Fatemeh Eghbalian

• Professor of neonatology
• Hamedan University of Medical Sciences

Background This interventional study aimed to assess the impact of combining probiotics with phototherapy compared to using phototherapy alone on bilirubin reduction in term neonates hospitalized in neonatal wards in hospitals of western Iran. Methods This clinical trial study included 150 term neonates with a gestational age of 37 to 42 weeks, bi...

Mother’s self-efficacy in breastfeeding is among the factors that can affect the initiation and continuation of breastfeeding. This study is aimed at evaluating predictors of breastfeeding self-efficacy in primiparous women in the west of Iran, Hamadan. The present cross-sectional study recruited 170 women who had been delivered within the past 24...

Introduction Jaundice is one of the most common problems during infancy. It is believed that breast milk jaundice is one of the reasons for the persistence of jaundice after 14 days of prolonged jaundice. This study evaluates the effect of Clofibrate and phototherapy on prolonged jaundice originating from breast milk in term and healthy neonates....

Background: Birth injuries occur during the birth process. The progress made in birth care and prenatal diagnosis has reduced the prevalence of birth injuries around the globe. Objectives: This study aimed to determine the prevalence of birth injuries and their determining factors in Hamadan Fatemieh Hospital, 2020 - 2021. Methods: In this case- co...

Background: The current study is aimed at updating the observational studies on the relationship between threatened abortion and the risk of ASD. Methods: The search keywords were covered in three electronic databases PubMed, Web of Science, and Scopus up to April 2022. The modified Newcastle-Ottawa scale (NOS) was applied to detect the quality...

Background: Acute lymphoblastic leukemia (ALL) as the most common malignancy in children is associated with high mortality and significant relapse. Currently, the non-invasive diagnosis of pediatric ALL is a main challenge in the early detection of patients. In the present study, a systems biology approach was used through network-based analysis to...

Background: Phototherapy is the most common form of treatment and prevention of neonatal nonconjugated hyperbilirubinemia. It seems that intravenous fluid therapy as a complementary method of phototherapy can accelerate the healing process in affected infants. This study aimed at investigating intravenous fluid therapy's effect in decreasing serum...

Background: Hypoxic-ischemic encephalopathy (HIE) is a leading cause of mortality and morbidity in neonates. Head cooling is considered the standard treatment that reduces mortality and morbidity by decreasing the adverse effects of the disease. Some medicines having neuroprotective properties may be beneficial in treating HIE. Objectives: We aimed...

In neonates, bilirubin tends to be deposited in body tissues, especially the skin and mucous membranes. Jaundice is an early symptom of bilirubin excretion disorders. Therefore, the aim of this study was to investigate the effect of clofibrate on reducing neonatal jaundice. In this systematic review, international databases, including PubMed, Scopu...

Objectives: Neonatal jaundice or hyperbilirubinemia is one of the common findings in neonatal medicine. Severe disease can cause neurological damage and even Kernicterus. Magnesium ion is the most important N-methyl-D-aspartate receptor antagonist. The most commonly used treatment for jaundice is phototherapy, but the effect of phototherapy on ser...

Purpose: This study aimed to evaluate the effect of probiotics and phototherapy combined application in comparison with phototherapy alone on bilirubin reduction in term neonates hospitalized in Iran. Methods: This clinical trial study included 150 term neonates diagnosed with neonatal jaundice. Patients were equally assigned to two groups of photo...

Introduction So far, no study has been conducted in Iran on the effect of COVID-19 on neonates. Therefore, the present cross-sectional study has been evaluated to determine the clinical manifestations and outcomes in neonates infected with COVID-19 in the west of Iran. Materials and Methods The present cross-sectional study was conducted among neo...

Introduction Hyperbilirubinemia is a common complication among neonates. The objective of this cross-sectional study was the prevalence of glucose 6-phosphate dehydrogenase (G6PD) deficiency among neonates with hyperbilirubinemia in the west of Iran. Materials and Methods In this retrospective cross-sectional study, the records of neonates with hy...

Introduction : Breast milk jaundice is considered as the most common cause for neonatal jaundice; however, its epidemiological aspects in some population remain unclear. Objectives : The present study aimed to assess the prevalence of breast milk jaundice and its main determinant among a group of neonates in western Iran. Patients and Methods : Thi...

Introduction : The increased risk for childhood asthma in children suffering from hyperbilirubinemia, and those who underwent phototherapy has attracted enormous interest. Objectives : In this study, we attempted to explain the relationship between childhood asthma and phototherapy. Patients and Methods : This case-control study was performed on ch...

