Felix Tomi

Felix Tomi
University of Corsica Pascal Paoli · Laboratoire des Sciences Pour l’Environnement SPE - UMR 6134

Professor
phytochemistry

About

326
Publications
89,745
Reads
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7,029
Citations
Introduction
Phytochemistry, Analytical chemistry, Methodology of computerized NMR: Analysis of complex natural mixtures by NMR, Chromatography, Mass spectrometry, Essential oils, extracts, Citrus
Additional affiliations
January 2008 - December 2017
University of Corsica Pascal Paoli
Position
  • Managing Director
January 2013 - present

Publications

Publications (326)
Article
Full-text available
It is well-known that geijerene is mostly associated with pregeijerene. These terpenes are believed to be thermoconvertible by a type of sigmatropic transposition order supra or antarafaciale. Our contribution to the study of the molecular pair consisted on a combination of statistical and analytical approach to the chemical composition of Chromola...
Article
Thirty‐seven essential oil samples have been isolated from leaves of individual plants of Juniperus oxycedrus (subspecies oxycedrus and macrocarpa) growing wild in Tlemcen and Aïn Témouchent provinces (Northwestern Algeria). Analysis of eight selected oil samples by GC(RI), GC/MS and 13C NMR, allowed the identification of 88 components that account...
Article
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Helichrysum italicum (Roth) G. Don is a Mediterranean medicinal plant with great potential in the cosmetics, culinary and pharmaceutical fields due to its unique bioactive compounds. Its recent introduction into agroecosystems has enhanced the exploitation of genetic diversity in natural populations, although limited molecular markers have made thi...
Article
The chemical composition of 33 oil samples isolated from the berries of individual trees of two subspecies of Juniperus oxycedrus L., collected in four locations in Tlemcen and Aïn Temouchent provinces, was investigated by GC‐FID, GC/MS and 13CNMR. In total, 83 compounds were identified, accounting for 85.9% to 98.6% of the total composition. Yield...
Article
The chemical composition of 71 oil samples from the leaves of Rosmarinus officinalis L., harvested in three provinces: Naâma (Western Algeria), Béchar and Adrar (Algerian Sahara), was investigated by GC‐FID, GC/MS and ¹³ CNMR. In total, 52 compounds were identified accounting for 88.8 % to 99.9 % of the total composition. The chemical composition o...
Article
The essential oils (EOs) from needles, twigs and cones of Abies numidica, an endemic tree from Algeria, were analysed by gas chromatography (GC), gas chromatography-mass spectrometry (GC-MS) and 13C nuclear magnetic resonance (13C NMR). Fifty, forty-nine, and thirty-eight components from needles, twigs and cones were identified accounting for 86.0%...
Article
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Despite their importance in food processing, perfumery and cosmetics, the inheritance of sweet orange aromatic compounds, as well as their yield in the fruit peel, has been little analyzed. In the present study, the segregation of aromatic compounds was studied in an F1 population of 77 hybrids resulting from crosses between clementine and blood sw...
Article
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Glyptostrobus pensilis (Staunton ex D. Don) K. Koch is a critically endangered species, native to southeastern China and also very locally found in Dak Lak Province, Vietnam. Essential oil isolated from leaves is a monoterpene-rich oil containing mainly limonene (33.3%), α-pinene (23.4%) and bornyl acetate (9.2%). The composition of G. pensilis woo...
Article
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Cladanthus mixtus (L.) Chevall., Asteraceae, also known as Moroccan chamomile, is a spontaneous, annual plant growing wild in North-Western Morocco. Economically, the essential oil of C. mixtus is of high interest, Morocco being the only supplier on the international market. Two essential oil samples (EO) were isolated from aerial parts of Cladanth...
