Fei Jiang

Shanghai Institute of Technology · School of Chemistry and Chemical Engineering

Replacing precious metals in oxygen evolution reaction (OER) catalysts has broad prospects to achieve a viable water splitting system. Since the electrocatalytic OER is a four-electron transfer reaction with a very sluggish kinetic process, there is great interest in the development of inexpensive, durable, and high-efficiency OER catalysts. Herein...

Perfluorooctanesulfonate acid (PFOS) is a typical persistent organic pollutant that widely exists in the environment. To clarify the toxic effects and mechanisms of PFOS and to find effective intervention strategies have been attracted global attention. Here, we investigated the effects of PFOS on the male reproductive system and explored the poten...

Electrocatalytic water splitting is an emerging technology for the development of maintainable hydrogen energy. It remains challenging to manufacture a stable, efficient, and cost-effective electrocatalyst that can conquer the slow reaction kinetics of water electrolysis. Herein, A metal-organic framework (MOF) based material is manufactured and pr...

For energy conversion and storage, the electrochemical oxygen evolution process (OER) is the crucial half-reaction process. The amphiprotic characteristics of sulfamic acid are due to its amine and sulphonic acid functional groups. Metal-based catalysts can be utilized to fabricate bimetallic and dual-ligand linked FeCo-SA/DABCO nanosheets with imp...

The development of low-cost, high-performance, and stable non-noble metal electrocatalysts for oxygen evolution reaction (OER) applications are crucial for future energy supply. Here, we designed ferrocene-based bimetallic CoFe-FcDA MOF nanosheets to realize high-efficient OER electrocatalysts. The resultant CoFe-FcDA nanosheets exhibited remarkabl...

The preparation of stable electrocatalyst for oxygen evolution reaction is of the utmost importance to realize high performance water decomposition reaction. Metal-organic framework (MOF) nanostructures have become promising materials. Herein, we report three kinds of electrocatalysts with different structures and properties for the oxygen evolutio...

Although reasonably specified and adjustable preparation of nanostructures with specific morphologies, ordered chemical compositions and electronic structures involving advanced energy chemistries is an important research area, high-efficiency, stable, and low-cost electrocatalysts for water splitting are greatly desirable and challenging. In this...

Reasonable design and synthesis of hetero atom metal coordination compounds on the atomic scale can significantly improve the performance of the catalysts. Herein, Pt/C (20%) is doped and inserted into the CoSSeNi catalyst through two steps of hydrothermal reaction and high temperature calcination process. Compared with the single metal Pt/C doped...

Among cases of SARS-CoV-2 infections that result in serious conditions or death, many have pre-existing conditions such as hypertension and are on renin–angiotensin–aldosterone system (RAAS) inhibitors. The angiotensin-converting-enzyme-2 (ACE2), a key protein of the RAAS pathway, also mediates cellular entry of SARS-CoV-2. RAAS inhibitors might af...

Objective Insomnia is a highly prevalent and disturbing symptom in breast cancer patients under or post chemotherapy. If not appropriately treated, it can persist for years after the completion of cancer treatments. Acupuncture has been widely used for alleviating insomnia. The aim of this study is to examine the feasibility, efficacy and safety of...

Long noncoding RNAs (lncRNAs) were identified rapidly due to their important role in many biological processes and human diseases including cancer. 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3] and its analogues are widely applied as preventative and therapeutic anticancer agents. However, the expression profile of lncRNAs regulated by 1α,25(OH)2D3 in o...

A series of covalent triazine frameworks (CTFs) are prepared via ionothermal synthesis for supercapacitors. Due to the feature of adjustable pore structure and rich nitrogen, CTFs with regular structure can be used as a group of model compounds to further investigate the influence of pore size and heteroatom on supercapacitors. By comparing the per...

Multiferrocenyl and multiadamantyl cuboctahedron nanospheres were synthesized via rapid self-assembly reactions of twelve 90° PdII-containing compounds and twenty-four 120° organic bidentate N-ligands in acetone solution. The selected self-assembly reaction and corresponding solvent were demonstrated to be effective and simple in the preparation of...

Herein, the design and manufacture of electrocatalysts based on bimetallic CoNiSSe-g-C3N4 and monometallic CoSSe-g-C3N4 are reported. A comparative research of electron transfer from bimetallic Co/Ni and monometallic Co active sites to a large amount of pyridine-N in the potential g-C3N4 to promote oxygen evolution reactions. The CoNiSSe-g-C3N4 hyb...

Active neurons impact cell types with which they are functionally connected. Both activity and functional connectivity are heterogeneous across the brain, but the nature of their relationship is not known. Here we employ brain-wide calcium imaging at cellular resolution in larval zebrafish to record spontaneous activity of >12,000 neurons in the fo...

