listening to self-chosen, pleasant and relaxing music reduces pain in fibromyalgia (FM), a chronic central pain condition. However, the neural correlates of this effect are fairly unknown and could be regarded as a more direct measure of analgesia. In our study, we wished to investigate the neural correlates of music-induced analgesia (MIA) in fibr...
Article
Orthographic competence allows automatic word recognition and reading fluency. To elucidate how the orthographic competence in Spanish-speaking adults might affect the neurofunctional mechanisms of visual word recognition, 32 young adults equally divided in two groups (HSS: High Spelling Skills, and LSS: Low Spelling Skills) were evaluated using fM...
Preprint
Emotion is known to activate different areas of the cortex; nevertheless, how activation represents the variety of emotion is unknown. We asked whether functional activation in Heschl’s gyrus and amygdala subdivisions could differentiate happy and sad acoustic stimuli. A sparse sampling fMRI paradigm assessing hemispheric laterality by subdivision...
Article
The current study investigated the neural basis of reading performance in 60 school-age Spanish-speaking children, aged 6 to 9years. By using a data-driven approach and an automated matching procedure, we identified a left-lateralized resting state network that included typical language regions (Wernicke's and Broca's regions), prefrontal cortex, p...
Preprint
Studies based on a paradigm of free or natural viewing have revealed characteristics that allow us to know how the brain processes stimuli within a natural environment. This method has been little used to study brain function. With a connectivity approach, we examine the processing of emotions using an exploratory method to analyze functional magne...
Article
Full-text available
Mentalizing is a fundamental aspect of social cognition that includes understanding the mental states of others. This process involves the participation of a well-defined set of brain regions. However, it is still unknown how different contextual situations, such as previous cooperative or non-cooperative interactions, can modulate the brain activi...
Article
Full-text available
Brainhack events offer a novel workshop format with participant-generated content that caters to the rapidly growing open neuroscience community. Including components from hackathons and unconferences, as well as parallel educational sessions, Brainhack fosters novel collaborations around the interests of its attendees. Here we provide an overview...
Article
Full-text available
Background and purpose: There is a scarcity of information on the effect of white matter degeneration in patients with spinocerebellar ataxia type 7. Therefore, we investigated the WM integrity in a large group of patients with spinocerebellar ataxia type 7 by using Tract-Based Spatial Statistics. Materials and methods: Thirty-three patients wit...
Conference Paper
Full-text available
Introduction: Functional connectivity is modulated by stressor events (Gold, 2015). Once the stressor disappears, a restorative process returns the homeostatic state. Images with natural environments have the ability to enhance the restorative process, while urban environments have no properties to facilitate such process (Martinez-Soto, 2014). The...
Article
Full-text available
Excess theta electroencephalographic (EEG) activity has been described as an accurate predictor for cognitive decline at least 7 years before symptom presentation. To test whether this predictor for cognitive decline correlates with structural changes in the brains of healthy elderly individuals, we compared the magnetic resonance structural images...
Article
Evolutionary approaches have proposed that women possess an advantage over men in emotional functioning to promote attachment for child-rearing. Likewise, sex differences have been reported in traits such as personality and empathy, traits that likely modulate emotional processing. In this preliminary study, sex differences in emotional processing...
Article
Full-text available
Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia (MIA) are still largely unknown. We recruited FM patients (n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 min without external noise from fMRI image acquisition. Resting...
Article
-The present study evaluated images of environments in three categories with different affective and restorative valences through two computerized assessments. A non-verbal computerized response scale and the Mexican Scale of Environmental Restoration Perception were employed. 104 students assessed the affective qualities of 117 images (47 natural,...
Article
Full-text available
Using functional Magnetic Resonance Imaging (fMRI) it is possible to study the functional anatomy of primary cortices. Cortical representations in the primary somatosensory cortex have shown discrepancies between activations related to the same body region in some studies; these differences have been more pronounced for lower limb representations....
Article
Full-text available
Compassion is a prototypical moral emotion supporting cooperation and involves empathic decision-making and motor processes representing the interplay of biologically evolved and cultural mechanisms. We propose a social neuroscience approach to identify gender differences and to assess biological and cultural factors shaping compassion. We consider...
Article
Full-text available
Technical advances and methodological issues in measuring functional and structural brain connectivity: multimodal human imaging methods, animal models, and applications in neurological and psychiatric diseases.