Fehmi Ates

Mersin University · Department of Internal Medicine

Background and Objectives: It has been demonstrated that parameters such as the Controlled Nutrition Status (CONUT) score and Prognostic Nutrition Index (PNI) are beneficial for the assessment of patients’ nutrition. In this study, our objective was to investigate the potential benefits of CONUT and, as a prognostic marker of acute pancreatitis, th...

Z GİRİŞ ve AMAÇ: Üst gastrointestinal sistem endoskopilerinde mide polibi saptadığımız hastaların demografik verileri ve poliplerin özelliklerini değerlendirmek. YÖNTEM ve GEREÇLER: Geriye dönük olarak, 2014-2018 yılları arasında hastanemiz Gastroenteroloji bilim dalında, üst gis endoskopilerinde mide polibi saptadığımız hastalar veri kayıt sistemi...

Objective: CAV1 encodes caveolin-1, a major protein of plasma membrane microdomains called caveolae, involved in several signalling pathways. Caveolin-1 is also located at the adipocyte lipid droplet. Heterozygous pathogenic variants of CAV1 induce rare heterogeneous disorders including pulmonary arterial hypertension and neonatal progeroid syndro...

Introduction:Colon polyps are proliferative and neoplastic lesions which originate from the mucosa, submucosa and protrude into the lumen. With this study, we aimed to reveal the demographic data, histopathological features, malignant potential and characteristics of patients with colonic polyp in our region by evaluating the results of 4-year colo...

Giriş ve Amaç Anemilerin çoğu gibi demir eksikliği anemisi de kendi başına bir hastalık değildir ve etyolojinin her hastada araştırılıp ortaya konması gerekmektedir. Demir eksikliği anemisi yaş gruplarına göre etyolojik nedenlerin sıklığı değişmektedir. Demir eksikliği anemisinin en önemli sebebi premenapozal kadınlarda menstrüel kanamalar iken; po...

Aim:Percutaneous endoscopic gastrostomy (PEG) is a method that can be applied for nutritional purposes in patients who cannot be fed orally for various reasons but whose gastrointestinal system functions are normal. In this study, we aimed to determine the etiological causes and long-term outcomes (efficacy, safety, lifespan) of PEG in patients ove...

Giriş ve Amaç Gastrointestinal (Gİ) stentler gastrointestinal kanaldaki malign veya benign darlıklarda ve akciğer kanseri gibi komşu organ maligniteleri ile ilişkili bası veya fistüllerde ya da operasyonlardan sonraki darlık veya kaçaklarda palyatif amaçla kullanılmaktadır. Biz kliniğimizde taktığımız Gİ stentlerin takılma nedenlerini ve seyrini de...

ZET Amaç: Ülkemizde yabani mantarların bilinçsizce gıda olarak tüketilmesi ve zehirli mantar türlerinin zehirsiz türlerden ayrılamamasından dolayı mantar zehirlenmeleri görülmektedir. Bu çalışmada, hastanemize başvurmuş mantar zehirlenmesi vakalarının demografik ve klinik verilerini, hastanede yatış süreleri ile ciddi komplikasyonları ve mortalitey...

Giriş ve Amaç: Kolorektal kanserlerin erken evrede belirlenmesi, prognozun iyileştirilmesindeki en önemli kısımdır. Bunun yolu etkili tarama programlarından geçmektedir. Gaitada gizli kan (GGK) testi tarama yöntemlerinin başında gelmektedir. Bu çalışmada endoskopi ünitemizde GGK testi pozitifliği nedeniyle kolonoskopi yapılan hastalarda kolonoskopi...

Anatomic alterations due to the hepatobiliary system pathologies such as stenosis, dilatation, stone, and tumor can be suspected by clinical symptoms, laboratory tests and eventually confirmed by imaging methods. Both Magnetic Resonance Colangiopathy (MRCP) and Endoscopic Ultrasonography (EUS) are diagnostic tools for etiologic assessment of extra...

Background/aims: In previous studies that investigated the impact of direct-acting antiviral (DAA) treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients have been compared to baseline values with either end of treatment or post-treatment values. The results are inconsistent. We evaluated patients throughout the treat...

Aim:Swallowing foreign bodies is a common clinical problem. Especially sharp and pointed objects can cause life-threatening complications such as obstruction, gastrointestinal (GI) bleeding or intestinal perforation. In this article, we aimed to report our experience and results of patients who underwent endoscopy in our clinic due to foreign body...

Gaucher hastalığı hepatosplenomegaliye neden olabilen bir lipid depo hastalığıdır. Zamanında tanı konamayan hastalarda ciddi splenomegaliye neden olabilmekte ve tanı alamamış hastalar gereksiz splenektomiye gidebilmektedir. Bu amaçla splenektomi yapılmış hastalar arasında zamanında tanısı konamamış, ancak splenektomi sonrası Gaucher hastalığı tanıs...