BACKGROUND: Acupuncture has been an alternative approach for pain management, but trial evidence is conflicting. METHODS: 86 KOA patients were randomly assigned in a 1:1 ratio from June 14, 2017 to January 20, 2019, to receive either superficial needling acupuncture treatment or sham acupuncture for 10 sessions over a 4-week treatment period, foll...

Motivated by the wind turbine anomaly detection, we propose a Bayesian hierarchical model (BHM) for the mean-change detection in multivariate sequences. By combining the exchange random order distribution induced from the Poisson–Dirichlet process and nonlocal priors, BHM exhibits satisfactory performance for mean-shift detection with multivariate...

Background: Cancer is the second leading cause of death before the age of 70. Improved cancer survival has put increasing demands on cancer care. Palliative care is the specialized multi-disciplinary care providing relief from the pain, symptoms, and stress of serious illness. The study aims to evaluate the adjunctive effect of acupuncture for adva...

Dynamic resting state functional connectivity (RSFC) characterizes fluctuations that occurs over time in functional brain networks. Existing methods to extract dynamic RSFCs, such as sliding-window and clustering methods, have various limitations due to their inherent non-adaptive nature and high-dimensionality including an inability to reconstruct...

An octahedral nanosized M6L4 cage complex is assembled from six 90° Pd(II) compounds [Pd(phen)(NO3)2, phen=1,10-phenanthroline)] and four 120° trident ligands [2,4,6-tri(4-pyridyl)-1,3,5-triazine]. The size of the cage complex is verified by TEM image and electronic structure calculation. The cage complex can act as a host container that allows the...

Designing a low–cost, large–scale and highly–active electrolytic oxygen evolution catalyst is still a huge challenge. Pure stoichiometric NiO is inevitably an insulator, which hampers the electron transfer and transport in catalysis. While non-stoichiometric NiOx is a wide bandgap p-type semiconductor. The conductive interface of non-stoichiometric...

Objectives To establish a new ambulatory blood pressure (ABP) parameter (24-hour ABP profile) and evaluated its performance on stroke outcome in ischaemic stroke (IS) or transient ischaemic attack (TIA) patients. Methods The prospective cohort consisted of 1996 IS/TIA patients enrolled for ABP monitoring and a 3-month follow-up for stroke recurren...

Chemo-resistance to conventional therapy is a major barrier requiring further investigation in hepatocellular carcinoma (HCC). Cancer stem like cells (CSCs) contribute to the tumorigenicity, progression, and chemo-resistance of malignancies. Studies have implicated the anti-cancer effects of arsenic trioxide (ATO) and have explored the underlying m...

Background In order to complete the physiological function of postovulatory repair during repeated ovulation, the ovarian surface epithelium (OSE) not only has to undergo epithelial-mesenchymal transition (EMT), but also possess the properties of somatic stem-like cells. However, there is no evidence to indicate that both EMT alteration and stemnes...

IgA plays an important role in mucosal immunity against infectious pathogens, however, the molecular mechanism of IgA secretion in response to infection remains largely unknown, particularly in Mycoplasma . In this study, we found that the levels of IgA in the peripheral blood serum, bronchoalveolar lavage fluid, nasal mucosa, trachea, hilar lymph...

Background In order to complete the physiological function of postovulatory repair during repeated ovulation, the ovarian surface epithelium (OSE) not only has to undergo epithelial-mesenchymal transition (EMT), but also possess the properties of somatic stem-like cells. However, there is no evidence to indicate that both EMT alteration and stemnes...

We propose a Bayesian model selection (BMS) boundary detection procedure using non-local prior distributions for a sequence of data with multiple systematic mean changes. By using the non-local priors in the BMS framework, the BMS method can effectively suppress the non-boundary spike points with large instantaneous changes. Further, we speedup the...

The metabolic inhibition is a classic test for the identification of mycoplasma, used for measuring the growth-inhibiting antibody directed against acid-producing mycoplasma, although their mechanism still remains obscure. To determine the major antigens involved in the immune killing of Mycoplasma bovis , we used a pull-down assay with anti- M. bo...

Breast cancer (BC) is the most common female malignancy in the world. Triple-negative breast cancer (TNBC) is a subtype of BC characterized by the lack of estrogen receptors, progesterone receptors, and human epidermal growth factor receptor-2 (HER-2), resulting in the limited therapeutic options. Due to the aggressive behaviors at early stage, TNB...

Nucleases are ubiquitously recognized as essential proteins in mycoplasmas because these organisms lack most capacities for de novo synthesis of nucleotides. Some of these proteins were proved to be important pathogenic factors during the infection of mycoplasms. In this study, the protein Mhp597 from M. hyopneumoniae was expressed and purified in...