[This corrects the article on p. 152 in vol. 10, PMID: 31263664.].

Objectives: Herbal remedies such as purgative manna are used to treat neonatal jaundice. In this study Bilineaster drop (purgative manna) and phototherapy, and phototherapy treatment alone were compared by assessing phototherapy duration and number of days in hospital. Methods: There were 150 consecutive term neonates with jaundice, weighting from...

Background & Objective: Early detection of neonatal hearing disorders is a suitable measure of speech and behavioral development. The aim of this study was to determine the prevalence of hearing disorder in high-risk neonates treated in a neonatal intensive care unit (NICU). Materials & Methods: This descriptive study was performed on 150 neonates...

Objectives: Herbal remedies such as purgative manna are used to treat neonatal jaundice. In this study Bilineaster drop (purgative manna) and phototherapy, and phototherapy treatment alone were compared by assessing phototherapy duration and number of days in hospital. Methods: There were 150 consecutive term neonates with jaundice, weighting fr...

strong>Background: Urinary tract infection in infants is associated with septicemia and genitourinary anomalies. This study was aimed at investigating the frequency, clinical signs, and anomalies in infants hospitalized for urinary tract infection. Methods: This cross-sectional study was conducted on all infants with urinary infection who were hos...

Background: Transient tachypnea of the newborn (TTN) is one of the important causes of neonatal respiratory distress and hospitalization in the neonatal intensive care unit (NICU). Objectives: The current study aimed at identifying the risk factors of TTN in a single tertiary care center. Methods: The current prospective, case-control study was con...

Objective: Due to the effects of massage on various laboratory parameters (including those related to jaundice) in infants and the expansion of existing studies to achieve effective and safe therapy in the treatment of neonatal jaundice, this study aimed to investigate the effect of massage on bilirubin levels in cases of neonatal jaundice. Metho...

Background: Multiple pregnancies are responsible for the increased risk of maternal and neonatal morbidity and mortality. This study aimed to compare the perinatal outcome between multiple and singleton pregnancies. Materials and Methods: This is a retrospective cohort study. A sample of 50 multiple birth neonates- born in Fatemieh Hospital of Hama...

Neonatal seizures are the most common neurological symptoms and often signal an underlying serious neurologic condition. This study determines the frequency of neonatal seizure, predisposing factors, and brain computed tomography (CT) scan findings. In a descriptive cross-sectional study, we evaluated all neonates with seizures who had been hospita...

Respiratory distress syndrome (RDS) is one of the most important causes of mortality and morbidity in premature newborns. The aim of this study was to determine the effect of body position on oxygen saturation in hospitalized premature infants with RDS. From June 2010 to December 2012, 69 premature infants with RDS were evaluated in an intervention...

Background: H1N1 virus is a novel subtype of influenza virus A. Sudden changes in this virus can make different clinical symptoms. So in this study we determine the prevalence of influenza virus A/H1N1 infection in children with the age <16 and clinical symptoms of them in Hamadan in 2010 and association of some laboratory tests with H1N1. Methods:...

Background and Aim Bacterial diarrhea is very common in particular in devoloping countries and is still one of the most causes of mortalities in children. The aim of present study was to identify the most common of bacterial agents causing acute bacterial diarrhea in children under 14 years old and detection of their resistance to antibiotics. Meth...

This study tried to assess sensitivity, specificity, positive and negative predictive value of procalcitonin for diagnosis of neonatal bacterial infections. This prospective cross sectional study was carried out during an 18-month period in NICU and neonatal wards of Besat Hospital in Hamedan province, Iran. 39 symptomatic infants with clinical and...

This study evaluates the platelet count changes in neonates with hyperbillirubinemia who re-ceived phototherapy. In this Prospective Descri-ptive-cross sectional study 144 full term new-borns with indirect hyperbillirubinemia who re-ceived phototherapy in neonatal ward of Bessat hospital in Hamedan province of Iran were stu-died from September 2007...

Background and aims: Bacterial infections are one of the main problems for pediatric diseases in the third world countries. Therefore, the aim of study was the evaluation of frequency of bacterial infections in children and detection of antibiotics resistance patterns of bacteria in Hamadan, West of Iran. Methods: This study was performed on 6391 c...

Hypoxic-ischemic encephalopathy (HIE) is brain damage from a shortage of oxygen or blood flow to the tissues[1,2] and is characterized by clinical and laboratory evidence of acute or subacute brain injury due to asphyxia[1-6]. It is a major contributor to neonatal death and morbidity[4-6]. 15%-20% of HIE cases die during the neonatal period and 30%...