Article
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Seven essential oil samples of two endemic species of Malagasy sage, Salvia sessilifolia Baker and Salvia leucodermis Baker, were investigated via GC(RI), GC-MS and 13C NMR spectrometry. In total, 81compounds were identified accounting for 93.5% to 98.7% of the total composition. The main constituents for the both species were (E)-β-caryophyllene (...
Article
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The great genetic and phenotypic diversities characterize the mandarin species (Citrus reticulata). The present study aimed to evaluate a part of this diversity with molecular markers and through the composition of leaf (LEO) and fruit peel (PEO) essential oils. Seventy-two cultivars were chosen for this study to represent some wild and cultivated...
Article
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Orange (Citrus x aurantium var sinensis) is the most widely consumed citrus fruit, and its essential oil, which is made from the peel, is the most widely used in the food, perfume, and cosmetics industries. This citrus fruit is an interspecific hybrid that would have appeared long before our era and would result from two natural crosses between man...
Article
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The essential oils of Oricia suaveolens and Guibourtia ehie from Southern Côte d’Ivoire were extracted by hydrodistillation then analyzed by gas chromatography in combination with retention indices [GC(RI)], gas chromatography coupled with mass spectrometry (GC-MS) and nuclear magnetic resonance of carbone-13 (13C NMR) And described here for the fi...
Article
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Cladanthus scariosus (Ball) Oberpr. & Vogt is endemic to Moroccan High Atlas. It is known under the vernacular names Irezghi or Irezgui. Three essential oil samples have been isolated from aerial parts and analyzed by combination of chromatographic and spectroscopic techniques [gas chromatography (GC) in combination with retention indices (RI), gas...
Article
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Aims: This study aims, on the one hand, to establish the chemical composition and to evaluate the antioxidant potential of essential oils (EO) of Guarea cedrata leaves and root bark, and on the other hand, to determine the antimicrobial activity of the leaf EO. Methodology: The EOs were analyzed by a combination of GC (Ir), GC-MS and 13C NMR. The a...
Article
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The peel essential oil (PEO) of sweet orange is used for flavoring liquors or foods and in the perfumery and cosmetics industry. The fruit maturity stage can modify the essential oil composition and aromatic properties, but little information is available on the evolution of PEO during the entire time set of fruit development. In this study, the yi...
Article
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The variability of chemical composition of the leaf essential oil (EO) from Neuropeltis acuminata, a climbing liana growing wild in Ivory Coast, was investigated for the first time. The in vitro anti-inflammatory activity was also evaluated. Thirty oil samples were isolated from leaves collected in three forests of the country and analyzed using a...
Article
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The essential oil from aerial parts of Tetraclinis articulata (Vahl) Masters, obtained byhydrodistillation was analyzed by GC, GC/MS and 13C-NMR and evaluated for antimicrobialactivity. The essential oil was rich in monoterpenes which α-pinene, bornyl acetate andcamphor being the main constituents.Three essential oils were tested against Staphyloco...
Article
Citrus phylogeny is currently based on genome analysis using molecular markers and sequencing. The 7 pure genetic groups that gave rise to all cultivated citrus underlie the diversity of citrus accessions originating from Asia. However, there are wild citrus forms whose phylogenetic position is unknown, such as mountain citron (Citrus halimii B.C....
Article
Keteleeria evelyniana Mast. is a species of conifer native to southern China, Laos and Vietnam. The species has been listed as vulnerable in Vietnam. Oil samples have been isolated from leaves, twigs, roots and cones, and analyzed by combination of GC(FID), GC-MS and ¹³C NMR. The composition of leaf oil, dominated by α-pinene (37.8%) and β-pinene (...
Article
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Rootstock is widely used for the cultivation of citrus fruits because it brings resistance or tolerance to diseases or environmental constrains and modulates the fruit quality. Polyploidization is a widespread improvement strategy in citrus. The objective was to evaluate the effect of rootstock and ploidy level on the composition of essential oils....