Lipid accumulation is a vital event in the progression of diabetic nephropathy. 1,25‐Dihydroxyvitamin D3 (1α,25(OH)2D3) is considered to have a protective effect on diabetic nephropathy. However, it remains unclear whether 1α,25(OH)2D3 can inhibit lipid accumulation, and the potential mechanisms responsible for lipid metabolism are incompletely und...

We propose a functional censored quantile regression model to describe the time-varying relationship between time-to-event outcomes and corresponding functional covariates. The time-varying effect is modeled as an unspecified function that is approximated via B-splines. A generalized approximate cross-validation method is developed to select the nu...

Wind power, as an alternative to burning fossil fuels, is plentiful and renewable. Data-driven approaches are increasingly popular for inspecting the wind turbine failures. In this paper, we propose a novel classification-based anomaly detection system for icing detection of the wind turbine blades. We effectively combine the deep neural networks a...

Covariate balance among different treatment arms is critical in clinical trials, as confounding effects can be effectively eliminated when patients in different arms are alike. To balance the prognostic factors across different arms, we propose a new dynamic scheme for patient allocation. Our approach does not require discretizing continuous covari...

We introduce a Bayesian defect detector to facilitate the defect detection on the motion blurred images on rough texture surfaces. To enhance the accuracy of Bayesian detection on removing non-defect pixels, we develop a class of reflected non-local prior distributions, which is constructed by using the mode of a distribution to subtract its densit...

PurposeData from National Health and Nutrition Examination Survey (NHANES) for the years 2007–2012 were used to evaluate the interactions of cadmium (Cd) exposure with being overweight/obesity on the risk of prediabetes among adults 20 years older. MethodsA total of 3552 subjects were included in the analysis. Urinary cadmium levels (UCd) was used...

A fluorescent and surface-enhanced Raman spectroscopy (SERS) dual-mode probe is developed for imaging of intracellular Zn²⁺ based on N-(2-(bis(pyridine-2-ylmethyl)amino)ethyl)-2-mercaptoacetamide (MDPA) modified gold nanoparticles (MDPA-GNPs). Benefiting from the chelation-enhanced fluorescence (CHEF) between MDPA-GNPs and Zn²⁺, the fluorescent int...

Background: Sinew acupuncture is a new modality of acupuncture in which needles are inserted into acupoints, ashi points or spasm points of sinew and muscles along the meridian sinew pathway. A previous observational study revealed that sinew acupuncture has immediate analgesic effects on various soft tissue injuries, including knee injuries. Howe...

Nonparametric estimation of the probability density function of a random variable measured with error is considered to be a difficult problem, in the sense that depending on the measurement error prop- erty, the estimation rate can be as slow as the logarithm of the sample size. Likewise, nonparametric estimation of the regression function with err...

MGA_0676 has been characterized as a Mycoplasma gallisepticum nuclease that can induce apoptosis of chicken cells. However, the mechanism by which MGA_0676 induces apoptosis has remained unclear. In this study, we evaluated MGA_0676-induced apoptosis and internalization in immortalized chicken embryo fibroblasts (DF-1) and cancer cell lines. The in...

[This corrects the article DOI: 10.1371/journal.pone.0161170.].

Wheat (Triticum aestivum L.) is one of the most productive and important crops and its yield potential and quality characteristics are tightly linked with the global food security. In this study, genome-wide association study (GWAS) was conducted for yield and quality-related traits. Based on the high-density wheat 90K Illumina iSelect SNP Array, 1...

Pulmonary fibrosis is a progressive fibrotic lung disease of persisting lung injury and ineffective wound repair, with poor prognosis. Epithelial-mesenchymal transition (EMT) of alveolar epithelia cells is an early event in the development of pulmonary fibrosis, and transforming growth factor β (TGF-β) is an acknowledged inducer of EMT. Epidemiolog...

Background Proton stress and aluminum (Al) toxicity are major constraints limiting crop growth and yields on acid soils (pH < 5). In Arabidopsis, STOP1 is a master transcription factor that controls the expression of a set of well-characterized Al tolerance genes and unknown processes involved in low pH resistance. As a result, loss-of-function sto...

Artificial intelligence (AI) aims to mimic human cognitive functions. It is bringing a paradigm shift to healthcare, powered by increasing availability of healthcare data and rapid progress of analytics techniques. We survey the current status of AI applications in healthcare and discuss its future. AI can be applied to various types of healthcare...

Colonizing bacteria interacting with the immature, unlike the mature, human intestine favors inflammation over immune homeostasis. As a result, ten percent of premature infants under 1500 grams weight develop an inflammatory necrosis of the intestine after birth, e.g., necrotizing enterocolitis (NEC). NEC is a major health problem in this populatio...

