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69
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Introduction
Federico's research interests span image processing, algorithms and optimization, and medical imaging. His contributions include the optimization of binary image processing algorithms, introducing innovative approaches that deliver significant performance improvements on both CPU and GPU architectures. His work also encompasses advanced techniques for skin lesion segmentation and classification, segmentation of maxillofacial structures in CBCT scans, and whole-slide image analysis.
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Publications
Publications (69)
In recent years, several algorithms have been developed for the segmentation of the Inferior Alveolar Canal (IAC) in Cone-Beam Computed Tomography (CBCT) scans. However, the availability of public datasets in this domain is limited, resulting in a lack of comparative evaluation studies on a common benchmark. To address this scientific gap and encou...
Overcrowding in Emergency Departments (EDs) is a pressing concern driven by high patient demand and limited resources. Prolonged Length of Stay (pLOS), a major contributor to this congestion, may lead to adverse outcomes, including patients leaving without being seen, suboptimal clinical care, increased mortality rates, provider burnout, and escala...
Objectives
The shape is commonly used to describe the objects. State-of-the-art algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and implicit surface models are used. This is seen from the growing popularity of ShapeNet (51,300 models) and Princeton ModelNet (127,915 models). H...
Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical practice. In this work, we organized the first international competition dedicated to promptable medical image...
Recently, the field of 3D medical segmentation has been dominated by deep learning models employing Convolutional Neural Networks (CNNs) and Transformer-based architectures, each with their distinctive strengths and limitations. CNNs are constrained by a local receptive field, whereas transformers are hindered by their substantial memory requiremen...
Segmentation of the Inferior Alveolar Canal (IAC) is a critical aspect of dentistry and maxillofacial imaging, garnering considerable attention in recent research endeavors. Deep learning techniques have shown promising results in this domain, yet their efficacy is still significantly hindered by the limited availability of 3D maxillofacial dataset...
This article is about Connected Components Labeling (CCL) algorithms developed for GPU accelerators. The task itself is employed in many modern image-processing pipelines and represents a fundamental step in different scenarios, whenever object recognition is required. For this reason, a strong effort in the development of many different proposals...
Introduction: Length of Stay (LOS) and Prolonged Length of Stay (pLOS) are critical indicators of hospital efficiency. Reducing pLOS is crucial for patient safety, autonomy, and bed allocation. This study investigates different machine learning (ML) models to predict LOS and pLOS.
Methods: We analyzed a dataset of patients discharged from a norther...
The usage of Multi Instance Learning (MIL) for classifying Whole Slide Images (WSIs) has recently increased. Due to their gigapixel size, the pixel-level annotation of such data is extremely expensive and time-consuming, practically unfeasible. For this reason, multiple automatic approaches have been raised in the last years to support clinical pra...
The adoption of Multi-Instance Learning (MIL) for classifying Whole-Slide Images (WSIs) has increased in recent years. Indeed, pixel-level annotation of gigapixel WSI is mostly unfeasible and time-consuming in practice. For this reason, MIL approaches have been profitably integrated with the most recent deep-learning solutions for WSI classificatio...
Histopathological image analysis is a critical area of research with the potential to aid pathologists in faster and more accurate diagnoses. However, Whole-Slide Images (WSIs) present challenges for deep learning frameworks due to their large size and lack of pixel-level annotations. Multi-Instance Learning (MIL) is a popular approach that can be...
The Inferior Alveolar Nerve (IAN) is of main interest in the maxillofacial field, as an accurate localization of such nerve reduces the risks of injury during surgical procedures. Although recent literature has focused on developing novel deep learning techniques to produce accurate segmentation masks of the canal containing the IAN, there are stil...
We present MedShapeNet, a large collection of anatomical shapes (e.g., bones, organs, vessels) and 3D surgical instrument models. Prior to the deep learning era, the broad application of statistical shape models (SSMs) in medical image analysis is evidence that shapes have been commonly used to describe medical data. Nowadays, however, state-of-the...
Whole-Slide Images (WSI) are emerging as a promising resource for studying biological tissues, demonstrating a great potential in aiding cancer diagnosis and improving patient treatment. However, the manual pixel-level annotation of WSIs is extremely time-consuming and practically unfeasible in real-world scenarios. Multi-Instance Learning (MIL) ha...
Histopathological image analysis is a critical area of research with the potential to aid pathologists in faster and more accurate diagnoses. However, Whole-Slide Images (WSIs) present challenges for deep learning frameworks due to their large size and lack of pixel-level annotations. Multi-Instance Learning (MIL) is a popular approach that can be...
