Fatih Gül

Igdır Üniversitesi

1,5,9-epideoxyloganic acid (ELA) was isolated from the aerial parts of endemic Nepeta aristata Boiss Et Kotschy Ex Boiss crude extract (methanol:chloroform) using silica gel (hexane, chloroform, ethyl acetate, and methanol) and sephadex LH-20 (65% methanol-35% chloroform) columns. Activity-guided isolation was performed on methanol sub-fractions wi...

The essential and fatty oils were investigated and a quantitative analysis of the root, green and stem parts of F. Longipedunculata was performed by GC-MS and HPLC-TOF/MS and their antioxidant (DPPH method) activities and potential binding of phytochemicals against SARS-CoV-2 nucleocapsid were determined using Molegro Virtual Docker software. In th...

Background: Luffa cylindrica is a plant that is widely distributed in Africa and Asia and can be grown in regions with tropical or subtropical climates. Few patents dealt with Loofah biological properties, including some functional foods formulated from its leaves. Objective: This study aimed to structurally and functionally characterize the bioac...

Water stress is of the major abiotic stress factors shifting the plant metabolism and subsequently plant growth, development and yield. In order to reduce the adverse impacts of water stress, herewith the study, the effects of salicylic acid priming on water stressed basil plants has been evaluated through physiological, biochemical and yield param...

Background: Pistacia atlantica Desf. (Anacardiaceae) has various applications for dietetic and medicinal purposes. Objective: The aim of the present study was to evaluate antioxidant, antiproliferative and anticholinesterase activities of different extracts from leaf and stem of Pistacia atlantica Desf. Methods: The antioxidant activity was perfo...

To elaborate a strategy of integrated aphids management associated with cereals in Algeria, the insecticidal activity of the essential oil of Mentha rotundifolia against two aphids, namely Rhopalosiphum padi and Sitobion avenae was evaluated under laboratory conditions. Analysis of the essential oil of M. rotundifolia by Gas Chromatography/Mass Spe...

In the scope of this study, we have investigated fumigant and contact toxicity effects of Satureja boissieri Hausskn. ex Boiss. essential oil against Sitophilus granarius L. (Coleoptera: Curculionidae) and Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae). The fumigant and contact toxicity experiments were carried out with the adults of Si...

Ethnopharmacology relevance: Cymbopogon schoenanthus (C. schoenanthus) and Helianthemum lippii (H. lippii) are Saharan species found in the South West of Algeria, in the region of Bechar. Both plants are used in traditional medicine to treat gastrointestinal disorders. Objective: The aim of our study was to characterize the composition of the et...

Salt stress imposes major limitations on the growth, development, crop productivity, and quality in many regions of the world. Therefore, the studies concerned with salinity and its effects on plants are of the fundamental interests for agricultural issues. Herein, the present study was designed to investigate the effects of different salt compound...

It is aimed to investigate the cytotoxic effects of the various extracts from the leaf and seed of Centaurea derderiifolia on the growth human cervical adenocarcinoma (HeLa) cells by xCELLigence method and to isolate the cytotoxic constituents. The results showed that subfractions 2 and 3 exhibited remarkable inhibitory effect against HeLa (IC50 <...

The present work was conducted to find the physicochemical properties, chemical components and antioxidant capacity of kiwifruit hydroalcoholic extracts (B-31, HO-1-14, J-242, Bruno, Greenlight, Hayward, Monty, Topstar) grown Yalova, Turkey. Phytochemical tests were performed to determine total phenolic, flavonoid and ascorbic acid. Moreover, the k...

Pre-fractionation and contemporary spectroscopic analysis provides important clues with regard to synergistic and antagonistic effects as well as biological activities in complex multi-mixtures, especially natural products. Phytochemical contents of the Chrysophthalmum montanum root extracts were analyzed by gas chromatography–mass spectrometry and...

Lasia spinosa (L.) Thwaites is a widely used ethnomedicinal plant in Bangladesh. In this study, we investigated phenolic contents, volatile compounds and fatty acids, and essential oil components of extracts prepared from aerial parts of the plant. The main volatile compounds were methyl ester of oleic acid, palmitic acid and stearic acid as determ...

Mint has been used extensively in traditional medicines, spices, and herbal teas throughout the world. Isolation of flavonoids from Mentha spicata and quantification of these compounds in selected clones of Turkish mints landraces were achieved. M. spicata was dried in shade and then boiled in water. After filtration, the aqueous extract was partit...

Origanum, widely used for food and pharmaceutical industries, belonging to the Lamiaceae family, is an aromatic and medicinal plant. The aerial parts of the Origanum onites L. were dried at shade and extracted with methanol. Rosmarinic acid, gentisic acid, 4-hydroxybenzoic acid, protocatechuic acid, caffeic acid, vanillic acid, 4-hydroxylbenzaldehy...

Background and Purpose: Hypericum species (Guttiferae) are of important for developing pharmaceutical drugs as herbal remedies, due to fact that their rich phytochemical compounds, besides, wide range of biological properties. Among the species, Hypericum capitatum CHOISY var. capitatum CHOISY, an endemic medicinal plant, naturally distributes in t...

This study aimed to determine the composition andthe antifungal activity of the essential oils of Vaccinium myrtillus and Laurus nobilis plants. In the study, 22 components were identified in the essential oil of V. myrtillus, which represented 100% of the total essential oils. Accordingly, 1,8-cineole (41.07%), β-Linalool (12.72%), α-Pinene (12.17...

Abstract: The chemical composition and fatty acid contents of Cirsium arvense subsp. vestitum aerial parts (flowers (CaF) and stem-leaf (CaSL)) was examined in this study. Aerial parts of this plant were extracted with various solvents such as hexane (CaFH and CaSLH), chloroform (CaFC and CaSLC) and methanol / chloroform (CaFMC and CaSLMC). Fatty a...