Article
Citrus phylogeny is currently based on genome analysis using molecular markers and sequencing. The 7 pure genetic groups that gave rise to all cultivated citrus underlie the diversity of citrus accessions originating from Asia. However, there are wild citrus forms whose phylogenetic position is unknown, such as mountain citron (Citrus halimii B.C....
Article
Full-text available
The chemical variability and the in vitro anti-inflammatory activity of the leaf essential oil from Ivorian Isolona dewevrei were investigated for the first time. Forty-seven oil samples were analyzed using a combination of CC, GC(RI), GC-MS and 13C-NMR, thus leading to the identification of 113 constituents (90.8–98.9%). As the main components var...
Article
Thirty‐three oil samples isolated from aerial parts of Myrtus communis L. harvested in seven localities, from Northern to Central Morocco, have been analyzed by combination of chromatographic and spectroscopic techniques. The 33 compositions have been subjected to statistical analysis, hierarchical cluster analysis (HCA) and principal component ana...
Article
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The essential oil from aerial parts of Pituranthos scoparius obtained by hydrodistillation was analyzed by GC, GC/MS and 13C NMR and evaluated for antimicrobial and antioxidant activities. The yields were showed a very high variability ranging from 0.16 to 0.99%. Sixty two components were identified and the results indicated that the essential oil...
Article
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The Papeda Citrus subgenus includes several species belonging to two genetically distinct groups, containing mostly little-exploited wild forms of citrus. However, little is known about the potentially large and novel aromatic diversity contained in these wild citruses. In this study, we characterized and compared the essential oils obtained from p...
Article
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Sour oranges (Citrus aurantium L.) are well known in the processing and cosmetics industries for the aromatic properties of their essential oils. Intercultivar genetic and aromatic diversity is not well documented. The objective of this study was to evaluate the impact of morphological selection and genetic mechanisms of varietal diversification (m...
Article
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The growing use of herbal medicines worldwide requires ensuring their quality, safety and efficiency to consumers and patients. Quality controls of vegetal extracts are usually undertaken according to pharmacopoeial monographs. Analyses may range from simple chemical experiments to more sophisticated but more accurate methods. Nowadays, metabolomic...
Article
Cladanthus eriolepis (C. eriolepis) (Coss. ex Maire) Oberpr. & Vog. is endemic to High Atlas (Dades Gorge and Todgha Gorge), the Anti Atlas and Saharan Morocco. It is known under the vernacular names ‘Alougjim, gtaa-eddib, laatetecha’ and ‘Lamghizal’. Two essential oil samples have been isolated from aerial parts and analyzed by combination of chro...
Article
The root and stem bark essential oils from Isolona dewevrei (Annonaceae), growing wild in Côte d'Ivoire, were investigated for the first time, using a combination of chromatographic [CC, GC(RI)] and spectroscopic [MS, 13C-NMR] techniques. A new natural germacrone was isolated by repetitive column chromatography carried out on a stem bark oil sample...
Article
This study aimed to investigate the chemical composition of the leaf essential oil from Ivoirian Isolona dewevrei. A combination of chromatographic and spectroscopic techniques (GC(RI), GC-MS and 13 C-NMR) was used to analyze two oil samples (S1 and S2). Detailed analysis by repetitive column chromatography (CC) of essential oil sample S2 was perfo...
Article
Pinus krempfii Lecomte is endemic to the central highlands of Vietnam. It is also known as Krempf’s pine or flat-needled pine. Two essential oil samples have been isolated from leaves and branches, respectively, and analyzed by a combination of chromatographic and spectroscopic techniques [GC(FID), GC-MS and ¹³C NMR]. The compositions of both oil s...
Article
This work is a contribution to the characterization of aromatic and medicinal plants from Côte d’Ivoire. To date, no phytochemical investigation was reported on Isolona dewevrei. Thus, the aim of this study was to investigate for the first time, the chemical composition of the leaf essential oil from I dewevrei. Two essential oil samples (S1, S2) w...