Hepatitis C virus is one of the leading causes of liver cirrhosis and hepatocellular carcinoma. The tumor-associated calcium signal transducer 2 (Tacstd-2) molecule is thought to be involved in the expression of a number of molecules that facilitate transport of hepatitis C into the cell. The aim of this study was to investigate Tacstd-2 concentrat...

Introduction:Caustic substance ingestion is a serious problem due to high morbidity and mortality. Chemical products used in homes are the source of accidental or deliberate caustic exposures that can be seen in people of different ages. The severity of the lesions produced by the caustic substances in the tissue depends on the type, amount and con...

Aim: We demonstrated a decade ago that standard triple therapy was unsuccessful in Helicobacter pylori (H.pylori) eradication in our region. Unfortunately, the eradication studies we have done with different therapy charts so far have proved insufficient as well. Thus, we aimed to compare combinations containing rifaximin with or without N-acetyl c...

Background and study aims: The role of oxidative stress in inflammatory bowel disease is increasingly recognised as an important factor. It is assumed that reduced levels of paraoxonase-1 (PON-1) and arylesterase (ARE) may lead to increased inflammation due to increased oxidative stress. This study aimed to investigate the relationship between ARE...

the role of leptin and leptin receptor gene polymorphisms in patients with Irritable Bowel Syndrome in Turkish populations

Background: Irritable bowel syndrome(IBS) is a gastrointestinal(GI) system disease that is characterized by altered bowel habits and abdominal pain in the absence of detectable structural abnormalities. Familial aggregation and twin studies suggest that there is a genetic contribution to the development of disease. Leptin and its receptors expresse...

Background/aims: As the most common liver disease in hemodialysis patients, chronic hepatitis C (CHC) can cause cirrhosis and hepatocellular carcinoma, even increase in renal-related mortality. In Turkey, the frequency of anti-hepatitis C virus (HCV) antibodies in hemodialysis patients ranged from 31.4% to 51%. Until recently, the mainstay of the...

Aim Percutaneous needle liver biopsy (PLB) is frequently associated with pain and anxiety. This may discourage the patients for biopsy, and rebiopsies, if needed. We planned a study to investigate the efficacy of additional analgesia or sedation for PLB. Materials and methods The study has been designed as a single-center, prospective study. The P...

Objectives/study design: Current diagnostic tests for gastroesophageal reflux disease (GERD) do not consistently measure chronicity of reflux. Mucosal impedance (MI) is a minimally invasive measurement to assess esophageal conductivity changes due to GERD. We aimed to investigate MI pattern in patients with symptoms of extraesophageal reflux (EER)...

Background & aims: Although chronic cough is common, its etiology is often elusive, making patient management a challenge. Gastroesophageal reflux and airway hypersensitivity can cause chronic cough. We explored the relationship between reflux, phonation, and cough in patients with idiopathic chronic cough. Methods: We performed a blinded, cross...

The role of esophageal dilation in patients with esophageal eosinophilia with dysphagia remains unknown. The practice of dilation is currently based on center preferences and expert opinion. The aim of this study is to determine if, and to what extent, dysphagia improves in response to initial esophageal dilation followed by standard medical therap...

Achalasia is an esophageal motility disorder that is commonly misdiagnosed initially as gastroesophageal reflux disease. Patients with achalasia often complain of dysphagia with solids and liquids but may focus on regurgitation as the primary symptom, leading to initial misdiagnosis. Diagnostic tests for achalasia include esophageal motility testin...

Öz • en • tr Rectal varices are a rare cause of lower gastrointestinal bleeding. Congenital or familial venous anomalies, portal hypertension, heart failure, and venous thrombosis are predisposing factors, and in a small proportion of patients, the etiology is unknown. This case is presented here in order to highlight the fact that rectal varices...

Gastroesophageal reflux disease (GERD) is a common condition that presents with symptoms of heartburn and regurgitation. Asthma is an equally common medical condition that often coexists with GERD. The clinical scenario of difficult-to-treat asthma in the setting of concomitant GERD leads to the possibility of GERD-induced asthma. However, asthma m...

Current diagnostic tests for gastroesophageal reflux disease (GERD) are suboptimal and do not accurately and reliably measure chronicity of reflux. A minimally invasive device has been developed to assess esophageal mucosal impedance (MI) as a marker of chronic reflux. We performed a prospective longitudinal study to investigate patterns of MI in pa...

'Refractory gastroesophageal reflux disease' is one of the most common misnomers in the area of gastroesophageal reflux disease. The term implies reflux as the underlying etiology despite unresponsiveness to aggressive proton pump inhibitor therapy. The term should be replaced with 'refractory symptoms.' We must acknowledge that in many patients sy...

Opinion statement: "Refractory GERD" is one the most common misnomers in the area of gastroesophageal reflux disease. The term implies reflux as the underlying etiology despite unresponsiveness to aggressive, often twice-daily proton pump inhibitor therapy. The term should be replaced with "refractory symptoms." We must acknowledge that in many pa...