The Inferior Alveolar Nerve (IAN) is of main interest in the maxillofacial field, as an accurate localization of such nerve reduces the risks of injury during surgical procedures. Although recent literature has focused on developing novel deep learning techniques to produce accurate segmentation masks of the canal containing the IAN, there are stil...
Featured Application
Convolutional neural networks can accurately identify the Inferior Alveolar Canal, rapidly generating precise 3D data. The datasets and source code used in this paper are publicly available, allowing the reproducibility of the experiments performed.
Abstract
Introduction: The need of accurate three-dimensional data of anatomic...
Connected Components Labeling (CCL) represents an essential part of many Image Processing and Computer Vision pipelines. Given its relevance on the field, it has been part of most cutting-edge Computer Vision libraries. In this paper, all the algorithms included in the OpenCV during the years are reviewed, from sequential to parallel/GPU-based impl...
Background and objectives:
Digital pathology and artificial intelligence offer new opportunities for automatic histologic scoring. We applied a deep learning approach to IgA nephropathy biopsy images to develop an automatic histologic prognostic score, assessed against ground truth (kidney failure) among patients with IgA nephropathy who were trea...
Several algorithmic solutions for the optimization of Connected Components Labeling have been proposed in literature. Among them, one of the most effective is a block-based mask to drastically reduce the number of memory accesses during the labeling procedure. This paper proposes a systematic approach for labeling multiple pixels at once, automatic...
At the present time, we are immersed in the convergence between Big Data, High-Performance Computing and Artificial Intelligence. Technological progress in these three areas has accelerated in recent years, forcing different players like software companies and stakeholders to move quickly. The European Union is dedicating a lot of resources to main...
Inferior Alveolar Nerve (IAN) canal detection has been the focus of multiple recent works in dentistry and maxillofacial imaging. Deep learning-based techniques have reached interesting results in this research field, although the small size of 3D maxillofacial datasets has strongly limited the performance of these algorithms. Researchers have been...
Connected Components Labeling (CCL) is a fundamental task in binary image processing. Since its introduction in the sixties, several algorithmic strategies have been proposed to optimize its execution time.
Most CCL algorithms in literature, including the current state-of-the-art, are designed to work on an input stored with 1-byte per pixel, even...
This paper provides a detailed description of how to install, setup, and use the YACCLAB benchmark to test the algorithms published in “A Heuristic-Based Decision Tree for Connected Components Labeling of 3D Volumes,” underlying how the parameters affect and influence experimental results.
Convolutional Neural Networks (CNNs) have been broadly employed in dermoscopic image analysis, mainly as a result of the large amount of data gathered by the International Skin Imaging Collaboration (ISIC). Like in many other medical imaging domains, state-of-the-art methods take advantage of architectures developed for other tasks, frequently assu...
In this paper, we present novel strategies for optimizing the performance of many binary image processing algorithms. These strategies are collected in an open-source framework, GRAPHGEN, that is able to automatically generate optimized C++ source code implementing the desired optimizations. Simply starting from a set of rules, the algorithms intro...
Background and objectives:
Immunohistopathology is an essential technique in the diagnostic workflow of a kidney biopsy. Deep learning is an effective tool in the elaboration of medical imaging. We wanted to evaluate the role of a convolutional neural network as a support tool for kidney immunofluorescence reporting.
Design, setting, participants...
This paper presents a novel strategy that employs Generative Adversarial Networks (GANs) to augment data in the skin lesion segmentation task, which is a fundamental first step in the automated melanoma detection process. The proposed framework generates both skin lesion images and their segmentation masks, making the data augmentation process extr...
The problem of labeling the connected components of a binary image is well defined, and several proposals have been presented in the past. Since an exact solution to the problem exists, algorithms mainly differ on their execution speed. In this paper, we propose and describe YACCLAB, Yet Another Connected Components Labeling Benchmark. Together wit...
![Fig. 4. Optimal DTree obtained using the algorithm presented in [24]...](profile/Federico-Bolelli/publication/336619534/figure/fig2/AS:837764765458432@1576750093264/Optimal-DTree-obtained-using-the-algorithm-presented-in-24-and-the-mask-of-Fig-1b_Q320.jpg)
Connected Components Labeling is an essential step of many Image Processing and Computer Vision tasks. Since the first proposal of a labeling algorithm, which dates back to the sixties, many approaches have optimized the computational load needed to label an image. In particular, the use of decision forests and state prediction have recently appear...
