Fatima Sheikh

McMaster University | McMaster · Department of Health Research Methods, Evidence, and Impact

Background High-cost users (HCU) represent important targets for health policy interventions. Sepsis is a life-threatening syndrome that is associated with high morbidity, mortality, and economic costs to the healthcare system. We sought to estimate the effect of sepsis on being a subsequent HCU. Methods Using linked health-administrative database...

Synthetic biology is a growing field with an increasing number of successful applications. Yet, synthetic biology (SynBio) education initiatives are underreported and disconnected from each other. In this review we survey the literature on SynBio education and stratify this body of work into three categories: classroom activities, course designs, a...

Introduction Sociodemographic variables influence health outcomes, either directly (ie, gender identity) or indirectly (eg, structural/systemic racism based on ethnoracial group). Identification of how sociodemographic variables can impact the health of critically ill adults is important to guide care and research design for this population. Howeve...

We aimed to identify whether social determinants of health (SDoH) are associated with the development of sepsis and assess the differences between individuals living within systematically disadvantaged neighbourhoods compared with those living outside these neighbourhoods. We conducted a single-centre case-control study including 300 randomly selec...

Sepsis is a global health threat with significant morbidity and mortality. Despite clinical practice guidelines and developed health systems, sepsis is often unrecognized or misdiagnosed, leading to preventable harm. In Canada, sepsis is responsible for 1 in 20 deaths and is a significant driver of health system costs. Despite being a signatory to...

Background Sepsis, the life-threatening host response to infection, is a major cause of mortality. Obesity increases vulnerability to sepsis; however, some degree of obesity may be protective, called the “obesity paradox”. This scoping review systematically maps the literature on outcomes associated with diet-induced obesity and sepsis-induced orga...

Introduction To our knowledge, this study is the first to identify and describe current sepsis policies, clinical practice guidelines, and health professional training standards in Canada to inform evidence-based policy recommendations. Methods and analysis This study will be designed and reported according to the Arksey and O’Malley framework for...

The COVID-19 pandemic has had a global effect. The disproportionate impact on Indigenous peoples and racialized groups has brought ethical challenges to the forefront in research and clinical practice. In Canada, the Tri-Council Policy Statement (TCPS2), and specifically the principle of justice, emphasizes additional care for individuals “whose ci...

Introduction Accurate measurement of health status is essential to assess veterans’ needs and the effects of interventions directed at improving veterans’ well-being. We conducted a systematic review to identify instruments that measure subjective health status, considering four components (ie, physical, mental, social or spiritual well-being). Me...

Abstract Background Sepsis, the dysregulated host response to infection, triggers abnormal pro-coagulant and pro-inflammatory host responses. Limitations in early disease intervention highlight the need for effective diagnostic and prognostic biomarkers. Protein C’s role as an anticoagulant and anti-inflammatory molecule makes it an appealing targe...

OBJECTIVE:. Evaluating risk for sepsis is complicated due to limited understanding of how social determinants of health (SDoH) influence the occurence of the disease. This scoping review aims to identify gaps and summarize the existing literature on SDoH and the development of sepsis in adults. DATA SOURCES:. A literature search using key terms rel...

C102 USING ANALOG OR TECHNOLOGY TOOLS TO EVALUATE AND INTERVENE TO IMPROVE HEALTHCARE DELIVERY / Poster Discussion Session / Tuesday, May 17/02:15 PM-03:45 PM / Room 3009/3011 (West Building, Level 3), Moscone Center Sensitivity and Specificity of the Visual Smartboard for the Recognition of Sepsis in Admitted Patients at the Hamilton General Hospi...

Introduction Sepsis is a dysregulated host response to infection characterised by activation of proinflammatory and procoagulant mechanisms. Protein C (PC)’s activity as an anticoagulant and antiinflammatory molecule makes it an appealing target for sepsis biomarker studies. To date, there has been no systematic review of PC as a sepsis biomarker....

Introduction Sepsis, the life-threatening immune response to infection, affects millions of people annually. Understanding of the factors associated with the development of sepsis is crucial for improving population health and public health efforts; in particular, literature exploring the relationship between sepsis and social determinants of healt...

The Foundation of Student Science and Technology is pleased to announce another successful year for our Research Co-Op Program. Two student participants, Fatima Sheikh and Melanie Manning, share their insightful testimonials in this month’s journal issue, noting their learning experiences about themselves and their future career choices in the scie...

Adult scoliosis can be classified into two groups, either degenerative scoliosis or idiopathic scoliosis. These two types of scoliosis vary in patient age, progression, and physical presentation. In adult idiopathic scoliosis, spurs form as a result of the onset of arthritis in the joints of the spine, resulting in back pain and in many cases defor...