Article
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The cosmetic and fragrance industry largely exploits citrus essential oils (EOs) because of their aromatic properties. EO compositions are complex and differ between fruit pericarp (PEO) and leaf (LEO). Citrus fruit grow in many countries under very different climates. Seventeen citrus cultivars were selected and their similarities between the two...
Article
Full-text available
The cosmetic and fragrance industry largely exploits citrus essential oils (EOs) because of their aromatic properties. EO compositions are complex and differ between fruit pericarp (PEO) and leaf (LEO). Citrus fruit grow in many countries under very different climates. Seventeen citrus cultivars were selected and their similarities between the two...
Article
Full-text available
This work aims to study the variations in the composition of Lantana camara leaf, flower, and stem essential oils over two years. L. camara organs were harvested in Bregbo (East Côte dʹIvoire) each month from June 2015 to June 2017. The essential oils were obtained by hydrodistillation and characterized by GC-MS and 13 C NMR. Eighty-four compounds...
Article
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Low temperatures during winter are one of the main constraints for citrus crop. Polyploid rootstocks can be used for improving tolerance to abiotic stresses, such as cold stress. Because the produced fruit are seedless, using triploid scions is one of the most promising approaches to satisfy consumer expectations. In this study, we evaluated how th...
Article
Cymbopogon schoenanthus (L.) Sprengel (Poaceae) is an aromatic plant whose aerial parts and rhizome produced an essential oil with pleasant odor. A chemical variability has been observed depending of the countries where the plant grows wild, including Algeria. The chemical compositions of 24 oil samples isolated from plants harvested in Central Alg...
Article
Full-text available
The essential oils of six endemic Malagasy Helichrysum species were investigated by GC (RI), GC-MS and 13 C NMR spectrometry. In total, 153 compounds were identified accounting for 90.8% to 99.9% of the total composition. The main constituents were α-pinene for H. benthamii, 1,8-cineole for H. dubardii, (E)-β-caryophyllene for H. indutum, and H. bo...
Poster
Full-text available
References-Ghisalberti, E.L. Lantana camara. Fitoterapia 2000, 71, 467-486.-Patel, S. A weed with multiple utility: Lantana camara. Rev. Environ. Sci. Biotechnol. 2011, 10, 341-351.-Saxena, M.; Saxena, J.; Khare, S. A brief review on : Therapeutical values of Lantana camara plant. Int. Journal Pharmacy Life Sciences 2012, 3, 1551-1554. Conclusion I...
Article
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In this study, the chemical variation of the essential oils of the endemic species Origanum elongatum has been studied in its biogeographical context. Essential oils of 168 individual plants collected from 30 populations growing wild in two Moroccan mountains: Rif and Middle Atlas, were analyzed by GC-FID (Gas Chromatography with Flame Ionization D...
Article
The chemical composition of 44 leaf oil samples of Laggera pterodonta (DC.) Sch. Bip. ex Oliv. (Asteraceae) from Côte d’Ivoire was investigated, using combination of chromatographic (GC‐FID) and spectroscopic (GC/MS, 13 C NMR) techniques. Two oil samples chosen according to their chromatographic profiles were submitted to column chromatography and...
Article
Citrus fruits have been introduced to the Mediterranean area from Asia for centuries and spontaneous crosses have generated several hybrid forms, some of which have had agricultural or industrial success while others have remained niche food or ornamental products, or have disappeared. Pompia (C. medica tuberosa Risso & Poiteau) is an old endemic c...
Article
This study made it possible to characterise by GC (in combination with retention indices), GC-MS and ¹³C NMR, the chemical composition of the essential oils from Solanum rugosum and Solanum erianthum, two Solanaceae of the Ivorian flora. The two essential oils were characterised by a very high proportion of sesquiterpenes. Specifically, the essenti...