In this paper, we introduce a novel GPU-based Connected Components Labeling algorithm: the Block-based Union Find. The proposed strategy significantly improves an existing GPU algorithm, taking advantage of a block-based approach. Experimental results on real cases and synthetically generated datasets demonstrate the superiority of the new proposal...
In this paper we propose a strategy to optimize the performance of thinning algorithms. This solution is obtained by combining three proven strategies for binary images neighborhood exploration, namely modeling the problem with an optimal decision tree, reusing pixels from the previous step of the algorithm, and reducing the code footprint by means...
Connected Components Labeling (CCL) is a crucial step of several image processing and computer vision pipelines. Many efficient sequential strategies exist, among which one of the most effective is the use of a block-based mask to drastically cut the number of memory accesses. In the last decade, aided by the fast development of Graphics Processing...
In this paper the problem of Connected Components Labeling (CCL) in binary images using Graphic Processing Units (GPUs) is tackled by a different perspective. In the last decade, many novel algorithms have been released, specifically designed for GPUs. Because CCL literature concerning sequential algorithms is very rich, and includes many efficient...
This paper presents a novel strategy to perform skin lesion segmentation from dermoscopic images. We design an effective segmentation pipeline, and explore several pre-training methods to initialize the features extractor, highlighting how different procedures lead the Convolutional Neural Network (CNN) to focus on different features. An encoder-de...
In this paper we describe the algorithmic implementation details of “Connected Components Labeling on DRAGs” (Directed Rooted Acyclic Graphs), studying the influence of parameters on the results. Moreover, a detailed description of how to install, setup and use YACCLAB (Yet Another Connected Components LAbeling Benchmark) to test DRAG is provided.
In this paper the problem of Connected Components Labeling (CCL) in binary images using Graphic Processing Units (GPUs) is tackled by a different perspective. In the last decade, many novel algorithms have been released, specifically designed for GPUs. Because CCL literature concerning sequential algorithms is very rich, and includes many efficient...
This paper presents a novel strategy to perform skin lesion segmentation from dermoscopic images. We design an effective segmen-tation pipeline, and explore several pre-training methods to initialize the features extractor, highlighting how different procedures lead the Convolutional Neural Network (CNN) to focus on different features. An encoder-d...
Current movie captioning architectures are not capable of mentioning characters with their proper name, replacing them with a generic “someone” tag. The lack of movie description datasets with characters’ visual annotations surely plays a relevant role in this shortage. Recently, we proposed to extend the M-VAD dataset by introducing such informati...
Current movie captioning architectures are not capable of mentioning characters with their proper name, replacing them with a generic "someone" tag. The lack of movie description datasets with characters' visual annotations surely plays a relevant role in this shortage. Recently, we proposed to extend the M-VAD dataset by introducing such informati...
This paper proposes a novel strategy that employs Generative Adversarial Networks (GANs) to augment data in the image segmentation field, and a Convolutional-Deconvolutional Neural Network (CDNN) to automatically generate lesion segmentation mask from dermoscopic images. Training the CDNN with our GAN generated data effectively improves the state-o...
In this paper we introduce a new Connected Components Labeling (CCL) algorithm which exploits a novel approach to model decision problems as Directed Acyclic Graphs with a root, which will be called Directed Rooted Acyclic Graphs (DRAGs). This structure supports the use of sets of equivalent actions, as required by CCL, and optimally leverages thes...
This work presents a research project, named XDOCS, aimed at extending to a much wider audience the possibility to access a variety of historical documents published on the web. The paper presents an overview of the indexing process that will be used to achieve the goal, focusing on the adopted dewarping technique. The proposed dewarping approach p...
In this paper we present an innovative technique to semi-automatically index handwritten word images. The proposed method is based on HOG descriptors and exploits Dynamic Time Warping technique to compare feature vectors elaborated from single handwritten words. Our strategy is applied to a new challenging dataset extracted from Italian civil regis...
This paper presents two strategies that can be used to improve the speed of Connected Components Labeling algorithms. The first one operates on optimal decision trees considering image patterns occurrences, while the second one articulates how two scan algorithms can be parallelized using multi-threading. Experimental results demonstrate that the p...
In this paper we propose a new paradigm for connected components labeling, which employs a general approach to minimize the number of memory accesses, by exploiting the information provided by already seen pixels, removing the need to check them again. The scan phase of our proposed algorithm is ruled by a forest of decision trees connected into a...