In this study, the essential oils of Heracleum platytaenium (Apiaceae) species in Sinop region of northern Turkey were investigated and 27 components were identified by GC, GC-MS. Essential oils were obtained by Clevenger-type hydrodistilled from the aerial parts of plants collected from the natural habitats. The essential oils yield is very low an...

Echinacea pallida (Nutt.) Nutt., Melissa officinalis L. (lemon balm), Hypericum perforatum L. (St. John's wort) and Sideritis syriaca L. are valuable for its pharmaceutical, medicinal and agricultural properties. These plants were extracted with methanol/chloroform (1:1) solvent, filtered, and solvents were removed by rotary evaporator to get four...

The current work evaluated the chemical compositions of the essential oils (EOs) extracted from Mentha longifolia subsp. typhoides (Briq.) Harley var. typhoides PH. Davis, Mentha spicate L. subsp.spicata, Mentha longifolia (L.) Hudson subsp.longifolia and Mentha villoso nervata Opiz from gowning in the different locations of Tokat. The antioxidant...

Abstract: Natural products derived from plants play a significant role in drug discovery due to the revealing a large variety of pharmaceutical effects. Kickxia spuriawas collected from Bingol, Turkey. Aerial parts of the plant were boiled in water for 2 h then extracted with ethyl acetate. After evaporation of the solvent by rotary evaporator, the...

Background: The use of plants for the treatment, cure and prevention of diseases is one of the oldest medicinal practices of humanity. These plants are able to produce much diversified natural compounds (e.g. alkaloids, polyphenols, etc.) which have many pharmaceutical applications. Objective: The aim of the present study was to evaluate the antiox...

The study was to investigate chemical composition , antibacterial, the antioxidant and antifungal activity of essential oil from Thymbra spicata L. (T. spicata L.). T. spicata L. essential oil fourteen components were determined. The basic components of the essential oil were determined carvacrol (78.53%), γ-terpinene (10.42%) and p-Cymene (5.49%)....

Background Algeria has a particular geographical position with a wide band of very varied vegetation including the aromatic and medicinal plants. These plants are able to produce much diversified natural compounds, which can be very useful health care and treatment of diseases. Objective This study was carried out to evaluate the antioxidant capac...

p>The prevention and treatment of the cancer using plants have attracted increasing interest. The present study was aimed to determine the phenolic compounds of Genista ferox using HPLC-TOF/MS and the anti-oxidant acti-vity associated with anti-cancer activity against human cervical adenocarcinoma (HeLa) cell line. Total anti-oxidant capacities of...

The present work aimed to determine the antioxidant and antiproliferative potential of Luffa cylindrica fruits collected at two different maturation stages and to identify and compare their functional components composition. The methanolic extracts of L. cylindrica fruits harvested at 60 to 65 days after seeding (S1) and 85 to 90 days after seeding...

Aim and objective: This study aimed to quantify phenolic compounds in ethyl acetate and n-butanol extract of Centaurea choulettiana Pomel (Asteraceae) leaves and flowers; compare the antioxidant activity of their extracts, identification and quantification of their phenolic acids. Materials and methods: Both organs extracts of Centaurea choulett...

ABSTRACT In recent decade, liquid chromatography coupled with mass spectrometry (LC–MS) has become the most selective techniques for rapid screening and characterization of known and unknown constituents from the extracts of medicinal plants. Centaurea species are known for their multiple biological activities. With the aim of estimating the chemic...

The aim of this study was to isolate the active components from the essential oil (EO) of Satureja boissieri and to investigate the cytotoxic effects of these components on human cervical epithelioid carcinoma (HeLa) cell line. The major components of EO were found to be p-cymene (23.15%), γ-terpinene (22.84%), thymol (18.96%) and carvacrol (21.25%...

Context: Hertia cheirifolia L. (Asteraceae) is traditionally used in Northern Africa to treat various inflammatory infections. However, few studies on this plant have been reported. Objective: The anti-inflammatory activity of methanol extract of H. cheirifolia leaves was investigated using different experimental models. Materials and methods:...

In this study, the effect of Mougeotia nummuloides and Spirulina major on Vero cells (African green monkey kidney), C6 cells (rat brain tumor cells) and HeLa cells (human uterus carcinoma) was investigated in vitro. The antiproliferative effect of the methanol extract of M. nummuloides and S. major compared with 5-fluorourasil (5-FU) and cisplatin...

Background: Ocimum basilicum L., commonly known as sweet basil, is an important aromatic plant cultivated in many parts of the world for its essential oil. Basil does not show natural distribution in Turkey but they are cultivated as medicinal, seasoning or oil plants especially in the western and southern Anatolia. In this study, introduction of n...

Echinacea is valuable for its pharmaceutical, medicinal and agricultural properties. Flowers and leaves of Echinacea purpurea (L.) Moench and Echinacea pallida (Nutt.) Nutt. were extracted with methanol, filtered, and solvents were removed by rotary evaporator to get four separate extracts. The flowers and leaves of both plants were boiled in water...

The composition of fatty acids and insecticidal effects were performed for the Turkish mosses Dicranum scoparium, Hypnum cupressiforme, Polytrichastrum formosum, Homalothecium lutescens and the Turkish liverwort Conocephalum conicum. All structures were determined by means of gas chromatography and gas chromatography-mass spectrometry techniques. A...

The composition of fatty acids and insecticidal effects was performed for the Turkish mosses Dicranum scoparium, Hypnum cupressiforme, Polytrichastrum formosum, Homalothecium lutescens and the Turkish liverwort Conocephalum conicum. All structures were determined by means of gas chromatography and gas chromatography-mass spectrometry techniques. Th...