Article
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The combination of ¹³ C nuclear magnetic resonance (NMR) spectroscopy, gas chromatography (GC) (retention index), and gas chromatography-mass spectrometry was used to determine the chemical composition of essential oils of Piper guineense and Piper umbellatum from Côte d’Ivoire. Thus, 54 components, accounting for 91.5% to 97.6%, were identified in...
Article
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Oregano herbs and essential oils are considered of great interest for their medicinal virtues as well as for their culinary properties. The present investigation aims to study the chemical diversity of the essential oils (EO) of a rare Origanum species (O. grosii) endemic to the North-West of Morocco based on a large sample size (68 individual plan...
Article
Full-text available
Myrtus communis L. is a shrub growing wild in most countries all around the Mediterranean Sea and myrtle leaf oil is useful in the perfumery and pharmaceutical industries. Nowadays, “chemotyped” essential oils are more and more appreciated. Myrtle oil from eastern and central-north Algeria belong to the “α-pinene-cineole” chemotype. In contrast, Mo...
Article
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Conifers are well represented in Vietnam where a new pine species has been recently discovered in Son La province: Pinus cernua, synonym P. armandii ssp. xuannhaensis. The compositions of needle, cone, and branch oils have been investigated by gas chromatography (retention index), gas chromatography-mass spectrometry, and ¹³C nuclear magnetic reson...
Article
Nine samples of Xylopia rubescens Oliv. (Annonaceae) trunk bark oil have been analyzed by combination of GC(RI) and 13C NMR. The contents of the major components varied substantially from sample to sample: (8Z,11Z,14Z)-heptadeca-8,11-14-trien-2-one (14.7-33.0%), furanoguaia-1,4-diene (0-36.8%) and β-pinene (0.9-29.0%). The content of a few componen...
Article
The investigation of the stem essential oil of Laggera pterodonta (DC.) Sch. Bip. ex Oliv. (Asteraceae) from C^ ote d'Ivoire was carried out, using a combination of chromatographic (GC-RI, CC, pc-GC) and spectroscopic (GC-MS, 13 C NMR) techniques. This study led to the identification of fifty constituents of which two new natural compounds 7b,11b-e...
Article
Essential oils (EOs) obtained from aerial parts and roots of Elionurus tristis were investigated by GC, GC-MS, pc-GC and NMR. Both aerial parts and roots EOs contained common molecules such as α-pinene, camphene, trans-α-bergamotene and calarene. Moreover, we identified several unusual sesquiterpenes and four undescribed compounds, 7-epi-khusian-2-...
Article
8-keto-10-dehydrobromo-γ-snyderol (1), a new sesquiterpene exhibiting the unusual γ-snyderane skeleton, was isolated from the ethyl acetate extract of Laurencia obtusa collected in Ajaccio (Corsica, France). (1) was isolated and fully characterized by detailed spectroscopic analysis. Six known compounds were identified after column chromatography s...
Article
Twenty‐three resin samples have been obtained by tapping from individual Pinus pinaster adult trees grown in Corsica and submitted to acido‐basic partition. Identification and quantitative determination of resin acids has been carried out using 13C‐NMR spectroscopy following a method developed by our group. The main components were dehydroabietic a...
Article
Full-text available
The chemical composition of 18 oil samples of Santolina africana isolated from aerial parts at full flowering, collected in three locations in eastern Algeria was determined by GC(RI), GC/MS and 13C-NMR analysis. The major components were: germacrene D, myrcene, spathulenol, α-bisabolol, β-pinene, 1,8-cineole, cis-chrysanthenol, capillene, santolin...
Article
Full-text available
Phytochemical investigations on bark of trunks and leaves of Diospyros soubreana (Ebenaceae) led to the isolation and characterization of nine molecules: one monocyclic sesquiterpenoid lactone (1), five pentacyclic triterpenes (2, 3, 4, 5 and 6), two sterols (7 and 8) and one carotenoid alcohol (9), all isolated for the first time from this species...