Background Allgrove syndrome is a rare autosomal recessive condition characterized by adrenal insufficiency, achalasia, alacrima and occasionally autonomic disturbances. Mutations in the AAAS gene, on chromosome 12q13 have been implicated as a cause of this disorder. Case(s) Presentation We present various manifestations of this syndrome in two re...

Bacterial pathogens and drug resistance are different in hospitals of each country. In this study we determined bacterial path-ogens and drug sensitivity in the neonatal ward and neo-natal intensive care unit (NICU) in Ekbatan hos-pital in Hamedan. This cross-sectional descrip-tive study was done on 1150 hospitalized neo-nates in neonatal and NICU...

Congenital epulis (CE) is a rare tumor of the newborn, also known as granular cell tumor or congenital gingival granular cell tumor because of its histologic features. Neumann first described CE in 1871. Epulis is seen only in the newborn and is a different entity from other granular cell tumors. CE has a female predilection with 8:1 ratio. Epulis...

Esophageal atresia is often associated with other anomalies. Hereditary and environmental factors may influence the incidence of associated anomalies, particularly of the urogenital system. We had 63 neonates with esophageal atresia admitted to 2 centers in Hamadan, Iran, from 2002 to 2008. They were 38 girls (60.3%) and 25 boy (39.7%). Tracheoesop...

Objective: The objective of this study was to assess the prevalence of hearing impairment by automated auditory brain stem response (AABR) in newborns admitted to an intensive and intermediate care unit and to analyze the associated risk factors.Methods: An observational cross-sectional study was conducted between January 2005 and January 2006. 834...

Objective The aim of the present study was to evaluate the etiology and frequency of neonatal seizure in hospitalized neonates. Materials and Methods In this descriptive, cross-sectional study, we evaluated 1295 neonates with seizures admitted to neonatal and NICU wards in our center. Data was collected on age, sex, birth weight, serum levels of ca...

In recent years, the theory that on-line clinical decision support systems can improve patients' safety among hospitalised individuals has gained greater acceptance. However, the feasibility of implementing such a system in a middle or low-income country has rarely been studied. Understanding the current prescription process and a proper needs asse...

Objective: Waardenburg syndrome is a rare disease characterized by sensorineural deafness in association with pigmentary anomalies and defects of neural- crest- derived tissues. Depending on additional symptoms, WS is classified into four types, WS1, WS2, WS3 and WS4. Waardenburg syndrome type 4, also called Waardenburg- Shah syndrome, is a very ra...

Jaundice is a common clinical problem in neonatal period which may result in brain damage even in healthy full term newborns, when it is severe. The aim of this study was to characterize the therapeutic effect of clofibrate in full term neonates who present with nonhemolytic jaundice. A clinical controlled study was performed on 60 full term neonat...

Objective: Aplasia Cutis Congenita (ACC) is a rare disorder with a complicated pattern of inheritance. Babies are born with the absence of certain layers of skin. It most commonly manifests as a solitary defect on the scalp, but sometimes it may occur as multiple lesions. The affected area is typically covered with a thin, transparent membrane. The...

Objective: Glucose-6- phosphate dehydrogenase (G6PD) deficiency is an inherited deficiency that may be the cause of neonatal jaundice. Our aim was to study the prevalence of G6PD deficiency without hemolysis in relation to neonatal jaundice.Material & Methods: This prospective descriptive study has been conducted on 272 icteric newborns admitted to...

Background: Neonatal mortality rate is one of the main health problems which is affected by prenatal status, maternal, fetal and perinatal conditions. Low birth weight (LBW) is one of the main causes of neonatal and infantile mortality. The aim of this study is an evaluation of the LBW causes in neonates. Methods: This descriptive cross sectional s...

Bakground: Phototherapy plays a significant role in the treatment and prevention of hyperbilirubinemia as well as the management of subsequent complications in the newborn. However, this treatment modality may itself result in the development of hypocalcaemia and create serious complications including convulsion and related conditions. Objective: T...

Sixty patients with different cardiac diseases and healthy volunteers were given omega-I-123-heptadecanoic acid (HDA) intravenously. Tracer kinetics were followed for 90 min, and tracer elimination curves were obtained regionally. In addition, circumferential washout profiles were evaluated for 26 patients and interpolative as well as constant back...

Left ventricular performance at rest and during supine symptom-limited exercise was determined by radionuclide ventriculography (RNV) in 65 subjects of the age of 65 years or older. Eleven subjects had no evidence of coronary artery disease (CAD) by history or submaximal stress ECG. In this control group left ventricular ejection fraction (LV-EF) i...