Fermin Medina Varo

Fermin Medina Varo
  • Senior Researcher at Hospital Universitario Puerta del Mar, Cádiz

About

17
Publications
3,041
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214
Citations
Introduction
Current institution
Hospital Universitario Puerta del Mar, Cádiz
Current position
  • Senior Researcher

Publications

Publications (17)
Poster
Full-text available
La leucemia linfática crónica (LLC) es la leucemia más frecuente en adultos en países occidentales. Suele presentarse en mayores de 70 años, predominantemente hombres. El curso clínico es variable apareciendo en algunos casos un comportamiento agresivo con progresión rápida de la enfermedad y posible transformación a linfoma de alto grado (2-8%). L...
Article
Objectives: To analyse the risk of fracture calculated by FRAX® and the frequency of high risk of fracture in the general population in Spain. Methods: EPISER2016 is a multicentre cross-sectional population-based study of the prevalence of rheumatic diseases in the adult population in Spain. 3,154 subjects aged ≥40 years (1,184 men and 1,970 wom...
Article
Full-text available
Systemic lupus erythematosus and rheumatoid arthritis are autoimmune diseases characterised by B‐cell hyperactivation and production of autoantibodies (AutoAbs) against various self‐antigens, including extractable nuclear antigens and citrullinated peptides. Therefore, B lymphocytes and antibody‐secreting cells are considered relevant targets for t...
Article
Aims To describe the methodology of the EPISER 2016 (study of the prevalence of rheumatic diseases in adult population in Spain), as well its strengths and limitations. The aim of this study is to estimate the prevalence of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), Sjögren...
Article
We describe a successful desensitization to alemtuzumab in one patient diagnosed with T-cell prolymphocytic leukaemia. Alemtuzumab treatment was initiated during infusion number 18, the patient showed cutaneous eruption with a miliary pattern, despite premedication with corticosteroids and antihistamines. The eruption returned with successive alemt...
Article
Full-text available
Aims: To describe the methodology of the EPISER 2016 (study of the prevalence of rheumatic diseases in adult population in Spain), as well its strengths and limitations. The aim of this study is to estimate the prevalence of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), Sjögr...
Article
Disturbances of plasma cell homeostasis and auto‐antibody production are hallmarks of systemic lupus erythematosus. The aim of this study was to explore the presence of circulating anti‐ENA and anti‐dsDNA antibody‐secreting cells, to determine their dependence on plasma cell‐niche cytokines and to analyze their clinical value. The study was perform...
Article
Full-text available
Denosumab is a human monoclonal antibody indicated for the treatment of osteoporosis in postmenopausal women with a high risk of fractures. To our knowledge, no cases of desensitization to this drug have been described in the literature. We report the first case of generalized urticarial reaction and facial angioedema after therapy with denosumab....

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