Fatima AlZahra'a Alatraktchi

Fatima AlZahra'a Alatraktchi
Roskilde University · Department of Science and Environment

PhD

About

18
Publications
4,657
Reads
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572
Citations
Citations since 2017
9 Research Items
528 Citations
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2017201820192020202120222023050100150
2017201820192020202120222023050100150

Publications

Publications (18)
Article
Full-text available
Prostate cancer (PCa) is the second most common cancer in men and one of the leading causes of cancer-related deaths. Early detection is the key to successful treatment and provides the greatest chance to cure the patient. Currently, early detection involves screening for prostate-specific antigen levels in blood, which is not a tumor-specific biom...
Article
Pseudomonas aeruginosa is a waterborne ubiquitous opportunistic pathogen that can be fatal for immunocompromised patients. Here, we report the use of paper-based screen-printed sensors for the electrochemical detection of P. aeruginosa in water sources in only 14 seconds. P. aeruginosa is identifiable by its unique biomarker pyocyanin, which is red...
Article
Full-text available
Pseudomonas aeruginosa is an environmental pathogen that can cause severe infections in immunocompromised patients. P. aeruginosa infections are typically treated with multiple antibiotics including tobramycin, ciprofloxacin, and meropenem. However, antibiotics do not always entirely clear the bacteria from the infection site, where they may remain...
Article
Full-text available
The outbreak of the coronavirus disease (COVID-19) pandemic caused by the novel coronavirus (SARS-CoV-2) has been declared an international public health crisis. It is essential to develop diagnostic tests that can quickly identify infected individuals to limit the spread of the virus and assign treatment options. Herein, we report a proof-of-conce...
Article
Full-text available
Pseudomonas aeruginosa (PA) is a pathogen that is recognized for its advanced antibiotic resistance and its association with serious diseases such as ventilator-associated pneumonia and cystic fibrosis. The ability to rapidly detect the presence of pathogenic bacteria in patient samples is crucial for the immediate eradication of the infection. Pyo...
Article
Pyocyanin is a virulence factor solely produced by the pathogen Pseudomonas aeruginosa. Pyocyanin is also a redox active molecule that can be directly detected by electrochemical sensing. A nanograss (NG) based sensor for sensitive quantification of pyocyanin in sputum samples from cystic fibrosis (CF) patients is presented here. The NG sensors wer...
Article
Full-text available
Pyocyanin is a toxin produced by Pseudomonas aeruginosa. Here we describe a novel paper-based electrochemical sensor for pyocyanin detection, manufactured with a simple and inexpensive approach based on electrode printing on paper. The resulting sensors constitute an effective electrochemical method to quantify pyocyanin in bacterial cultures witho...
Data
Experimental data. Experimental data on the calibration, sensor comparison and PAO1 growth. (XLSX)
Article
Full-text available
The association of smart mobile devices and lab-on-chip technologies offers unprecedented opportunities for the emergence of direct-to-consumer in vitro medical diagnostics applications. Despite their clear transformative potential, obstacles remain to the large-scale disruption and long-lasting success of these systems in the consumer market. For...
Article
The ecotoxicity of platinum nanoparticles (PtNPs) widely used in for example automotive catalytic converters, is largely unknown. This study employs various characterization techniques and toxicity endpoints to investigate PtNP toxicity towards the green microalgae Pseudokirchneriella subcapitata and Chlamydomonas reinhardtii. Growth rate inhibitio...
Article
Aim: Pseudomonas aeruginosa is a pathogen that is prevalent in serious infections in compromised patients worldwide. A unique virulence factor of this bacterium is the redox-active molecule pyocyanin, which is a potential biomarker for the identification of P. aeruginosa infections. Here we report a direct, selective and rapid detection technique...
Article
Full-text available
Pyocyanin is a virulence factor uniquely produced by the pathogen Pseudomonas aeruginosa. The fast and selective detection of pyocyanin in clinical samples can reveal important information about the presence of this microorganism in patients. Electrochemical sensing of the redox-active pyocyanin is a route to directly quantify pyocyanin in real tim...
Conference Paper
Full-text available
In this paper we demonstrate a novel culturing system for brain slices and neuronal cells, which can control the concentration of nutrients and the waste removal from the culture by adjusting the fluid flow within the device. The entire system can be placed in an incubator. The system has been tested successfully with brain slices and PC12 cells. T...
Article
Full-text available
This article presents a novel membrane-based sensor for real-time electrochemical investigations of cellular- or tissue cultures. The membrane sensor enables recording of electrical signals from a cell culture without any signal dilution, thus avoiding loss of sensitivity. Moreover, the porosity of the membrane provides optimal culturing conditions...
Article
The nano-decoration of electrode with nanoparticles is one effective way to enhance power output of microbial fuel cells (MFCs). However, the amount of nanoparticles used for decoration has not been optimized yet, and how it affects the microbial community is still unknown. In this study, different densities of gold (Au) nanoparticles were sputtere...
Article
Microbial fuel cells (MFCs) have applications possibilities for wastewater treatment, biotransformation, and biosensor, but the development of highly efficient electrode materials is critical for enhancing the power generation. Two types of electrodes modified with nanoparticles or grass-like nanostructure (termed nanograss) were used. A two-chambe...

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