Reflux related cough, asthma and laryngitis are frequently encountered and are considered part of extraoesophageal syndromes. The diagnosis of extraoesophageal reflux is difficult due to the lack of gold standard diagnostic criteria. Esophagogastroduodenoscopy and esophageal pH monitoring are inadequate diagnostic tools for due to poor sensitivity...

Aortic dissection is one of the leading life threatening cardiovascular emergencies. In this clinical entity, following the intimal tear, blood forms a channel splitting the inner and outer sheets of the medial layer. Pushing forward through the medial layer, the blood detaches the intimae from the adventitial layer. There can be complications such...

Reflux related cough, asthma and laryngitis are frequently encountered and are considered part of extraoesophageal syndromes. The diagnosis of extraoesophageal reflux is difficult due to the lack of gold standard diagnostic criteria. Esophagogastroduodenoscopy and esophageal pH monitoring are inadequate diagnostic tools for due to poor sensitivity...

To evaluate the impact of liver steatosis upon response to given therapy in chronic hepatitis B (CHB) patients. 84 consecutive CHB patients treated with 48-wk PEGylated interferon (PEG-IFN) therapy were enrolled. Baseline characteristics and sustained viral response (SVR) to PEG-IFN therapy were evaluated. Mean body mass index (BMI) was 27.36 ± 4.4...

We aimed to determine the changes in the pulmonary function tests of the patients with inflammatory bowel diseases. Forty inflammatory bowel dieases patients; 30 ulcerative colitis and 10 Crohn's disease, and ageand sex-matched control group, consisting of 30 healthy persons, were included in the study. Disease activity in patients with ulcerative...

Much is known about the gastric tissue damage that is associated with hypovolemic stress, but gastrointestinal bleeding due to gastric injury and further gastric injury due to hypovolemia have not been evaluated in previous research. The aim of this study was to assess oxidative gastric tissue damage specifically linked to hypovolemia in patients w...

The aim of the present case-control study was to determine whether or not the prevalence of gallbladder stones (GBS) was increased in patients with chronic myelocytic leukemia (CML) and to investigate clinical and laboratory characteristics of CML patients with GBS. This study included 56 patients with CML and 55 sex- and age-matched healthy contro...

Acute pancreatitis is a serious complication of organophosphate poisoning. There is no report in the literature dealing with the development of a pancreatic pseudocyst after complication of organophosphate-induced acute pancreatitis. Therefore, we present a case who developed pancreatic pseudocyst after complication of organophosphate-induced acute...

In previous studies, it has been shown that QT interval prolongation is related to an increased mortality rate in chronic liver disease (CLD). But QT dispersion (QTd) and its clinical significance in CLD has not been well studied. The objectives of this study were to investigate the relation between QTd and severity of the disease and determine its...

Many studies have demonstrated that cirrhosis is frequently associated with autonomic dysfunction. The aim of this study was to test autonomic dysfunction in cirrhotic patients by analyzing heart rate variability (HRV), to determine whether or not the degree of autonomic dysfunction is correlated with the severity of disease, and, also, to compare...

Bacterial translocation (BT) has been implicated in the development of infectious complications in many serious clinical conditions such as fulminant hepatic failure (FHF). We aimed to investigate the effects of Gingko biloba (GB), vitamin E (Vit E) and melatonin on intestinal oxidative damage and BT in thioacetamide (TAA)-induced FHF in rats. A to...

The aim of the present study was to investigate changes in pulmonary function tests (PFTs) in patients with acute pancreatitis (AP), to compare them with those changes in healthy controls, and to analyze the relationship between these parameters and computed tomography severity index (CTSI) and Ranson's criteria scores as markers of disease severit...

It has been previously proposed that electrocardiographic abnormalities may be associated with acute pancreatitis. However, there is a lack of data on the QT interval and dispersion value in patients with acute pancreatitis, and no data are also available concerning QT interval and QT dispersion in acute biliary pancreatitis (ABP). : We aimed to in...

Psychiatric disorders have been considered in terms of non-compliant behaviour and low life quality in haemodialysis patients. The aim of this study is to investigate the potential association of psychiatric disorders with compliance of fluid restriction and nutritional status and to measure the effects of psychiatric disorders on the life quality...

Bismuth subcitrate is a known nephrotoxic agent that may lead to acute oliguric renal failure when ingested in toxic doses. We report a 17-year-old girl who was admitted to the emergency room with complaints of nausea, vomiting, and anuria. She had taken 25 tablets containing 300 mg bismuth subcitrate (total 7.5 g). The patient was managed with hem...

Bismuth subcitrate is a known nephrotoxic agent that may lead to acute oliguric renal failure when ingested in toxic doses. We report a 17-year-old girl who was admitted to the emergency room with complaints of nausea, vomiting, and anuria. She had taken 25 tablets containing 300 mg bismuth subcitrate (total 7.5 g). The patient was managed with hem...