Individual data points used to build all the figures. (PDF)

Mycoplasma ovipneumoniae (MO) is main responsible for pleuropneumonia in sheep. The disease is spreading in the world, and has caused great suffering and losses to the sheep husbandry. Current methodologies for detecting and identifying MO are somehow time consuming, complicated, expensive. Herein, a powerful biosensing platform for effective MO de...

Lemnaceae (commonly called duckweed) is an aquatic plant ideal for quantitative analysis in plant sciences. Several species of this family represent the smallest and fastest growing flowering plants. Different ecotypes of the same species vary in their biochemical and physiological properties. Thus, selecting of desirable ecotypes of a species is v...

Aluminum (Al) toxicity inhibits root growth and limits crop yields on acid soils worldwide. However, quantitative information is scarce on protein expression profiles under Al stress in crops. In this study, we report on the identification of potential Al responsive proteins from root tips of Al sensitive BR007 and Al tolerant SC566 sorghum lines u...

Proteome profiling.

Differentially expressed proteins (fold changes) in 3D BR007.

Differentially expressed proteins (fold changes) in 5D BR007.

Differentially expressed proteins (fold changes) in 3D SC566.

Relative protein expression (fold changes) of antioxidant enzymes in BR007 and SC566 under Al treatment.

Key differentially expressed proteins in metabolism of xenobiotics by cytochrome P450 involved in Al tolerance.

Differentially expressed proteins (fold changes) in 5D SC566.

Key metabolic pathways for key proteins involved in Al tolerance. A total of nine peroxidases with >1.5-fold upregulation were found in the phenylpropanoid biosynthesis pathway in BR007 5D.

97 ecotypes of duckweed were collected and most of them were from China. The ecotypes from Zhao's lab were recorded its location, GPS information and altitude. Meanwhile, the haplotypes of these ecotypes were also presented.

Gastric carcinoma (GC) is the second leading cause of cancer-related mortality worldwide. The efficacy of standard chemotherapy for GC, such as cisplatin (CDDP), is dissatisfactory partly due to the toxic/side-effects. Sulforaphane (SFN), which exhibits effective anti-cancer functions, is a phytochemical converted from cruciferous plants. Our prese...

Nanosized anode materials have been shown to be successful in addressing the problems of metal oxide anodes during electrochemical reactions. However, issues with low Coulombic efficiencies and poor cyclability of nanostructured metal oxide anodes still need to be resolved. Ultrafine CuCo2O4 nanoparticles of 6∼9 nm uniformly anchored on graphene ha...

Motivated by the recent acquired immune deficiency syndrome clinical trial study A5175, we propose a semiparametric framework to describe time-to-event data, where only the dependence of the mean and variance of the time on the covariates are specified through a restricted moment model. We use a second-order semiparametric efficient score combined...

Chronic non-progressive pneumonia, a disease that has become a worldwide epidemic has caused considerable loss to sheep industry. Mycoplasma ovipneumoniae (M. ovipneumoniae) is the causative agent of interstitial pneumonia in sheep, goat and bighorn. We here have identified by immunogold and immunoblotting that elongation factor Tu (EF-Tu) and heat...

Amplification of EF-Tu and HSP70 gene of M. ovipneumoniae by overlap extension PCR and construction of the pET-28a (+)-EF-Tu and pET-28a (+)-HSP70 plasmids. (A) Extension PCR of the first round. Overlap extension PCR was used to mutate the A of UGA into G in the gene sequence of EF-Tu and HSP70 genes from M. ovipneumoniae for normal expression of t...

Immunoreactivity analysis of M. ovipneumoinae EF-Tu and HSP70. Whole-cell proteins of M. ovipneumoinae strain Y98 (lane 1), M. ovipneumoinae wild strain Mo-1 (lane 2), M. Arginini (lane 3), M. hyopneumoniae (lane 4), M. mycoides subsp. capri (lane 5), M. mycoides subsp. capri LC (lane 6), M. capricolum subsp. capricolum (lane 7), M. agalactiae (lan...

Background & aims: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. The continued search for novel therapeutic strategies for HCC is urgently required. In this study, we aimed to investigate the functions and clinical significance of 14-3-3η protein in HCC. Methods: Expressions of genes and proteins were determine...

A facile approach is designed to prepare novel conjugated polycarbazole microporous network P-Tetra (4-(N-carbazolyl)phenyl)silane (P-TCzPhSi) with tetra-substituted silicon center by FeCl3 oxidative coupling polymerization. The adsorption isotherm of N2 reveals that the polymer features a high Brunauer-Emmett-Teller (BET) specific surface area up...

A three-dimensional CoFe2O4 nanowire array on carbon cloth was fabricated with a hydrothermal method together with a post-annealing treatment. As a binder-free and flexible anode material for LIBs, it showed an improved electrochemical performance with high cycling stability and excellent rate capability. It exhibited an initial discharge capacity...