Fatma Ayaz

Selcuk University · Department of Pharmacognosy

The essential oils obtained from the aerial parts and the roots of Conyza canadensis (L.) Cronquist (Asteraceae) at the flowering stage, collected from Turkey were simultaneously analysed by GC-FID and GC-MS. Forty-six components comprising 82.8% of the essential oil from the aerial parts and seven components comprising 96.7% of the roots oil were...

The seed oils of twenty-six species of Apiaceae belonging to the genera Bunium, Cnidium, Ferula, Ferulago, Heracleum, Hippomarathrum, Malabaila, Myrrhoides, Olymposciadium, Pimpinella, Prangos, Szovitsia, Trigonasciadium, Trinia and Zosima, collected in Turkey, were investigated for their oil content, and amount of petroselinic acid (PA), as well a...

The composition of the hydrodistilled essential oils obtained from aerial parts of Grammosciadium schischkinii (V.M.Vinogr. & Tamamsch.) V.M.Vinogr., G. haussknechtii Boiss., G. pterocarpum Boiss. and G. platycarpum Boiss. & Hausskn. ex Boiss. (Apiaceae) which belong to subgenus Caropodium, growing in Turkey, were simultaneously analyzed by GC and...

Essential oils obtained by hydrodistillation from the aerial parts and fruits of five taxa of genus Grammosciadium DC., belonging to subgenus Grammosciadium (G. confertum Hub.-Mor. & Lamond, G. cornutum (Nábělek) C.C.Towns., G. macrodon Boiss. subsp. macrodon, G. macrodon Boiss. subsp. nezaketae B.Bani and G.daucoides DC. ), collected from differen...

The aim of this study was to investigate the antioxidant and enzyme inhibition activities of methanol extracts prepared from Klasea serratuloides (DC) Greuter & Wagenitz subsp. karamanica B. Dogan & A. Duran with Soxhlet, ultrasonic extraction, and maceration methods. 1,1-Diphenyl-2-picryl hydroxyl (DPPH) quenching assay and 2,2’-azinobis-3- ethylb...

Origanum haussknechtii Boiss. (Lamiaceae), an endemic herb growing in Turkey, is consumed as a tea in folk medicine. This study aimed to investigate antimicrobial, antibiofilm, and cytotoxic activities of the methanol, and water extracts from the aerial parts of O. haussknechtii, as well as to determine their phenolic profiles by using HPLC analysi...

Hesperis isatidea (Brassicaceae) is a perennial herbaceous endemic plant known as “Allıgelin”. It has traditional use concerning the cough, wound, cold and vulnerary in the form of decoction and poultice in Eastern Turkey. In this study, the in vitro antioxidant activity (DPPH, ABTS, FRAP, and metal chelating) and enzyme inhibitory activities (anti...

Three undescribed sesquiterpene lactones (1-3), 1β,4β-dihydroxy-guaia-10(14),11(13)-dien-8α,12-olide (1), 4α, 6α-dihydroxy-9β,10β-epoxy-1βH-guaia-11(13)-en-8α,12-olide (2), and 4α,9β-dihydroxy-6α-acetoxy-1βH-guaia-10(14),11(13)-dien-8α,12-olide (3), as well as a known sesquiterpene lactone, (4α,5α,8β,10α)-4,10-dihydroxy-1,11(13)-guaiadien-12,8-olid...

The aerial parts of Chrysophthalmum montanum (DC.) Boiss. (Asteraceae) is traditionally used for wound healing, as well as for the treatment of common cold, sinusitis, and other inflammatory diseases. The objectives of this study were to identify potential anti-inflammatory effects of the methanol extract, and its different polarity subextracts (n-...

The genus Sideritis L. (Lamiaceae) is mainly distributed in Mediterranean region and commonly known as “Dağ çayı, Yayla çayı, Alanya adaçayı and Balbaşı” in Turkey. Sideritis genus has long been used for their antiinflammatory, antiulcerogenic, antimicrobial, analgesic, digestive and wound healing properties in folk medicine. Amongst them, Sideriti...

Centaurea L. genus is represented by a large number of species, including Southwestern, central, and eastern Anatolia in our country. There are many studies on antioxidant, anti-inflammatory, antimicrobial, antipyretic, and wound healing activities of Centaurea species in the literature. In addition, phytochemical researches on the secondary metabo...

The genus Marrubium L., belonging to Lamiaceae family, is distributed in Europe, Asia, and Brazil as well as is represented by around 50 species. Marrubium vulgare L., which has traditional usage for many years, is used against dyspeptic diseases, loss of appetite and cough, as well as for wound healing, and choleretic. In this study, it was aimed...

Bioassay-guided isolation of the 80% methanol extract of the aerial parts of Chrysophthalmum montanum (DC.) Boiss. (Asteraceae) led to the isolation of four known guaianolide-type sesquiterpene lactones, 6α-acetoxy-4α-hydroxy-1βH-guaia-9.11(13)-dien-12.8α-olide (1), 6α-acetoxy-4α-hydroxy-9β.10β-epoxy-1βH-guaia-11(13)-en-12.8α-olide (2), 4α,6α-dihyd...

Objectives: The aim of this study was to investigate the probable toxicity on brine shrimp, phytotoxicity, and insecticidal activity of Chrysophthalmum gueneri Aytac & Anderb. Materials and Methods: The MeOH (80%) extract obtained from the whole plant of C. gueneri was fractionated through subsequent solvent extractions in increasing polarity with...

Background: Chrysophthalmum dichotomum Boiss. and Heldr. (Asteraceae) is an endemic herbaceous plant to Southern part of Turkey. Aim: To investigate in vitro phytotoxic, cytotoxic and insecticidal activities of C. dichotomum. Methods: The MeOH extract of C. dichotomum was fractionated through subsequent solvent extractions in increasing polarity wi...

Objectives: The aim of this study was to investigate the probable toxicity on brine shrimp, phytotoxicity, and insecticidal activity of Chrysophthalmum gueneri Aytac & Anderb. Materials and methods: The MeOH (80%) extract obtained from the whole plant of C. gueneri was fractionated through subsequent solvent extractions in increasing polarity wi...

Objectives: To investigate the in vitro cytotoxic, phytotoxic, and insecticidal activity of Chrysophthalmum montanum (DC.) Boiss. Materials and Methods: The crude methanol (80%) extract of the aerial parts of C. montanum was fractionated to obtain n-hexane, chloroform, n-butanol, and remaining water fractions. The crude extract and subsequent solve...

Chemical composition and antimicrobial activity of the hydrodistilled essential oils from aerial parts and roots of Aster subulatus Michx. (Asteraceae) from Turkey were investigated. The essential oils of A. subulatus were analyzed by combination of GC-FID and GC-MS. Twenty-nine components comprising 79.0% of the essential oil of the roots and fort...

Asteraceae family plants are receiving great attention because they have potential anticancer activity. Therefore, in this study, the cytotoxic effect of Conyza canadensis (L.) Cronquist (Asteraceae) were tested against human lung adenocarcinoma cell lines (A549 and H1299) for the first time. Cytotoxic effect of the n-hexane, chloroform, n-butanol...

Althaea officinalis L. (Malvaceae), commonly known as "hatmi", is native in our country. The roots "Althaeae radix" and the leaves "Althaeae folium" of the plants are registered as herbal drugs in European Pharmacopoeia. Regarding to the high mucilage amounts, the roots and leaves of the plants are used as antitussive agents. The aim of this study...